Polygenic inheritance is when a single trait is controlled by multiple genes. Most human traits related to size, shape, and color are polygenic. A cross between parents that are heterozygous for three genes (AaBbCc x AaBbCc) would produce offspring with different combinations of dominant and recessive alleles, leading to a range of phenotypes. The number of dominant alleles an individual possesses determines how strongly or darkly a polygenic trait is expressed.