: A Research design is a logical and systemic plan prepared for directing research. It specifies the objectives of the study, the methodology and techniques to be adopted for achieving the objectives. It constitutes the blue print for the collection, measurement and analysis of data. It is the plan, structure and strategy of investigation conceived so as to obtain answers to research questions. A research design is the program that guides the investigator in the process of collecting, analyzing and interpreting observations.
The research approach indicates the basic procedure for conducting research.
Research approach is the technique which the researcher uses to structure a study in order to gather and analyze information relevant to the research question .
The research approach indicates the basic procedure for conducting research.
Research approach is the technique which the researcher uses to structure a study in order to gather and analyze information relevant to the research question .
In observational studies, a researcher merely documents the presence of exposure(s) and outcome(s) as they occur, without trying to alter the course of natural events. By contrast, in interventional studies, the researcher actively interferes with nature – by performing an intervention in some or all study participants – to determine the effect of exposure to the intervention on the natural course of events. An example would be a study in which the investigator randomly assigns the participants to receive either aspirin or a placebo for a specific duration to determine whether the drug has an effect on the future risk of developing cerebrovascular events. In this example, aspirin (the “intervention”) is the “exposure,” and the risk of cerebrovascular events is the “outcome.” Interventional studies in humans are also commonly referred to as “trials.”
Interventional studies, by their very design, are prospective. This sometimes leads to confusion between interventional and prospective cohort study designs. For instance, the study design in the above example appears analogous to that of a prospective cohort study in which people attending a wellness clinic are asked whether they take aspirin regularly and then followed for a few years for occurrence of cerebrovascular events. The basic difference is that in the interventional study, it is the investigators who assign each person to take or not to take aspirin, whereas in the cohort study, this is determined by an extraneous factor.
Interventional studies can be divided broadly into two main types: (i) “controlled clinical trials” (or simply “clinical trials” or “trials”), in which individuals are assigned to one of two or more competing interventions, and (ii) “community trials” (or field trials), in which entire groups, e.g., villages, neighbourhoods, schools or districts, are assigned to different interventions.
The interventions can be quite varied; examples include administration of a drug or vaccine or dietary supplement, performance of a diagnostic or therapeutic procedure, and introduction of an educational tool. Depending on whether the intervention is aimed at preventing the occurrence of a disease (e.g., administration of a vaccine, boiling of water, distribution of condoms or of an educational pamphlet) or at providing relief to or curing patients with a disease (e.g., antiretroviral drugs in HIV-infected persons), a trial may also be referred to as “preventive trial” or “therapeutic trial”.
VARIOUS TYPES OF INTERVENTIONAL STUDY DESIGNS
Several variations of interventional study designs with varying complexity are possible, and each of these is described below. Of these, the most commonly used and possibly the strongest design is a randomized controlled trial (RCT).
Randomized controlled trials
In an RCT, a group of participants fulfilling certain inclusion and exclusion criteria is “randomly” assigned to two separate groups, each receiving a different intervention. Random assignme
WHAT IS METHODOLOGY?
WHAT IS RESEARCH?
WHAT IS RESEARCH METHODOLOGY?
STUDY DESIGNS
WHAT IS DESCRIPTIVE STUDY?
WHAT IS ANALYTICAL STUDY?
CONCLUSION
REFERENCES
The need for good research is to find the best evidence for clinical
practice, for specific problems, and to address methods in reducing the
burden of illness on a larger scale.
It should reflect the aspirations and expectations of the research topic.
