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Evidence-Based Management, an introduction
1.
2.
3.
4. Organiza%onal
facts,
metrics
and
characteris%cs
Prac%%oner
Best
available
scien%fic
exper%se,
reflec%on
Evidence-‐based
evidence
and
judgement
decision
Stakeholders’
values
and
concerns
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10. Peptic ulcer – an infectious disease!
This year's Nobel Prize in Physiology or Medicine goes to Barry Marshall and Robin
Warren, who with tenacity and a prepared mind challenged prevailing dogmas. By
using technologies generally available (fibre endoscopy, silver staining of
histological sections and culture techniques for microaerophilic bacteria), they
made an irrefutable case that the bacterium Helicobacter pylori is causing disease.
By culturing the bacteria they made them amenable to scientific study.
In 1982, when this bacterium was discovered by Marshall and Warren, stress and
lifestyle were considered the major causes of peptic ulcer disease. It is now
firmly established that Helicobacter pylori
causes more then 90% of duodenal ulcers.
The link between Helicobacter pylori
infection and peptic ulcer disease has been
established through studies of human
volunteers, antibiotic treatment studies and
epidemiological studies.
11.
12.
13.
14. Clinicians’ clinical
expertise
Evidence Decision
Patients’
preferences and
clinical state
51. A It is shown that …
B It is likely that …
C
There are signs
that …
D
Experts are of the
- opinion that …
52.
53.
54.
55.
56. Organiza%onal
facts,
metrics
and
characteris%cs
Prac%%oner
Best
available
scien%fic
exper%se,
reflec%on
Evidence-‐based
evidence
and
judgement
decision
Stakeholders’
values
and
concerns