Cleft lip and palate is an abnormal separation of tissues in the oral-facial region that occurs during fetal development. It can be caused by genetic factors, viruses, or other toxins. Symptoms include separation of the lip or palate, nasal distortion, ear infections, feeding difficulties, and speech and dental problems. Treatment involves surgery to repair the cleft, as well as speech therapy and orthodontics. Surgical repair of the cleft lip is usually done at 3-9 months of age, while cleft palate repair is typically between 18-24 months. Non-surgical treatments like dental obturators may also be used. Nursing care focuses on safe feeding and preventing aspiration during intake.
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Management of Orofacial Cleft Dr. Sunil (2).pptxManagement of Orofacial Cleft Dr. Sunil (2).pptxManagement of Orofacial Cleft Dr. Sunil (2).pptxManagement of Orofacial Cleft Dr. Sunil (2).pptx
Management of Orofacial Cleft Dr. Sunil (2).pptx Management of Orofacial Clef...ssuser12303b
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Cleft lip and palate /certified fixed orthodontic courses by Indian dental ac...Indian dental academy
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principles of Orthodontic management of cleft lip and palatejonathan kiprop
pathophysiology of clefting....embryological basis
management of cleft lip and cleft palate- orthodontic consideration
timing and sequencing of treatment
primary verses secondary alveolar grafting
Cleft lip and palate /certified fixed orthodontic courses by Indian dental ac...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
principles of Orthodontic management of cleft lip and palatejonathan kiprop
pathophysiology of clefting....embryological basis
management of cleft lip and cleft palate- orthodontic consideration
timing and sequencing of treatment
primary verses secondary alveolar grafting
India Clinical Trials Market: Industry Size and Growth Trends [2030] Analyzed...Kumar Satyam
According to TechSci Research report, "India Clinical Trials Market- By Region, Competition, Forecast & Opportunities, 2030F," the India Clinical Trials Market was valued at USD 2.05 billion in 2024 and is projected to grow at a compound annual growth rate (CAGR) of 8.64% through 2030. The market is driven by a variety of factors, making India an attractive destination for pharmaceutical companies and researchers. India's vast and diverse patient population, cost-effective operational environment, and a large pool of skilled medical professionals contribute significantly to the market's growth. Additionally, increasing government support in streamlining regulations and the growing prevalence of lifestyle diseases further propel the clinical trials market.
Growing Prevalence of Lifestyle Diseases
The rising incidence of lifestyle diseases such as diabetes, cardiovascular diseases, and cancer is a major trend driving the clinical trials market in India. These conditions necessitate the development and testing of new treatment methods, creating a robust demand for clinical trials. The increasing burden of these diseases highlights the need for innovative therapies and underscores the importance of India as a key player in global clinical research.
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Defecation
Normal defecation begins with movement in the left colon, moving stool toward the anus. When stool reaches the rectum, the distention causes relaxation of the internal sphincter and an awareness of the need to defecate. At the time of defecation, the external sphincter relaxes, and abdominal muscles contract, increasing intrarectal pressure and forcing the stool out
The Valsalva maneuver exerts pressure to expel faeces through a voluntary contraction of the abdominal muscles while maintaining forced expiration against a closed airway. Patients with cardiovascular disease, glaucoma, increased intracranial pressure, or a new surgical wound are at greater risk for cardiac dysrhythmias and elevated blood pressure with the Valsalva maneuver and need to avoid straining to pass the stool.
Normal defecation is painless, resulting in passage of soft, formed stool
CONSTIPATION
Constipation is a symptom, not a disease. Improper diet, reduced fluid intake, lack of exercise, and certain medications can cause constipation. For example, patients receiving opiates for pain after surgery often require a stool softener or laxative to prevent constipation. The signs of constipation include infrequent bowel movements (less than every 3 days), difficulty passing stools, excessive straining, inability to defecate at will, and hard feaces
IMPACTION
Fecal impaction results from unrelieved constipation. It is a collection of hardened feces wedged in the rectum that a person cannot expel. In cases of severe impaction the mass extends up into the sigmoid colon.