The slides will help you in knowing the components of research design in brief what is research design, components of research design, differnt types of research design
Ain al-Hayat: This is the dedicated treatise on the subject of Geriatrics and Gerontology, authored by Mohammad Ibn Yusuf Al-Harawi around 1532 AD. The fundamentals of this treatise are based on the humoral theory of medicine. According to this doctrine, every organism gets a fixed amount of innate moisture from its parent at the time of conception that is utilized for the survival of life. Innate heat is retained in innate moisture that is used as a fuel for life. With the increase in age, the amount of innate moisture gradually decreases and ultimately becomes insufficient to maintain life leading to the death of an organism. This book is based on three objectives:
1. Theory of aging based on innate heat and moisture,
2. Description of drugs and regimens that strengthen the innate heat.
3. Description of drugs and regimens that weakens the innate heat.
• This treatise discusses upon following:
• Number of single drugs mentioned: 87
• Number of compound drugs mentioned: 10
• Name of compound drugs mentioned: Anushdaru, Barshasha, Tiryaq Kabir, Julab, Janjabeen, Khamar, Ghalia, Faloojaz, Maa ul leham, and mussalas.
• Number of regimens: 04
• Asbab e sitta zarooriya (six essentials of life): Authored has a core focus on maintaining a healthy harmony among the six essentials of life.
• Habitats, Habit, and Manners: High altitude residence, tour and journey, Hunting, Music, Intimacy, intercourse, lovemaking, and admiration
There are four Persian manuscripts of this treatise available. One copy is at the State oriental manuscript library and Research Institute, Hyderabad, one copy is at Raza Library, Rampur, and two copy at the Ibn Sina Academy of Medieval Medicine and Sciences in Aligarh.
This treatise was translated into Urdu by prof S. Zillur Rahmanin 2007 and English by Ashfaque Ahmad IN 2019
Urdu translator: Hakim Syed Zillur Rahman, Professor, at the Ajmal Khan Tibbiya College, AMU, Aligarh. He was honored with Padma Shri in 2006 by the Government of India for his contribution to the field of medicine. He is the founder of Ibn Sina Academy of Medieval Medicine and Sciences, Aligarh.
English Translator: Ashfaque Ahmad, Research Officer at CCRAS- National Institute of Indian Medical Heritage, Hyderabad translated this treatise into English.
Author: The author of Ain al-Hayat, Mohammad Ibn Yousuf Al-Harwi was a Persian-born, Indian medical scholar of the 16th century. He also authored the Bahrul Jawaha, a medical dictionary. He came to India with emperor Babur in 1526 after the first war of Panipath. Yousuf Al-Harwi died in 1544 in India.
Jan Jan Unani is a Health Care Program to control and prevent non-communicable diseases . This program is organized by AUP Bihar. This training booklet is developed for taring of doctors participating in this program.
In observational studies, a researcher merely documents the presence of exposure(s) and outcome(s) as they occur, without trying to alter the course of natural events. By contrast, in interventional studies, the researcher actively interferes with nature – by performing an intervention in some or all study participants – to determine the effect of exposure to the intervention on the natural course of events. An example would be a study in which the investigator randomly assigns the participants to receive either aspirin or a placebo for a specific duration to determine whether the drug has an effect on the future risk of developing cerebrovascular events. In this example, aspirin (the “intervention”) is the “exposure,” and the risk of cerebrovascular events is the “outcome.” Interventional studies in humans are also commonly referred to as “trials.”
Interventional studies, by their very design, are prospective. This sometimes leads to confusion between interventional and prospective cohort study designs. For instance, the study design in the above example appears analogous to that of a prospective cohort study in which people attending a wellness clinic are asked whether they take aspirin regularly and then followed for a few years for occurrence of cerebrovascular events. The basic difference is that in the interventional study, it is the investigators who assign each person to take or not to take aspirin, whereas in the cohort study, this is determined by an extraneous factor.
Interventional studies can be divided broadly into two main types: (i) “controlled clinical trials” (or simply “clinical trials” or “trials”), in which individuals are assigned to one of two or more competing interventions, and (ii) “community trials” (or field trials), in which entire groups, e.g., villages, neighbourhoods, schools or districts, are assigned to different interventions.
