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Excimer Laser for Hyperopia: Wider Limits Dan Z Reinstein MD MA(Cantab) FRCSC FRCOphth  1,2,3,4  ’  ’
Financial Disclosure ,[object Object],[object Object],[object Object]
Outcome
MEL80 High Hyperopia Outcomes ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
MEL80 High Hyperopia: Monocular Efficacy
UCVA measurement
MEL80 High Hyperopia: Accuracy Within  ±0.50 D 65% Within  ±1.00 D 93%
MEL80 High Hyperopia: Accuracy
MEL80 High Hyperopia: Safety – BSCVA
Retinal Image magnification in hyperopia Decreased retinal image size will result in a decrease in BSCVA  Refraction Vertex distance Change in retinal image size Ratio retinal image size glasses/Rx surgery Theoretical VA after corneal Rx surgery  +4.00 D 12 mm -4.8% 0.95 20/21 +4.00 D 16 mm -6.4% 0.94 20/21 +7.00 D 12 mm -8.4% 0.92 20/22 +7.00 D 16 mm -11.2% 0.89 20/23
MEL80 High Hyperopia: Contrast Sensitivity * * * * * Statistically significant (p<0.05)
Stability ,[object Object],[object Object],[object Object],[object Object],Change in mean keratometry Change in refraction ,[object Object],[object Object]
History of Hyperopic LASIK
Hyperopic Ablation Profiles ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Hyperopic Ablation Profiles  (cont) ,[object Object],[object Object],[object Object],[object Object],[object Object]
1 st  Generation Hyperopic Profile – 1997 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
1 st  Generation Hyperopic Profile – 1997 ,[object Object],[object Object],[object Object],[object Object],[object Object]
Early Hyperopic Treatment – 1999
[object Object],[object Object],1st Generation Hyperopic Profile – 1997
2 nd  Generation Hyperopic Profile - 2007 ,[object Object],[object Object],[object Object],Artemis Epithelium Orbscan Topography 5-mm
MEL80 Topography Guided Retreatment ,[object Object],[object Object],Artemis Epithelium Pre Post Change 7-mm
Improvements in technique of hyperopic LASIK
Ablation Profile Design Improvements ,[object Object],[object Object],[object Object],VISX S2 5.5mm VISX S2 5.5mm B&L 217c 6mm
3 rd  Generation Ablation Profile Design ,[object Object],[object Object],[object Object],[object Object],[object Object],Pre Post Change MEL80 +5.50 ablation
Epithelial Changes in Newer Ablation Profiles ,[object Object],[object Object],[object Object],[object Object],Artemis Epithelium
Awareness of “Apical Syndrome” ,[object Object],[object Object],[object Object],[object Object]
Epithelial Thinning in Hyperopic Ablation   (Reinstein et al. unpublished data) ,[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],Epithelial Thinning in Hyperopic Ablation  (Reinstein et al. unpublished data)
Apical Syndrome ,[object Object],[object Object],[object Object]
Apical Syndrome:  Treated by Trans-Epi PTK ,[object Object],AGTEPTK Simulation Pre 3 mo 6 wks 1 day Epithelium & Scar Depth
Techniques: Two-stage treatment ,[object Object],[object Object],[object Object],[object Object],Measurement of thinnest epithelium Calculation of treatable remaining hyperopia based on vertex epithelial thickness
Centration on the Corneal Vertex (approximates the visual axis)
Centration of Hyperopic Correction ,[object Object],Phoroptor Lens No Angle Kappa Large Angle Kappa Phoroptor Lens
Centration of Hyperopic Correction ,[object Object],Centre on the visual axis Centre on the pupil Ablation Ablation
Flap Centration ,[object Object],Orbscan Eye Image Hansatome Flap Hansatome Ring/Flap OD OS
Centration of Ablation ,[object Object],Orbscan Eye Image MEL80 Eye Tracker Images rotated 180   as taken from surgeon’s microscope view
Centration of Hyperopic Ablation ,[object Object],[object Object],[object Object]
Wavefront correction for Hyperopia? ,[object Object],[object Object],Pupil centre   (  )  and the  visual axis (  )  ARE NOT coincident: 85% of hyperopes have a positive angle kappa Patients with large kappa will have large coma (relative to pupil centre=OSA) HOWEVER they do not have symptoms of coma ! Wavefront guided treatment would move the corneal vertex to a new position by flattening the “so-called” coma (relative to pupil centre) – this would certainly induce  symptoms  of coma!
