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International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056
Volume: 09 Issue: 07 | July 2022 www.irjet.net p-ISSN: 2395-0072
© 2022, IRJET | Impact Factor value: 7.529 | ISO 9001:2008 Certified Journal | Page 903
PREDICTION OF COVID-19 USING MACHINE LEARNING APPROACHES
UTKARSH ANIL BAVISKAR
VISHWAKARMA INSTITUTE OF INORMATION TECHNOLOGY, PUNE
---------------------------------------------------------------------***---------------------------------------------------------------------
Abstract - The outbreak of the COVID19 virus, called
SARSCoV2, has created a pandemic situation worldwide. The
cases of COVID19 are increasing rapidly every day. Machine
learning (ML) and cloud computing can be implemented very
effectively to track diseases, predict epidemic growth, and
develop strategies and guidelines to control their spread. This
study uses improved mathematical models to analyze and
predict the growth of virus. We appliedan improvedML-based
model to predict potential COVID-19 threats in countries
around the world. Prediction of COVID-19 can be done by
iteratively weighting to approximate the generalized inverse
Weibull distribution. It has been deployed on cloud platforms
to more accurately and realistically predict the dynamics of
epidemic growth. It is a more accurate data-driven approach
as it can be very useful for government and citizens of the
nation. Hence, we propose a research and setup grounds for
further research.
Key Words: Machine learning, COVID-19, AI, SVM,
Random Forest, Decision Tree, Linear Regression
1. INTRODUCTION
The novel coronavirus infection (COVID-19) was first
reported in Wuhan, Hubei Province, China on December 31,
2019. It began to spread rapidly around the world. The
cumulative incidence of this virus (SARSCoV2) is increasing
rapidly and has affected 196 countries and territories, of
which the United States, Spain, Italy, United Kingdom and
France have been most affected. WHO has declared a global
pandemic for the coronavirus infection (COVID-19), and the
virus continues to spread. As of May 4, 2020, there were
3,581,884 confirmed cases and 248,558 deaths. The main
difference between the CoV2 pandemic and related viruses
such as severe acute respiratory syndrome (SARS) and
Middle East respiratory syndrome (MERS) is that CoV2
spreads rapidly through human contact and nearly 20% of
infected subjects remain asymptomatic carrier. In addition,
various studies have reported that CoV2-induced disease is
more at risk for people with weakenedimmunesystems. The
elderly and those with life-threatening diseases such as
cancer, diabetes, neurological diseases, coronary heart
disease and HIV/AIDS are more vulnerable to the serious
consequences of COVID-19. In the absence of drugs, theonly
solution is to slow the spread of the virus by applying"social
distancing" to break the transmissionchain. Thisbehaviorof
CoV2 requires the development of a robust mathematical
framework to track the spread and the automation of
tracking tools to make dynamic decisions online. Innovative
solutions are needed to develop, manage, and analyze big
data for growing target networks, patient information, and
big data for movement within communities, as well as
integration with clinical trial and pharmaceutical data,
genomic data and public health data. Multiple data sources,
including text messages, online communications, social
media, and web articles, can be very useful in analyzing the
increase in infections caused by community behavior. By
wrapping this data with machine learning(ML)andartificial
intelligence (AI), researchers can predict when and where a
disease may spread and notify the area to agree on the
necessary action.Byautomaticallytrackingthetravel history
of infected subjects, you can study epidemiologic
correlations with disease spread in specific communities.
2. MOTIVATION AND OUR CONTRIBUTIONS
ML can be used to process large amounts of data and
intelligently predict thespreadof a disease.Cloudcomputing
can be used to rapidly improve the forecasting process with
high-speed computing. New energy-efficient peripheral
systems can be used to collect data to reduce power
consumption. In this article, we present a predictive model
deployed using the FogBus framework to accurately predict
the number of COVID-19 cases, an increase and decrease in
the number of cases in the near future, and the date the
pandemic can be expected to end in other countries.Wealso
provide a detailed comparison with the baseline model and
show how devastating the impact can be if a poorly matched
model is used. We empower governments and citizens to be
proactive by presenting a prediction framework based on
machine learning models that can be used to make real-time
predictions from remote cloud nodes. In conclusion, we
summarize this work and present various lines of research.