The interventions can be quite varied; examples include administration of a drug or vaccine or dietary supplement, performance of a diagnostic or therapeutic procedure, and introduction of an educational tool. Depending on whether the intervention is aimed at preventing the occurrence of a disease (e.g., administration of a vaccine, boiling of water, distribution of condoms or of an educational pamphlet) or at providing relief to or curing patients with a disease (e.g., antiretroviral drugs in HIV-infected persons), a trial may also be referred to as “preventive trial” or “therapeutic trial”.
VARIOUS TYPES OF INTERVENTIONAL STUDY DESIGNS
Several variations of interventional study designs with varying complexity are possible, and each of these is described below. Of these, the most commonly used and possibly the strongest design is a randomized controlled trial (RCT).
Randomized controlled trials
In an RCT, a group of participants fulfilling certain inclusion and exclusion criteria is “randomly” assigned to two separate groups, each receiving a different intervention. Random assignme
WHAT IS METHODOLOGY?
WHAT IS RESEARCH?
WHAT IS RESEARCH METHODOLOGY?
STUDY DESIGNS
WHAT IS DESCRIPTIVE STUDY?
WHAT IS ANALYTICAL STUDY?
CONCLUSION
REFERENCES
The need for good research is to find the best evidence for clinical
practice, for specific problems, and to address methods in reducing the
burden of illness on a larger scale.
It should reflect the aspirations and expectations of the research topic.
The slides will help you in knowing the components of research design in brief what is research design, components of research design, differnt types of research design
Ain al-Hayat: This is the dedicated treatise on the subject of Geriatrics and Gerontology, authored by Mohammad Ibn Yusuf Al-Harawi around 1532 AD. The fundamentals of this treatise are based on the humoral theory of medicine. According to this doctrine, every organism gets a fixed amount of innate moisture from its parent at the time of conception that is utilized for the survival of life. Innate heat is retained in innate moisture that is used as a fuel for life. With the increase in age, the amount of innate moisture gradually decreases and ultimately becomes insufficient to maintain life leading to the death of an organism. This book is based on three objectives:
1. Theory of aging based on innate heat and moisture,
2. Description of drugs and regimens that strengthen the innate heat.
3. Description of drugs and regimens that weakens the innate heat.
• This treatise discusses upon following:
• Number of single drugs mentioned: 87
• Number of compound drugs mentioned: 10
• Name of compound drugs mentioned: Anushdaru, Barshasha, Tiryaq Kabir, Julab, Janjabeen, Khamar, Ghalia, Faloojaz, Maa ul leham, and mussalas.
• Number of regimens: 04
• Asbab e sitta zarooriya (six essentials of life): Authored has a core focus on maintaining a healthy harmony among the six essentials of life.
• Habitats, Habit, and Manners: High altitude residence, tour and journey, Hunting, Music, Intimacy, intercourse, lovemaking, and admiration
There are four Persian manuscripts of this treatise available. One copy is at the State oriental manuscript library and Research Institute, Hyderabad, one copy is at Raza Library, Rampur, and two copy at the Ibn Sina Academy of Medieval Medicine and Sciences in Aligarh.
This treatise was translated into Urdu by prof S. Zillur Rahmanin 2007 and English by Ashfaque Ahmad IN 2019
Urdu translator: Hakim Syed Zillur Rahman, Professor, at the Ajmal Khan Tibbiya College, AMU, Aligarh. He was honored with Padma Shri in 2006 by the Government of India for his contribution to the field of medicine. He is the founder of Ibn Sina Academy of Medieval Medicine and Sciences, Aligarh.
English Translator: Ashfaque Ahmad, Research Officer at CCRAS- National Institute of Indian Medical Heritage, Hyderabad translated this treatise into English.
Author: The author of Ain al-Hayat, Mohammad Ibn Yousuf Al-Harwi was a Persian-born, Indian medical scholar of the 16th century. He also authored the Bahrul Jawaha, a medical dictionary. He came to India with emperor Babur in 1526 after the first war of Panipath. Yousuf Al-Harwi died in 1544 in India.
Jan Jan Unani is a Health Care Program to control and prevent non-communicable diseases . This program is organized by AUP Bihar. This training booklet is developed for taring of doctors participating in this program.
