The document outlines the objectives and procedures of a drug substitution therapy program for opioid dependent patients. The goals are to: 1) Improve health and quality of life by reducing relapse and improving physical and mental conditions through drug substitution therapy. 2) Reduce the spread of infections like HIV and hepatitis among intravenous drug users. 3) Improve psychosocial functioning and ability to gain employment. 4) Reduce criminal activities among opioid dependent individuals. The procedures include registration, screening, consent, initial assessment of health status, counseling, drug substitution therapy, evaluations, and follow-ups. Patients are reviewed regularly and given take-home doses based on urine test results and adherence to the program.