General pharmacological terms which will be helpful to Pharmacy Students in their Entrance Exam Preparation. i.e GPAT. In this PPT you can find many pharmacological terms which will be helpful to understand the basic knowledge about Pharmacology.
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Presence of multiplying bacteria in blood as emboli which spread and lodge in different organs in the body like liver
Lungs, kidneys, spleen, brain causing pyaemic abscess.
- Ludwig's angina is a rapidly progressive polymicrobial cellulitis of the sublingual and submandibular spaces, involving the floor of the mouth and suprahyoid area of the neck bilaterally.
- It is commonly caused by dental infections and presents with diffuse painful swelling and woody induration of the mouth and anterior neck, which can lead to airway obstruction if not treated promptly with antibiotics and potentially tracheostomy.
- Complications include laryngeal edema, mediastinitis, sepsis and spread of infection to deep spaces which can become life-threatening.
The document discusses various diseases of the kidney. It begins by describing the normal structure and functions of the kidney. It then discusses various glomerular and non-glomerular diseases in detail, including their classification, clinical manifestations, and microscopic pathology. Some of the diseases covered include glomerulonephritis, pyelonephritis, diabetic nephropathy, benign and malignant nephrosclerosis, and hydronephrosis.
This document discusses scleroderma, a chronic autoimmune disease characterized by fibrosis of the skin and internal organs. It defines the two main types as limited scleroderma, which affects the hands, face and forearms, and diffuse scleroderma, which affects the whole body. Raynaud's phenomenon, skin thickening, gastrointestinal issues, lung fibrosis and pulmonary hypertension are common clinical features. The document provides details on pathogenesis, prevalence, risk factors, clinical assessment criteria and organ-specific complications of scleroderma.
Membranous GN
MOST COMMON cause is idiopathic (85%); peak age 30-50; male:female, 2:1
May be secondary to:
Drugs-captopril, penicillamine, gold, mercury, trimethadione, NSAIDS
Infections-malaria (P. malariae), leprosy, schistosomiasis, syphilis, hepatitis B and C, filariasis, hydatid disease and enterococcal endocarditis
Diseases-malignancy (Carcinoma of breast, lung, colon, stomach, and esophagus) melanoma, renal cell CA, SLE, sarcoidosis, diabetes, thyroiditis, sickle cell anemia, Crohn’s disease
This document discusses tubulointerstitial disorders, which are diseases affecting the renal tubules and interstitium. Tubulointerstitial disorders are distinguished from glomerular diseases by the absence of nephritic or nephrotic syndrome and the presence of tubular dysfunction manifesting as defects in concentration ability, polyuria, nocturia, and metabolic acidosis. Common tubulointerstitial disorders discussed include acute tubular necrosis, tubulointerstitial nephritis, pyelonephritis, drug-induced tubulointerstitial nephritis, analgesic nephropathy, and diseases causing hypercalcemia and nephrocalcinosis.
The document discusses the normal composition and characteristics of cerebrospinal fluid (CSF) as well as abnormalities that can indicate various medical conditions:
- CSF normally contains low levels of proteins, glucose, and cells while maintaining slightly acidic pH, clarity and specific gravity.
- Bacterial, fungal and tuberculous meningitis can be indicated by turbid CSF, high white blood cell count often with neutrophils, low glucose, and elevated proteins.
- Viral meningitis presents with clear CSF, mild increase in cells and proteins, and normal glucose.
Several diseases are caused by exotoxins produced by bacteria, including botulism caused by Clostridium botulinum exotoxin which prevents nerve impulses and causes flaccid paralysis. Tetanus caused by Clostridium tetani exotoxin blocks muscle contraction pathways resulting in uncontrollable muscle spasms. Diseases like cholera, traveler's diarrhea, and some food poisonings involve enterotoxins secreted by bacteria such as Vibrio cholerae and enterotoxigenic Escherichia coli which cause secretion of fluids leading to diarrhea.
Presence of multiplying bacteria in blood as emboli which spread and lodge in different organs in the body like liver
Lungs, kidneys, spleen, brain causing pyaemic abscess.
- Ludwig's angina is a rapidly progressive polymicrobial cellulitis of the sublingual and submandibular spaces, involving the floor of the mouth and suprahyoid area of the neck bilaterally.
- It is commonly caused by dental infections and presents with diffuse painful swelling and woody induration of the mouth and anterior neck, which can lead to airway obstruction if not treated promptly with antibiotics and potentially tracheostomy.
- Complications include laryngeal edema, mediastinitis, sepsis and spread of infection to deep spaces which can become life-threatening.
The document discusses various diseases of the kidney. It begins by describing the normal structure and functions of the kidney. It then discusses various glomerular and non-glomerular diseases in detail, including their classification, clinical manifestations, and microscopic pathology. Some of the diseases covered include glomerulonephritis, pyelonephritis, diabetic nephropathy, benign and malignant nephrosclerosis, and hydronephrosis.
