Molecular studies of cells are leading to discover the more complex structure and function of tissues, and how this intervenes in the pathophysiology of diseases. During years scientists have made a laborious job to understand the origin of diseases that in our society are being more prevalent than some decades ago, such as cancer and congenital malformations
Molecular studies of cells are leading to discover the more complex structure and function of tissues, and how this intervenes in the pathophysiology of diseases. During years scientists have made a laborious job to understand the origin of diseases that in our society are being more prevalent than some decades ago, such as cancer and congenital malformations
This is the first presentation of the BITS training on 'Comparative genomics'.
It reviews the basic concepts of sequence homology on different levels.
Thanks to Klaas Vandepoele of the PSB department.
The Human Genome Project (HGP) was an international scientific research project with the goal of determining the base pairs that make up human DNA, and of identifying and mapping all of the genes of the human genome from both a physical and a functional standpoint.
This is the first presentation of the BITS training on 'Comparative genomics'.
It reviews the basic concepts of sequence homology on different levels.
Thanks to Klaas Vandepoele of the PSB department.
The Human Genome Project (HGP) was an international scientific research project with the goal of determining the base pairs that make up human DNA, and of identifying and mapping all of the genes of the human genome from both a physical and a functional standpoint.
Presentatie MO*lezing jacqueline mcglade over Een groene economie binnen de g...Mondiaal nieuws
Op woensdag 10 oktober 2012 vond in de Beursschouwburg in Brussel een boeiende MO*lezing plaats met als titel ‘Een groene economie binnen de grenzen van onze planeet’. Sprekers waren de internationaal gerenommeerde milieu-experts Jacqueline McGlade en Joachim Spangenberg. Dit is de presentatie van Jacqueline McGlade.
Chapter 3BiopsychologyFigure 3.1 Different brain imagi.docxwalterl4
Chapter 3
Biopsychology
Figure 3.1 Different brain imaging techniques provide scientists with insight into different aspects of how the human
brain functions. Left to right, PET scan (positron emission tomography), CT scan (computed tomography), and fMRI
(functional magnetic resonance imaging) are three types of scans. (credit “left”: modification of work by Health and
Human Services Department, National Institutes of Health; credit “center": modification of work by
"Aceofhearts1968"/Wikimedia Commons; credit “right”: modification of work by Kim J, Matthews NL, Park S.)
Chapter Outline
3.1 Human Genetics
3.2 Cells of the Nervous System
3.3 Parts of the Nervous System
3.4 The Brain and Spinal Cord
3.5 The Endocrine System
Introduction
Have you ever taken a device apart to find out how it works? Many of us have done so, whether to attempt
a repair or simply to satisfy our curiosity. A device’s internal workings are often distinct from its user
interface on the outside. For example, we don’t think about microchips and circuits when we turn up
the volume on a mobile phone; instead, we think about getting the volume just right. Similarly, the inner
workings of the human body are often distinct from the external expression of those workings. It is the
job of psychologists to find the connection between these—for example, to figure out how the firings of
millions of neurons become a thought.
This chapter strives to explain the biological mechanisms that underlie behavior. These physiological and
anatomical foundations are the basis for many areas of psychology. In this chapter, you will learn how
genetics influence both physiological and psychological traits. You will become familiar with the structure
and function of the nervous system. And, finally, you will learn how the nervous system interacts with the
endocrine system.
Chapter 3 | Biopsychology 73
3.1 Human Genetics
Learning Objectives
By the end of this section, you will be able to:
• Explain the basic principles of the theory of evolution by natural selection
• Describe the differences between genotype and phenotype
• Discuss how gene-environment interactions are critical for expression of physical and
psychological characteristics
Psychological researchers study genetics in order to better understand the biological basis that contributes
to certain behaviors. While all humans share certain biological mechanisms, we are each unique. And
while our bodies have many of the same parts—brains and hormones and cells with genetic codes—these
are expressed in a wide variety of behaviors, thoughts, and reactions.
