Cholinergic agonists are chemicals that act at acetylcholine receptor sites to mimic the effects of acetylcholine. There are two types - direct-acting agonists which occupy acetylcholine receptor sites, and indirect-acting agonists which prevent the breakdown of acetylcholine by inhibiting acetylcholinesterase. Direct-acting agonists are used to treat urinary retention and glaucoma, while indirect-acting agonists are used for myasthenia gravis and Alzheimer's disease by prolonging acetylcholine stimulation. Indirect agonists can interact with NSAIDs.
This presentation covers an introduction to Autonomic Nervous System.. only enough to understand the actions of cholinergic and anticholinergic drugs. This presentation does not include anticholinergic drugs.
This presentation deals with the various cholinergic (acetylcholine) and anti-cholinergic drugs (atropine) alongwith a brief description of the various muscarinic receptors and nicotinic receptors. Also, it includes various agonists & antagonists with a brief description of organophosphorous poisoning at the end.