This document discusses scleroderma, a chronic autoimmune disease characterized by fibrosis of the skin and internal organs. It defines the two main types as limited scleroderma, which affects the hands, face and forearms, and diffuse scleroderma, which affects the whole body. Raynaud's phenomenon, skin thickening, gastrointestinal issues, lung fibrosis and pulmonary hypertension are common clinical features. The document provides details on pathogenesis, prevalence, risk factors, clinical assessment criteria and organ-specific complications of scleroderma.
Membranous GN
MOST COMMON cause is idiopathic (85%); peak age 30-50; male:female, 2:1
May be secondary to:
Drugs-captopril, penicillamine, gold, mercury, trimethadione, NSAIDS
Infections-malaria (P. malariae), leprosy, schistosomiasis, syphilis, hepatitis B and C, filariasis, hydatid disease and enterococcal endocarditis
Diseases-malignancy (Carcinoma of breast, lung, colon, stomach, and esophagus) melanoma, renal cell CA, SLE, sarcoidosis, diabetes, thyroiditis, sickle cell anemia, Crohn’s disease
This document discusses tubulointerstitial disorders, which are diseases affecting the renal tubules and interstitium. Tubulointerstitial disorders are distinguished from glomerular diseases by the absence of nephritic or nephrotic syndrome and the presence of tubular dysfunction manifesting as defects in concentration ability, polyuria, nocturia, and metabolic acidosis. Common tubulointerstitial disorders discussed include acute tubular necrosis, tubulointerstitial nephritis, pyelonephritis, drug-induced tubulointerstitial nephritis, analgesic nephropathy, and diseases causing hypercalcemia and nephrocalcinosis.
The document discusses the normal composition and characteristics of cerebrospinal fluid (CSF) as well as abnormalities that can indicate various medical conditions:
- CSF normally contains low levels of proteins, glucose, and cells while maintaining slightly acidic pH, clarity and specific gravity.
- Bacterial, fungal and tuberculous meningitis can be indicated by turbid CSF, high white blood cell count often with neutrophils, low glucose, and elevated proteins.
- Viral meningitis presents with clear CSF, mild increase in cells and proteins, and normal glucose.
Several diseases are caused by exotoxins produced by bacteria, including botulism caused by Clostridium botulinum exotoxin which prevents nerve impulses and causes flaccid paralysis. Tetanus caused by Clostridium tetani exotoxin blocks muscle contraction pathways resulting in uncontrollable muscle spasms. Diseases like cholera, traveler's diarrhea, and some food poisonings involve enterotoxins secreted by bacteria such as Vibrio cholerae and enterotoxigenic Escherichia coli which cause secretion of fluids leading to diarrhea.
This document lists and defines common medical specialties, general medical terms, body parts, medical prefixes, and terms related to various body systems and diseases. It provides definitions for over 200 terms related to anatomy, pathology, pharmacology, psychiatry, cardiology, respiratory systems, rheumatology, and other areas of medicine. Specialties are defined like cardiology as the study of the heart and its diseases. Medical terms include definitions for concepts like antibodies, antigens, and symptoms. Body parts are identified by location like anterior, posterior, and proximal. Prefixes indicate relation to organ systems.
This document defines and describes various medical terms related to microbiology, infections, diseases, and related topics. It provides definitions for terms like abrasion, abscess, acute, aerobic, anaerobic, and more. The definitions cover a wide range of topics including types of infections, symptoms, medical procedures, modes of transmission, sterilization processes, and more.
This document discusses disorders of the adrenal glands, including hyperactivity and hypoactivity. Hyperactivity disorders include Cushing's syndrome, hyperaldosteronism, and adrenogenital syndrome. Cushing's syndrome can be caused by excessive cortisol secretion from the pituitary gland (Cushing's disease) or the adrenal glands (Cushing's syndrome). Symptoms include obesity, muscle weakness, osteoporosis, hyperglycemia, and hypertension. Hypoactivity disorders include chronic and acute adrenal insufficiency (Addison's disease and Addisonian crisis), which can be caused by adrenal gland failure or damage. Signs of Addison's disease include pigmentation, muscular weakness, hypotension,
presentation on CHF,orchitis,shock,anemiaRoshan paudel
This document provides information on various types of shock, congestive heart failure, anaemia, and orchitis. It discusses the etiology, pathophysiology, clinical signs, diagnosis, and management of each condition. The main types of shock described are hypovolemic, cardiogenic, and distributive shock. Congestive heart failure results from the heart's inability to pump sufficiently. The signs of left and right sided heart failure are outlined. Anaemia is classified based on red blood cell morphology and causes. Orchitis is testicular inflammation that can result from infection, trauma, or parasites.
Edema is the abnormal accumulation of fluid in body tissues. It can occur intracellularly or extracellularly. Intracellular edema is caused by fluid accumulation inside cells due to issues like low sodium levels or metabolic problems. Extracellular edema has multiple causes, including increased capillary permeability from infections or burns; increased capillary pressure from kidney issues or high venous pressure; decreased plasma proteins from kidney damage or burns; or blockages in lymph vessels from cancer, infections, or surgery. The lymphatic system plays an important role in fluid balance, and lymphedema occurs when lymph vessels fail to return fluid and proteins to the bloodstream.