Kitab Al-Hawi (Liber Continens), a compilation of his readings of Greek and Roman medicine, his own clinical observations and case studies, and methods of treatment during his years of medical practice. It is generally thought that this book was compiled by his students after his death. It was translated in 1279 to Latin by Faraj Ibn Salim, a scholar working at the Court of the king of Sicily. The first Latin edition of the “Continens”, published at Brescia, Italy, in 1486, is the largest and heaviest book printed before 1501. This book was considered the most significant medical book in the medieval ages. The fame of Al Razi as one of the greatest Muslim physicians is mainly due to the case records and histories written in this book.
This is Urdu translation of Al Hawi of Razi by CCIM.
Al-Hawi or Kitāb al-Ḥāwī fī al-ṭibb translated as The Comprehensive Book on Medicine is a medical composition authored by Rhazes in the 10th century. It was first translated into Latin in 1279 under the title Continens by Faraj ben Salīm, a physician of Sicilian-Jewish origin employed by Charles of Anjou.
The Virtuous Life (al-Hawi الحاوي).
This monumental medical encyclopedia in nine volumes—known in Europe also as The Large Comprehensive or Continens Liber (جامع الكبير)—contains considerations and criticism on the Greek philosophers Aristotle and Plato, and expresses innovative views on many subjects.[37][38][39] Because of this book alone, many scholars consider al-Razi the greatest medical doctor of the Middle Ages.
Kitāb al-hāḳī (“Comprehensive Book”), but whose most famous work, De variolis et morbillis (A Treatise on the Smallpox and Measles), distinguishes between these two diseases and gives a clear description of both.
Hawi or Kitāb al-Ḥāwī fī al-ṭibb translated as The Comprehensive Book on Medicine is a medical composition authored by Rhazes in the 10th century. It was first translated into Latin in 1279 under the title Continens by Faraj ben Salīm, a physician of Sicilian-Jewish origin employed by Charles of Anj. This is urdu translation by CCIM
A report
submitted by five members
committee lead by
Dr. Shabistan Fatma Taiyabi,
to understand the present
status and its remedy of the
Unani System of Medicine in
Bihar, Jharkhand, and
West Bengal.
The Gale Encyclopedia of Diets: A Guide to Health and Nutrition is a health reference product designed to inform and educate readers about a wide variety of
diets, nutrition and dietary practices, and diseases and
conditions associated with nutrition choices. The Gale
Group believes the product to be comprehensive, but not necessarily definitive. It is intended to supplement, not replace, consultation with a physician or other healthcare practitioners
The employment opportunity in any field of education is directly proportional to
its growth and development. The Unani medicine is an ancient system and an integral part of
indigenous medicine in India. The population of Bihar increase five-fold from its establishment,
but not a single Government Unani medical college has been established for a long duration of
75 years since independence. Whereas first Homeopathic College of Bihar, RBTS, Muzaffarpur
was established in 1958 and was undertaken by the Government of Bihar on 1st April 1981.
Homeopathy achieves accelerated growth in the previous three decades due to its second-highest
allocated quota (30%) in government employment. In the recent past, the Homeopathic Doctors
Association, BSHMOA, Patna, made a mendacious statement that the existing allocated quota
among the different streams of AYUSH is based on the number of admission of students and the
number of registered doctors in the respective stream in the state. In this mendacious statement,
they were attempting to reach an irrational conclusion but they did not thrive in this. The fact
concerning this event are being systematically summaries in this Pdf.
This book is on poem of medicine published by Dafatre Madsihi. the Dafatre Madsihi was a publishing house of Tibbi books that was established by Hkm. Mohd. Kabiruddin.
