This study investigated the phytochemicals and pharmacological importance of Erythrina senegalensis. The root was extracted sequentially using hexane, ethyl acetate, and methanol. Methanol extraction yielded the highest percentage (4.28%), followed by ethyl acetate (3.62%) and hexane (2.84%). Phytochemical screening found alkaloids, flavonoids, anthraquinones, phenols, quinones, steroids, saponins, tannins, terpenoids, and xanthoproteins present. The plant is used traditionally to treat jaundice, gonorrhea, dysentery, colitis, and malaria. Previous studies found the root extract