This document discusses health system failures in combating tuberculosis (TB) in Southern Africa, focusing on miners. It applies the Flagship Framework's "control knobs" (financing, payment, organization, regulation, behavior) to analyze TB control programs. Miners in Southern Africa have the highest TB rates in the world due to occupational and socioeconomic risks. While treatment is effective, health systems struggle with social determinants like poverty, multi-sectoral issues, and long treatment times. The analysis recommends a patient-centered approach involving whole-of-government and multi-sectoral cooperation to better address the underlying drivers fueling the TB epidemic.
Role of pharmacist in prevention and control of pandemicDr. Sharad Chand
This PowerPoint slide describes the major role-play of pharmacists during the disease outbreak (Pandemic diseases). This slide summarizes the roles of several pharmacists ranging from drug store management to the disaster risk management.
Medical demography is concerned with the consequences of health, sickness, accidents, disability, and death for the size, composition, and structure of the population; and with the economic, social, and policy impacts of those dynamics.
Epidemiological data and methods can be used by medical demographers as part of their population modeling methods.
Introduction
Uses and aims of epidemiology
Qualification
Jobs included
List of skills
Role of epidemiologists
Specializations
Courses offered
Public health significance
Role of pharmacist in prevention and control of pandemicDr. Sharad Chand
This PowerPoint slide describes the major role-play of pharmacists during the disease outbreak (Pandemic diseases). This slide summarizes the roles of several pharmacists ranging from drug store management to the disaster risk management.
Medical demography is concerned with the consequences of health, sickness, accidents, disability, and death for the size, composition, and structure of the population; and with the economic, social, and policy impacts of those dynamics.
Epidemiological data and methods can be used by medical demographers as part of their population modeling methods.
Introduction
Uses and aims of epidemiology
Qualification
Jobs included
List of skills
Role of epidemiologists
Specializations
Courses offered
Public health significance
Lesson learned and not learned in COVID -19 PANDEMICHarivansh Chopra
in march 2019 WHO declared covid -19 as pandemic and since than we have come long way to understand the epidemiology of covid -19. we also have learned quite a number of unpleasant/pleasant lessons in the control and management of covod -19. vaccines have been developed by a quite rapid pace across the globe and similarly vaccine hesitancy and utilisation has also been seen across the globe . this is a very simple presentation highlighting the the importance of correct knowledge and strategies to control this pandemic
COUNTDOWN on WHO 2020 Targets: A Focus on helminthiasisCOUNTDOWN on NTDs
Professor Russell Stothard, COUNTDOWN's programme Director attended the Swiss Tropical and Public Health Institute's Winter symposium titled 'Helminth Infection - from Transmission to Control'
Keynote address by Dr. Eric Goosby of UCSF, presented at CFAR HIV Research in International Settings (CHRIS) meeting in San Diego, October 1, 2014. Dr. Goosby discussed. "Global Health Delivery and Diplomacy: The Long Road to Sustainable Programs."
Running head: TUBERCULOSIS 1
TUBERCULOSIS 2
Tuberculosis
NRS-427VN | Epidemiology and Communicable Disease
8/26/18
Tuberculosis
About 33% in our existence's people is considered to have been tainted with tuberculosis (TB), new attacks are symbolized in no under 1% of the people every year". In 2016, a standard 1.5 million fatalities associated with TB have took place, the lion's talk about which are from younger looking countries over the world. As this quantity has been reducing, unnecessarily various have been sullied. The best center is situated in the Asian and African countries, at 80%. Within the USA, 5-10% of the individuals studies constructive. With tuberculosis taking after second behind HIV/Helps in most common deaths from powerful ailment, they have transformed into an over-all exchange. Understanding the annals, seeing the signals and appearances, evolved treatment alternatives, and neutralizing activity, will spread this disease to an even of control.
Since the start, tuberculosis has been accessible. Most quick unambiguous affirmation of the malady has been dated around 17,000 years before, in stays of a bison in Wyoming. Effective treatment of tuberculosis has finished up being bothersome and long. Chemical manifestations of the mycobacterium cell dividers and bizarre form, restricts most against microbial alternatives. Most typically used is Isoniazid and Rifampicin. Advised estimations of treatment, for new starting point, are half a year of blend hostile to infections operators. 8 weeks of rifampicin, isoniazid, pyrazinamide, and ethambutol drugs. Together with the latest four a few months of just rifampicin and isoniazid"(Wikipedia, 2015, p. 12).For the individuals who have idle TB receive only a sole against microbial.
This estimation ruins the inert TB to wrap up aspect. As this move out estimations of hostile to infections specialists can be difficult, direct observed treatment is preferred by WHO (World Health Corporation, 2015). Facts have exhibited that folks, who are depended after to adopt their medicine, will miss organized estimations. Immediate discernment treatment contains having an interpersonal protection employee watch the individual taking their remedies. As this is dreary, using diverse contraptions of acknowledgment is necessary. Such overhauls can sign up for booked calls or digital notices. By not doing medication regimens, put others at peril to finding this sickness.