Example: Hyperopic Postop - OD Patient’s subjective symptoms OD Wavefront (Pupil   Centre ) Visual Symptoms do NOT match PSF by wavefront ( pupil centre)
Example: Hyperopic Postop - OD Patient’s subjective symptoms OD Wavefront (Corneal  Vertex) Visual Symptoms DO match PSF by wavefront ( corneal vertex)
Summary
Pearls for High Hyperopic LASIK ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
LASIK or IOLs? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Excimer Laser for Hyperopia: What Are Age and Degree Limits? Dan Z Reinstein MD MA(Cantab) FRCSC FRCOphth  1,2,3,4  ’  ’ Thank You
Why is corneal treatment best? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Outcomes: Efficacy  ,[object Object],[object Object],[object Object],[object Object],[object Object],Efficacy: UCVA  Rx treated ≥  20/20 ≥  20/40 Artisan IOL FDA study [1] +4.00 to +12.00D 21.4% 85.5% Artisan phakic IOL [2] +2.75 to +9.25 D 67%  ≥ 20/25 89% Staar ICL [3] +4.00 to +11.00D 8% 63% PRL  (Carl Zeiss Meditec)  [4] +4.00 to +6.00D 12.5% 100% RLE & multifocal IOL [5] +1.75 to +6.00D 31% 100% LASIK – MEL80 +4.00 to +7.00 D 71% 100%
Outcomes: Accuracy Phakic IOLs ,[object Object],[object Object],[object Object],[object Object],Accuracy within Rx treated ± 0.50D ± 1.00 D Artisan IOL FDA study [1] +4.00 to +12.00D 65.5% 98.2% Artisan phakic IOL [2] +2.75 to +9.25 D 50% 78% Artisan phakic IOL [3] +3.00 to +11.00D NA 81.8% Posterior chamber phakic IOL [4] +4.00 to +11.00D 58% 79% LASIK – MEL80 +4.00 to +7.00 D 65% 93%
Outcomes: Accuracy RLE (PCIOLs) ,[object Object],[object Object],[object Object],Accuracy within Rx treated ± 0.50D ± 1.00 D RLE & multifocal IOL [5] +1.75 to +6.00D 88% 100% RLE Staar/Rayner IOL [6] +4.75 to +13.00 D 70% 90% Acrysoft RLE [2] +2.75 to +7.50 D 55% 91% LASIK – MEL80 +4.00 to +7.00 D 65% 93%
Outcomes: Contrast Sensitivity – Intraocular Tx Below normal contrast sensitivity for both ReSTOR lens types
Safety: loss of lines ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Lose 2 lines Lose 1 line PRL Medennium [1] 0 31.25 Staar or Rayner  CLE [2] 0 10 Array CLE [3] 0 12 Artisan [4] 0 0 Acrysof CLE [4] 0 0 PRL [5] 4 NA Artisan [6] 0.1 38.4 MEL80 LASIK 0 23
Catastrophic complications
Catastrophic complications ,[object Object],[object Object],[object Object],[object Object]
Catastrophic complications ,[object Object],[object Object],[object Object],1. Lundstrom M. Endophthalmitis after cataract surgery: a nationwide prospective study evaluating incidence in relation to incision type and location. Ophthalmology. 2007; 114: 870-886.
Catastrophic complications ,[object Object],[object Object],[object Object],1. Ray S, D’Amico DJ. Pseudophakic cystoid macular edema. Semin Ophthalmol. 2002;17:167-180. 2. Powe NR, Schein OD, Gieser SC, et al. Synthesis of the literature on visual acuity and complications following cataract extraction with intraocular lens implantation. Arch Ophthalmol. 1994;112:239-252.