डा.शबिस्ता फातमा तय्यबी
यूनानी भारत की देशी चिकित्सा पद्धति है। इस विज्ञान की उत्पत्ति ढ़ाई हजार वर्ष पूर्व ग्रीक सभ्यता के स्वर्णिम काल में हुआ था ।
यूनानी चिकित्सा विज्ञान, चिकित्सा विज्ञान के जनक Hippocrates के अखलात के सिद्धांत पर आधारित है। इस सिद्धांत के अनुसार शरीर में चार प्रकार के अखलत होता है, जो स्वस्थ्य अथवा बीमारी के लिए उत्तरदायी होता है।
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
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These lecture slides, by Dr Sidra Arshad, offer a quick overview of the physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
10. Define the mean QRS vector
11. Describe the axes of leads (hexagonal reference system)
12. Comprehend the vectorial analysis of the normal ECG
13. Determine the mean electrical axis of the ventricular QRS and appreciate the mean axis deviation
14. Explain the concepts of current of injury, J point, and their significance
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. Chapter 3, Cardiology Explained, https://www.ncbi.nlm.nih.gov/books/NBK2214/
7. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
1. 1
ASSIGNMENT
Index
▪ Research Design (Page 2 to 5)
▪ Introduction
▪ Need of Research Design
▪ Characteristics of a good Research Design
▪ Component of Research Design
▪ Different type of Research Design
▪ Sampling ( Page 6 to 9)
▪ Purpose of sampling
▪ Advantage of sampling
▪ Characteristics of a good sample
▪ Types of sampling
2. 2
ASSIGNMENT
Research Design
Introduction: A Research design is a logical and systemic plan prepared for directing research. It
specifies the objectives of the study, the methodology and techniques to be adopted for achieving
the objectives. It constitutes the blue print for the collection, measurement and analysis of data. It
is the plan, structure and strategy of investigation conceived so as to obtain answers to research
questions. Aresearch design is the program that guides the investigator in the process of collecting,
analyzing and interpreting observations.
Needs of Research Design
a. Many a research enquiry, the researcher has no idea as to how accurate the results of his /her
study ought to be useful, where such in the case, the researcher has to determine how much
inaccuracy may be tolerated.
b. In many research projects, the time consumed in trying to ascertain what the data mean after
they have been collected is much greater than the time taken to design research which yields data
whose meaning is known as they are collected.
c. The idealized design is concerned with specifying the optimum research procedure that could
be followed were there no practical restrictions.
Characteristics of a Good Research Design
a. It is a series of guide post to keep one going in the right direction.
b. It reduces wastage of time and cost.
c. It encourages co-ordination and effective organization.
d. It is a tentative plan which undergo modifications, as circumstances demand, when the study
progresses, new aspects, new conditions, and new relationships come to light and insight into the
study deepens.
e. It has to be geared to the availability of data and the cooperation of the informants.
f. It has also to be kept within the manageable limits.
3. 3
ASSIGNMENT
Components of Research Design
It is important to be familiar with the important concepts relating to research design. They are:
1. Dependent and Independent variables: A magnitude that varies is known as variable. When
changes in one variable depends upon the changes in one or more other variables, it is
known as a dependent or endogenous variable, and the variables that cause the changes in
the dependent variable are known as the independent or exogenous variables.
2. Extraneous variable: The independent variable which are not directly associated to the
purpose but effect the dependent variable are known as extraneous variable.
3. Control: One of the most important features of a good research design is to minimize the
effect of extraneous variable. Technically, the term control is used when a researcher
designs the study in such a manner that it minimizes the effect of extraneous independent
variables. The term control is used in experimental research to reflect the restrain in
experimental conditions.
4. Confounded relationship: The relationship between dependent and independent variables
is said to be confounded by an extraneous variable, when the dependent variable is not
from its effect.
5. Research hypothesis: It is the predictive statement which relates a dependent variable and
an independent variable.
6. Control group: In experimental research, the group which is exposed to usual condition is
known as control group.
7. Experimental group: The group which is either receive or exposed to the intervention is
called experimental group.
8. Treatment: It is referred to the different condition to which the experimental and control
group is subjected to.