Those in close closeness to specific with tuberculosis are in an especially high danger to finding the opportunity to be debased. Besides, with HIV/Supports hold the most hoisted risk element of all. Early on area and treatment, with fitted hindrances of these polluted is an integral.
Friendly determinants ...
Lesson learned and not learned in COVID -19 PANDEMICHarivansh Chopra
in march 2019 WHO declared covid -19 as pandemic and since than we have come long way to understand the epidemiology of covid -19. we also have learned quite a number of unpleasant/pleasant lessons in the control and management of covod -19. vaccines have been developed by a quite rapid pace across the globe and similarly vaccine hesitancy and utilisation has also been seen across the globe . this is a very simple presentation highlighting the the importance of correct knowledge and strategies to control this pandemic
COUNTDOWN on WHO 2020 Targets: A Focus on helminthiasisCOUNTDOWN on NTDs
Professor Russell Stothard, COUNTDOWN's programme Director attended the Swiss Tropical and Public Health Institute's Winter symposium titled 'Helminth Infection - from Transmission to Control'
Keynote address by Dr. Eric Goosby of UCSF, presented at CFAR HIV Research in International Settings (CHRIS) meeting in San Diego, October 1, 2014. Dr. Goosby discussed. "Global Health Delivery and Diplomacy: The Long Road to Sustainable Programs."
Running head: TUBERCULOSIS 1
TUBERCULOSIS 2
Tuberculosis
NRS-427VN | Epidemiology and Communicable Disease
8/26/18
Tuberculosis
About 33% in our existence's people is considered to have been tainted with tuberculosis (TB), new attacks are symbolized in no under 1% of the people every year". In 2016, a standard 1.5 million fatalities associated with TB have took place, the lion's talk about which are from younger looking countries over the world. As this quantity has been reducing, unnecessarily various have been sullied. The best center is situated in the Asian and African countries, at 80%. Within the USA, 5-10% of the individuals studies constructive. With tuberculosis taking after second behind HIV/Helps in most common deaths from powerful ailment, they have transformed into an over-all exchange. Understanding the annals, seeing the signals and appearances, evolved treatment alternatives, and neutralizing activity, will spread this disease to an even of control.
Since the start, tuberculosis has been accessible. Most quick unambiguous affirmation of the malady has been dated around 17,000 years before, in stays of a bison in Wyoming. Effective treatment of tuberculosis has finished up being bothersome and long. Chemical manifestations of the mycobacterium cell dividers and bizarre form, restricts most against microbial alternatives. Most typically used is Isoniazid and Rifampicin. Advised estimations of treatment, for new starting point, are half a year of blend hostile to infections operators. 8 weeks of rifampicin, isoniazid, pyrazinamide, and ethambutol drugs. Together with the latest four a few months of just rifampicin and isoniazid"(Wikipedia, 2015, p. 12).For the individuals who have idle TB receive only a sole against microbial.
This estimation ruins the inert TB to wrap up aspect. As this move out estimations of hostile to infections specialists can be difficult, direct observed treatment is preferred by WHO (World Health Corporation, 2015). Facts have exhibited that folks, who are depended after to adopt their medicine, will miss organized estimations. Immediate discernment treatment contains having an interpersonal protection employee watch the individual taking their remedies. As this is dreary, using diverse contraptions of acknowledgment is necessary. Such overhauls can sign up for booked calls or digital notices. By not doing medication regimens, put others at peril to finding this sickness.
Those in close closeness to specific with tuberculosis are in an especially high danger to finding the opportunity to be debased. Besides, with HIV/Supports hold the most hoisted risk element of all. Early on area and treatment, with fitted hindrances of these polluted is an integral.
Friendly determinants ...
OUTBREAK INVESTIGATION 1
OUTBREAK INVESTIGATION 2
Outbreak Investigation
Introduction
Epidemiology deals with the study of the determinants and distribution of disability or disease in the population groups (Szklo & Nieto, 2014). Epidemiology is one of the core areas in public health study and is essential for the evaluation of the efficacy of the new therapeutic and preventive modalities as well in the new organizational health care delivery patterns. I have for a long time developed a lot of interest in the area towards learning more on finding the causes of diseases and health outcomes in populations. Epidemiology views the individuals collectively, and the community is considered to be patient. The area of public health study is systematic, scientific, and data-driven in analyzing the pattern or frequency of the distributions and the risk factors or causes of specific diseases in the neighborhood, city, school, country, and global levels. Epidemiology handles various areas including environmental exposures, infectious diseases, injuries, non-infectious diseases, natural disasters and terrorism (Szklo & Nieto, 2014). Specifically, this paper explores epidemiology in addressing infectious disease, food-borne illness in the community. Also, the paper examines outbreak investigations as an intervention towards addressing the foodborne illness in the society. Further, an evaluation of the intervention and the expected results are discussed to examine or analyze the contributions of the intervention.