3. SOFTWARE PLATFORMS
• Python
Python is an open source programming language. Currently
in high demand in the IT industry. It is mainly used for
machine learning for website development, data processing,
software, etc. Python is almost similar to C, except that the
coding syntax is different. You can perform many types of
tasks and use them to build machine learning, data analysis,
and complex statistical calculations.
• Machine Learning Model
Many recent studies have shown that the spread of COVID-
19 follows an exponential distribution. Empirical estimates
International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056
Volume: 09 Issue: 07 | July 2022 www.irjet.net p-ISSN: 2395-0072
© 2022, IRJET | Impact Factor value: 7.529 | ISO 9001:2008 Certified Journal | Page 904
of the SARSCoV2 pandemic and previous data sets have
shown that many sources have a large number of outliers in
the data corresponding to new cases over time, which may
or may not follow a standard distribution such as a Gaussian
or exponential distribution. In a recent study by the
Singapore UniversityofTechnologyandDesign(SUTD)Data-
Driven Innovation Lab, a Susceptible Infected Recovered
model was used to construct a regression curve and
distributed a Gaussian distribution to estimate the number
of cases over time. However, in the previously described
study, an older version of the virus called SARSCoV2
followed the generalized inverse Weibull distribution(GIW)
better than Gaussian.
4. PREDICTION MODEL AND PERFORMANCE
COMPARISONS
The machine learning (ML) and data science communities
are working hard to improve the predictions of
epidemiologic models and analyze information sent via
Twitter to develop governance strategies and evaluate the
impact of policies to contain the spread. Various data sets
have been published publicly on this topic. However, as
COVID-19 spreads globally, more data needs to be collected,
processed and analyzed. The novel coronavirus is having a
serious socio-economic impact worldwide. Countries with
large populations should be more vigilant as the virus is
easily transmitted through droplets or runny nose, mainly
when an infected person coughs or sneezes. To get detailed
information about the impact of COVID-19 on the world's
population, and to predict the number of COVID-19 cases in
different countries and when the pandemic is expected to
end, we propose a machine learning model that can be run
continuously in cloud data centers.(CDC).Accuratelypredict
outbreaks and proactively develop strategic responses.
5. DATASETS
The dataset used in this case study is our world in Data2 by
Hannah Ritchie. The dataset is updated daily basedonstatus
reports from the World Health Organization (WHO). More
information about the dataset can be found on our website:
https://ourworldindata.org/coronavirus-source-data.
6. ALGORITHMS
1. SVM
SVM was chosen because it transforms an inseparable
problem into a separable problem by using a kernel trick to
transform a low-dimensional input space into a high-
dimensional space. We split the dataset into a train set and a
test set in a ratio of 7:3, and using a linear kernel, the SVM
classifier uses a hyperplane to linearly divide the data. Each
data class is separated by parallel hyperplanes to keep
distances as large as possible.
2. Random Forest,
Random Forest is an ensemble technique that can perform
both regression and classification tasks using multiple
decision trees and techniques commonly known as
bootstrap and aggregation known as packaging. The main
idea behind this is to combine multiple decision trees to
determine the final result instead of relying on separate
decision trees.
The Random Forest has several decision trees as the basic
learning model. We perform row sampling randomization
and feature sampling from the dataset forming a sample
dataset for each model. This section is called Bootstrap.
3. Decision Tree
Decision trees are very successful classifiersappliedinmany
domains. Decision trees are constructed using a recursive
partitioning process in which data points are partitioned at
each node using selected partitioning criteria.The pathfrom
the root node to the sheet is the rule used for prediction. An
ensemble of classifiers consists of a set of classifiers [18].
The final decision is the combination of all member
classifiers. Ensembles generally perform better than
individual members when their individual members are
precise and varied. Decision tree ensemblesarefairlyrobust
and perform well. The experiment usesseveral ensembles of
decision trees. Decision tree ensembles designed for
unbalanced datasets are also used because the data are
unbalanced.
4. Linear regression
Since we are dealing with COVID-19 data, observations
suggest that COVID-19 data do not follow a linear property.
Rather, it follows a linear property for a short time and then
changes direction. In this case, it is not suitable for linear
regression, and if you still use it for linear regression, the
prediction is far from real.