Catastrophic complications ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],2, Guell et al – Five-year follow-up of 399 phakic Artisan-Verisyse implantation for myopia, hyperopia, and/or astigmatism. Ophthalmology 2007;31 3. Ruiz-Moreno et al. Retinal detachment in myopic eyes after phakic intraocular lens implantation. J Refract Surg 2006;22(3): 247-52.
Catastrophic complication: Ectasia Reported Rate In Context ,[object Object],Report No. of Ectasia/ No. Procedures Percentage Pallikaris JCRS 2001 19/2,873 0.66% Lyle JCRS 2001 1/332 0.30% Rad JRS 2004 14/6,941 0.20% Reinstein JRS 2006 6/5,212 0.12%
Why is corneal treatment best? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Other Complications
Corneal refractive surgery
Complication Rate –  Reinstein personal series FLAP COMPLICATIONS Eyes out of 11,600 % Lose 2 Lines Free Cap 1 (0.01%) 0.0000000% Thin Flap 2 (0.02%) 0.0000000% Incomplete Flap (no ablation) 6 (0.05%) 0.0000000% Corneal Perforation 0 (0.00%) 0.0000000% Blindness (total loss of vision) 0 (0.00%) 0.0000000% Corneal scarring reducing vision 0 (0.00%) 0.0000000% Inflammation with decrease of vision 1 (0.01%) 0.0000000% Infection 0 (0.00%) 0.0000000% Epithelial Ingrowth (requiring further surgery) 21 (0.19%) 0.0000000% Need for corneal transplantation 0 (0.00%) 0.0000000% Keratectasia 0 (0.00%) 0.0000000% LASER COMPLICATIONS Eyes out of 11,600 % Lose 2 Lines Visually sig. decentrations 0 (0.00%) 0.0000000% Laser parameter data entry error 3 (0.03%) 0.0000000%
Lens refractive surgery
Challenge: SIZING of Phakic IOL ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Anterior Segment Correlation Publications ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Correlations Between Anterior Segment Diameters Angle Diameter Sulcus Diameter White-to-White Angle Diameter Multivariate 6.4% 3.0% 38.0% 32.7% 26.7% Error >0.50 mm Error >0.50 mm Sig. Variables: Angle Diameter Anterior Chamber Depth Sig. Variables: White-to-white Corneal thickness Minimum keratometry Reinstein DZ, Archer TJ, Silverman RH, Rondeau MJ, Coleman DJ. Can Conventional Anterior Segment Measurements be used to Calculate Angle-to-Angle Diameter or Sulcus-to-Sulcus Diameter? J Refract Surg. [In Press].
Anterior Segment – IOL in Recessed Sulcus OD OS
Sizing Error: ICL WTW  OD = 11.5 OS = 11.5
Sizing Error: ICL WTW  OD = 12.0 OS = 12.0
Sizing Error: ICL WTW  OD = 11.5 OS = 12.0
Post-operative risks Lens Refractive Surgery Posterior Capsular Opacification Endothelial cell loss Uveitis Cataract formation Pigment Dispersion Retinal Detachment Posterior dislocation Pupillary Block Pupil ovalisation Hypertension - Glaucoma Lens rotation Glare and Halos
Complications: Poor Centration  Alio et al – The Kelman duet phakic intraocular lens: 1-year results – J Refract Surg. 2007;23(9):868-79
Artisan  Phakic IOL Digital image preop  Slide Courtesy B Dick MD Digital image postop
Artisan  Phakic IOL Wavefront OPD overall (top) and higher orders only (bottom), 6th order Digital image preop  Slide Courtesy B Dick MD
Artisan  Phakic IOL Wavefront OPD overall (top) and higher orders only (bottom), 6th order Digital image postop  Slide Courtesy B Dick MD
Complications: Dislocation ,[object Object],[object Object],[object Object]
Complications: PCO ,[object Object],[object Object],[object Object],[object Object]
Case Example: Post RLE ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Case Example: Post RLE ,[object Object],[object Object],[object Object]