Foodborne Illness
Foodborne illness is any illness that results from food spoilage of the contaminated food. Food can be contaminated by the pathogenic bacteria, contaminated food, parasites, or viruses, as well as natural or chemical toxins including several species of beans, and poisonous mushrooms. In the United States, food-borne illness is estimated to impact negatively over 76 million people annually (Jones, McMillian, Scallan et al., 2007). This is translated to 5,2000 deaths, and 325,000 hospitalizations. However, the true incidence of food-borne illness is unknown. The majority of food-borne illness and most of the deaths are linked to “unknown agents” following the difficulties encountered in the diagnosis a foodborne disease. An estimated $7 billion is lost regarding productivity and medical expenses and is attributed to the most prevalent but diagnosable foodborne illnesses. Comment by Vetter-Smith, Molly J: Reference needed for this statement Comment by Vetter-Smith, Molly J: References needed for these statements
The under diagnosis in foodborne illnesses is further contributed by the majority who has the symptoms and signs of the disease but totally fail to seek medical attention. This circumstance coupled with the global and national distribution of foo.
INTRODUCTIONA pandemic is a global disease outbreak.EXAMPLES 1.pdfgalagirishp
INTRODUCTION:
A pandemic is a global disease outbreak.
EXAMPLES: 1) HIV/AIDS is an example of one of the most destructive global pandemics in
history.
2) Spanish influenza killed 40-50 million people in 1918.
3) In 2003, the severe acute respiratory syndrome (SARS) epidemic took the lives of nearly 800
people worldwide.
OBJECTIVES OF LOCAL, STATE AND FEDERAL GOVERNMENT:
ROLE OF FEDERAL GOVERNMENT:
The federal government has the central role in shaping all aspects of the health care sector.
Strong federal leadership, a clear direction in pursuit of common aims, and consistent policies
and practices across all government health care functions and programs are needed to raise the
level of quality for the programs’ beneficiaries and to drive improvement in the health care
sector overall.
The federal government plays a number of different roles in the health care arena, including
regulator; purchaser of care; provider of health care services; and sponsor of applied research,
demonstrations, and education and training programs for health care professionals. Each of these
roles can support the accomplishment of somewhat different objectives along the spectrum from
quality assurance to quality improvement to quality innovation.
PROVISION OF NECESSITIES:
If people are instructed to avoid public places, such as markets, stores, and pharmacies, or if
those places are required to close, there will be a need for people to procure food, medicine, and
other necessities in some other way. Similarly, shutting down mass transit may prevent people
from being able to get to those facilities that do remain open, and it could prevent some people
from being able to seek medical care. Such a situation also raises distributive-justice concerns
since those people with the least resources will be least likely to be able to procure additional
resources before closings occur.
Ideally governments would set up networks for the distribution of necessary provisions to
citizens’ homes, with a particular focus on those most in need. Such distribution should be
consistent and reliable, and it should provide necessities such as food and medicine for the
duration of social-distancing measures. It should also be conducted in such a manner as to
minimize interaction with potentially infectious people, and those people responsible for
distributing provisions should use infection-control precautions to decrease the likelihood that
they will spread disease. Transportation for medical care should be provided as needed by
personnel who are apprised of the risks involved in transporting potentially infectious people;
these personnel should be provided with protective equipment that will allow them to guard
themselves from the disease and to avoid spreading it to others. Similarly, a program should be
put in place for the removal of bodies from homes in a safe and efficient manner.
Resource constraints and logistical difficulties are likely to impede such a program in many
areas. Many gov.
In today's interconnected world, the term "pandemic" has become all too familiar. But what exactly does it mean, and why is it so significant? A pandemic can be defined as a global health crisis caused by the outbreak of an infectious disease that spreads across multiple countries or continents. It is a term that denotes the severity and scale of an epidemic.
To understand the significance of a pandemic, it is essential to differentiate between a pandemic and an epidemic. While both refer to the spread of infectious diseases, an epidemic is typically confined to a specific region or community. In contrast, a pandemic transcends borders, affecting people worldwide.
The impact of a pandemic goes beyond its immediate health consequences. It can disrupt economies, strain healthcare systems, and cause social upheaval. The COVID-19 pandemic serves as a stark reminder of how vulnerable our global society can be in the face of such crises.
A process server is a authorized person for delivering legal documents, such as summons, complaints, subpoenas, and other court papers, to peoples involved in legal proceedings.