Why do two people infected by the same disease have different outcomes: one surviving and one
succumbing to the ailment? How are genetic diseases passed through family lines? Are there genetic
components to psychological disorders, such as depression or schizophrenia? To what extent might there
be a psychological basis to health conditions such as childhood obesity?
To e.
Chapter 3BiopsychologyFigure 3.1 Different brain imagi.docxketurahhazelhurst
Chapter 3
Biopsychology
Figure 3.1 Different brain imaging techniques provide scientists with insight into different aspects of how the human
brain functions. Left to right, PET scan (positron emission tomography), CT scan (computed tomography), and fMRI
(functional magnetic resonance imaging) are three types of scans. (credit “left”: modification of work by Health and
Human Services Department, National Institutes of Health; credit “center": modification of work by
"Aceofhearts1968"/Wikimedia Commons; credit “right”: modification of work by Kim J, Matthews NL, Park S.)
Chapter Outline
3.1 Human Genetics
3.2 Cells of the Nervous System
3.3 Parts of the Nervous System
3.4 The Brain and Spinal Cord
3.5 The Endocrine System
Introduction
Have you ever taken a device apart to find out how it works? Many of us have done so, whether to attempt
a repair or simply to satisfy our curiosity. A device’s internal workings are often distinct from its user
interface on the outside. For example, we don’t think about microchips and circuits when we turn up
the volume on a mobile phone; instead, we think about getting the volume just right. Similarly, the inner
workings of the human body are often distinct from the external expression of those workings. It is the
job of psychologists to find the connection between these—for example, to figure out how the firings of
millions of neurons become a thought.
This chapter strives to explain the biological mechanisms that underlie behavior. These physiological and
anatomical foundations are the basis for many areas of psychology. In this chapter, you will learn how
genetics influence both physiological and psychological traits. You will become familiar with the structure
and function of the nervous system. And, finally, you will learn how the nervous system interacts with the
endocrine system.
Chapter 3 | Biopsychology 73
3.1 Human Genetics
Learning Objectives
By the end of this section, you will be able to:
• Explain the basic principles of the theory of evolution by natural selection
• Describe the differences between genotype and phenotype
• Discuss how gene-environment interactions are critical for expression of physical and
psychological characteristics
Psychological researchers study genetics in order to better understand the biological basis that contributes
to certain behaviors. While all humans share certain biological mechanisms, we are each unique. And
while our bodies have many of the same parts—brains and hormones and cells with genetic codes—these
are expressed in a wide variety of behaviors, thoughts, and reactions.
Why do two people infected by the same disease have different outcomes: one surviving and one
succumbing to the ailment? How are genetic diseases passed through family lines? Are there genetic
components to psychological disorders, such as depression or schizophrenia? To what extent might there
be a psychological basis to health conditions such as childhood obesity?
To e ...
Genes and Tissue Culture Technology Assignment (G6)Rohini Krishnan
The culture of cells in two dimensions does not reproduce the histological characteristics of a tissue for informative or useful study. Growing cells as three-dimensional (3D) models more analogous to their existence in vivo may be more clinically relevant.
State of ICS and IoT Cyber Threat Landscape Report 2024 previewPrayukth K V
The IoT and OT threat landscape report has been prepared by the Threat Research Team at Sectrio using data from Sectrio, cyber threat intelligence farming facilities spread across over 85 cities around the world. In addition, Sectrio also runs AI-based advanced threat and payload engagement facilities that serve as sinks to attract and engage sophisticated threat actors, and newer malware including new variants and latent threats that are at an earlier stage of development.
