This document discusses how radiographs can aid in the diagnosis of periodontal disease. Radiographs reveal changes to calcified tissues but not current cellular activity. Normal interdental septa appear as thin radiopaque lines along the alveolar crest. Early periodontal disease leads to disruption of the lamina dura and crestal cortication. As the disease progresses, bone loss appears as wedge-shaped radiolucencies and reduced height of the interdental bone. Furcation involvement and periodontal abscesses can also be detected radiographically, though clinical examination is still needed.
This presentation describes the gingival recession, its classifications and theories of pathogenesis and different etiological factors in its progression.
The future of dentistry and periodontics lies in regeneration. The goals of periodontal therapy lies in not only the arrest of periodontal disease progression but also regeneration of the lost periodontal structures. This presentation provides a review of the current understanding of the regeneration of the periodontium and the procedures involved to restore the periodontal tissues around the teeth.
In periodontology, classifications are widely used to categorize defects due to periodontitis according to their etiology, diagnosis, treatment and prognosis.
Several classifications have been proposed in the literature in order to facilitate the diagnosis of gingival recessions.
Furcation involvement is a common sequela of severe chronic periodontal disease. Its effective management has a profound influence on the outcome of periodontal therapy.
This presentation describes the gingival recession, its classifications and theories of pathogenesis and different etiological factors in its progression.
The future of dentistry and periodontics lies in regeneration. The goals of periodontal therapy lies in not only the arrest of periodontal disease progression but also regeneration of the lost periodontal structures. This presentation provides a review of the current understanding of the regeneration of the periodontium and the procedures involved to restore the periodontal tissues around the teeth.
In periodontology, classifications are widely used to categorize defects due to periodontitis according to their etiology, diagnosis, treatment and prognosis.
Several classifications have been proposed in the literature in order to facilitate the diagnosis of gingival recessions.
Furcation involvement is a common sequela of severe chronic periodontal disease. Its effective management has a profound influence on the outcome of periodontal therapy.
Coronal advanced flap in combination with a connective tissue graft. Is the t...MD Abdul Haleem
Coronal advanced flap in combination with a connective tissue graft. Is the thickness of the flap a predictor for root coverage? - A prospective clinical study.
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this ppt depicts pattern of bone destruction. its a very good slide show showing the process of bone formation, bone destruction and their patterns in periodontal diseases.
Coronal advanced flap in combination with a connective tissue graft. Is the t...MD Abdul Haleem
Coronal advanced flap in combination with a connective tissue graft. Is the thickness of the flap a predictor for root coverage? - A prospective clinical study.
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"A Journal Club Presentation"
this ppt depicts pattern of bone destruction. its a very good slide show showing the process of bone formation, bone destruction and their patterns in periodontal diseases.
Radiographs play an important role in the diagnosis and treatment of periodontal diseases. They provide important information regarding the anatomical structures and periodontal bone loss.
This report, prepared by the student at the College of Dentistry, Hassan Atheed , in the third phase discusses scientific topics, but it maybe did not be 100% complete.
A radiograph is only one part of the diagnostic process. Usually one does NOT make a diagnosis solely from a radiograph. A diagnosis is made by the clinician once all the diagnostic information has been collected and analyzed collectively. An interpretation or a differential diagnosis is made from the radiograph.
One examines a radiograph and NOT an X-ray. Bear in mind that an X-ray cannot be seen. X-ray is a photon / beam of energy.
حسن عضيد
RADIOGRAPHIC EXAMINATIONS OF BONE LOSS AND PATTERN OF BONE LOSSMuhammadWasilKhan1
Radiographic examinations play a crucial role in the diagnosis and assessment of bone health and conditions related to bone loss. Bone loss is a common medical concern that can be caused by various factors, including aging, hormonal changes, metabolic disorders, and chronic diseases. Radiographic imaging techniques provide valuable insights into the extent and patterns of bone loss, helping healthcare professionals make informed decisions about patient care and treatment.
Radiographic interpretation of periodontal diseases /prosthodontic coursesIndian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
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Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
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Powerpoint include informations about oral disease and how it represent on dental radiographic image, (caries - cysts - hypercementosis - ...etc)
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What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
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development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
2. INTRODUCTION
The radiograph is a valuable aid in the:
Diagnosis of periodontal disease
Determination of the prognosis, and
Evaluation of the outcome of treatment.
However radiograph is an adjunct to the clinical examination, not a substitute
for it.
The radiograph reveals alteration in calcified tissues
It does not reveals current cellular activity but shows effects of past cellular
experience on the bone & roots.