This document discusses cell injury and cellular adaptations. It begins by defining cell injury and describing some common causes, including hypoxia, physical agents, chemicals, microbes, nutrition imbalances, and diseases. It then explains the pathogenesis and morphology of reversible and irreversible cell injury. Finally, it covers various types of cellular adaptations to injury, such as atrophy, hypertrophy, hyperplasia, metaplasia, and dysplasia.
The document discusses edema and fluid balance in the body. It describes the normal circulation of fluid between blood and tissues, mediated by hydrostatic and oncotic pressures. Edema occurs when there is increased hydrostatic pressure, decreased oncotic pressure, increased capillary permeability, or impaired lymphatic drainage. Specific types of edema discussed include cardiac, hepatic, pulmonary, cerebral, and lymphatic edema. Sites of common edema and clinical significance are also reviewed.
This document discusses diseases of the adrenal cortex, including hyperadrenalism and hypoadrenalism. It describes three hyperadrenal clinical syndromes caused by excess production of cortisol, mineralocorticoids, or androgens. Cushing syndrome is discussed in depth, outlining its causes such as Cushing disease and ectopic ACTH secretion. Hyperaldosteronism and adrenogenital syndromes are also summarized. Hypoadrenalism includes primary and secondary causes, with Addison disease and acute adrenal crisis covered as examples of primary hypoadrenalism.
The document discusses Addison's disease and Cushing's syndrome. It begins by describing the adrenal glands and their role in producing steroid hormones. It then covers the zones of the adrenal cortex and their hormone productions. Next, it explains Addison's disease as resulting from hypoadrenalism and describes its symptoms and treatment. It also outlines Cushing's syndrome as caused by hypersecretion of hormones and notes its physiological effects and treatment options.
This document discusses abnormalities of adrenocortical secretion, including Cushing's syndrome caused by hypersecretion of cortisol from the adrenal cortex or pituitary gland, and Addison's disease caused by hypoadrenalism and deficiency of corticosteroids. Cushing's syndrome results in obesity, high blood sugar, and other signs. It is diagnosed through tests of blood cortisol and urine steroids. Treatment depends on the underlying cause but may include drugs, surgery, or radiation. Addison's disease causes weakness, dehydration, low blood pressure, and pigmentation due to excess ACTH, and is treated with glucocorticoid and mineralocorticoid replacement therapy.
Septicemia and toxemia with pictures
Septicemia is an infection that occurs when bacteria enter the bloodstream and spread
ETIOLOGY: caused by infection with bacteria, viruses or fungi.
Septicemia is a serious infection in the blood and lymphatic system.
Signs and symptoms of septicemia can include fever, chills, dehydration, shock, shortness of breath, coughing up blood, fatigue, edema in the head, neck, and throat, hypersalivation and death
Lesions: In animals, hemorrhagic septicemia can cause lesions in the respiratory tract, lymph nodes, and other organs
septicemia can cause damage to multiple organs, including the lungs, kidneys, and liver
Diagnosis: clinical signs, blood tests, and other laboratory tests to identify the underlying infection
Treatment
Oxygen therapy
Fluid therapy
Sometimes emergency surgery
Appropriate antibiotic therapy should be based on culture and sensitivity results to identify effective antibiotics like Ampicillin, Cefazolin, Vancomycin, Ciprofloxacin
Lesions: In animals, hemorrhagic septicemia can cause lesions in the respiratory tract, lymph nodes, and other organs
septicemia can cause damage to multiple organs, including the lungs, kidneys, and liver
Diagnosis: clinical signs, blood tests, and other laboratory tests to identify the underlying infection
Treatment
Oxygen therapy
Fluid therapy
Sometimes emergency surgery
Appropriate antibiotic therapy should be based on culture and sensitivity results to identify effective antibiotics like Ampicillin, Cefazolin, Vancomycin, Ciprofloxacin
Read more
Bacterial causes of septicemia
Chemical causes of toxaemia
The document discusses the anatomy and functions of the adrenal glands and their cortex and medulla. It describes various adrenal disorders including adrenocortical hyperfunction (Cushing's syndrome, Conn's syndrome, adrenogenital syndrome), hypofunction (primary and secondary adrenocortical insufficiency, hypoaldosteronism), and tumours (cortical adenoma and carcinoma, pheochromocytoma, neuroblastoma). Cushing's syndrome is most often caused by a pituitary adenoma and results in central obesity, high blood pressure, and skin changes. Conn's syndrome is due to aldosterone-secreting adrenal adenoma and causes hypertension and low potassium levels.
This document discusses various types of excessive sweating conditions (hyperhidrosis) including their causes, presentations, and treatments. It describes primary cortical (emotional) hyperhidrosis which commonly affects the axillae and palms. Secondary causes include hyperhidrosis related to the hypothalamus or gustatory system. Treatment options mentioned are topical antiperspirants, oral medications like glycopyrrolate, and botulinum toxin injections for select cases.
Cirrhosis is a consequence of chronic liver disease characterized by the replacement of liver tissue with scar tissue. It is caused most commonly by alcoholism, hepatitis B and C, and fatty liver disease. Cirrhosis results in the progressive loss of liver function. Once cirrhosis occurs, the damage is generally irreversible and treatment focuses on preventing further progression and complications such as edema, ascites, bleeding from esophageal varices, and liver cancer.