The latest edition of the OT/ICS and IoT security Threat Landscape Report 2024 also covers:
State of global ICS asset and network exposure
Sectoral targets and attacks as well as the cost of ransom
Global APT activity, AI usage, actor and tactic profiles, and implications
Rise in volumes of AI-powered cyberattacks
Major cyber events in 2024
Malware and malicious payload trends
Cyberattack types and targets
Vulnerability exploit attempts on CVEs
Attacks on counties – USA
Expansion of bot farms – how, where, and why
In-depth analysis of the cyber threat landscape across North America, South America, Europe, APAC, and the Middle East
Why are attacks on smart factories rising?
Cyber risk predictions
Axis of attacks – Europe
Systemic attacks in the Middle East
Download the full report from here:
https://sectrio.com/resources/ot-threat-landscape-reports/sectrio-releases-ot-ics-and-iot-security-threat-landscape-report-2024/
Epistemic Interaction - tuning interfaces to provide information for AI supportAlan Dix
Paper presented at SYNERGY workshop at AVI 2024, Genoa, Italy. 3rd June 2024
https://alandix.com/academic/papers/synergy2024-epistemic/
As machine learning integrates deeper into human-computer interactions, the concept of epistemic interaction emerges, aiming to refine these interactions to enhance system adaptability. This approach encourages minor, intentional adjustments in user behaviour to enrich the data available for system learning. This paper introduces epistemic interaction within the context of human-system communication, illustrating how deliberate interaction design can improve system understanding and adaptation. Through concrete examples, we demonstrate the potential of epistemic interaction to significantly advance human-computer interaction by leveraging intuitive human communication strategies to inform system design and functionality, offering a novel pathway for enriching user-system engagements.
The Art of the Pitch: WordPress Relationships and SalesLaura Byrne
Clients don’t know what they don’t know. What web solutions are right for them? How does WordPress come into the picture? How do you make sure you understand scope and timeline? What do you do if sometime changes?
All these questions and more will be explored as we talk about matching clients’ needs with what your agency offers without pulling teeth or pulling your hair out. Practical tips, and strategies for successful relationship building that leads to closing the deal.
Transcript: Selling digital books in 2024: Insights from industry leaders - T...BookNet Canada
The publishing industry has been selling digital audiobooks and ebooks for over a decade and has found its groove. What’s changed? What has stayed the same? Where do we go from here? Join a group of leading sales peers from across the industry for a conversation about the lessons learned since the popularization of digital books, best practices, digital book supply chain management, and more.
Link to video recording: https://bnctechforum.ca/sessions/selling-digital-books-in-2024-insights-from-industry-leaders/
Presented by BookNet Canada on May 28, 2024, with support from the Department of Canadian Heritage.
GDG Cloud Southlake #33: Boule & Rebala: Effective AppSec in SDLC using Deplo...James Anderson
Effective Application Security in Software Delivery lifecycle using Deployment Firewall and DBOM
The modern software delivery process (or the CI/CD process) includes many tools, distributed teams, open-source code, and cloud platforms. Constant focus on speed to release software to market, along with the traditional slow and manual security checks has caused gaps in continuous security as an important piece in the software supply chain. Today organizations feel more susceptible to external and internal cyber threats due to the vast attack surface in their applications supply chain and the lack of end-to-end governance and risk management.
The software team must secure its software delivery process to avoid vulnerability and security breaches. This needs to be achieved with existing tool chains and without extensive rework of the delivery processes. This talk will present strategies and techniques for providing visibility into the true risk of the existing vulnerabilities, preventing the introduction of security issues in the software, resolving vulnerabilities in production environments quickly, and capturing the deployment bill of materials (DBOM).
Speakers:
Bob Boule
Robert Boule is a technology enthusiast with PASSION for technology and making things work along with a knack for helping others understand how things work. He comes with around 20 years of solution engineering experience in application security, software continuous delivery, and SaaS platforms. He is known for his dynamic presentations in CI/CD and application security integrated in software delivery lifecycle.
Gopinath Rebala
Gopinath Rebala is the CTO of OpsMx, where he has overall responsibility for the machine learning and data processing architectures for Secure Software Delivery. Gopi also has a strong connection with our customers, leading design and architecture for strategic implementations. Gopi is a frequent speaker and well-known leader in continuous delivery and integrating security into software delivery.