Case Example: Post CLE ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Case Example: Post CLE
Case Example: Post CLE OD OS
Case Example: Post CLE ,[object Object],[object Object],[object Object],[object Object],[object Object]
Case Example: Post CLE ,[object Object],[object Object]
Case Example: Post RLE – OD ,[object Object],[object Object]
Case Example: Post RLE – OS ,[object Object],[object Object]
Endothelial cell count ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Endothelial cell loss ,[object Object],[object Object],Before After phakic IOL  Kim et al – Corneal endothelial decompensation after iris-claw phakic intraocular lens implantation – J Cataract Refract Surg. 2008; 34(3):517-9. Alio et al – The Kelman duet phakic intraocular lens: 1-year results – J Refract Surg. 2007;23(9):868-79 Stulting et al – Three-year results of Artisan/Verisyse phakic intraocular lens implantation. Results of the United States FDA clinical trial. Ophthalmology. 2008; 115(3): 464-472 Guell et al – Five-year follow-up of 399 phakic Artisan-Verisyse implantation for myopia, hyperopia, and/or astigmatism. Ophthalmology 2007;31 Gierek-Ciaciura et al. Correction of high myopia with different phakic anterior chamber intraocular lenses: ICARE angle-supported lens and Verisyse iris-claw lens. Graefes Arch Clin Exp Ophthalmol. 2007;245(1): 1-7.
Complications: Pupil ovalisation  Alio et al – The Kelman duet phakic intraocular lens: 1-year results – J Refract Surg. 2007;23(9):868-79
Complications: Cataract Formation Garcia-Feijoo et al – JCRS – 2003;29:1932-39 Brandt JD et al – Am J Ophthalmology 2001;131:260-263 Alio et al – Angle-supported anterior chamber phakic intraocular lens explantation causes and outcome. Ophthalmology 2006;113(12): 2213-20
Uveitis/Iridocyclitis ,[object Object],[object Object],[object Object],[object Object]
Complications: Synechiae Artisan +6.00
Complications: Synechiae
Complications: Pigment Dispersion  ,[object Object],[object Object]
Complications: Ocular Hypertension ,[object Object],[object Object]
Other Complications ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Why is corneal treatment best? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Ease of attaining exact target refraction (enhancement)
Advantages of corneal treatment ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Easier to perform two treatments on the cornea
Why is corneal treatment best? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Patient Preference ,[object Object],[object Object],[object Object],[object Object]
Why is corneal treatment best? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Simultaneously provides good visual function at distance and near
[object Object],[object Object],[object Object],Laser Blended Vision:  Increased Depth of Field OD Manifest BSCVA UCVA Near Pre Op +3.00 -0.75 x 115 20/20 20/63 N24 1 Year +0.25 -0.75 x 152 20/12.5 20/20 N6 OS Manifest BSCVA UCVA Near Pre Op +3.25 -0.75 x 90 20/20 20/80 N18 1 Year -0.25 -0.50 x 5 20/20 20/25 N6
Laser BV  High Hyperopic  LASIK +7.00 57 y.o. OD OS Binocular Pre Manifest +6.75 -0.75 x 43 +7.00 -0.50 x 120 BSCVA 20/25 20/20 6 Mo Post Enh UCVA 20/32 20/20 20/20 & N5 Manifest -1.25 sph +0.25 sph BSCVA 20/20 20/20
Laser BV  High Hyperopic  LASIK +7.00 ,[object Object],[object Object],[object Object],[object Object],[object Object],-1.25 “nominal rx” -0.50 “distance” -2.00 “near”
Presbyopic Correction: Intra-Ocular