Different type of research design:
1. Experimental Research Design: It is the most scientifically sophisticated research
method. Experimental research designs are concerned with examination of the effect of
the independent variable on the dependent variable, where the independent variable is
4. 4
ASSIGNMENT
manipulated through treatment or intervention, and the effect of these interventions is
observed on the dependent variable. It is the process of carrying out research in an
objective and controlled fashion so that precision is maximized and specific conclusions
can be drawn regarding a hypothesis statement. Generally, the purpose is to establish the
effect that a factor or independent variable has on a dependent variable.
Three main characteristics of experimental research design:
a. Manipulation: It refers to a conscious control of the independent variable by the
researcher through treatment or intervention to observe its effect on the dependent
variable. The process by which researchers purposefully change, alter, or influence the
independent variables (IVs), which are also called treatment variables or factors,
b. Randomization: Randomization in an experiment refers to a random assignment of
participants to the treatment in an experiment. It means that every subject has an equal
chance of being assigned to the experimental or control group. It is used in true
experimental research designs to minimize the threat of internal validity of the study
and to eliminate the effect of extraneous variables on dependent variables.
c. Control: It is another essential element of a true experimental design. It refers to the
use of a control group and controlling the effects of extraneous variables on the
dependent variable in which the researcher is interested. The Control groups are
essential to experimental design, When, researchers are interested in the impact of a
new treatment.
The control group could be of the following three types:
• Negative control: In this type of control group, the subject receives neither a
placebo nor any other type of treatment or intervention.
• Clear control: The subjects in this type of control group receive a placebo.
• Positive control: The subjects in the control group receive other treatment or
experimental intervention.
2. Observational Research Design:
It is also known as epidemiological or noninterventional or nonexperimental
research design. It is one of the broad categories of research designs in which the
researcher observes the phenomena as they occur naturally and no external
variables are introduced. It is a research design in which neither the variables are
5. 5
ASSIGNMENT
deliberately manipulated nor the setting is controlled. The observational design is
subdivided into descriptive, including cross-sectional, case report or case series,
and correlational, and analytic which includes cross-section, case-control, and
cohort studies.
I. Descriptive Research Design: The purpose of descriptive studies is to observe,
describe and document aspects of a situation as it naturally occurs, and sometimes to
serve as a starting point for hypothesis generation or theory development.
II. Cross-sectional: In a cross-sectional study, the investigator measures the outcome and
the exposures in the study participants at the same time.
III. Case Report: A case report is a detailed report of the symptoms, signs, diagnosis
treatment, and follow-up of an individual patient.
IV. Case Series: A group or series of case reports involving patients who were given
similar treatment.
V. Correlational: A correlational research design investigates relationships between
variables without the researcher controlling or manipulating any of them.
VI. Analytical Research: It is a specific type of research that involves critical thinking
skills and, the evaluation of facts and information relative to the research being
conducted.
VII. Case-control: In a case-control study, participants are selected for the study based on
their outcome status. Thus, some participants have the outcome of interest (referred to
as cases), whereas others do not have the outcome of interest (referred to as controls).
The investigator then assesses the exposure in both these groups.
VIII. Cohort Study: is a type of nonexperimental or observational study design. In a cohort
study, the participants do not have the outcome of interest to begin with. They are
selected based on the exposure status of the individual. They are then followed over
time to evaluate for the occurrence of the outcome of interest.
3. Diagnostic Research Design: This research design seeks to identify the underlying cause
of a certain condition or phenomenon. It is used to evaluate the frequency with which
something occurs and its interaction with other element.
4. Exploratory Research Design: It is a methodology approach that investigates research
questions that have not previously been studied in depth.
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ASSIGNMENT
SAMPLING
Introduction: A part of the population is known as sample. Sampling is a process of selecting
representative units from an entire population of a study. The target population is the total group
of individuals from which the sample might be drawn. Sampling helps in time and cost saving.
Purpose of sampling:
Economical: With the help of sampling, the researcher can save lots of time, money and resources
to study a phenomenon. Therefore, sampling provides an economical option for the researcher to
generate empirical evidences.
