Pulmonary Medicine is a branch of medicine that deals with respiratory diseases, chest wall diseases, sleep disorders, allergy and much more. This presentation describes this specialty branch in detail with scope and current perspectives being emphasized. It will help in PG aspirant medicos, academicians and undergraduate students to know about Pulmonary Medicine in detail.
Apparently a lengthy presentation actually very good for junior physicians as it covers all aspects of assessment, diagnosis and treatment of pleural effusion
Apparently a lengthy presentation actually very good for junior physicians as it covers all aspects of assessment, diagnosis and treatment of pleural effusion
Interstitial lung disease is a general category that includes many different lung conditions. All interstitial lung diseases affect the interstitium, a part of the lungs' anatomic structure.
Some of the types of interstitial lung disease include:
Interstitial pneumonia: Bacteria, viruses, or fungi may infect the interstitium of the lung. A bacterium called Mycoplasma pneumonia is the most common cause.
Idiopathic pulmonary fibrosis : A chronic, progressive form of fibrosis (scarring) of the interstitium. Its cause is unknown.
Nonspecific interstitial pneumonitis: Interstitial lung disease that's often present with autoimmune conditions (such as rheumatoid arthritis or scleroderma).
Interstitial lung disease is a general category that includes many different lung conditions. All interstitial lung diseases affect the interstitium, a part of the lungs' anatomic structure.
Some of the types of interstitial lung disease include:
Interstitial pneumonia: Bacteria, viruses, or fungi may infect the interstitium of the lung. A bacterium called Mycoplasma pneumonia is the most common cause.
Idiopathic pulmonary fibrosis : A chronic, progressive form of fibrosis (scarring) of the interstitium. Its cause is unknown.
Nonspecific interstitial pneumonitis: Interstitial lung disease that's often present with autoimmune conditions (such as rheumatoid arthritis or scleroderma).
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Successful career planning for secondary school students lessons from the me...Ahmed Elshebiny
If you are a secondary school student willing to learn more about successful career planning and more about the medical career, this presentation might help.
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Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
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Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
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Pulmonary medicine- Scope and Future by Dr. Jebin Abraham, MD.
1. Pulmonary Medicine
Scope & Future
An Indian Perspective
Dr. Jebin Abraham MD
Department of Pulmonary Medicine
Government Medical College Patiala
2. Preface
This article is emphasising Pulmonary Medicine as a specialty branch.
A guide to medical undergraduates, PG asprants and postgraduate
students.
Current and future perspectives of Pulmonary Medicine is explored in
Indian medical scenario.
2
3. Introduction
Pulmonary Medicine deals with diseases of lungs, airways, chest wall,
sleep disorders as well as allergy.
It is an evolving medical branch with advanced subspecialties.
Also Known as
Respiratory Medicine
Chest diseases and Tuberculosis
3
4. Introduction
Initially started as a specialty branch to deal with tuberculosis, the age old
menace in Indian community.
Apart from tuberculosis, it deals with all sorts of respiratory diseases and
provides expertise in various diagnostic and therapeutic procedures.
Currently being recognized as a super-specialty branch.
Available degrees/diplomas: MD, DNB, DTCD, DM
Seats are limited compared to General Medicine and Paediatrics.
4
5. Do you fit for Pulmo?
Do you wish to be a physician?
Do you want end-specialty (more or less)?
Do you wish to avoid heavy duties?
Do you wish to spend enough time with your family?
Do you wish to avoid medico-legal issues?
Do you like minor surgeries?
Do you wish to use a Bronchoscope/ Thoracoscope?
Well, go for Pulmonary Medicine.
5
6. If you want to work like a super-specialist but not ready to spend 3 more
years in study…
If you want to be a physician but not ready to have a hectic PG life…
If you want an end specialty but not interested to have a ‘do or die’
struggle in PG entrance test…
Then, go for Pulmonary Medicine.
6
11. Sub-specialties
If you wish to explore further after MD/DNB Pulmo, you may go for
fellowship/training/diploma for various sub-specialties:
Allergy and Asthma
Sleep Medicine
ICU and Critical care
Interventional Pulmonology
Medical Research
11
12. What after MD?
Start your own clinical practice
Join as Medical College faculty
Join for DM - Reach the top of specialty
Concentrate on any of sub-specialties
Do research and contribute to science
12
13. Courses after MD
DM in Pulmonology, Critical care, Cardiology, Infectious disease
Fellowships/Diploma in Sleep Medicine (FSM), Intensive care (IDCCM),
Allergy and Asthma (DAA), Interventional Pulmonology etc
Others: Thoracic oncology, Paediatric pulmonology, Public health
Also FCCP, FIAB, FNCCP etc.. etc..