Limitations of intraocular Tx - young population ,[object Object],[object Object],[object Object],[object Object],Limited use in the young population ,[object Object],[object Object],[object Object]
Limitations in the presbyopic population ,[object Object],[object Object],[object Object],[object Object],[object Object]
Multifocal IOLs ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Multifocal IOLs Binocular UCVA 4 to 8% experience severe night vision disturbances [2,3] ,[object Object],[object Object],[object Object],Near Intermediate Distance ReSTOR [1] 88%  ≥ 20/32 24%  ≥ 20/32 46%  ≥ 20/20 ReZoom [1] 44%  ≥ 20/32 50%  ≥ 20/32 60%  ≥ 20/20 Moderate Glare Moderate Halos ReSTOR [1] 20% 14% ReZoom [1] 30% 28%
Accommodative IOLs Binocular UCVA ,[object Object],[object Object],Accommodative IOLs provide limited accommodative ability: Objective measurements unable to demonstrate any significant forward movement of the IOL [2] Near Distance Tetraflex [1] 48.1%  ≥ 20/40 50.6%  ≥ 20/20
Presbyopic Advantages of Corneal Treatment ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
MEL80 Micro-Monovision Outcomes ,[object Object]
Conclusion
Why is corneal treatment best? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Excimer Laser for Hyperopia: Wider Limits Dan Z Reinstein MD MA(Cantab) FRCSC FRCOphth  1,2,3,4 1. London Vision Clinic, London, UK 2. St. Thomas’ Hospital - Kings College, London, UK 3. Weill Medical College of Cornell University, New York, USA 4. Centre Hospitalier National d’Ophtalmologie, (Pr. Laroche), Paris, France
[object Object],[object Object],Contrast Sensitivity: Stratified by Age * * * * * * * * * Analysed as change in patches e.g. loss 2 patches (-2)
Alternative: Multi-focal IOL Below normal contrast sensitivity for both ReSTOR lens types

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Excimer Laser for Hyperopia: Wider Limits

  • 1. Excimer Laser for Hyperopia: Wider Limits Dan Z Reinstein MD MA(Cantab) FRCSC FRCOphth 1,2,3,4  ’  ’
  • 2.
  • 4.
  • 5. MEL80 High Hyperopia: Monocular Efficacy
  • 7. MEL80 High Hyperopia: Accuracy Within ±0.50 D 65% Within ±1.00 D 93%
  • 9. MEL80 High Hyperopia: Safety – BSCVA
  • 10. Retinal Image magnification in hyperopia Decreased retinal image size will result in a decrease in BSCVA Refraction Vertex distance Change in retinal image size Ratio retinal image size glasses/Rx surgery Theoretical VA after corneal Rx surgery +4.00 D 12 mm -4.8% 0.95 20/21 +4.00 D 16 mm -6.4% 0.94 20/21 +7.00 D 12 mm -8.4% 0.92 20/22 +7.00 D 16 mm -11.2% 0.89 20/23
  • 11. MEL80 High Hyperopia: Contrast Sensitivity * * * * * Statistically significant (p<0.05)
  • 12.
  • 14.
  • 15.
  • 16.
  • 17.
  • 19.
  • 20.
  • 21.
  • 22. Improvements in technique of hyperopic LASIK
  • 23.
  • 24.
  • 25.
  • 26.
  • 27.
  • 28.
  • 29.
  • 30.
  • 31.
  • 32. Centration on the Corneal Vertex (approximates the visual axis)
  • 33.
  • 34.
  • 35.
  • 36.
  • 37.
  • 38.
  • 39. Example: Hyperopic Postop - OD Patient’s subjective symptoms OD Wavefront (Pupil Centre ) Visual Symptoms do NOT match PSF by wavefront ( pupil centre)
  • 40. Example: Hyperopic Postop - OD Patient’s subjective symptoms OD Wavefront (Corneal Vertex) Visual Symptoms DO match PSF by wavefront ( corneal vertex)
  • 42.
  • 43.
  • 44. Excimer Laser for Hyperopia: What Are Age and Degree Limits? Dan Z Reinstein MD MA(Cantab) FRCSC FRCOphth 1,2,3,4  ’  ’ Thank You
  • 45.
  • 46.
  • 47.
  • 48.
  • 49. Outcomes: Contrast Sensitivity – Intraocular Tx Below normal contrast sensitivity for both ReSTOR lens types
  • 50.
