Presentation given by John Uhlrich, editor of the journal Energy Technology at Wiley-VCH, on a visit to Friedrich-Schiller-University Jena, 5th of October 2016.
Publishing Scientific Research and How to Write High-Impact Research Papersjjuhlrich
Presentation given by John Uhlrich, as the Editor-in-Chief of Energy Technology at Wiley-VCH, at Lawrence Berkeley National Laboratory on November 18, 2016.
What Do Editors Do All Day? From Science to Publishing.jjuhlrich
Presentation by John Uhlrich, the Editor-in-Chief of the journal Energy Technology at Wiley-VCH publishing, at the International Max Planck Research School (IMPRS) at Ringberg Castle on February 22, 2018 as a snapshot of what editors do and a few current challenges in the publishing industry.
Publishing Scientific Research and How to Write High-Impact Research Papersjjuhlrich
Presentation on how to publish high-impact scientific papers by John Uhlrich, Editor-in-Chief of the journal Energy Technology, published by Wiley-VCH.
Publishing Scientific Research & How to Write High-Impact Research Papersjjuhlrich
Presentation on publishing scientific research and how to write high-impact scientific papers by Dr. John Uhlrich as the Editor-in-Chief of Energy Technology published by Wiley-VCH, given on 25 October 2018 at the National Energy Technology Laboratory, USA.
Publishing Scientific Research & How to Write High-Impact Research Papersjjuhlrich
Presentation on publishing scientific research and how to write high-impact scientific papers by Dr. John Uhlrich as the Editor-in-Chief of Energy Technology published by Wiley-VCH, given on 25 October 2018 at the University of Pittsburgh, USA.
Wiley-VCH Mathero Summer School Presentation-John Uhlrichjjuhlrich
Tips on the publication process and how to write successful scientific papers, given for PhD students in the physical sciences at the Mathero Summer School.
Freudenberg, Germany
26 August 2015
Publishing Scientific Research and How to Write High-Impact Research Papersjjuhlrich
Presentation given by John Uhlrich, as the Editor-in-Chief of Energy Technology at Wiley-VCH, at Lawrence Berkeley National Laboratory on November 18, 2016.
What Do Editors Do All Day? From Science to Publishing.jjuhlrich
Presentation by John Uhlrich, the Editor-in-Chief of the journal Energy Technology at Wiley-VCH publishing, at the International Max Planck Research School (IMPRS) at Ringberg Castle on February 22, 2018 as a snapshot of what editors do and a few current challenges in the publishing industry.
Publishing Scientific Research and How to Write High-Impact Research Papersjjuhlrich
Presentation on how to publish high-impact scientific papers by John Uhlrich, Editor-in-Chief of the journal Energy Technology, published by Wiley-VCH.
Publishing Scientific Research & How to Write High-Impact Research Papersjjuhlrich
Presentation on publishing scientific research and how to write high-impact scientific papers by Dr. John Uhlrich as the Editor-in-Chief of Energy Technology published by Wiley-VCH, given on 25 October 2018 at the National Energy Technology Laboratory, USA.
Publishing Scientific Research & How to Write High-Impact Research Papersjjuhlrich
Presentation on publishing scientific research and how to write high-impact scientific papers by Dr. John Uhlrich as the Editor-in-Chief of Energy Technology published by Wiley-VCH, given on 25 October 2018 at the University of Pittsburgh, USA.
Wiley-VCH Mathero Summer School Presentation-John Uhlrichjjuhlrich
Tips on the publication process and how to write successful scientific papers, given for PhD students in the physical sciences at the Mathero Summer School.
Freudenberg, Germany
26 August 2015
Publishing Scientific Research and How to Write High-Impact Research Papersjjuhlrich
Invited presentation by John Uhlrich as Editor-in-Chief of the scientific journal Energy Technology published by Wiley-VCH, given at King Abdullah University of Science and Technology on 29 January 2017.
Publishing Scientific Research and How to Write High-Impact Research Papersjjuhlrich
Presentation given on 16 June 2017 by John Uhlrich, as Editor-in-Chief of the journal Energy Technology published by Wiley-VCH, on how to write high-impact research papers from the editorial perspective.