Understanding the Challenges of Street ChildrenSERUDS INDIA
By raising awareness, providing support, advocating for change, and offering assistance to children in need, individuals can play a crucial role in improving the lives of street children and helping them realize their full potential
Donate Us
https://serudsindia.org/how-individuals-can-support-street-children-in-india/
#donatefororphan, #donateforhomelesschildren, #childeducation, #ngochildeducation, #donateforeducation, #donationforchildeducation, #sponsorforpoorchild, #sponsororphanage #sponsororphanchild, #donation, #education, #charity, #educationforchild, #seruds, #kurnool, #joyhome
ZGB - The Role of Generative AI in Government transformation.pdfSaeed Al Dhaheri
This keynote was presented during the the 7th edition of the UAE Hackathon 2024. It highlights the role of AI and Generative AI in addressing government transformation to achieve zero government bureaucracy
Many ways to support street children.pptxSERUDS INDIA
By raising awareness, providing support, advocating for change, and offering assistance to children in need, individuals can play a crucial role in improving the lives of street children and helping them realize their full potential
Donate Us
https://serudsindia.org/how-individuals-can-support-street-children-in-india/
#donatefororphan, #donateforhomelesschildren, #childeducation, #ngochildeducation, #donateforeducation, #donationforchildeducation, #sponsorforpoorchild, #sponsororphanage #sponsororphanchild, #donation, #education, #charity, #educationforchild, #seruds, #kurnool, #joyhome
Presentation by Jared Jageler, David Adler, Noelia Duchovny, and Evan Herrnstadt, analysts in CBO’s Microeconomic Studies and Health Analysis Divisions, at the Association of Environmental and Resource Economists Summer Conference.
What is the point of small housing associations.pptxPaul Smith
Given the small scale of housing associations and their relative high cost per home what is the point of them and how do we justify their continued existance
Canadian Immigration Tracker March 2024 - Key SlidesAndrew Griffith
Highlights
Permanent Residents decrease along with percentage of TR2PR decline to 52 percent of all Permanent Residents.
March asylum claim data not issued as of May 27 (unusually late). Irregular arrivals remain very small.
Study permit applications experiencing sharp decrease as a result of announced caps over 50 percent compared to February.
Citizenship numbers remain stable.
Slide 3 has the overall numbers and change.
2. Research Article
Responding to Health System Failure on Tuberculosis
in Southern Africa
Lauren Alecci Hartel1,
*, Abdo S. Yazbeck1
and Patrick L. Osewe2
1
International Development Division, Abt Associates, Rockville, MD, USA
2
Health Nutrition and Population Global Practice, World Bank, Washington, DC, USA
CONTENTS
Introduction
Methods
Results
Payment
Conclusion/Discussion
Note
References
Abstract—The characteristics of tuberculosis (TB)—such as links
to poverty, importance of patient actions, and prevalence of
multisectoral drivers—require more from health systems than
traditional medically oriented interventions. To combat TB
successfully, health systems must also address social risk factors
and behavior change in a multisector response. In this, many health
systems are failing. To explore why, and how they can do better, we
apply the Flagship Framework and its five “control knobs”
(financing, payment, organization, regulation, and behavior) to the
literature on TB control programs, focusing on the mining
population of Southern Africa, among whom the incidence of TB is
highest in the world. We conclude by recommending a patient-
centered approach that broadens a system’s engagement to a whole-
of–health sector, whole-of-government response.
INTRODUCTION
If treated immediately and effectively, tuberculosis (TB) has
a cure rate of over 90%.1
Despite this, it remains the number
two killer in the world—just barely outpaced by HIV/AIDS.2
After TB was classified as a disease by Robert Koch in 1882,
its first control programs focused on improved housing, ven-
tilation, and nutrition. These programs were successful in
lowering TB prevalence but gave way to medically oriented
interventions following the discovery of the bacillus Calm-
ette-Guerin vaccine in 1921 and treatments streptomycin in
1949 and isoniazid in 1951.3
Over decades, prevalence
declined steadily in middle- and high-income countries,
where improved socioeconomic conditions had the dual ben-
efit of supporting large-scale immunizations and improving
living conditions. In lower-income countries, where poverty,
overcrowding, and malnutrition continue, TB remains a large
problem. Moreover, recent spikes in TB prevalence—cata-
lyzed by HIV/AIDS—have remained largely impervious to
control efforts.
Keywords: health systems, mining, multisector, Southern Africa,
tuberculosis
Received 15 November 2017; revised 10 February 2018; accepted 10 February
2018.
*Correspondence to: Lauren Hartel; Email: lauren_hartel@abtassoc.com
Ó 2018 Lauren Alecci Hartel, Abdo S. Yazbeck, and Patrick L. Osewe.
This is an Open Access article distributed under the terms of the Creative
Commons Attribution License (http://creativecommons.org/licenses/by/4.0/),
which permits unrestricted use, distribution, and reproduction in any medium,
provided the original work is properly cited.
93
Health Systems Reform, 4(2):93–100, 2018
Published with license by Taylor Francis on behalf of the USAID’s Health Finance and Governance Project
ISSN: 2328-8604 print / 2328-8620 online
DOI: 10.1080/23288604.2018.1441621
3. With a high cure rate, a relatively inexpensive treatment,
and decades to refine treatment protocols, why has tuberculo-
sis been so persistent in these countries?
A look into the experience of the Southern African region
helps illuminate the factors that contribute to this ostensible
contradiction. In a region already fraught with poverty and
high levels of HIV, miners have the highest incidence of TB
in the world, at well over 2,000% the global average.a,4
They
fall victim to the heavy burden to complete lengthy treatment
regimens, the strong link to social determinants such as hous-
ing conditions and poverty, and the occupational risks that
make them simultaneously more likely to be infected with
TB and less likely to receive adequate care.