  • 52.
  • 53.
  • 54.
  • 55.
  • 56.
  • 57.
  • 60. Complication Rate – Reinstein personal series FLAP COMPLICATIONS Eyes out of 11,600 % Lose 2 Lines Free Cap 1 (0.01%) 0.0000000% Thin Flap 2 (0.02%) 0.0000000% Incomplete Flap (no ablation) 6 (0.05%) 0.0000000% Corneal Perforation 0 (0.00%) 0.0000000% Blindness (total loss of vision) 0 (0.00%) 0.0000000% Corneal scarring reducing vision 0 (0.00%) 0.0000000% Inflammation with decrease of vision 1 (0.01%) 0.0000000% Infection 0 (0.00%) 0.0000000% Epithelial Ingrowth (requiring further surgery) 21 (0.19%) 0.0000000% Need for corneal transplantation 0 (0.00%) 0.0000000% Keratectasia 0 (0.00%) 0.0000000% LASER COMPLICATIONS Eyes out of 11,600 % Lose 2 Lines Visually sig. decentrations 0 (0.00%) 0.0000000% Laser parameter data entry error 3 (0.03%) 0.0000000%
  • 62.
  • 63.
  • 64. Correlations Between Anterior Segment Diameters Angle Diameter Sulcus Diameter White-to-White Angle Diameter Multivariate 6.4% 3.0% 38.0% 32.7% 26.7% Error >0.50 mm Error >0.50 mm Sig. Variables: Angle Diameter Anterior Chamber Depth Sig. Variables: White-to-white Corneal thickness Minimum keratometry Reinstein DZ, Archer TJ, Silverman RH, Rondeau MJ, Coleman DJ. Can Conventional Anterior Segment Measurements be used to Calculate Angle-to-Angle Diameter or Sulcus-to-Sulcus Diameter? J Refract Surg. [In Press].
  • 65. Anterior Segment – IOL in Recessed Sulcus OD OS
  • 66. Sizing Error: ICL WTW OD = 11.5 OS = 11.5
  • 67. Sizing Error: ICL WTW OD = 12.0 OS = 12.0
  • 68. Sizing Error: ICL WTW OD = 11.5 OS = 12.0
  • 69. Post-operative risks Lens Refractive Surgery Posterior Capsular Opacification Endothelial cell loss Uveitis Cataract formation Pigment Dispersion Retinal Detachment Posterior dislocation Pupillary Block Pupil ovalisation Hypertension - Glaucoma Lens rotation Glare and Halos
  • 70. Complications: Poor Centration Alio et al – The Kelman duet phakic intraocular lens: 1-year results – J Refract Surg. 2007;23(9):868-79
  • 71. Artisan Phakic IOL Digital image preop Slide Courtesy B Dick MD Digital image postop
  • 72. Artisan Phakic IOL Wavefront OPD overall (top) and higher orders only (bottom), 6th order Digital image preop Slide Courtesy B Dick MD
  • 73. Artisan Phakic IOL Wavefront OPD overall (top) and higher orders only (bottom), 6th order Digital image postop Slide Courtesy B Dick MD
  • 74.
  • 75.
  • 76.
  • 77.
  • 78.
  • 80. Case Example: Post CLE OD OS
  • 81.
  • 82.
  • 83.
  • 84.
  • 85.
  • 86.
  • 87. Complications: Pupil ovalisation Alio et al – The Kelman duet phakic intraocular lens: 1-year results – J Refract Surg. 2007;23(9):868-79
  • 88. Complications: Cataract Formation Garcia-Feijoo et al – JCRS – 2003;29:1932-39 Brandt JD et al – Am J Ophthalmology 2001;131:260-263 Alio et al – Angle-supported anterior chamber phakic intraocular lens explantation causes and outcome. Ophthalmology 2006;113(12): 2213-20
  • 89.
  • 92.
  • 93.
  • 94.
  • 95.
  • 96. Ease of attaining exact target refraction (enhancement)
  • 97.
