Cabergoline is an effective preventative treatment for ovarian hyperstimulation syndrome (OHSS). It works by inhibiting the phosphorylation and signaling of vascular endothelial growth factor receptor-2, which is involved in the pathophysiology of OHSS. Studies show cabergoline reduces the risk and incidence of OHSS when taken starting on the day of hCG trigger or egg retrieval, especially for moderate OHSS. It is considered safe for use in assisted reproduction and does not negatively impact pregnancy outcomes. While cabergoline is effective for prevention, its role in treatment of late onset OHSS is limited.