These barriers to effective treatment occur across the con-
tinuum of care and thus TB control programs must touch
every aspect of a nation’s health system to properly combat
them. For the purposes of this article, we use the World
Health Organization’s definition of “health systems” as a
system that “delivers quality services to all people, when and
where they need them” and does so through “a robust financ-
ing mechanism; a well-trained and adequately paid work-
force; reliable information on which to base decisions and
policies; well-maintained facilities and logistics to deliver
quality medicines and technologies.”5
Of course, it is natural for diseases of all types to prolifer-
ate more successfully in areas where health systems are inad-
equate—this is the rationale underpinning most advocacy for
health systems strengthening.6
The purpose of our article,
however, is not to emphasize the connection between health
systems and better disease outcomes. Rather, it is to encour-
age health systems to grow and adapt beyond their traditional
approach to deliver a whole-of–health sector, whole-of-gov-
ernment, even whole-of-region response.
METHODS
To explore why health systems are failing to combat TB in
Southern Africa and how they can do better, we synthesized
the large body of published literature on TB and health sys-
tems in a systematic way. We structured the literature review
around the Flagship Framework,7
The Framework revolves
around five actionable and interrelated health sector policy
areas, termed “control knobs.” These knobs—financing, pay-
ment, organization, regulation, and behavior—can be used in
combination to influence intermediate outcomes such as effi-
ciency, quality, and access, in order to impact health system
outputs (Figure 1).
In the literature search, we used keywords such as
“tuberculosis,” “TB,” and “Southern Africa,” in conjunc-
tion with each of the five control knobs, as search terms to
retrieve relevant articles. Only articles published in the last
20 years and in English were included in the review.
In addition, two of the authors drew from direct experi-
ence between 2013 and 2016, when the World Bank worked
with the government of South Africa, the World Health
Organization (WHO), the United States Agency for Interna-
tional Development, and other partners to better understand
the challenges faced by the government in tackling TB in
mining industry. This included two meetings bringing
together local and international experts: February 8–9, 2015,
in Cape Town and October 1–4, 2014, in Pretoria. Partici-
pants included representatives of the Global Fund to Fight
AIDS, Tuberculosis, and Malaria; the World Health Organi-
zation; the United States Agency for International Devel-
opment’s Office of Infectious Disease, within the Bureau for
Global Health; the World Bank Southern Africa team; and
the Stop TB Partnership. From within the region, experts
included Ministry of Health officials from South Africa, uni-
versity professors from Cape Town University and the Uni-
versity of Witswatersrand, private-sector members for
service delivery and health insurance, ex-mine workers, and
labor recruitment for the mining sector.
RESULTS
In the following section, we review the results of our
research, first reviewing the challenges that TB presents to
health systems, honing in on the challenges most prevalent
for Southern African miners and finally highlighting each
“control knob.” Where evidence allows, we present examples
of how these knobs impact TB control programs and recom-
mend ways to turn the knobs toward a more effective,
patient-centered approach.
Tuberculosis and Health Systems
Tuberculosis requires a proactive and targeted approach to
finding cases, yet those most vulnerable to exposure can also
be the hardest to reach. Once diagnosed, they face lengthy
direct observation treatment–short course therapy, which
lasts between six and nine months, and must be observed for
the first two months (or more). Patients frequently discon-
tinue this because taking time off work or making long trips
to the nearest TB provider is difficult.3
Still others are not
educated about the importance of completing their entire reg-
imen and so stop treatment when their symptoms cease
because they believe they are cured.
These factors can propagate multiple-drug-resistant
(MDR) tuberculosis, a deadly strain that only 52% of patients
overcome.8
Treatment for MDR TB can easily overwhelm
94 Health Systems Reform, Vol. 4 (2018), No. 2
4. health budgets of middle- and low-income countries, where
95% of cases occur.9
In these instances, what might have
started as a relatively manageable case of TB can quickly
grow into a widespread epidemic, exacerbating the health
system failures that allowed TB to thrive in the first place.