3. NORMAL INTERDENTAL SEPTA
Radiographic evaluation of bone changes in periodontal diseases is based
mainly on appearance of interdental septa , because the relatively dense root
structure obscures the facial and lingual bony plates.
The interdental septum normally presents a thin radiopaque border that is
adjacent to the PDL and at alveolar crest, termed as Lamina dura.
4. Lamina dura appears radiographically as a continuous white line, but in
reality it is perforated by Numerous small foramina, Traversed by blood
vessels, lymphatics & nerves, which pass between the PDL & bone.
Because the lamina dura represents the bone surface lining the tooth socket,
the shape and position of the root & changes in the angulation of the X-ray
beam produce considerable variations in its appearance.
5. The width and shape of the interdental bone and the angle of the crest
normally vary according to the convexity of the proximal tooth surfaces and
the level of the cementoenamel junction (CEJ) of the approximating teeth.
The angulation of crest of interdental septum is generally parallel to line
between the CEJs of approximating teeth. When there is a difference in the
level of the CEJs, the crest of the interdental bone appears angulated rather
than horizontal.
The facio-lingual diameter of the bone is related to the width of proximal
root surface.
6. Radiographic Techniques
In conventional radiographs, periapical and bite-wing projections offer the
most diagnostic information and are most commonly used in the evaluation of
periodontal disease.
Standardized, reproducible techniques are required to obtain reliable
radiographs for pretreatment and posttreatment comparisons.
7. Prichard established the following four criteria to determine adequate
angulation of periapical radiographs:
1. The radiograph should show the tips of molar cusps with little or none of the
occlusal surface showing.
2. Enamel caps and pulp chambers should be distinct.
3. Interproximal spaces should be open.
4. Proximal contacts should not overlap unless teeth are out of line anatomically.
8. For periapical radiographs, the long-cone paralleling technique most
accurately projects the alveolar bone level.
The bisection-of-the-angle technique elongates the projected image, making
the bone margin appear closer to the crown; the level of the facial bone is
distorted more than that of the lingual.
9.
10. Inappropriate horizontal angulation results in tooth overlap, changes the
shape of the interdental bone image, alters the radiographic width of the PDL
space and the appearance of the lamina dura, and may distort the extent of
furcation involvement
11. Periapical radiographs frequently do not reveal the correct relationship between
the alveolar bone and the CEJ.
This is particularly in cases in which a shallow palate or floor of the mouth does
not allow ideal placement of the periapical film.
Bite-wing projections offer an alternative that better images periodontal bone
levels.
If the periodontal bone loss is severe and the bone level cannot be visualized on
regular bite-wing radiographs, films can be placed vertically to cover a larger area
of the jaws
12.
13. Bone Destruction in Periodontal
Disease
Early destructive changes of bone that do not remove sufficient mineralized
tissue cannot be captured on radiographs.
Therefore slight radiographic changes of the periodontal tissues suggest that
the disease has progressed beyond its earliest stages.
The earliest signs of periodontal disease must be detected clinically
14. Bone Loss
The radiographic image tends to underestimate the severity of bone loss.
The difference between the alveolar crest height and the radiographic
appearance ranges from 0 to 1.6 mm, mostly accounted for by x-ray
angulation.
15. Radiographs are an indirect method for determining the amount of bone loss
in periodontal disease;
they image the amount of remaining bone rather than the amount lost.
The amount of bone lost is estimated to be the difference between the
physiologic bone level and the height of the remaining bone.
A distance of 2 mm between CEJ and alveolar crest reflects normal
periodontium; this distance may be greater in older patients.
16. Pattern of Bone Destruction
In periodontal disease the interdental bone undergoes changes that affect the
lamina dura, crestal radiodensity, size and shape of the medullary spaces, and
height and contour of the bone.
Height of interdental bone may be reduced, with the crest perpendicular to
the long axis of the adjacent teeth (horizontal bone loss) or angular or
arcuate defects (angular, or vertical, bone loss) could form.
17.
18. Radiographs do not indicate the internal morphology or depth of craterlike
defects.
Also, radiographs do not reveal the extent of involvement on the facial and lingual
surfaces.
In most cases, it can be assumed that bone losses seen interdentally continue in
either the facial or the lingual aspect, creating a troughlike lesion.
A reduction of only 0.5 to 1.0 mm in the thickness of the cortical plate is sufficient
to permit radiographic visualization of the destruction of the inner cancellous
trabeculae. (importance: crater-like defects)
19.
20. Nutrient canals in the alveolar bone can
appear as linear and circular radiolucent
areas.