Pathophysiology of asphyxia & drowningchetan samra
This document discusses pathophysiology of asphyxia. It begins by defining asphyxia and describing the normal levels of oxygen in the blood. It then discusses Gordon's classification of anoxia and the different types. Histotoxic anoxia is subdivided and explained further. The stages of asphyxia and vicious cycle are outlined. Asphyxial triad of cyanosis, congestion/edema and petechiae is defined. Violent asphyxial deaths like hanging, strangulation and drowning are described in detail including the post-mortem findings associated with each type. Histological changes and effects of asphyxia on the brain are also summarized.
Pathophysiology of asphyxia & drowningchetan samra
This document discusses pathophysiology of asphyxia. It begins by defining asphyxia and describing the normal levels of oxygen in the blood. It then discusses Gordon's classification of anoxia and the different types. Histotoxic anoxia is subdivided and explained further. The stages of asphyxia and vicious cycle are outlined. Asphyxial triad of cyanosis, congestion/edema and petechiae is defined. Violent asphyxial deaths like hanging, strangulation and drowning are described along with their post-mortem findings. Specific tests for drowning like diatom test are also mentioned.
1. Fat embolism syndrome is a serious manifestation of fat embolism that can cause multi-system dysfunction, most commonly affecting the lungs and brain.
2. It occurs most often after long bone fractures, especially femur fractures, when fat droplets enter the bloodstream and lodge in the pulmonary capillaries or brain vasculature.
3. Clinical features include a triad of respiratory distress, neurological changes like confusion, and petechial rash. Diagnosis is based on clinical criteria and imaging may show changes in the lungs and brain. Treatment is supportive with oxygen, ventilation if needed, IV fluids and steroids. Prognosis is generally good if respiratory failure can be prevented.
Clinical Research Regulation in European Union ShantanuThakre3
The document discusses clinical research regulations in the European Union. It provides information on the aim of the European Medicines Agency (EMA) in regulating clinical trials to protect subjects' rights and safety. It describes the EMA's role in ensuring good clinical practice standards across the European Economic Area. It also summarizes key points of the new Clinical Trials Regulation, including requirements for authorization, informed consent, and conducting trials on vulnerable groups. Finally, it discusses the Clinical Trials Information System that will support application and oversight of trials under the new Regulation.
Second Party Audit and External Third Party AuditShantanuThakre3
Second Party Audit:- Second-party audit is when a company performs an audit of a supplier to ensure that they are meeting the requirements specified in the contract.
External Third Party Audit:-
A third-party audit occurs when a company has decided that they want to create a Quality Management System (QMS) that conforms to a standard set of requirements, such as ISO 9001 and hire an independent auditing company to perform an audit to verify that the company has succeeded in meeting these standards.
This document lists and defines common medical specialties, general medical terms, body parts, medical prefixes, and terms related to various body systems and diseases. It provides definitions for over 200 terms related to anatomy, pathology, pharmacology, psychiatry, cardiology, respiratory systems, rheumatology, and other areas of medicine. Specialties are defined like cardiology as the study of the heart and its diseases. Medical terms include definitions for concepts like antibodies, antigens, and symptoms. Body parts are identified by location like anterior, posterior, and proximal. Prefixes indicate relation to organ systems.
This document defines and describes various medical terms related to microbiology, infections, diseases, and related topics. It provides definitions for terms like abrasion, abscess, acute, aerobic, anaerobic, and more. The definitions cover a wide range of topics including types of infections, symptoms, medical procedures, modes of transmission, sterilization processes, and more.
This document discusses disorders of the adrenal glands, including hyperactivity and hypoactivity. Hyperactivity disorders include Cushing's syndrome, hyperaldosteronism, and adrenogenital syndrome. Cushing's syndrome can be caused by excessive cortisol secretion from the pituitary gland (Cushing's disease) or the adrenal glands (Cushing's syndrome). Symptoms include obesity, muscle weakness, osteoporosis, hyperglycemia, and hypertension. Hypoactivity disorders include chronic and acute adrenal insufficiency (Addison's disease and Addisonian crisis), which can be caused by adrenal gland failure or damage. Signs of Addison's disease include pigmentation, muscular weakness, hypotension,
presentation on CHF,orchitis,shock,anemiaRoshan paudel
This document provides information on various types of shock, congestive heart failure, anaemia, and orchitis. It discusses the etiology, pathophysiology, clinical signs, diagnosis, and management of each condition. The main types of shock described are hypovolemic, cardiogenic, and distributive shock. Congestive heart failure results from the heart's inability to pump sufficiently. The signs of left and right sided heart failure are outlined. Anaemia is classified based on red blood cell morphology and causes. Orchitis is testicular inflammation that can result from infection, trauma, or parasites.