  • 98.
  • 99.
  • 100.
  • 101. Simultaneously provides good visual function at distance and near
  • 102.
  • 103. Laser BV High Hyperopic LASIK +7.00 57 y.o. OD OS Binocular Pre Manifest +6.75 -0.75 x 43 +7.00 -0.50 x 120 BSCVA 20/25 20/20 6 Mo Post Enh UCVA 20/32 20/20 20/20 & N5 Manifest -1.25 sph +0.25 sph BSCVA 20/20 20/20
  • 104.
  • 106.
  • 107.
  • 108.
  • 109.
  • 110.
  • 111.
  • 112.
  • 114.
  • 115. Excimer Laser for Hyperopia: Wider Limits Dan Z Reinstein MD MA(Cantab) FRCSC FRCOphth 1,2,3,4 1. London Vision Clinic, London, UK 2. St. Thomas’ Hospital - Kings College, London, UK 3. Weill Medical College of Cornell University, New York, USA 4. Centre Hospitalier National d’Ophtalmologie, (Pr. Laroche), Paris, France
  • 116.
  • 117. Alternative: Multi-focal IOL Below normal contrast sensitivity for both ReSTOR lens types

Editor's Notes

  1. First, I’m going to quickly outline the outcomes of the cross linking treatments done at the London Vision Clinic
  2. First, I’m going to quickly outline the outcomes of the cross linking treatments done at the London Vision Clinic
  3. First, I’m going to quickly outline the outcomes of the cross linking treatments done at the London Vision Clinic
  4. First, I’m going to quickly outline the outcomes of the cross linking treatments done at the London Vision Clinic
  5. Update numbers
  6. First, I’m going to quickly outline the outcomes of the cross linking treatments done at the London Vision Clinic
  7. Here are some examples of right and left pairs of ICL implanted into patients, based on the traditional white-to-white prediction algorithms. In this image we see two perfectly vaulted lenses, left and right, in an eye with WTW of 11.5 on both sides.
  8. This case, shows that despite the same WTW on both sides, the vault was excessive on the right, but non-existent on the left.
  9. In this eye, the WTW was different on both sides, but the lenses were oversized on both sides by about the same amount.
  10. This case shows a patient after implantation of an Artisan phakic IOL. On the left you see a digital image of the implanted lens. The red circle marks the pupil center and the grey circle marks the lens optic. Shown on the right is the wavefront measurement with the WASCA Analyzer. Especially after refractive procedures which didn‘t modify corneal curvature, i.e. phakic IOLs etc.., wavefront analysis is an indispensable diagnostic instrument. The spherical surfaces of the Artisan IOL cause a small amount of spherical aberration Z(4,0) of –0,5µm. This is a result of the spherical lens surfaces and can be also found in standard IOL. Although the lens seems to be well centered, the coma of -1,38µm must be the result of the lens centration. In this case the WASCA result clearly confirmed the poor vision of the patient. Because of the corresponding subjective and objective findings the lens has been repositioned to improve the visual outcome.
  11. Here you see the situation after repositioning of the lens. On the left you see again the digital image of the implanted lens. The circles show that the center of the lens is not pupil centered anymore. Shown on the right is the wavefront measurement with the WASCA Analyzer. The coma coefficient has been decreased to -0,59µm due to the repositioning. The patients visual perfromance improved dramatically. This encourages us to perform wavefront measurement on all problem patients.
  12. First, I’m going to quickly outline the outcomes of the cross linking treatments done at the London Vision Clinic
  13. First, I’m going to quickly outline the outcomes of the cross linking treatments done at the London Vision Clinic
  14. This example shows a hyperopic patient where the post op result was close to plano, however, both eyes could see N6 at near A 59 year old patient would only be expected to see N6 at near with an add of around -1.50 to -2.00 D
  15. Successful high plus treatment
  16. Getting N6 from just -0.75 cyl in a 60 year old patient
  17. First, I’m going to quickly outline the outcomes of the cross linking treatments done at the London Vision Clinic