Observability Concepts EVERY Developer Should Know -- DeveloperWeek Europe.pdfPaige Cruz
Monitoring and observability aren’t traditionally found in software curriculums and many of us cobble this knowledge together from whatever vendor or ecosystem we were first introduced to and whatever is a part of your current company’s observability stack.
While the dev and ops silo continues to crumble….many organizations still relegate monitoring & observability as the purview of ops, infra and SRE teams. This is a mistake - achieving a highly observable system requires collaboration up and down the stack.
I, a former op, would like to extend an invitation to all application developers to join the observability party will share these foundational concepts to build on:
GraphSummit Singapore | The Future of Agility: Supercharging Digital Transfor...Neo4j
Leonard Jayamohan, Partner & Generative AI Lead, Deloitte
This keynote will reveal how Deloitte leverages Neo4j’s graph power for groundbreaking digital twin solutions, achieving a staggering 100x performance boost. Discover the essential role knowledge graphs play in successful generative AI implementations. Plus, get an exclusive look at an innovative Neo4j + Generative AI solution Deloitte is developing in-house.
Removing Uninteresting Bytes in Software FuzzingAftab Hussain
Imagine a world where software fuzzing, the process of mutating bytes in test seeds to uncover hidden and erroneous program behaviors, becomes faster and more effective. A lot depends on the initial seeds, which can significantly dictate the trajectory of a fuzzing campaign, particularly in terms of how long it takes to uncover interesting behaviour in your code. We introduce DIAR, a technique designed to speedup fuzzing campaigns by pinpointing and eliminating those uninteresting bytes in the seeds. Picture this: instead of wasting valuable resources on meaningless mutations in large, bloated seeds, DIAR removes the unnecessary bytes, streamlining the entire process.
In this work, we equipped AFL, a popular fuzzer, with DIAR and examined two critical Linux libraries -- Libxml's xmllint, a tool for parsing xml documents, and Binutil's readelf, an essential debugging and security analysis command-line tool used to display detailed information about ELF (Executable and Linkable Format). Our preliminary results show that AFL+DIAR does not only discover new paths more quickly but also achieves higher coverage overall. This work thus showcases how starting with lean and optimized seeds can lead to faster, more comprehensive fuzzing campaigns -- and DIAR helps you find such seeds.
- These are slides of the talk given at IEEE International Conference on Software Testing Verification and Validation Workshop, ICSTW 2022.
Essentials of Automations: The Art of Triggers and Actions in FMESafe Software
In this second installment of our Essentials of Automations webinar series, we’ll explore the landscape of triggers and actions, guiding you through the nuances of authoring and adapting workspaces for seamless automations. Gain an understanding of the full spectrum of triggers and actions available in FME, empowering you to enhance your workspaces for efficient automation.
We’ll kick things off by showcasing the most commonly used event-based triggers, introducing you to various automation workflows like manual triggers, schedules, directory watchers, and more. Plus, see how these elements play out in real scenarios.
Whether you’re tweaking your current setup or building from the ground up, this session will arm you with the tools and insights needed to transform your FME usage into a powerhouse of productivity. Join us to discover effective strategies that simplify complex processes, enhancing your productivity and transforming your data management practices with FME. Let’s turn complexity into clarity and make your workspaces work wonders!
Dr. Sean Tan, Head of Data Science, Changi Airport Group
Discover how Changi Airport Group (CAG) leverages graph technologies and generative AI to revolutionize their search capabilities. This session delves into the unique search needs of CAG’s diverse passengers and customers, showcasing how graph data structures enhance the accuracy and relevance of AI-generated search results, mitigating the risk of “hallucinations” and improving the overall customer journey.