Changing landscape of the publishing world - NUS Singapore 2015Martijn Roelandse
In this fast-paced world, there are many different factors which affect the landscape of the academic publishing world. During my talk at NUS in Singapore I tried to outline these significant factors and their impact on research.
Outline
• Pressure on Reviewers
• Open Access
• Author Focus
• The Measurement of "Quality"
• Bookmetrix
• Big Data
Academic social networking allows you to connect with other researchers in your field, share your publications and datasets, get feedback on your non-peer-reviewed work, and to stay current with news and events in your field of interest. It gives you another place to establish your name and research and perhaps even collaborate with others. The academic, social networking, making your work more widely discoverable and easily available. LinkedIn (launched in 2003) is currently the third most popular social network in terms of unique monthly visitors, right behind Facebook and Twitter. The LinkedIn is primarily centered around careers, and it enables users to connect and share content with other professionals. In addition, it is an online CV and as a place to share your publications.
A researcher impact, may measure by number of publications and counting the number of times it has been cited by other scholars. A recent study discovered that over 43% of ISI papers have never ever received any citations (nature.com/top100, 2014). Now it’s time to start spreading the word around your findings and analysis. Publishing a high quality paper in scientific journals is only halfway towards receiving citation in the future. The rest of the journey is dependent on disseminating the publications via using the proper “Research Tools”. Proper utilization of the tools allows the researchers to increase the research impact and citations for their publications. This workshop provides some techniques to increase the visibility and hence the impact of your research work.
A new research impact measuring system by nader ale ebrahimNader Ale Ebrahim
For years, scientists have been trying to measure the quality of scholarly work by the number of times an article is cited in other articles or the impact factor of the journal which published an article. However, citation is a lagging indicator and journal impact factor may be misleading since a Journal's citation count is usually caused by a small number of articles in that journal.
With the rise of the web as the archiving and emerging interaction platform, there is a need for new ways to measure articles and books impact. Altmetrics attempts to use the online activity to measure impact, buzz, word of mouth for scientific information and it includes new ways to measure usage at the citation level. In this workshop, I will explain about application of altmetrics tools such as: Altmetric.com, Impactstory.org, Plumanalytics.com, and PLoS metrics.
This presentation is a summary of the following presentations on “Conducting a Literature Search & Writing Review Paper”:
Part 1: Systematic Review https://dx.doi.org/10.6084/m9.figshare.1100235.v1
Part 2: Finding proper articles https://dx.doi.org/10.6084/m9.figshare.1100242.v1
Part 3: Writing Literature Review https://dx.doi.org/10.6084/m9.figshare.1100256.v1
Part 4: Paper submission & dissemination https://dx.doi.org/10.6084/m9.figshare.1100257.v1
Selecting a research “brand name” is one of the most important decisions that a researcher will need to make. The research brand name should appear in the title, abstract and keywords of the paper. The title is extremely important and must be chosen with great care, as it will be read by thousands, whereas few will read the entire paper. On the other hand, indexing and abstracting of the paper depends on the accuracy of the title. An improperly titled paper will get lost and will never be read. The unique research name makes title meaningful and not general.
Prepare a pre/post print of your documents for advertisementNader Ale Ebrahim
With overwhelming thousands of online journals daily, many scholarly articles simply never reach their intended audience and consequently fail to generate the impact they deserve. Traditionally, scholarly publishers ensured the visibility of an authors’ work by circulating print journals to targeted readers. But fewer people are reading print journals anymore and as content continues to migrate from print to online — how can researchers optimize electronic distribution of content? This presentation, lead you to prepare a pre/post print of your documents for online presence and advertisement.
Bibliometrics can be defined as the statistical analysis of publications. Bibliometrics has focused on the quantitative analysis of citations and citation counts which is complex. It is so complex and specialized that personal knowledge and experience are insufficient for understanding trends and then making decisions. We need tools for analysis of bibliometrics information to recognize the research trends and evaluate scientific/institution/country’s research productivity. This presentation will provide procedure to write a Bibliometrics paper.