DIARRHEA
Diarrhea is an increase in the number of stools and the passage of liquid, unformed feces. It is associated with disorders affecting digestion, absorption, and secretion in the GI tract. Intestinal contents pass through the small and large intestine too quickly to allow for the usual absorption of fluid and nutrients. Irritation within the colon results in increased mucus secretion. As a result, feces become watery, and the patient is unable to control the urge to defecate. Normally an anal bag is safe and effective in long-term treatment of patients with fecal incontinence at home, in hospice, or in the hospital. Fecal incontinence is expensive and a potentially dangerous condition in terms of contamination and risk of skin ulceration
HEMORRHOIDS
Hemorrhoids are dilated, engorged veins in the lining of the rectum. They are either external or internal.
FLATULENCE
As gas accumulates in the lumen of the intestines, the bowel wall stretches and distends (flatulence). It is a common cause of abdominal fullness, pain, and cramping. Normally intestinal gas escapes through the mouth (belching) or the anus (passing of flatus)
FECAL INCONTINENCE
Fecal incontinence is the inability to control passage of feces and gas from the anus. Incontinence harms a patient’s body image
PREPARATION AND GIVING OF LAXATIVESACCORDING TO POTTER AND PERRY,
An enema is the instillation of a solution into the rectum and sig
Navigating Challenges: Mental Health, Legislation, and the Prison System in B...Guillermo Rivera
This conference will delve into the intricate intersections between mental health, legal frameworks, and the prison system in Bolivia. It aims to provide a comprehensive overview of the current challenges faced by mental health professionals working within the legislative and correctional landscapes. Topics of discussion will include the prevalence and impact of mental health issues among the incarcerated population, the effectiveness of existing mental health policies and legislation, and potential reforms to enhance the mental health support system within prisons.
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Global launch of the Healthy Ageing and Prevention Index 2nd wave – alongside...ILC- UK
The Healthy Ageing and Prevention Index is an online tool created by ILC that ranks countries on six metrics including, life span, health span, work span, income, environmental performance, and happiness. The Index helps us understand how well countries have adapted to longevity and inform decision makers on what must be done to maximise the economic benefits that comes with living well for longer.
Alongside the 77th World Health Assembly in Geneva on 28 May 2024, we launched the second version of our Index, allowing us to track progress and give new insights into what needs to be done to keep populations healthier for longer.
The speakers included:
Professor Orazio Schillaci, Minister of Health, Italy
Dr Hans Groth, Chairman of the Board, World Demographic & Ageing Forum
Professor Ilona Kickbusch, Founder and Chair, Global Health Centre, Geneva Graduate Institute and co-chair, World Health Summit Council
Dr Natasha Azzopardi Muscat, Director, Country Health Policies and Systems Division, World Health Organisation EURO
Dr Marta Lomazzi, Executive Manager, World Federation of Public Health Associations
Dr Shyam Bishen, Head, Centre for Health and Healthcare and Member of the Executive Committee, World Economic Forum
Dr Karin Tegmark Wisell, Director General, Public Health Agency of Sweden
CRISPR-Cas9, a revolutionary gene-editing tool, holds immense potential to reshape medicine, agriculture, and our understanding of life. But like any powerful tool, it comes with ethical considerations.
Unveiling CRISPR: This naturally occurring bacterial defense system (crRNA & Cas9 protein) fights viruses. Scientists repurposed it for precise gene editing (correction, deletion, insertion) by targeting specific DNA sequences.
The Promise: CRISPR offers exciting possibilities:
Gene Therapy: Correcting genetic diseases like cystic fibrosis.
Agriculture: Engineering crops resistant to pests and harsh environments.
Research: Studying gene function to unlock new knowledge.
The Peril: Ethical concerns demand attention:
Off-target Effects: Unintended DNA edits can have unforeseen consequences.
Eugenics: Misusing CRISPR for designer babies raises social and ethical questions.
Equity: High costs could limit access to this potentially life-saving technology.
The Path Forward: Responsible development is crucial:
International Collaboration: Clear guidelines are needed for research and human trials.
Public Education: Open discussions ensure informed decisions about CRISPR.
Prioritize Safety and Ethics: Safety and ethical principles must be paramount.
CRISPR offers a powerful tool for a better future, but responsible development and addressing ethical concerns are essential. By prioritizing safety, fostering open dialogue, and ensuring equitable access, we can harness CRISPR's power for the benefit of all. (2998 characters)
One of the most developed cities of India, the city of Chennai is the capital of Tamilnadu and many people from different parts of India come here to earn their bread and butter. Being a metropolitan, the city is filled with towering building and beaches but the sad part as with almost every Indian city
2. Definition
◦A cleft lip or palate
is an abnormal
separation in the
oral-facial region that
happens because tissue
of the mouth or lip
does not form
correctly in fetal
development.