Training Courses/ Workshops: EBUS, Thoracoscopy, Interventional
Pulmonology, ICU Management, Mechanical Ventilation, Allergy testing
and Immunotherapy, Sleep Medicine, Thoracic ultrasound etc.
13
14. Allergy and Asthma
Most demanding specialty
Yet under-explored area
Easy practice
Low infrastructure requirement
Good outcome
After all, just look around for an allergist…. Do you find anyone?
If no, then why shouldn’t you place yourself there?
14
15. Sleep Medicine
A growing specialty
Under-explored in India
Demand increasing rapidly
Life-style diseases and sleep disorders are raising together in India
No substitute for a sleep physician
15
16. ICU and Critical care
Pros
Every good hospital requires intensivists: Good scope
Fellowships and diplomas available
Good earnings
No long term responsibilities
Highly skilled area
Cons
Heavy duties
Rapid decision making
No social life
Poor long term doctor-patient relationships
16
17. Interventional Pulmonology
Pros
Highly skilled specialty
Less competition
Professional competency and satisfaction
Good earning
Cons
High infrastructure setups
Sturdy training
17
18. Medical Education & Research
Pros
Contributing to Medical Science
High position in medical society
Top academic position
Draft national and international guidelines
Work with international societies, eg WHO
Teach upcoming generation of doctors
Cons
Slow career growth
Low initial financial benefit
Government restrictions on private practice
18
19. General Medicine Vs Pulmonary
Medicine
General Medicine
Pros
Enables you to diagnose and treat a variety of systemic diseases.
Vast diagnostic check ups and diverse case scenarios.
Able to provide basic medical support to all age groups.
Independent practice possible
Can adapt to small and large hospitals
Cons
Trend of super-specialty seeking is increasing
Tight competition among peers
Require referral to super-specialty sections often
Do not promise deep knowledge about any single system
19
20. General Medicine Vs Pulmonary
Medicine
Pulmonary Medicine
Pros
Deep knowledge about subject ( At least, textbook Fishman (Pulmo) is
heavier than Harrison’s !)
Super-specialist care at specialist level (eg. Bronchoscopy and
Thoracoscopy)
No hectic duties
Equal pay
Limited but relevant cases
Able to provide critical care
Highly skilled procedures like EBUS-TBNA and other interventions
20
21. General Medicine Vs Pulmonary
Medicine
Pulmonary Medicine
Cons
Lack of training in internal medicine
Possible difficulty in managing multi-systemic diseases
Risk of occupational hazard- MDR TB and Viral infections
Lack of popularity of branch among public
Lack of specialist post/vacancy: Many govt as well as private hospitals does
not accommodate separate pulmo dept.
21
22. MD Vs DNB
Both are well recognized.
MD is more popular than DNB among public.
Medical colleges offer more academics than private hospitals (Of course,
there are exceptions!)
MD holder can appear for DNB exam and obtain an additional degree
MD course provide better research facilities
DNB course provide better exposure to latest equipment and advanced
treatment options
MD has higher case load
MD holder can directly enter medical education services
22
23. Scope of DM Pulmonology
Opportunity to become pioneers in the specialty
Less number of seats
Work experience from top rated institutes
Opportunity to try out most recent advances in the field
Good professional skills and gains
A step to become recognized international level faculty
23
24. Scope of Pulmonary Medicine in
General Practice
Well… What is the most common symptom with which patients come to
general OPD?
Yeah….. Its Cough!!
24
25. Important facts
Your attitude matters more than your skills, whatever be your degree.
Success depends on how you define it, not simply on your bank balance.
Select a good institute to join. DNB from a good institute might be practically
more valuable than MD from a bad institute.
Give importance to your personal and family life while opting for a college far
away from your home. And of course, language and food!
Be aware about current status of bond.
Try to contact current PG students working in the institute you wish to join.
Enquire about the duties, academics, casual leaves etc. Be sure that your future
Head should not be a ‘head eater’!
25
26. An Ideal Training Institute
Spirometry
Body Plethysmography
DLCO
Basic Bronchoscopy Suite (BAL, TBLB, TBNA)
Thoracoscopy
Sleep Lab
Respiratory ICU
Non invasive Ventilation
Mechanical Ventilation
26
27. An Ideal Training Institute
Preferable to have:
Higher number of recognized PG seats
Good patient load
Specialty posting in other departments
Good stipend and No bond
Night duty offs
More Casual leaves
Academic programs: Seminars, Journal Clubs, Bed-side Clinics, Conferences,
Workshops
After all, you need a good HOD and Unit Head!