Elevating Tactical DDD Patterns Through Object CalisthenicsDorra BARTAGUIZ
After immersing yourself in the blue book and its red counterpart, attending DDD-focused conferences, and applying tactical patterns, you're left with a crucial question: How do I ensure my design is effective? Tactical patterns within Domain-Driven Design (DDD) serve as guiding principles for creating clear and manageable domain models. However, achieving success with these patterns requires additional guidance. Interestingly, we've observed that a set of constraints initially designed for training purposes remarkably aligns with effective pattern implementation, offering a more ‘mechanical’ approach. Let's explore together how Object Calisthenics can elevate the design of your tactical DDD patterns, offering concrete help for those venturing into DDD for the first time!
GraphSummit Singapore | The Art of the Possible with Graph - Q2 2024Neo4j
Neha Bajwa, Vice President of Product Marketing, Neo4j
Join us as we explore breakthrough innovations enabled by interconnected data and AI. Discover firsthand how organizations use relationships in data to uncover contextual insights and solve our most pressing challenges – from optimizing supply chains, detecting fraud, and improving customer experiences to accelerating drug discoveries.
Why You Should Replace Windows 11 with Nitrux Linux 3.5.0 for enhanced perfor...SOFTTECHHUB
The choice of an operating system plays a pivotal role in shaping our computing experience. For decades, Microsoft's Windows has dominated the market, offering a familiar and widely adopted platform for personal and professional use. However, as technological advancements continue to push the boundaries of innovation, alternative operating systems have emerged, challenging the status quo and offering users a fresh perspective on computing.
One such alternative that has garnered significant attention and acclaim is Nitrux Linux 3.5.0, a sleek, powerful, and user-friendly Linux distribution that promises to redefine the way we interact with our devices. With its focus on performance, security, and customization, Nitrux Linux presents a compelling case for those seeking to break free from the constraints of proprietary software and embrace the freedom and flexibility of open-source computing.
1. Molecular Biology – NEWS
Genome’s 3D Structure shapes how genes are expressed.
Down syndrome gene suppresed by scientists.
Maria Isabel Palacio Mejía
Medical Student in 3rd Semester
ECS – UPB. 2013 II
4. Molecular Biology – NEWS
Cooper GM, Hausman RF. The Cell: A Molecular Approach. 3. ed. Washington,
DC, USA: ASM Press; 2007.
The histones package DNA in an ordely manner in the
nucleus of the cell, resulting chomosomes.
In molecular terms, a gene can define like a segment of
DNA, that is expressed to yeild in a final product.
Genes are composed of coding segmente (exons), wich are
separated by non-coding segments (intrones).
5. Molecular Biology – NEWS
Genome’s 3D Structure Shapes How Genes Are Expressed [Internet]. Asian Sci. Mag. Sci.
Technol. Med. News Updat. Asia. [cited 2013 Jul 28]. Available from:
http://www.asianscientist.com/in-the-lab/genomes-3d-structure-shapes-genes-expressed-2013/
We understan relatively little about the
3D structure of the genoma.
As international team of scientists has
analysed the genome’s 3D structure of
high resolution
6. Molecular Biology – NEWS
Genome’s 3D Structure Shapes How Genes Are Expressed [Internet]. Asian Sci. Mag. Sci.
Technol. Med. News Updat. Asia. [cited 2013 Jul 28]. Available from:
http://www.asianscientist.com/in-the-lab/genomes-3d-structure-shapes-genes-expressed-2013/
In this study, researchers used the vast amount
of data from the ENCODE project to infer how the
genome is folded up.
The same gene can generete different proteins.
From this analysis, found that even within a gene,
there are selected exons wich are more easily
exposed compared to others.
7. Molecular Biology – NEWS
Genome’s 3D Structure Shapes How Genes Are Expressed [Internet]. Asian Sci. Mag. Sci.