3. Causes
◦Other birth defects
may cause cleft lip or
palate
◦Mutated Inherited
Genes (gene=top,
mutation=bottom)
◦Teratogens (viruses or
other toxins that cause
abnormalities in the fetus)
4. Symptoms
◦Separation of the
lip (picture)
◦Separation of
the palate (roof
of the mouth)
◦Nasal distortion
◦Recurring
ear infections
5. Symptoms (cont.)
◦Failure to gain
weight
◦Nasal
regurgitation when
bottle feeding
◦Poor speech
◦Misaligned teeth
◦Growth
retardation
(picture)
8. PATHOPHYSIOLOGY
DUE TO THE ETIOLOGICAL FACTORS
FAILURE OR INCOMPLETE UNION OF THE
EMBRYONIC STRUCTURE OF THE FACE
THE PALATILE PROCESS FUSE ABOUT ONE
MONTH LATER
CLEFT LIP & CLEFT PALATE
13. First Stage-treatment
◦The first part of the
process is surgery.
Surgery is done when
a child is at 3 to 9
months of age. Unless
there is extensive nasal
damage, no more than
one surgery is needed.
(before and after
picture)
15. Second Stage-therapy
◦The next stage is
therapy. Because of
surgery being done so
early hopefully speech
will form correctly but
because the child has
to adapt, therapy is
advised.
16. Final Stage-orthodontics
◦The final stage of
treatment is
orthodontics. If as the
child gets older teeth
are not straight you
should see an
orthodontist for
treatment (braces).
17. Airway Problems
◦More common in Cleft Palate patients with concomitant structural or
functional anomalies.
◦e.g. Pierre-Robin Sequence
◦Micrognathia, Cleft Palate, Glossoptosis
◦May develop airway distress from tongue becoming lodged in palatal defect
18. Surgical Repair- Cleft Lip
◦Lip Adhesions-
◦2 weeks of age
◦Converts complete cleft into incomplete cleft
◦Serves as temporizing measure for those with feeding problems
◦May interfere with definitive lip repair
◦Less often needed in recent years due to wider variety of specialty feeding
nipples
19. Surgical Repair- Cleft Lip
◦Cleft lip repaired at 10 weeks
◦Rotation-advancement method- Most common in the
U.S.
◦Nine Landmarks
◦Rotation Flap cuts made first
◦Advancement cuts made next
◦Cleft side nasal ala cuts made last
20. Surgical Repair- Cleft Palate
◦Several Techniques- Trend is towards less scarring and less tension on palate
◦Scarring of palate may cause impaired mid-facial growth(alveolar
arch collapse, midface retrusion, malocclusion)
◦Facial growth may be less affected if surgery is delayed until 18-24 months,
but feeding, speech, socialization may suffer.
21. Surgical Repair- Cleft Palate
◦Bardach Method- Two Flap technique
◦Medial incisions made, which separate oral and nasal
mucosa
◦Lateral incisions made at junction of palate and alveolar
ridge
◦Elevate flaps, preserve greater palatine artery.
◦Detach velar muscles from posterior palate
◦Close in 3 layers
22.
23. Non-Surgical Treatment
◦Dental Obturator
◦For high-risk patients or those that refuse surgery.
◦Advantage- High rate of closure
◦Disadvantage- Need to wear a prosthesis, and need to modify prosthesis as
child grows.
24. Nursing management:
□Main problems in this condition is feeding and risk
for aspiration.
Feeding:
□Use soft nipples with large hole feeding bottles (Aseptosyringe,
Medicine broker ,spoons ect ).
□Always keep Childs head elevated while feeding
□Use ESSR technique:
E Enlarge nipple.
S Stimulate sucking reflex.
S Swallow the fluid appropriately.
R Rest after feeding.
25. Conclusions
◦Cleft Lip and Palate are common congenital deformities that often affect
speech, hearing, and cosmesis; and may at times lead to airway compromise.
◦The otolaryngologist is a key member of the cleft palate team, and is in
a unique position to identify and manage many of these problems .