Edema is the abnormal accumulation of fluid in body tissues. It can occur intracellularly or extracellularly. Intracellular edema is caused by fluid accumulation inside cells due to issues like low sodium levels or metabolic problems. Extracellular edema has multiple causes, including increased capillary permeability from infections or burns; increased capillary pressure from kidney issues or high venous pressure; decreased plasma proteins from kidney damage or burns; or blockages in lymph vessels from cancer, infections, or surgery. The lymphatic system plays an important role in fluid balance, and lymphedema occurs when lymph vessels fail to return fluid and proteins to the bloodstream.
This document discusses cell injury and cellular adaptations. It begins by defining cell injury and describing some common causes, including hypoxia, physical agents, chemicals, microbes, nutrition imbalances, and diseases. It then explains the pathogenesis and morphology of reversible and irreversible cell injury. Finally, it covers various types of cellular adaptations to injury, such as atrophy, hypertrophy, hyperplasia, metaplasia, and dysplasia.
The document discusses edema and fluid balance in the body. It describes the normal circulation of fluid between blood and tissues, mediated by hydrostatic and oncotic pressures. Edema occurs when there is increased hydrostatic pressure, decreased oncotic pressure, increased capillary permeability, or impaired lymphatic drainage. Specific types of edema discussed include cardiac, hepatic, pulmonary, cerebral, and lymphatic edema. Sites of common edema and clinical significance are also reviewed.
This document discusses diseases of the adrenal cortex, including hyperadrenalism and hypoadrenalism. It describes three hyperadrenal clinical syndromes caused by excess production of cortisol, mineralocorticoids, or androgens. Cushing syndrome is discussed in depth, outlining its causes such as Cushing disease and ectopic ACTH secretion. Hyperaldosteronism and adrenogenital syndromes are also summarized. Hypoadrenalism includes primary and secondary causes, with Addison disease and acute adrenal crisis covered as examples of primary hypoadrenalism.
The document discusses Addison's disease and Cushing's syndrome. It begins by describing the adrenal glands and their role in producing steroid hormones. It then covers the zones of the adrenal cortex and their hormone productions. Next, it explains Addison's disease as resulting from hypoadrenalism and describes its symptoms and treatment. It also outlines Cushing's syndrome as caused by hypersecretion of hormones and notes its physiological effects and treatment options.
This document discusses abnormalities of adrenocortical secretion, including Cushing's syndrome caused by hypersecretion of cortisol from the adrenal cortex or pituitary gland, and Addison's disease caused by hypoadrenalism and deficiency of corticosteroids. Cushing's syndrome results in obesity, high blood sugar, and other signs. It is diagnosed through tests of blood cortisol and urine steroids. Treatment depends on the underlying cause but may include drugs, surgery, or radiation. Addison's disease causes weakness, dehydration, low blood pressure, and pigmentation due to excess ACTH, and is treated with glucocorticoid and mineralocorticoid replacement therapy.
Septicemia and toxemia with pictures
Septicemia is an infection that occurs when bacteria enter the bloodstream and spread
ETIOLOGY: caused by infection with bacteria, viruses or fungi.
Septicemia is a serious infection in the blood and lymphatic system.
Signs and symptoms of septicemia can include fever, chills, dehydration, shock, shortness of breath, coughing up blood, fatigue, edema in the head, neck, and throat, hypersalivation and death
Lesions: In animals, hemorrhagic septicemia can cause lesions in the respiratory tract, lymph nodes, and other organs
septicemia can cause damage to multiple organs, including the lungs, kidneys, and liver
Diagnosis: clinical signs, blood tests, and other laboratory tests to identify the underlying infection
Treatment
Oxygen therapy
Fluid therapy
Sometimes emergency surgery
Appropriate antibiotic therapy should be based on culture and sensitivity results to identify effective antibiotics like Ampicillin, Cefazolin, Vancomycin, Ciprofloxacin
Lesions: In animals, hemorrhagic septicemia can cause lesions in the respiratory tract, lymph nodes, and other organs
septicemia can cause damage to multiple organs, including the lungs, kidneys, and liver
Diagnosis: clinical signs, blood tests, and other laboratory tests to identify the underlying infection
Treatment
Oxygen therapy
Fluid therapy
Sometimes emergency surgery
Appropriate antibiotic therapy should be based on culture and sensitivity results to identify effective antibiotics like Ampicillin, Cefazolin, Vancomycin, Ciprofloxacin
Read more
Bacterial causes of septicemia
Chemical causes of toxaemia
The document discusses the anatomy and functions of the adrenal glands and their cortex and medulla. It describes various adrenal disorders including adrenocortical hyperfunction (Cushing's syndrome, Conn's syndrome, adrenogenital syndrome), hypofunction (primary and secondary adrenocortical insufficiency, hypoaldosteronism), and tumours (cortical adenoma and carcinoma, pheochromocytoma, neuroblastoma). Cushing's syndrome is most often caused by a pituitary adenoma and results in central obesity, high blood pressure, and skin changes. Conn's syndrome is due to aldosterone-secreting adrenal adenoma and causes hypertension and low potassium levels.
This document discusses various types of excessive sweating conditions (hyperhidrosis) including their causes, presentations, and treatments. It describes primary cortical (emotional) hyperhidrosis which commonly affects the axillae and palms. Secondary causes include hyperhidrosis related to the hypothalamus or gustatory system. Treatment options mentioned are topical antiperspirants, oral medications like glycopyrrolate, and botulinum toxin injections for select cases.