This ppt will provide the support to finding the indexing of publication and also will help to manage your research profile among world research forums.
Elsevier social media for researchers - University of Balamanduoblibraries
Workshop on Elsevier social media for researchers - Oct 18, 2018 - Issam Fares Library Learning Center - University of Balamand - by Ms. Ozge Sertdemir,Customer Consultant - Elsevier RSS
Publishing Scientific Research and How to Write High-Impact Research Papersjjuhlrich
Invited presentation by John Uhlrich as Editor-in-Chief of the scientific journal Energy Technology published by Wiley-VCH, given at King Abdullah University of Science and Technology on 29 January 2017.
Publishing Scientific Research and How to Write High-Impact Research Papersjjuhlrich
Presentation given on 16 June 2017 by John Uhlrich, as Editor-in-Chief of the journal Energy Technology published by Wiley-VCH, on how to write high-impact research papers from the editorial perspective.
Changing landscape of the publishing world - NUS Singapore 2015Martijn Roelandse
In this fast-paced world, there are many different factors which affect the landscape of the academic publishing world. During my talk at NUS in Singapore I tried to outline these significant factors and their impact on research.
Outline
• Pressure on Reviewers
• Open Access
• Author Focus
• The Measurement of "Quality"
• Bookmetrix
• Big Data
Academic social networking allows you to connect with other researchers in your field, share your publications and datasets, get feedback on your non-peer-reviewed work, and to stay current with news and events in your field of interest. It gives you another place to establish your name and research and perhaps even collaborate with others. The academic, social networking, making your work more widely discoverable and easily available. LinkedIn (launched in 2003) is currently the third most popular social network in terms of unique monthly visitors, right behind Facebook and Twitter. The LinkedIn is primarily centered around careers, and it enables users to connect and share content with other professionals. In addition, it is an online CV and as a place to share your publications.
A researcher impact, may measure by number of publications and counting the number of times it has been cited by other scholars. A recent study discovered that over 43% of ISI papers have never ever received any citations (nature.com/top100, 2014). Now it’s time to start spreading the word around your findings and analysis. Publishing a high quality paper in scientific journals is only halfway towards receiving citation in the future. The rest of the journey is dependent on disseminating the publications via using the proper “Research Tools”. Proper utilization of the tools allows the researchers to increase the research impact and citations for their publications. This workshop provides some techniques to increase the visibility and hence the impact of your research work.
A new research impact measuring system by nader ale ebrahimNader Ale Ebrahim
For years, scientists have been trying to measure the quality of scholarly work by the number of times an article is cited in other articles or the impact factor of the journal which published an article. However, citation is a lagging indicator and journal impact factor may be misleading since a Journal's citation count is usually caused by a small number of articles in that journal.
With the rise of the web as the archiving and emerging interaction platform, there is a need for new ways to measure articles and books impact. Altmetrics attempts to use the online activity to measure impact, buzz, word of mouth for scientific information and it includes new ways to measure usage at the citation level. In this workshop, I will explain about application of altmetrics tools such as: Altmetric.com, Impactstory.org, Plumanalytics.com, and PLoS metrics.
This presentation is a summary of the following presentations on “Conducting a Literature Search & Writing Review Paper”:
Part 1: Systematic Review https://dx.doi.org/10.6084/m9.figshare.1100235.v1
Part 2: Finding proper articles https://dx.doi.org/10.6084/m9.figshare.1100242.v1
Part 3: Writing Literature Review https://dx.doi.org/10.6084/m9.figshare.1100256.v1
Part 4: Paper submission & dissemination https://dx.doi.org/10.6084/m9.figshare.1100257.v1
Selecting a research “brand name” is one of the most important decisions that a researcher will need to make. The research brand name should appear in the title, abstract and keywords of the paper. The title is extremely important and must be chosen with great care, as it will be read by thousands, whereas few will read the entire paper. On the other hand, indexing and abstracting of the paper depends on the accuracy of the title. An improperly titled paper will get lost and will never be read. The unique research name makes title meaningful and not general.