Technol. Med. News Updat. Asia. [cited 2013 Jul 28]. Available from:
http://www.asianscientist.com/in-the-lab/genomes-3d-structure-shapes-genes-expressed-2013/
3D structure of the genoma can influence the wich
exons of the genes are included in the final protein
product
8. Molecular Biology – NEWS
Genome’s 3D Structure Shapes How Genes Are Expressed [Internet]. Asian Sci. Mag. Sci.
Technol. Med. News Updat. Asia. [cited 2013 Jul 28]. Available from:
http://www.asianscientist.com/in-the-lab/genomes-3d-structure-shapes-genes-expressed-2013/
Different versions of the protein maybe
produced by the same gene under
different conditions, depending on the
structure of the genoma at the time.
9. Molecular Biology – NEWS
PERSONAL OPINION
This news show us the knowledge
is in continuosly evolution, now we
know that our genetic code have a
organization form that expand the
posibility of combinations and of
course the results, this represent
new oportunities, the door of the
future.
This news show us the knowledge
is in continuosly evolution, now we
know that our genetic code have a
organization form that expand the
posibility of combinations and of
course the results, this represent
new oportunities, the door of the
future.
10. Molecular Biology – NEWS
Down syndrome cells suppressed by scientists - Technology & Science - CBC News [Internet].
Cbcnews Technol. Sci. [cited 2013 Jul 28]. Available from:
http://www.cbc.ca/news/technology/story/2013/07/18/sci-down-syndrome-gene-suppressed.html
The University of Massachusetts Medical School say they
have found a way to supress the effect of the extra
chromosome that causes Down Syndrome.
11. Molecular Biology – NEWS
Down syndrome cells suppressed by scientists - Technology & Science - CBC News [Internet].
Cbcnews Technol. Sci. [cited 2013 Jul 28]. Available from:
http://www.cbc.ca/news/technology/story/2013/07/18/sci-down-syndrome-gene-suppressed.html
Brings into the realm of consideration
research an the concept of “chromosome
therapy” in the future” said Jeanne
Lawrence.
12. Molecular Biology – NEWS
Down syndrome cells suppressed by scientists - Technology & Science - CBC News [Internet].
Cbcnews Technol. Sci. [cited 2013 Jul 28]. Available from:
http://www.cbc.ca/news/technology/story/2013/07/18/sci-down-syndrome-gene-suppressed.html
Using lab-grown stem cells with
Down syndrome, Lawrence’s team
spliced in a RNA gene called Xirst,
wich normally functions to muzzle
one of the two X chromosomes
found in famale embryos.
13. Molecular Biology – NEWS
Down syndrome cells suppressed by scientists - Technology & Science - CBC News [Internet].
Cbcnews Technol. Sci. [cited 2013 Jul 28]. Available from:
http://www.cbc.ca/news/technology/story/2013/07/18/sci-down-syndrome-gene-suppressed.html
Xist functioned to modify the structure of the estra
chromosome to desactivate most of its genes and
prevent the production of proteins and other
elements.
14. Molecular Biology – NEWS
PERSONAL OPINION
This news shows us the
importance of research, wich blurs
the limits and allows us to advance
more and more; creating new
possibilities and become real
things that at some point were
dreams as gene therapy. It is the
biginning of new forms of
therapeutic
This news shows us the
importance of research, wich blurs
the limits and allows us to advance
more and more; creating new
possibilities and become real
things that at some point were
dreams as gene therapy. It is the
biginning of new forms of
therapeutic
15. Molecular Biology – NEWS
MEDICAL UTILITY
This news shows
us that the
future is as big
as our
imagination
allows. This
results are
importante
because
represent the
biginning of a
new era.
16. Molecular Biology – NEWS
MEDICAL UTILITY
The new research opens a door for
us like Doctors, for new knowlege to
understantand the human body and
with that the tools for new
intervention, in the search of better
quality of life.
17. Molecular Biology – NEWS
MEDICAL UTILITY
Now we can talk about a new form of
gene expression, and the possibility of
a new therapeutic form that have a big
impact in the society