The struggle certain countries face in effectively com-
batting TB illustrates just how clearly TB links to the capa-
bilities of health systems. However, this is not a lens through
which TB is historically viewed. Te WHO’s strategy has tra-
ditionally focused on how TB presents in the population.10,11
Though this approach effectively highlights countries that
have the highest estimated numbers of TB cases and high-
lights the similarities TB can have across the globe, it does
not capture the underlying drivers that cause TB to surface in
the first place and persist so doggedly. Socioeconomic factors
such as occupation, poor housing conditions, and existing
comorbidities are stronger predictors of TB case notification
trends than is national TB program performance.11,12
In fact,
empirical analysis has demonstrated that the WHO’s TB con-
trol interventions alone have not helped bend the curve of TB
incidence.13
More recently, attention has been given to the importance
of underlying social and economic structures in the last
decade. In the transition from the Millennium Development
Goals (2005–2015) to the Sustainable Development Goals
(launched in 2015), the WHO asserted that Goal Three is to
“ensure healthy lives,” but almost all of its eight goals affect
health outcomes.14
Studies have similarly broadened to
examine social factors such as cultural norms. For example,
treatment default on direct observation treatment–short
course therapy was revealed to be directly linked to conflict-
ing cultural norms in the state of Gujarat in India in 2014,
where dietary recommendations challenged patients’ vege-
tarian traditions.15
The WHO has also begun emphasizing
the importance of social factors: 2017 marks the second year
of a new Unite to End TB campaign, espousing “a whole-of-
society and multidisciplinary approach.”16
Examining the Case of Miners in Southern Africa
The Southern African region—consisting of Angola, Bot-
swana, Lesotho, Malawi, Mozambique, Namibia, South
Africa, Swaziland, Zambia, and Zimbabwe—has the highest
TB incidence in the world. Ranging from 10% in Malawi to
27% in Lesotho and Botswana, these countries consistently
top global rankings of TB in both absolute numbers and in
cases per capita.17,18
Though some progress has been made,
with increased numbers of patients receiving treatment and
higher case detection rates, overall incidence remains stag-
nant. There are many reasons for this, but few are as influen-
tial as pervasive poverty, high rates of HIV/AIDS, and
occupational risks of the mining industry.
For countries with limited resources, reaching vulnera-
ble populations is exceedingly difficult: in Mozambique,
the case detection rate hovers around a mere 38% of the
population.10,19
For the region, TB/HIV coinfections are
higher than anywhere else in the world: in Botswana,
between 60% and 86% of TB patients also live with
HIV; in Lesotho this hovers around 64%.10,20,21
As a
result, the majority of TB diagnoses and treatment serv-
ices in the region are viewed through an HIV lens.22
When done properly, HIV/TB program integration is a
positive and essential part of effectively treating TB—
however, fatalities remain unacceptably high.23
Addition-
ally, such programming can be imbalanced: for every 100
USD that the Global Fund spends in sub-Saharan Africa,
for example, only $6 goes to TB programming.4
These factors converge in the case of miners. Botswana,
South Africa, Zambia, and Zimbabwe all rely economically
on the vitality of their mines, as do Lesotho and Malawi indi-
rectly due to their status as labor-exporting countries.17
Unfortunately, a combination of occupational and demo-
graphic traits, including poor ventilation, indoor pollution,
FIGURE 1. The Role of the Control Knobs in Health Sector
Reform
Hartel et al.: Responding to Health System Failure on Tuberculosis in Southern Africa 95
5. and high population density, increases the miners’ risks of
being exposed to TB. Once exposed, several demographics
compound their chances of being actively infected: poverty,
malnourishment, active smoking, and/or frequent use of alco-
hol. These risk factors are worsened by the high prevalence
of TB already present in the mining community.12
It is estimated that in South Africa alone, implementing
activities to tackle TB would result in increased mining produc-
tivity worth 783 million USD per year.4
That the country has
not acted to mitigate risks to miners despite such potential gains
speaks to the challenges of implementing an adaptable, multi-
sectoral response. Where exactly these challenges lie and how
a system can change them are described in the next section.
What Can Be Done Differently
When a health system does grow and adapt to include social,
multisectoral responses, TB control programs struggle to
work effectively. In illustrating this, we organize our results
in this section using the Flagship Framework’s five control
knobs. When applicable, we highlight the broader social
determinants or drivers that remain unaddressed and the need
to turn the knobs in a way that increases the multisectoral
nature and adaptability of the health sector in tackling TB.
Financing
There is overwhelming evidence of the links between pov-
erty and limited access to TB services, including the impact
of financial barriers to access.24-27
These barriers manifest
directly in the costs of goods and services. They also include
the opportunity costs that patients must incur in the time they
take to seek screening and treatment, which can result in lost
income both immediately and potentially in the future if they
miss too much work and lose their job.
Financial barriers to accessing care can be eliminated in
various ways. Most countries in Southern Africa attempt to
eliminate fees for TB services or, alternatively, implement tar-
geted exemption mechanisms for poor or highly vulnerable
populations.28
Despite free treatment, many TB patients still
face catastrophic costs that limit their access to care: despite
having free TB treatment in South Africa, the average time
between experiencing symptoms and receiving a TB test jumps
from 33 days to 90 when comparing the poorest group to the
less-poor group.29
In addition to delaying treatment—which
gives the disease in the larger population more time to develop
drug resistance—the extra days also triple the time that fami-
lies, coworkers, and others in the community are exposed.