6. MAE/MSE SCORE
Name of
Algorithm
MAE MSE
SVM 113952693.00
743757
1.4189100362824158e+
16
Linear
Regression
29503683.939
641554
876863594001211.8
Decision Tree 25613676.380
95238
869104703463814.2
Random
Forest
Classifier
25613676.380
95238
869104703463814.2
International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056
Volume: 09 Issue: 07 | July 2022 www.irjet.net p-ISSN: 2395-0072
© 2022, IRJET | Impact Factor value: 7.529 | ISO 9001:2008 Certified Journal | Page 905
7. RESULTS
Fig:7.1: Number of Cases
Fig.7.2: Number of Cases pie-chart
Fig.7.3: SVM Predictions
Fig.7.4: Linear Regression Prediction
fig.7.5: Decision Tree Prediction
fig.7.6: Random Forest Prediction
International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056
Volume: 09 Issue: 07 | July 2022 www.irjet.net p-ISSN: 2395-0072
© 2022, IRJET | Impact Factor value: 7.529 | ISO 9001:2008 Certified Journal | Page 906
fig.7.7: Final Prediction
8. OUTPUT SCREENS
fig.8.1: Dashboard
Fig.8.2: Dashboard with FAQ questions
Fig.8.3: Prediction using Weibull Distribution
Fig.8.4. Select country for prediction with Weilbull
Distribution
Fig.8.5. Final Prediction using Weilbull Distribution
fig.8.6: Prediction using ML algorithms
International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056
Volume: 09 Issue: 07 | July 2022 www.irjet.net p-ISSN: 2395-0072
© 2022, IRJET | Impact Factor value: 7.529 | ISO 9001:2008 Certified Journal | Page 907
9. SUMMARY AND CONCLUSIONS
In this study, we discussed how machine learning, andcloud
computing can help in predicting of the growth of pandemic.
Additionally, case studies have been published
demonstrating the severity of the spread of CoV-2 in
countries around the world. Using the proposed robust
Weibull model based on iterative weighting, we show that
our model can make statistically better predictions than the
baseline. The baseline Gaussian model shows an overly
optimistic picture of the COVID-19 scenario. SVM algorithm
having MAE as 113952693.00743757 and MSE as
1.4189100362824158e+16.
10. REFERENCES
[1] COVID Live - Coronavirus Statistics - Worldometer.
(2021).https://www.worldometers.info/coronavirus/R.
Nicole, “Title of paper with only firstwordcapitalized,”J.
Name Stand. Abbrev., in press.
[2] Wang, C., Horby, P. W., Hayden, F. G., & Gao, G. F. (2020).
A novel coronavirus outbreak of global health concern.
The Lancet, 395(10223), 470–473.
https://doi.org/10.1016/s0140-6736(20)30185-9.
[3] Guangdi Li and Erik De Clercq. Therapeutic options for
the 2019 novel coronavirus (2019-ncov), 2020.
[4] Smriti Mallapaty. What thecruise-shipoutbreaksreveal
about covid-19. Nature, 580(7801):18–18, 2020.
[5] Kai Liu, Ying Chen, Ruzheng Lin, and Kunyuan Han.
Clinical features of covid-19 in elderly patients: A
comparison with young and middle-aged patients.
Journal of Infection, 2020.
[6] Shi Zhao, Qianyin Lin, Jinjun Ran, Salihu S Musa,
Guangpu Yang, Weiming Wang, Yijun Lou,DaozhouGao,
Lin Yang, Daihai He, et al. Preliminary estimation of the
basic reproduction number of novel coronavirus(2019-
ncov) in china, from 2019 to 2020: A data-driven
analysis in the early phase of theoutbreak.International
Journal of Infectious Diseases, 92:214–217, 2020.
[7] Shreshth Tuli, Shikhar Tuli, Gurleen Wander, Praneet
Wander, Sukhpal Singh Gill, Schahram Dustdar, Rizos
Sakellariou, and Omer Rana. Next generation
technologies for smart healthcare: Challenges, vision,
model, trends and future directions. Internet
Technology Letters, page e145.