Cirrhosis is a consequence of chronic liver disease characterized by the replacement of liver tissue with scar tissue. It is caused most commonly by alcoholism, hepatitis B and C, and fatty liver disease. Cirrhosis results in the progressive loss of liver function. Once cirrhosis occurs, the damage is generally irreversible and treatment focuses on preventing further progression and complications such as edema, ascites, bleeding from esophageal varices, and liver cancer.
Pathophysiology of asphyxia & drowningchetan samra
This document discusses pathophysiology of asphyxia. It begins by defining asphyxia and describing the normal levels of oxygen in the blood. It then discusses Gordon's classification of anoxia and the different types. Histotoxic anoxia is subdivided and explained further. The stages of asphyxia and vicious cycle are outlined. Asphyxial triad of cyanosis, congestion/edema and petechiae is defined. Violent asphyxial deaths like hanging, strangulation and drowning are described in detail including the post-mortem findings associated with each type. Histological changes and effects of asphyxia on the brain are also summarized.
Pathophysiology of asphyxia & drowningchetan samra
This document discusses pathophysiology of asphyxia. It begins by defining asphyxia and describing the normal levels of oxygen in the blood. It then discusses Gordon's classification of anoxia and the different types. Histotoxic anoxia is subdivided and explained further. The stages of asphyxia and vicious cycle are outlined. Asphyxial triad of cyanosis, congestion/edema and petechiae is defined. Violent asphyxial deaths like hanging, strangulation and drowning are described along with their post-mortem findings. Specific tests for drowning like diatom test are also mentioned.
1. Fat embolism syndrome is a serious manifestation of fat embolism that can cause multi-system dysfunction, most commonly affecting the lungs and brain.
2. It occurs most often after long bone fractures, especially femur fractures, when fat droplets enter the bloodstream and lodge in the pulmonary capillaries or brain vasculature.
3. Clinical features include a triad of respiratory distress, neurological changes like confusion, and petechial rash. Diagnosis is based on clinical criteria and imaging may show changes in the lungs and brain. Treatment is supportive with oxygen, ventilation if needed, IV fluids and steroids. Prognosis is generally good if respiratory failure can be prevented.
Clinical Research Regulation in European Union ShantanuThakre3
The document discusses clinical research regulations in the European Union. It provides information on the aim of the European Medicines Agency (EMA) in regulating clinical trials to protect subjects' rights and safety. It describes the EMA's role in ensuring good clinical practice standards across the European Economic Area. It also summarizes key points of the new Clinical Trials Regulation, including requirements for authorization, informed consent, and conducting trials on vulnerable groups. Finally, it discusses the Clinical Trials Information System that will support application and oversight of trials under the new Regulation.
Second Party Audit and External Third Party AuditShantanuThakre3
Second Party Audit:- Second-party audit is when a company performs an audit of a supplier to ensure that they are meeting the requirements specified in the contract.
External Third Party Audit:-
A third-party audit occurs when a company has decided that they want to create a Quality Management System (QMS) that conforms to a standard set of requirements, such as ISO 9001 and hire an independent auditing company to perform an audit to verify that the company has succeeded in meeting these standards.
Ethics in Clinical Research and Historical Perspective of Nazi Trials, Nuremb...ShantanuThakre3
What is Ethics ?
The word ‘ethics’ is derived from the Greek word,
ethos, which means custom or character. Ethics is
the systematic study of values, so as to decide
what is right and what is wrong. Ethics is concerned
with what is good for individuals and society.
What is Clinical Research ?
Clinical Research is a branch of healthcare science that determines the safety and effectiveness of medications, devices, diagnostic products and treatment regimens intended for human use. These may be used for prevention, treatment, diagnosis or for relieving symptoms of a disease.
Importance of Ethics in Clinical Research :-
1. Ethics is important in clinical research because it keeps the researcher from committing errors while seeking knowledge and truth.
2. Ethical guidelines for clinical research were formulated only after discovery of inhumane behavior with participants during research experiments.
3. In clinical research human beings are involved, as opposed to animals, atoms or asteroids, as the object of study.
4. It focuses on improving human health and well-being, typically by identifying better methods to treat, cure or prevent illnesses.
5. The Ethics Committee stands as the bridge between the researcher and the ethical guidelines of the country
Intellectual Property Rights are legal rights governing the use of creations of the human mind. The recognition and protection of these rights is of recent origin. Patents, designs and trademarks are considered as industrial property.
The Trade Marks Registry was established in India in 1940 and presently it administers the Trade Marks Act, 1999 and the rules made thereunder. It acts as a resource and information Centre and is a facilitator in matters relating to trademarks in the country.
The objective of the Trade Marks Act, 1999 is to register trademarks applied for in the country and to provide for better protection of trademark for goods and services and also to prevent fraudulent use of the mark.
The main function of the Registry is to register trademarks which qualify for registration as per provisions of the Trade Marks Act and Rules, and to maintain the Register of trademarks.