Enquire about all these things before you opt in.
27
28. FAQ
Q) I wanted General Medicine. But my rank is not good enough to get
it. Shall I take one more chance or opt for Pulmonary Medicine?
Well, you might have got the answer by now. Number of PG aspirants are
exponentially increasing every year. So definitely you need to improve your
efficiency in next attempt. Getting a better rank depends on your
commitment and smart work (? Hard work). Nothing is impossible. But be
intelligent in taking decisions. Your entire career depends on what you
choose.
28
29. FAQ
Q) Is there a risk of acquiring TB while doing PG in Pulmonary Medicine?
Yes, definitely a risk is there. But this risk is there for every doctor. Before a TB
patient present to a pulmonologist, he would have consulted at least one
general practitioner for his cough. So who is at higher risk?
Being a chest physician, you will be trained how to protect yourself from TB by
simple precautions and believe me, you will be suspecting TB in every possible
patient.
TB is a curable disease.
Surgeons are at risk of HIV/HCV. Won’t they do surgeries? Risks are there
everywhere.
Residents in Surgery, Medicine and even Gyne do get TB. Why? Stress and
workload, dietary habits and lack of precautions.
29
30. FAQ
Q) MD Pulmonary medicine and MD TB & Chest… Are they same?
Yes. TB and Chest was old name of the degree, and still frequently used in
north India. However, most of the universities are awarding the degree as
MD Pulmonary Medicine.
30
31. FAQ
Q) Can I confidently work in ICU/Critical care after doing MD Pulmo?
It depends purely on your training. If you take degree from a good institute
where you are getting exposure in ICU care, you may straight away work in ICU
after your course.
However, majority of colleges offer only respiratory ICU training, if at all; Many
lack ICU also.
You may undergo short term training in any good institute for critical care.
Or, do courses like IDCCM or fellowships which are getting good opportunities
currently.
Or, go for DM.
31
32. FAQ
Q) What is the scope of MD/DNB outside India?
Good scope, as similar to other medical branches.
Recognition of degree depends on individual country’s policies.
One can seek relevant fellowships in foreign countries as well.
32
33. FAQ
Q) Which are the recommended textbooks for Pulmonary Medicine?
You have to follow one standard textbook throughout your course. But you
have to depend on other books also for reading selected topics.
Well, I will go for Fishman. It is vast and authentic. But not an exam friendly
style. Make notes while reading Fishman. This book will teach you concepts.
High yield topics : Sleep and disorder, Lung and other systems, ILD, Respiratory failure,
Oxygen therapy, Diagnostics, Occupational diseases, Cancer basics & Obstructive airway
diseases.
Murray and Nadal: Standard textbook. Can be considered as alternative to
Fishman. Selected topics may be read from Murray even when following
Fishman.
33
34. FAQ
Crofton: Basic topics (Eg- Bronchiectasis) are well explained. But not an
updated book for advanced topics. So selective reading is advised.
SK Jindal: Student friendly, exam oriented, Indian authored book, vast
coverage including critical care.
High yield topics : All topics (leftover) can be quickly read is the biggest
advantage, Sepsis , Critical care & Aging.
Washington Manual of Pulmo Med: Pocket book, good for fast reading.
Not all topics included.
Lights (Pleural diseases): Must read, basic textbook
High yield topics : Physiology , Transudative PE, Tubercular, Parapneumonic PE,
Malignant PE, Pleural Malignancy, Hemo/Pneumo/ChyloThorax
34
35. FAQ
Zumla: Standard textbook for TB
High yield topics : General and Basic TB (TB pathogenesis , HIV and TB)
Sharma and Mohan: Good for TB, Alternative to Zumla
High yield topics : NTM, Systemic tuberculosis
Tomans: Must read book for TB
High yield topics :TB basics (diagnostic and treatment basics)
Pulmonary/Respiratory therapy Secrets: A must read book during PG
35
36. FAQ
Felson (Chest Roentgenology): Extensive coverage of Chest X Ray. Not for
exam oriented reading.
CXR- Survival guide: For exam oriented reading.
Webb (HRCT): Good one.