[8] Chaolin Huang, Yeming Wang, Xingwang Li, Lili Ren,
Jianping Zhao, Yi Hu, Li Zhang, Guohui Fan, Jiuyang Xu,
Xiaoying Gu, et al. Clinical features of patients infected
with 2019 novel coronavirus in Wuhan, China. The
Lancet, 395(10223):497–506, 2020.

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PREDICTION OF COVID-19 USING MACHINE LEARNING APPROACHES

  • 1. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 09 Issue: 07 | July 2022 www.irjet.net p-ISSN: 2395-0072 © 2022, IRJET | Impact Factor value: 7.529 | ISO 9001:2008 Certified Journal | Page 903 PREDICTION OF COVID-19 USING MACHINE LEARNING APPROACHES UTKARSH ANIL BAVISKAR VISHWAKARMA INSTITUTE OF INORMATION TECHNOLOGY, PUNE ---------------------------------------------------------------------***--------------------------------------------------------------------- Abstract - The outbreak of the COVID19 virus, called SARSCoV2, has created a pandemic situation worldwide. The cases of COVID19 are increasing rapidly every day. Machine learning (ML) and cloud computing can be implemented very effectively to track diseases, predict epidemic growth, and develop strategies and guidelines to control their spread. This study uses improved mathematical models to analyze and predict the growth of virus. We appliedan improvedML-based model to predict potential COVID-19 threats in countries around the world. Prediction of COVID-19 can be done by iteratively weighting to approximate the generalized inverse Weibull distribution. It has been deployed on cloud platforms to more accurately and realistically predict the dynamics of epidemic growth. It is a more accurate data-driven approach as it can be very useful for government and citizens of the nation. Hence, we propose a research and setup grounds for further research. Key Words: Machine learning, COVID-19, AI, SVM, Random Forest, Decision Tree, Linear Regression 1. INTRODUCTION The novel coronavirus infection (COVID-19) was first reported in Wuhan, Hubei Province, China on December 31, 2019. It began to spread rapidly around the world. The cumulative incidence of this virus (SARSCoV2) is increasing rapidly and has affected 196 countries and territories, of which the United States, Spain, Italy, United Kingdom and France have been most affected. WHO has declared a global pandemic for the coronavirus infection (COVID-19), and the virus continues to spread. As of May 4, 2020, there were 3,581,884 confirmed cases and 248,558 deaths. The main difference between the CoV2 pandemic and related viruses such as severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS) is that CoV2 spreads rapidly through human contact and nearly 20% of infected subjects remain asymptomatic carrier. In addition, various studies have reported that CoV2-induced disease is more at risk for people with weakenedimmunesystems. The elderly and those with life-threatening diseases such as cancer, diabetes, neurological diseases, coronary heart disease and HIV/AIDS are more vulnerable to the serious consequences of COVID-19. In the absence of drugs, theonly solution is to slow the spread of the virus by applying"social distancing" to break the transmissionchain. Thisbehaviorof CoV2 requires the development of a robust mathematical framework to track the spread and the automation of tracking tools to make dynamic decisions online. Innovative solutions are needed to develop, manage, and analyze big data for growing target networks, patient information, and big data for movement within communities, as well as integration with clinical trial and pharmaceutical data, genomic data and public health data. Multiple data sources, including text messages, online communications, social media, and web articles, can be very useful in analyzing the increase in infections caused by community behavior. By wrapping this data with machine learning(ML)andartificial intelligence (AI), researchers can predict when and where a disease may spread and notify the area to agree on the necessary action.Byautomaticallytrackingthetravel history of infected subjects, you can study epidemiologic correlations with disease spread in specific communities. 