Spectroscopy uses electromagnetic radiation to probe molecular structures and can be used for quantitative analysis. It examines properties like wavelength, frequency, and wave number. Different types of energy associated with molecules include translational, rotational, vibrational, and electronic. Spectroscopy analyzes these energies to determine molecular structure and composition.
Basic knowledge about Pharmacology which will be helpful in Academic and for GPAT exam. Brief description about Pharmacokinetics and Pharmacodynamic, clinical trials and some important definitions. Different types of drug administration.
Strategies for Effective Upskilling is a presentation by Chinwendu Peace in a Your Skill Boost Masterclass organisation by the Excellence Foundation for South Sudan on 08th and 09th June 2024 from 1 PM to 3 PM on each day.
A Strategic Approach: GenAI in EducationPeter Windle
Artificial Intelligence (AI) technologies such as Generative AI, Image Generators and Large Language Models have had a dramatic impact on teaching, learning and assessment over the past 18 months. The most immediate threat AI posed was to Academic Integrity with Higher Education Institutes (HEIs) focusing their efforts on combating the use of GenAI in assessment. Guidelines were developed for staff and students, policies put in place too. Innovative educators have forged paths in the use of Generative AI for teaching, learning and assessments leading to pockets of transformation springing up across HEIs, often with little or no top-down guidance, support or direction.
This Gasta posits a strategic approach to integrating AI into HEIs to prepare staff, students and the curriculum for an evolving world and workplace. We will highlight the advantages of working with these technologies beyond the realm of teaching, learning and assessment by considering prompt engineering skills, industry impact, curriculum changes, and the need for staff upskilling. In contrast, not engaging strategically with Generative AI poses risks, including falling behind peers, missed opportunities and failing to ensure our graduates remain employable. The rapid evolution of AI technologies necessitates a proactive and strategic approach if we are to remain relevant.
বাংলাদেশের অর্থনৈতিক সমীক্ষা ২০২৪ [Bangladesh Economic Review 2024 Bangla.pdf] কম্পিউটার , ট্যাব ও স্মার্ট ফোন ভার্সন সহ সম্পূর্ণ বাংলা ই-বুক বা pdf বই " সুচিপত্র ...বুকমার্ক মেনু 🔖 ও হাইপার লিংক মেনু 📝👆 যুক্ত ..
আমাদের সবার জন্য খুব খুব গুরুত্বপূর্ণ একটি বই ..বিসিএস, ব্যাংক, ইউনিভার্সিটি ভর্তি ও যে কোন প্রতিযোগিতা মূলক পরীক্ষার জন্য এর খুব ইম্পরট্যান্ট একটি বিষয় ...তাছাড়া বাংলাদেশের সাম্প্রতিক যে কোন ডাটা বা তথ্য এই বইতে পাবেন ...
তাই একজন নাগরিক হিসাবে এই তথ্য গুলো আপনার জানা প্রয়োজন ...।
বিসিএস ও ব্যাংক এর লিখিত পরীক্ষা ...+এছাড়া মাধ্যমিক ও উচ্চমাধ্যমিকের স্টুডেন্টদের জন্য অনেক কাজে আসবে ...
ISO/IEC 27001, ISO/IEC 42001, and GDPR: Best Practices for Implementation and...PECB
Denis is a dynamic and results-driven Chief Information Officer (CIO) with a distinguished career spanning information systems analysis and technical project management. With a proven track record of spearheading the design and delivery of cutting-edge Information Management solutions, he has consistently elevated business operations, streamlined reporting functions, and maximized process efficiency.
Certified as an ISO/IEC 27001: Information Security Management Systems (ISMS) Lead Implementer, Data Protection Officer, and Cyber Risks Analyst, Denis brings a heightened focus on data security, privacy, and cyber resilience to every endeavor.
His expertise extends across a diverse spectrum of reporting, database, and web development applications, underpinned by an exceptional grasp of data storage and virtualization technologies. His proficiency in application testing, database administration, and data cleansing ensures seamless execution of complex projects.
What sets Denis apart is his comprehensive understanding of Business and Systems Analysis technologies, honed through involvement in all phases of the Software Development Lifecycle (SDLC). From meticulous requirements gathering to precise analysis, innovative design, rigorous development, thorough testing, and successful implementation, he has consistently delivered exceptional results.
Throughout his career, he has taken on multifaceted roles, from leading technical project management teams to owning solutions that drive operational excellence. His conscientious and proactive approach is unwavering, whether he is working independently or collaboratively within a team. His ability to connect with colleagues on a personal level underscores his commitment to fostering a harmonious and productive workplace environment.
Date: May 29, 2024
Tags: Information Security, ISO/IEC 27001, ISO/IEC 42001, Artificial Intelligence, GDPR
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How to Manage Your Lost Opportunities in Odoo 17 CRMCeline George
Odoo 17 CRM allows us to track why we lose sales opportunities with "Lost Reasons." This helps analyze our sales process and identify areas for improvement. Here's how to configure lost reasons in Odoo 17 CRM
How to Fix the Import Error in the Odoo 17Celine George
An import error occurs when a program fails to import a module or library, disrupting its execution. In languages like Python, this issue arises when the specified module cannot be found or accessed, hindering the program's functionality. Resolving import errors is crucial for maintaining smooth software operation and uninterrupted development processes.