West : High yield for pulmonary physiology
Handbooks on ECG, Spirometry etc
Hutchison/Mcleods: Standard clinical examination texts, to learn how to
examine a patient
Alagappan/Golwala/Baburaj: For clinical viva and DDs
Kundu: For case discussion
CMDT/Harrison: To keep in touch with other systems. They give edge in
competitive exams
36
37. FAQ
Interesting reads (add on):
ICU book : Paul Marino
Ventilator : Chang
Bronchoscopy book
Allergy: Middleton’s
37
38. Journals to subscribe
An extensive list of journals are available on Respiratory Medicine.
Most of them provides E mail subscriptions free of cost.
Some Journals:
Chest, Thorax, Lancet, European respiratory journal, AJRCC etc.
Indian: Lung India, Indian Journal of Tuberculosis, Indian Journal of
Chest Diseases and Allied Sciences, Indian Journal of Allergy Asthma and
Immunology etc.
A list of top journals are available at:
https://www.scimagojr.com/journalrank.php?category=2740
38
39. Practice Guidelines
TB : TOG -2016, 2019 updates ; PMDT-2017, BDQ/DLM-2018 , INDEX TB
ILD: 2011/2018 IPF
CA: NCCN 2018
Asthma: GINA 2019 ( and changes from last guidelines)
COPD: GOLD 2019 ( and changes from last guidelines)
Spirometry guidelines 2019 (Indian)
CAP / HAP – Indian guidelines -2011
Survival Sepsis Campaign 2018
BTS guidelines for Inhaler use and Bronchoscopy.
39
40. Major Conferences
Chest Annual Meeting
ERS Annual Meeting
ATS Annual Meeting
NAPCON
NATCON
BRONCHOCON
ICAAICON
Pulmonary Medicine Updates
40
41. FAQ
Q) Can/ Shall I join any professional organizations while doing PG?
Yes. You can join various medical and specialty organizations and enhance
your professional network.
ACCP, ERS, Indian Chest Society, NCCP etc are some of the professional
networks.
IMA membership is also helpful in career.
41
42. FAQ
Q) How to become FCCP?
FCCP is a honorary fellowship, which requires specified criteria as explained
in ACCP website. For that you need to be a member of ACCP at least for 2
years, along with other professional contributions and recommendations.
ACCP membership is open to PG students also. So you can apply for it
soon after joining your PG and later for FCCP.
42
43. Selecting A Thesis Topic
Thesis is a scientific research work done under careful supervision of senior
faculty of the department.
Novel topics are always highly recommended, however execution of the
research work should be prime concern (Just think whether you will be
able to perform the work under your current circumstances with available
resources).
Think twice while selecting dynamic topics (Those which might be
influenced by changing health policies or guidelines in coming years: It
might reduce relevance of your research at the time of publication, Eg-
RNTCP Category 2.
Even if you get no positive correlation or statistical significance, your study
will be scientifically significant, if done in proper way.
43
44. Selecting A Thesis Topic
So, while selecting a topic, consider these points
Is it a relevant topic?
Will it contribute something new to science?
Do you have the necessary facilities in your department?
Will you get enough support from your department?
Do your supervisor completely agree for this project?
Is there a concern of financial needs?
Will you get support from other departments (If your requires)?
Will you get ethics committee approval?
44
45. Selecting A Thesis Topic
Repeating a topic already done many times will make it easy for you as
you can get help from previously done thesis works.
However, on a scientific aspect, it would not help you in career growth.
Doing thesis on a new subject is interesting and challenging. However,
your resources will be limited. But, results will be rewarding.
Make sure that topic is cost effective for your patients and meet ethical
standards (Get help from supervisor).
Cross sectional and retrospective studies are easy to perform. However,
their research value is low while getting published.
45
46. Selecting A Thesis Topic
Interventional studies and clinical trials are difficult to carry out. However,
they have high research value.
Go through national conference booklets (NAPCON, NATCON) and
journals for current trending topics.
Make sure your topic abides university rules (Like, it should not have been
conducted in previous 5 yrs in your college/ university etc).
Try to obtain grants/ financial assistance available for young researchers.
46
47. Selecting A Thesis Topic
Pre-plan how you will construct your master-chart and what all parameters
will be taken for stats (It will help you later!): Get help from seniors.
Conduct parallel researches along with thesis on related/extended topic: It
can help you to furnish an extra paper.
Finish the thesis work during initial months of final year and get enough
time for exam preparation.
Present your paper in National / International conference and publish it in
peer reviewed indexed journals.
47
48. Case Presentation Proforma for
Respiratory System
Available at: https://dx.doi.org/10.13140/RG.2.2.25781.22243
48