These canals can be seen more frequently
in the anterior mandible, although they
can be present throughout the alveolar
ridge
21. Differentiation between treated versus active periodontal disease can only be
achieved clinically.
Radiographically detectable changes in the normal cortical outline of the
interdental bone are corroborating evidence of destructive periodontal
disease
22. Radiographic Appearance of Periodontal
Disease
Fuzziness and disruption of lamina dura
Crestal cortication continuity is the earliest radiographic change in
periodontitis and results from bone resorption activated by extension of
gingival inflammation into the periodontal bone.
Depicting these early changes depends greatly on the radiographic technique,
as well as on anatomic variations (thickness and density of interdental bone,
position of adjoining teeth).
The presence of an intact crestal lamina dura may be an indicator of
periodontal health, whereas its absence lacks diagnostic relevance
23. Continued periodontal bone loss
and widening of the periodontal
space results in a wedge-shaped
radiolucency at the mesial or distal
aspect of the crest.
The apex of the area is pointed in
the direction of the root.
24. Subsequently, the destructive process extends across the alveolar crest, thus
reducing the height of the interdental bone.
The height of the interdental septum is progressively reduced by the
extension of inflammation and the resorption of bone
Frequently a radiopaque horizontal line can be observed across the roots of a
tooth. This opaque line demarcates the portion of the root where the labial or
lingual bony plate has been partially or completely destroyed from the
remaining bone-supported portion.
25.
26. Interdental craters are seen as irregular areas of reduced density on the
alveolar bone crests.
Craters are generally not sharply demarcated but gradually blend with the
rest of the bone.
Conventional radiographs do not accurately depict the morphology or depth of
interdental craters, which sometimes appear as vertical defects.
27. Definitive diagnosis of furcation involvement is made by clinical examination,
which includes careful probing with a specially designed probe (e.g., Nabers).
Radiographs are helpful, but root superimposition, caused by anatomic
variations and/or improper technique, can obscure radiographic
representation of furcation involvement.
28. To assist in the radiographic detection of furcation involvement, the following
diagnostic criteria are suggested:
1. The slightest radiographic change in the furcation area should be
investigated clinically, especially if there is bone loss on adjacent roots.
2. Diminished radiodensity in the furcation area in which outlines of bony
trabeculae are visible suggests furcation involvement.
3. Whenever there is marked bone loss in relation to a single molar root, it
may be assumed that the furcation is also involved.
29.
30. Periodontal Abscess
The typical radiographic appearance of the periodontal abscess is a discrete
area of radiolucency along the lateral aspect of the root. However, the
radiographic picture is often not characteristic. This can be due to the
following:
1. The stage of the lesion.
2. The extent of bone destruction and the morphologic changes of the bone.
3. The location of the abscess.
32. Localized aggressive periodontitis
Initially, bone loss in the maxillary and mandibular incisor and/or first molar
areas, usually bilaterally, resulting in vertical, arclike destructive patterns
As the disease progresses, loss of alveolar bone may become generalized but
remains less pronounced in the premolar areas.
33. Trauma from Occlusion
Traumatic lesions manifest more clearly in faciolingual aspects because
mesiodistally, the tooth has the added stability provided by the contact areas
with adjacent teeth. Therefore slight variations in the proximal surfaces may
indicate greater changes in the facial and lingual aspects.
34. The injury phase of trauma from occlusion produces a loss of the lamina dura
that may be noted in apices, furcations, and marginal areas. This loss of
lamina dura results in widening of the PDL space.
The repair phase of trauma from occlusion results in an attempt to strengthen
the periodontal structures to better support the increased loads.
Radiographically, this is manifested by a widening of the PDL space, which
may be generalized or localized.
35. More advanced traumatic lesions may result in deep angular bone loss, which,
when combined with marginal inflammation, may lead to intrabony pocket
formation.
In terminal stages, these lesions extend around the root apex, producing a
wide, radiolucent periapical image (cavernous lesions).
36. Digital imaging
In addition to the image manipulation features, digital radiographic images
facilitate patient education, allow for easy storage, and sharing with other
healthcare providers, and can be easily integrated into electronic patient
records.
37. CBCT
As discussed earlier, periapical and bite-wing radiographs provide information
mostly for the interdental bone.
However, a three-wall defect that preserves the buccal and/or lingual
cortices can be difficult to diagnose, and the buccal, lingual, and furcational
periodontal bone levels are hard to evaluate in conventional radiographs.
When clinical examination raises concerns for such areas, CBCT imaging can
add diagnostic value