2. MOTIVATION AND OUR CONTRIBUTIONS ML can be used to process large amounts of data and intelligently predict thespreadof a disease.Cloudcomputing can be used to rapidly improve the forecasting process with high-speed computing. New energy-efficient peripheral systems can be used to collect data to reduce power consumption. In this article, we present a predictive model deployed using the FogBus framework to accurately predict the number of COVID-19 cases, an increase and decrease in the number of cases in the near future, and the date the pandemic can be expected to end in other countries.Wealso provide a detailed comparison with the baseline model and show how devastating the impact can be if a poorly matched model is used. We empower governments and citizens to be proactive by presenting a prediction framework based on machine learning models that can be used to make real-time predictions from remote cloud nodes. In conclusion, we summarize this work and present various lines of research. 3. SOFTWARE PLATFORMS • Python Python is an open source programming language. Currently in high demand in the IT industry. It is mainly used for machine learning for website development, data processing, software, etc. Python is almost similar to C, except that the coding syntax is different. You can perform many types of tasks and use them to build machine learning, data analysis, and complex statistical calculations. • Machine Learning Model Many recent studies have shown that the spread of COVID- 19 follows an exponential distribution. Empirical estimates
  • 2. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 09 Issue: 07 | July 2022 www.irjet.net p-ISSN: 2395-0072 © 2022, IRJET | Impact Factor value: 7.529 | ISO 9001:2008 Certified Journal | Page 904 of the SARSCoV2 pandemic and previous data sets have shown that many sources have a large number of outliers in the data corresponding to new cases over time, which may or may not follow a standard distribution such as a Gaussian or exponential distribution. In a recent study by the Singapore UniversityofTechnologyandDesign(SUTD)Data- Driven Innovation Lab, a Susceptible Infected Recovered model was used to construct a regression curve and distributed a Gaussian distribution to estimate the number of cases over time. However, in the previously described study, an older version of the virus called SARSCoV2 followed the generalized inverse Weibull distribution(GIW) better than Gaussian. 4. PREDICTION MODEL AND PERFORMANCE COMPARISONS The machine learning (ML) and data science communities are working hard to improve the predictions of epidemiologic models and analyze information sent via Twitter to develop governance strategies and evaluate the impact of policies to contain the spread. Various data sets have been published publicly on this topic. However, as COVID-19 spreads globally, more data needs to be collected, processed and analyzed. The novel coronavirus is having a serious socio-economic impact worldwide. Countries with large populations should be more vigilant as the virus is easily transmitted through droplets or runny nose, mainly when an infected person coughs or sneezes. To get detailed information about the impact of COVID-19 on the world's population, and to predict the number of COVID-19 cases in different countries and when the pandemic is expected to end, we propose a machine learning model that can be run continuously in cloud data centers.(CDC).Accuratelypredict outbreaks and proactively develop strategic responses. 5. DATASETS The dataset used in this case study is our world in Data2 by Hannah Ritchie. The dataset is updated daily basedonstatus reports from the World Health Organization (WHO). More information about the dataset can be found on our website: https://ourworldindata.org/coronavirus-source-data. 6. ALGORITHMS 1. SVM SVM was chosen because it transforms an inseparable problem into a separable problem by using a kernel trick to transform a low-dimensional input space into a high- dimensional space. We split the dataset into a train set and a test set in a ratio of 7:3, and using a linear kernel, the SVM classifier uses a hyperplane to linearly divide the data. Each data class is separated by parallel hyperplanes to keep distances as large as possible. 2. Random Forest, Random Forest is an ensemble technique that can perform both regression and classification tasks using multiple decision trees and techniques commonly known as bootstrap and aggregation known as packaging. The main idea behind this is to combine multiple decision trees to determine the final result instead of relying on separate decision trees. The Random Forest has several decision trees as the basic learning model. We perform row sampling randomization and feature sampling from the dataset forming a sample dataset for each model. This section is called Bootstrap. 