Radiotherapy is used in the management of oral cancer for curative and palliative purposes. It can be delivered as primary treatment combined with chemotherapy for organ preservation or after surgery as adjuvant treatment. Newer radiotherapy techniques like IMRT allow higher doses to be delivered to tumors while reducing damage to nearby organs. Side effects depend on treatment dose and area irradiated, and may include mucositis, xerostomia, skin changes, osteoradionecrosis and rare complications like carotid rupture. Ongoing research aims to reduce toxicity through altered fractionation schedules and novel delivery methods.