Prepare a pre/post print of your documents for advertisementNader Ale Ebrahim
With overwhelming thousands of online journals daily, many scholarly articles simply never reach their intended audience and consequently fail to generate the impact they deserve. Traditionally, scholarly publishers ensured the visibility of an authors’ work by circulating print journals to targeted readers. But fewer people are reading print journals anymore and as content continues to migrate from print to online — how can researchers optimize electronic distribution of content? This presentation, lead you to prepare a pre/post print of your documents for online presence and advertisement.
Bibliometrics can be defined as the statistical analysis of publications. Bibliometrics has focused on the quantitative analysis of citations and citation counts which is complex. It is so complex and specialized that personal knowledge and experience are insufficient for understanding trends and then making decisions. We need tools for analysis of bibliometrics information to recognize the research trends and evaluate scientific/institution/country’s research productivity. This presentation will provide procedure to write a Bibliometrics paper.
This ppt will provide the support to finding the indexing of publication and also will help to manage your research profile among world research forums.
Elsevier social media for researchers - University of Balamanduoblibraries
Workshop on Elsevier social media for researchers - Oct 18, 2018 - Issam Fares Library Learning Center - University of Balamand - by Ms. Ozge Sertdemir,Customer Consultant - Elsevier RSS
Presentation by Todd Carpenter during the Project Muse Publishers meeting in Baltimore, MD on April 24, 2014. During this talk, Todd discussed standards related to scholarly publishing and the output of several NISO initiatives.
Wiley’s 2013 open access survey was deployed in May 2013 to 107,000 corresponding authors of Wiley journal articles. Key findings include:
• The number of open access authors has grown significantly.
• Quality and profile of open access publications remains a concern.
• There are indications of author confusion around funder mandates.
• Respondents overwhelmingly preferred the more permissive licenses.
• Considerable differences emerge between early career professionals and more established colleagues when comparing funding and payments for APCs.
For more information, please visit http://exchanges.wiley.com/blog
Connect with us:
http://twitter.com/WileyExchanges
http://twitter.com/WileyOpenAccess
Publishing Scientific Research & How to Write High-Impact Research Papersjjuhlrich
Presentation on publishing scientific research and how to write high-impact scientific papers by Dr. John Uhlrich as the Editor-in-Chief of Energy Technology published by Wiley-VCH, given on 02 November 2018 at the Wilton E. Scott Institute for Energy Innovation at Carnegie Mellon University, USA.
Publishing Scientific Research & How to Write High-Impact Research Papersjjuhlrich
Presentation on publishing scientific research and how to write high-impact scientific papers by Dr. John Uhlrich as the Editor-in-Chief of Energy Technology published by Wiley-VCH, given on 03 October 2018 at the EPFL campus in Sion.
Publishing Scientific Research & How to Write High-Impact Research Papersjjuhlrich
Presentation on publishing scientific research and how to write high-impact scientific papers by Dr. John Uhlrich as the Editor-in-Chief of Energy Technology and Dr. Esther Levy, the Editor-in-Chief of Advanced Materials Technologies, both published by Wiley-VCH. Slide were presented on 28 June 2019 at the Singapore University of Technology and Design (SUTD).
Publishing Scientific Research & How to Write High-Impact Research Papersjjuhlrich
Presentation on publishing scientific research and how to write high-impact scientific papers by Dr. John Uhlrich as the Editor-in-Chief of Energy Technology, published by Wiley-VCH. Slides were presented on 25 November 2019 at the Techical University of Darmstadt.
Publishing Scientific Research & How to Write High-Impact Research Papersjjuhlrich
Presentation on publishing scientific research and how to write high-impact scientific papers by Dr. John Uhlrich as the Editor-in-Chief of Energy Technology, published by Wiley-VCH. Slides were presented on 29 July 2019 at the Helmholtz Institute Ulm (HIU).
Publishing Scientific Research & How to Write High-Impact Research Papersjjuhlrich
Presentation on publishing scientific research and how to write high-impact scientific papers by Dr. John Uhlrich as the Editor-in-Chief of Energy Technology, published by Wiley-VCH. Slides were presented on 04 July 2019 at the Karlsruhe Institute of Technology (KIT) energy center.