3. Decision Tree Decision trees are very successful classifiersappliedinmany domains. Decision trees are constructed using a recursive partitioning process in which data points are partitioned at each node using selected partitioning criteria.The pathfrom the root node to the sheet is the rule used for prediction. An ensemble of classifiers consists of a set of classifiers [18]. The final decision is the combination of all member classifiers. Ensembles generally perform better than individual members when their individual members are precise and varied. Decision tree ensemblesarefairlyrobust and perform well. The experiment usesseveral ensembles of decision trees. Decision tree ensembles designed for unbalanced datasets are also used because the data are unbalanced. 4. Linear regression Since we are dealing with COVID-19 data, observations suggest that COVID-19 data do not follow a linear property. Rather, it follows a linear property for a short time and then changes direction. In this case, it is not suitable for linear regression, and if you still use it for linear regression, the prediction is far from real. 6. MAE/MSE SCORE Name of Algorithm MAE MSE SVM 113952693.00 743757 1.4189100362824158e+ 16 Linear Regression 29503683.939 641554 876863594001211.8 Decision Tree 25613676.380 95238 869104703463814.2 Random Forest Classifier 25613676.380 95238 869104703463814.2
  • 3. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 09 Issue: 07 | July 2022 www.irjet.net p-ISSN: 2395-0072 © 2022, IRJET | Impact Factor value: 7.529 | ISO 9001:2008 Certified Journal | Page 905 7. RESULTS Fig:7.1: Number of Cases Fig.7.2: Number of Cases pie-chart Fig.7.3: SVM Predictions Fig.7.4: Linear Regression Prediction fig.7.5: Decision Tree Prediction fig.7.6: Random Forest Prediction
  • 4. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 09 Issue: 07 | July 2022 www.irjet.net p-ISSN: 2395-0072 © 2022, IRJET | Impact Factor value: 7.529 | ISO 9001:2008 Certified Journal | Page 906 fig.7.7: Final Prediction 8. OUTPUT SCREENS fig.8.1: Dashboard Fig.8.2: Dashboard with FAQ questions Fig.8.3: Prediction using Weibull Distribution Fig.8.4. Select country for prediction with Weilbull Distribution Fig.8.5. Final Prediction using Weilbull Distribution fig.8.6: Prediction using ML algorithms
  • 5. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 09 Issue: 07 | July 2022 www.irjet.net p-ISSN: 2395-0072 © 2022, IRJET | Impact Factor value: 7.529 | ISO 9001:2008 Certified Journal | Page 907 9. SUMMARY AND CONCLUSIONS In this study, we discussed how machine learning, andcloud computing can help in predicting of the growth of pandemic. Additionally, case studies have been published demonstrating the severity of the spread of CoV-2 in countries around the world. Using the proposed robust Weibull model based on iterative weighting, we show that our model can make statistically better predictions than the baseline. The baseline Gaussian model shows an overly optimistic picture of the COVID-19 scenario. SVM algorithm having MAE as 113952693.00743757 and MSE as 1.4189100362824158e+16. 10. REFERENCES [1] COVID Live - Coronavirus Statistics - Worldometer. (2021).https://www.worldometers.info/coronavirus/R. Nicole, “Title of paper with only firstwordcapitalized,”J. Name Stand. Abbrev., in press. [2] Wang, C., Horby, P. W., Hayden, F. G., & Gao, G. F. (2020). A novel coronavirus outbreak of global health concern. The Lancet, 395(10223), 470–473. https://doi.org/10.1016/s0140-6736(20)30185-9. [3] Guangdi Li and Erik De Clercq. Therapeutic options for the 2019 novel coronavirus (2019-ncov), 2020. [4] Smriti Mallapaty. What thecruise-shipoutbreaksreveal about covid-19. Nature, 580(7801):18–18, 2020. [5] Kai Liu, Ying Chen, Ruzheng Lin, and Kunyuan Han. Clinical features of covid-19 in elderly patients: A comparison with young and middle-aged patients. Journal of Infection, 2020. [6] Shi Zhao, Qianyin Lin, Jinjun Ran, Salihu S Musa, Guangpu Yang, Weiming Wang, Yijun Lou,DaozhouGao, Lin Yang, Daihai He, et al. Preliminary estimation of the basic reproduction number of novel coronavirus(2019- ncov) in china, from 2019 to 2020: A data-driven analysis in the early phase of theoutbreak.International Journal of Infectious Diseases, 92:214–217, 2020. [7] Shreshth Tuli, Shikhar Tuli, Gurleen Wander, Praneet Wander, Sukhpal Singh Gill, Schahram Dustdar, Rizos Sakellariou, and Omer Rana. Next generation technologies for smart healthcare: Challenges, vision, model, trends and future directions. Internet Technology Letters, page e145. [8] Chaolin Huang, Yeming Wang, Xingwang Li, Lili Ren, Jianping Zhao, Yi Hu, Li Zhang, Guohui Fan, Jiuyang Xu, Xiaoying Gu, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. The Lancet, 395(10223):497–506, 2020.