Additional financing policy interventions, such as condi-
tional cash transfers or voucher mechanisms, must be
considered. These work through demand-side financing and
also relate to other control knobs such as payment (to pro-
viders) and behavior changes. There is increasing evidence
of the success of cash transfers in tackling inequality in
access to care by allowing households to break the cycle of
poverty through addressing many of these indirect costs head
on, such as improving ventilation in their homes or using
public transportation to cover long distances to facilities
more quickly.12,28,30
Research conducted in Malawi with
HIV/AIDS, for example, revealed that even relatively small
monetary incentives encouraged uptake of interventions and
changed people’s health-seeking behaviors by compensating
for economic and psychological costs of HIV testing.31
PAYMENT
Incentives, or Disincentives, Created by Paying Providers
through Various Mechanisms
Effective TB prevention and treatment is dependent upon
expansive case finding for both drug-sensitive and drug-resis-
tant strains and high patient adherence for both drug-sensitive
TB and MDR TB treatments. For both of these important
objectives, provider payment–based incentives can increase
the likelihood of success. Instruments such as results-based
financing can be used to improve performance of both public
and private providers for diagnosis and treatment of TB. Diag-
nosis-related group payment mechanisms, for example, did
this for hospitals in the former Soviet Union.32
The limited nature of evidence directly linking results-based
payments to health outcomes prevents us from making full-
fledged recommendations in this area.33
However, the experi-
ences of other countries when challenged by payments may
offer lessons to Southern Africa on what to avoid. In China,
provider payment mechanisms are having unintended conse-
quences, derailing the effectiveness of a recently instituted pol-
icy of free treatment for TB. Because facilities cannot charge
for TB services directly but can charge for repeated and/or
ancillary tests, they frequently will provide additional, unnec-
essary services for which they can be paid. Primary clinics
there also will delay patient referrals to hospitals that provide
TB services. As a result, patients receive delayed diagnoses
and experience gaps between diagnosis and treatment, as well
as incur costs for possibly inappropriate testing.34
Organization
Historical inequities in South Africa’s public health system,
coupled with the extent of the combined TB and HIV epi-
demics within the region, have created enormous operational
96 Health Systems Reform, Vol. 4 (2018), No. 2
6. challenges for integrated health service delivery.4,35-37
A
decades-long legacy of disease-specific vertical program-
ming, particularly for TB and HIV, resulted in fragmented,
poorly coordinated care. Prior to the country’s integrated
response to TB and HIV in 2010, services were delivered by
different staff and often located in separate clinics, hindering
communication between managers and exacerbating ineffi-
ciencies in joint planning.38
Furthermore, weak communica-
tion among the national, provincial, and district levels in the
South African health system resulted in poor integration of
program management at provincial and district levels. Such
challenges can be insurmountable for mine workers with TB,
and limited access to primary care doctors, a deficient refer-
ral system, and gaps in follow-up have led many to discon-
tinue treatment.39
This fragmentation is exacerbated by high volumes of
migrants: almost half of the workers in South African mines
are migrants from Lesotho, Mozambique, and Swaziland.40
Migrants are not unique to Southern Africa, but circumstan-
ces are particularly challenging in this region, where no com-
mon language is spoken across countries. In Zambia,
Namibia, and Mozambique alone, more than a hundred lan-
guages are spoken (32, 28, and 41, respectively).17
A step in the right direction is efforts to harmonize TB
treatment protocols across the Southern Africa region and to
evolve a regional response through the political structure of
SADC, the Southern Africa Development Cooperation mech-
anism.4
In South Africa specifically, there have been promis-
ing efforts to strengthen the health system and ensure
affordable, effective, and quality health services—most nota-
bly through primary health care re-engineering and phased
implementation of national health insurance.41
Most
recently, the World Bank has launched a 122 million USD
program aimed at controlling TB in Southern Africa by
focusing on mining communities, regions with high HIV/
AIDS comorbidities, transport corridors, and cross-border
areas of Lesotho, Malawi, Mozambique, and Zambia.18
Regulation
Setting the rules of the health care game and ensuring
that somebody is accountable for enforcing them is a crit-
ical function of government. Mechanisms include control
regulation (using the mandating instruments of govern-
ment), incentive regulation (using payment systems to
create incentives for provider behavior), or self-regulation
(building and strengthening professional organizations
and empowering them to influence provider behavior).
Fragmentation in the service delivery for TB complicates
regulatory functions.
Lax regulation contributes to the proliferation of TB in
Zambia. Mines there have an average total of respirable dust
concentrations that is well above the limit recommended by
safety authorities yet can operate because levels are still
below the legal limit enforced by the Zambian government.42
Another example is easily found in South Africa, whose min-
ing sector is regulated by its Department of Minerals rather
than its Department of Health. As a result, despite TB’s sky-
high prevalence among miners, regular screenings of TB are
not implemented widely, and there are few programs in place
to educate miners about the occupational risks they are tak-
ing and their vulnerability to acquiring TB. In 2010, the
South African National Institute for Occupational Health sur-
veyed 63 mines and found that only 40% provided TB serv-
ices on site.40
For the many miners who are not permanent employees
but contracted or completely informal workers, these oppor-
tunities are even fewer. Moreover, absence of job security
and/or occupational disease compensation creates strong dis-
incentives for workers to take advantage of screenings in the
few places they are offered for fear of losing needed income.