Publishing Scientific Research & How to Write High-Impact Research Papers jjuhlrich
Presentation on publishing scientific research and how to write high-impact scientific papers by Dr. John Uhlrich as the Editor-in-Chief of Energy Technology, published by Wiley-VCH. Slides were presented on 07 December 2021 virtually for the Institute of Materials Research and Engineering (IMRE) at A*Star, Singapore.
Publishing Scientific Research & How to Write High-Impact Research Papersjjuhlrich
Presentation on publishing scientific research and how to write high-impact scientific papers by Dr. John Uhlrich as the Editor-in-Chief of Energy Technology, published by Wiley-VCH. Slides were presented on 17 February 2020 at the Technical University of Braunschweig.
Publishing Scientific Research & How to Write High-Impact Research Papersjjuhlrich
Presentation on publishing scientific research and how to write high-impact scientific papers by Dr. John Uhlrich as the Editor-in-Chief of Energy Technology, published by Wiley-VCH. Slides were presented on 07 February 2020 at Justus-Liebig-Universität Gießen.
Publishing Scientific Research and How to Write High-Impact Research Papersjjuhlrich
Presentation on publishing scientific research and how to write high-impact scientific papers by Dr. John Uhlrich as the Editor-in-Chief of Energy Technology, published by Wiley-VCH. Slides were presented on 27 October 2020 virtually for the SFB/TRR 270 Meeting of PhD students from the Technical University Darmstadt and University of Duisburg-Essen.
'Understanding and benefiting from the publishing process'
Publishing Connect workshop Lancaster delivered by Anthony Newman, Senior Publisher, Elsevier.
Types of scientific publications
The different types of research papers published
Considerations before writing
Choosing the right journal
Writing using correct language
The structure of the manuscript
The submission and review procedure
Author responsibilities: publishing ethics and plagiarism
How to use information resources as a tool for authors (Scopus)
Slides shared with the permission of the speaker.
Research Tools: Choosing the Right Journal for Your ResearchNader Ale Ebrahim
“Research Tools” can be defined as vehicles that broadly facilitate research and related activities. Scientific tools enable researchers to collect, organize, analyze, visualize and publicized research outputs. Dr. Nader has collected over 700 tools that enable students to follow the correct path in research and to ultimately produce high-quality research outputs with more accuracy and efficiency. It is assembled as an interactive Web-based mind map, titled “Research Tools”, which is updated periodically. “Research Tools” consists of a hierarchical set of nodes. It has four main nodes: (1) Searching the literature, (2) Writing a paper, (3) Targeting suitable journals, and (4) Enhancing visibility and impact of the research. Several free tools can be found in the child nodes. In this workshop some tools as examples from the part 3 (Targeting suitable journals) will be described. The e-skills learned from the workshop are useful across various research disciplines and research institutions.
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
Comparing Evolved Extractive Text Summary Scores of Bidirectional Encoder Rep...University of Maribor
Slides from:
11th International Conference on Electrical, Electronics and Computer Engineering (IcETRAN), Niš, 3-6 June 2024
Track: Artificial Intelligence
https://www.etran.rs/2024/en/home-english/
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...Sérgio Sacani
Since volcanic activity was first discovered on Io from Voyager images in 1979, changes
on Io’s surface have been monitored from both spacecraft and ground-based telescopes.
Here, we present the highest spatial resolution images of Io ever obtained from a groundbased telescope. These images, acquired by the SHARK-VIS instrument on the Large
Binocular Telescope, show evidence of a major resurfacing event on Io’s trailing hemisphere. When compared to the most recent spacecraft images, the SHARK-VIS images
show that a plume deposit from a powerful eruption at Pillan Patera has covered part
of the long-lived Pele plume deposit. Although this type of resurfacing event may be common on Io, few have been detected due to the rarity of spacecraft visits and the previously low spatial resolution available from Earth-based telescopes. The SHARK-VIS instrument ushers in a new era of high resolution imaging of Io’s surface using adaptive
optics at visible wavelengths.