This document discusses the Project GreenLight, which aims to minimize the energy consumption of cyberinfrastructure through instrumentation and measurement. It focuses on enabling more efficient computing options for key user communities like metagenomics and digital media. The project constructs an energy instrumented modular data center to house specialized computing clusters and measure their energy usage. It also explores direct DC power from solar/fuel cells and virtualization techniques to improve efficiency and reduce energy costs of computational science. The goals are to better understand optimization of work per watt and develop middleware to automate optimal power strategies.