Improve quality of data: It is proven fact that when a person handles less amount of work or less
number of people, it is easier to ensure the quality of the outcome.
Quick study result: Studying an entire population itself will take a lot of time, and generating
research results of a large mas swill be almost impossible as most research studies have time limits.
But with a sample, it is possible to generate study results fast, which is one of the important
objectives of every researcher.
Advantage of sampling
➢ Limit the number of units for study. (Unit– the object whose characteristics are studied)
➢ It makes study feasible in respect of budget, time and logistics.
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ASSIGNMENT
Characteristics of a good sample
➢ Representativeness: A representative sample is that whose key characteristics are closely
related to those of the population. Representativeness of a sample makes it possible to generalize
the findings for the population. A sample must be representative of the population.
➢ Accuracy: an accurate sample is one which exactly represents the population.
➢ Precision: Precision is measured by standard error. The sample should be free from simple
random sampling errors or sampling bias.
➢ Size: a good sample must be adequate in size in order to be reliable.
Types of sampling: There are two generic types
A) Random or probability sampling
B) Non-Random or Non-probability sampling
A) Random or probability sampling: It is based on theory of probability. It provides a known
non-zero chance of selection for each population element. In this every subject in a population has
equal chance to be selected as a study sample. In probability sampling techniques, the chances of
systemic bias are relatively less because subjects are randomly selected. There are four methods
of random sampling.
1. Simple random sampling
2. Systematic random sampling
3. Stratified random sampling
4. Cluster sampling
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ASSIGNMENT
1.Simple random sampling: This sampling technique gives each element an equal and
independent chance of being selected.
➢ Drawing sample numbers by using (a) lottery method, (b)a tables of random numbers or (c) by
using computer.
➢ This type of sampling is suited for a small homogeneous population.
➢ This is one of the easiest methods.
2. Systematic random sampling: In this sampling, elements are selected from the population at
a uniform interval that is measured in time, order, or space. It is simpler than random sampling.
3.Stratified random sampling: In this method we divide the population into relatively
homogeneous groups, called strata. Then we use one of the two approaches- Either we select at
random from each stratum a specified number of elements corresponding to the proportion of that
stratum in the population as a whole or we draw an equal number of elements from each stratum
and give weight to the results according to the stratum’s proportion of total population. Hence there
are two method of sampling – 1. Equal allocation and 2. Proportional allocation
4.Cluster sampling: In this method we divide the population into the group or clusters, and then
select a random sample of these clusters. We assume that these individual clusters are
representative of the population as a whole. A well-designed cluster sampling procedure can
produce a more precise sample at considerably less cost than that of simple random sampling.
➢ Needs of randomization: The process of assigning the study subjects randomly to either the
treatment or control group is called randomization.
• It is essential to control various known or even unknown biases at the beginning of the
trial and during the course of trial. It is very helpful in achieving this objective.
• Randomization always remove the bias influencing the result.
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ASSIGNMENT
• Randomization allows for valid statistical interpretation of raw data.
• It eliminates selection bias.
• It avoids systemic difference between groups.
• It produces comparable group.
B) Non-Random or Non probability sampling: It is not based on the theory of probability. This
sampling does not provide a chance of selection to each population element. This method of
sampling is simple, convenience and low cost.it may be classified into –
1. Convenience or accidental sampling: It means selecting sample units in a just “hit and miss”
fashion. It the cheapest, simplest and not require any statistical expertise. But this is highly biased
because of researcher’s subjectivity.
2. Purposive or judgmental sampling: This method means deliberate selection of sample units
that conform to some predetermined criteria. It may not be true representative of their parent
population.
3. Quota sampling: This is a form of convenient sampling involving selection of quota groups of
accessible sampling units by traits such as sex, age, social class. Etc.
4. Snow-ball sampling: This is a method of building up a list or a sample of a special population
by using an initial set of its members as informants.it is useful for smaller population for which no
frame is readily available.