The growing number of undocumented migrant workers
across the region are even more vulnerable to being abused
in this environment of lax regulation.40
A successful regula-
tory response to TB requires a health system to be flexible in
bringing other sectors on board for preventive and care serv-
ices but also requires national leadership to facilitate multi-
sector responsibilities and actions.43
Behavior
In the context of TB in Southern Africa, central issues relate
to on-the-job-related prevention activities for miners, report-
ing illness despite the risk of losing their job, and compliance
with the full medication regimen once diagnosed. Disincen-
tives to health-seeking behavior are alive and well. In Zam-
bia, for example, not only are miners infected with TB
removed from the mines but prospective miners found to test
positive for TB prior to employment may not work.42
This
can create distrust between the mining institution and the
miners. The social and historic context of poverty, low edu-
cation, and a legacy of racism in the mining sector make
changing this policy especially difficult.22
Interventions should revolve around finding and strength-
ening community-based information and support mecha-
nisms that respond to distrust of institutions, as well as using
incentive-targeted mechanisms such as conditional cash
transfers and vouchers. Utilizing trusted channels, such as
ex-mine workers and ex-mine worker associations, as part of
community outreach or as community health workers has the
Hartel et al.: Responding to Health System Failure on Tuberculosis in Southern Africa 97
7. potential to improve health-seeking behaviors and adherence
to TB treatment protocols.39
CONCLUSION/DISCUSSION
TB in Southern Africa continues to be an unfortunate fact of
life and death for its 65 million inhabitants. The nature of the
disease, the link to poverty and vulnerability connected to a
history of racism around mining and civil rights, and the
complications of multisectorality and cross-country migra-
tion and coordination are among the reasons for this failure
of the health sector. Clearly, business as usual is not solving
this challenge. Here we identify needs and propose certain
concrete steps, some already under way, in recognition of the
need for the health sector be more resilient and to expand its
toolkit beyond funding and service delivery to include influ-
ence, empowerment, and broad stewardship.
A central dimension of addressing TB in Southern Africa
is the need to explore and address population-based and pop-
ulation-focused issues and challenges. The disproportionate
prevalence of TB among socioeconomically vulnerable pop-
ulations such as migrant miners makes it critical to take a
community-based response and to ensure that services are
patient centered and take into account how the population
receives and acts on life-saving information. Some of that
work is already beginning in the region, with authorities
reaching out to miners through trusted channels (e.g., by
employing nongovernmental groups such as ex-mine work-
ers from the same labor-sending regions and speaking the
same language).
Second, TB control efforts in Southern Africa should con-
tinue to acknowledge the multisectoral drivers of the disease
highlighted by the mining industry and advocate more
strongly with non-health-sector actors. The dominant sectors
that can regulate economic activities that in turn influence
the drivers of TB are the departments of minerals, labor, and
migration, and not health. This means that a successful
response to TB in Southern Africa has to be a whole-of-gov-
ernment approach, in which the health sector plays a coordi-
nating and empowering role.
Finally, a regional approach is necessary to account for the
Southern Africa cross-border challenge linked largely to
migration of mining workers. The implication is that an effec-
tive response to TB in Southern Africa requires a regional
approach. An excellent example is a recent effort to harmo-
nize TB treatment protocols across the region and to evolve a
regional response through the political structure of SADC.4
It is heartening to see that recent efforts to tackle TB in
Southern Africa have gone beyond the basic medical approach.
Though clear cost-effective medical approaches exist, the
challenge is beyond basic delivery and financing of services.
New efforts have begun to put the population first and pay
attention to what motivates them to change their behavior.
These efforts are also focused on strengthening collaboration
across the different parts of the health sector (whole-of-sector
approach), across sectors to work more closely with Minerals
and Labor (whole-of-government approach), and across
national borders (whole-of-region approach).
To reverse centuries of system failure, however, collective
efforts need to be sustained and even expanded, and the
health sector needs to show a higher level of resilience than
it has to date.
NOTE
a. Miners in South Africa, for example, have a TB inci-
dence rate between 3,000 and 7,000 per 100,000 com-
pared to the global incidence of 128 per 100,000.
DISCLOSURE OF POTENTIAL CONFLICTS
OF INTEREST
The authors report no conflict of interest.
FUNDING
This manuscript was funded by the U.S. Agency for Interna-
tional Development (USAID) as part of the Health Finance
and Governance project (2012-2018), a global project work-
ing to address some of the greatest challenges facing health
systems today. The project is led by Abt Associates in collab-
oration with Avenir Health, Broad Branch Associates, Devel-
opment Alternatives Inc., the Johns Hopkins Bloomberg
School of Public Health, Results for Development Institute,
RTI International, and Training Resources Group, Inc. This
material is based upon work supported by the United States
Agency for International Development under cooperative
agreement AID-OAA-A-12-00080. The contents are the
responsibility of the authors and do not necessarily reflect the
views of USAID or the United States Government.
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