Changes in the nucleotide sequence of DNA
May occur in somatic cells (aren’t passed to offspring)
May occur in gametes (eggs & sperm) and be passed to offspring
Changes in the nucleotide sequence of DNA
May occur in somatic cells (aren’t passed to offspring)
May occur in gametes (eggs & sperm) and be passed to offspring
Changes in the nucleotide sequence of DNA
May occur in somatic cells (aren’t passed to offspring)
May occur in gametes (eggs & sperm) and be passed to offspring
Mutations happen regularly
Almost all mutations are neutral
Chemicals & UV radiation cause mutations
Many mutations are repaired by enzymes
Some type of skin cancers and leukemia result from somatic mutations
Some mutations may improve an organism’s survival (beneficial)
chromosome mutations=
Five types exist:
Deletion
Inversion
Translocation
Nondisjunction
Duplication
mutation
history of mutation
classification of mutation
types of mutation
syndrome due to mutation
chromosomal variations in number
causes of mutation to occur
mutagen types
Changes in the nucleotide sequence of DNA
May occur in somatic cells (aren’t passed to offspring)
May occur in gametes (eggs & sperm) and be passed to offspring
Changes in the nucleotide sequence of DNA
May occur in somatic cells (aren’t passed to offspring)
May occur in gametes (eggs & sperm) and be passed to offspring
Changes in the nucleotide sequence of DNA
May occur in somatic cells (aren’t passed to offspring)
May occur in gametes (eggs & sperm) and be passed to offspring
Mutations happen regularly
Almost all mutations are neutral
Chemicals & UV radiation cause mutations
Many mutations are repaired by enzymes
Some type of skin cancers and leukemia result from somatic mutations
Some mutations may improve an organism’s survival (beneficial)
chromosome mutations=
Five types exist:
Deletion
Inversion
Translocation
Nondisjunction
Duplication
mutation
history of mutation
classification of mutation
types of mutation
syndrome due to mutation
chromosomal variations in number
causes of mutation to occur
mutagen types
Gene mutations – introduction – definition – a brief history – terminology –
classification of mutations – characteristic features of mutations – spontaneous
mutations and induced mutations
Gene mutations – artificial induction of mutations – physical and chemical
mutagens – molecular basis of mutations – detection of sex-linked lethals in
Drosophila by CLB technique – detection of mutations in plants – the importance of
mutation in plant breeding programmes –
Alterations in the DNA code, such as changing a letter, deleting a letter, inserting a letter or moving sections aroun proteins with abnormal functions.
If these abnormal functions cause the cell to grow, divide, ignore regulatory signals or assume new functions, cancers can develop
Fortunately, normal cells are good at repairing mistakes should they occur and have multiple systems for ensuring that the DNA co transmitted to its two daughter cells when it divides. Normal cells even have suicide programs if the mistakes are beyond repair, a p death, known as apoptosis. [Source: https://www.loxooncology.com/genomically-defined-cancers/genomic-alterations]
Gene mutations – introduction – definition – a brief history – terminology –
classification of mutations – characteristic features of mutations – spontaneous
mutations and induced mutations
Gene mutations – artificial induction of mutations – physical and chemical
mutagens – molecular basis of mutations – detection of sex-linked lethals in
Drosophila by CLB technique – detection of mutations in plants – the importance of
mutation in plant breeding programmes –
Alterations in the DNA code, such as changing a letter, deleting a letter, inserting a letter or moving sections aroun proteins with abnormal functions.
If these abnormal functions cause the cell to grow, divide, ignore regulatory signals or assume new functions, cancers can develop
Fortunately, normal cells are good at repairing mistakes should they occur and have multiple systems for ensuring that the DNA co transmitted to its two daughter cells when it divides. Normal cells even have suicide programs if the mistakes are beyond repair, a p death, known as apoptosis. [Source: https://www.loxooncology.com/genomically-defined-cancers/genomic-alterations]
Cell Biology and genetics paper - Mutation a basic touch to b.sc students with examples. DNA, genome, gene level mutation and chromosome level with examples. Touched some of the mutation types.
mutations Is a process that produces a gene or chromosome that differs from the wild type.
The mutation may result due to changes either on the gene or the chromosome itself.
An overview on mutation, the general mechanisms, classification based on various characteristics, analogy sentence and genetic disorder of various types based on its classification, a brief description of mutagens agents and consequences of mutation in our body and on other living creatures
4. The causes of mutations
1. DNA fails to copy accurately
Most of the mutations that we think matter to evolution are
"naturally-occurring." For example, when a cell divides, it
makes a copy of its DNA — and sometimes the copy is not
quite perfect. That small difference from the original DNA
sequence is a mutation.
2. External influences can create mutations
Mutations can also be caused by radiation. These agents cause the DNA to break
down. This is not necessarily unnatural. when the cell repairs the DNA, it might not
do a perfect e repair. So the cell would end up with DNA slightly different than the
original DNA and hence, a mutation
5. Types of Mutation
Mutations can occur in two
different types of cells:
1. Somatic (body) cells
2. Gamete (sex) cells
6. Mutation in Somatic Cell
Mutations that occur in
somatic (body) cells usually
result in killing that body
cell only.
An exception to this is if the
mutation occurs to the DNA
that controls regulation of
the cell cycle. This can result
in cancer.
Somatic mutations usually
do not affect the individual.
Somatic mutations can NOT
be passed on to the next
generation.
7. Mutation in Gamete Cells
Mutations that occur in gamete (sex) cells means that
every cell of the developing fetus/baby will have that
mutation.
Gamete mutations usually do affect the individual with
some genetic disorder.
Gamete mutations can be passed on to the next
generation
8. Two types of mutation in gamete cell
1. Gene Mutations
2. Chromosomal Mutations
9. Type of Single Gene Mutations -
Point
.
It’s a point mutation and type of single gene
mutation