How to Add Chatter in the odoo 17 ERP ModuleCeline George
In Odoo, the chatter is like a chat tool that helps you work together on records. You can leave notes and track things, making it easier to talk with your team and partners. Inside chatter, all communication history, activity, and changes will be displayed.
Assessment and Planning in Educational technology.pptxKavitha Krishnan
In an education system, it is understood that assessment is only for the students, but on the other hand, the Assessment of teachers is also an important aspect of the education system that ensures teachers are providing high-quality instruction to students. The assessment process can be used to provide feedback and support for professional development, to inform decisions about teacher retention or promotion, or to evaluate teacher effectiveness for accountability purposes.
This presentation includes basic of PCOS their pathology and treatment and also Ayurveda correlation of PCOS and Ayurvedic line of treatment mentioned in classics.
Exploiting Artificial Intelligence for Empowering Researchers and Faculty, In...Dr. Vinod Kumar Kanvaria
Exploiting Artificial Intelligence for Empowering Researchers and Faculty,
International FDP on Fundamentals of Research in Social Sciences
at Integral University, Lucknow, 06.06.2024
By Dr. Vinod Kumar Kanvaria
Exploiting Artificial Intelligence for Empowering Researchers and Faculty, In...
Pharmacological terms
1. PHARMACOLOGICAL TERMS
a) Achyliagastria: Absence of gastric juice.
b) Achlorhydria: Absence of free hydrochloric acid in gastric juice.
c) Academia: Abnormal acidity of the blood, having increased hydrogen ions
and a low ph.
d) Acne: Inflammatory pile-sebaceous disease characterized by pus filled
cysts in the skin.
e) Actinomycosis: Fungal disease caused by actinomycetes.
f) Addison’s disease: Disease of deficient secretion from adrenal cortex.
g) Adenoma: A non-malignant tumour of glandular tissue.
h) Adolescence: Age between puberty and full maturity (youth).
2. i. Aerosol: Atomized particles suspended in gaseous form inhalation.
j. Agranulocytosis: Marked reduction of granulocytes in WBC.
k. Albuminuria: Presence of albumin in urine.
l. Alopecia: Baldness or falling off of hair from scalp.
m. Amenorrhea: Absence of menses during adults life in women.
n. Amnesia: Partial or complete loss of memory.
o. Anaphylaxis: Immediate and acute type of severe allergy often associated
with hypotension and shock.
p. Anemia: Symptom complex characterized by loss of appetite, restlessness,
breathlessness and loss of weight and is due to decreased oxygen carrying
capacity of blood, due to haemoglobin or RBC count.
q. Angina pectoris: Constricting type of chest pain, often radiating to left arm
due to diseased cardiac condition : cardiac ischemia.
3. r. Angioneurotic oedema: Severe form of allergy, involving face, hands,
genitals, or throat with sever oedema.
s. Anorexia: Loss of appetite.
t. Antisera: Supernatant fluid containing anti-bodies.
u. Anuria: Absence of secretion of urine by the kidney.
v. Anxiety: Feeling of apprehension, worry, uneasiness and mental tension.
w. Appendicitis: Inflammation of vermiform appendix.
x. Aplastic Anemia: Anemia with less number of RBC, as well as less WBC
and TC due to bone marrow depression.
y. Apnea: Transitory cessation of breathing.
z. Arrhythmia: Any deviation from the normal rhythm of heart beat.
aa. Arthritis: Inflammation of Joints.
4. 1. Asthma: Spasmodic chronic disease characterized by breathlessness;
cause by narrowing of the bronchial passages (spasm of bronchioles)
especially during exhalation.
2. Astringent: As agent which contracts organic tissue, thus lessening the
secretion and hardening of the surface.
3. Ataxia: Defective muscular control, resulting in irregular and jerky
movement.
4. Atherosclerosis: Hardening and narrowing of arteries.
5. Auricular fibrillation: Irregular and rapid atrial contraction of the heart.
6. Auricular flutter: Rapid and regular atrial rhythmic contractions of the
heart.
7. Azoospermia: Absence of spermatozoa in semen.
8. Bactericidal: Agent that kills bacteria and microbes (bacteria).
9. Bacteriostatic: Agent that prevents the multiplication of microbes .
5. 10. Beriberi: Disease of vitamin B1 deficiency.
11. Blood dyscrasias: A diseased state of blood.
12. Bradycardia: Slow rate of contraction of heart.
13. Breathlessness: Excessive conscious breathing.
14. Bronchitis: Inflammation of bronchi.
15. Carcinoma or cancer: A malignant tumour- dangerous, virulent spreading
growth, developing metastasis, resulting from chronic irritation.
16. Cataract: Development of opacity in lens of the eye.
17. Chemoreceptor trigger zone: Area located in the fourth ventricle ( area
postrema) of medulla oblongata responsible for initiating vomiting.
18. Chey-stroke’s breathing: Intermittent stopping of breathing.
19. Choriocarcinoma: Malignant tumour arising from chorion cells of the
embryo.
6. 20. Cirrhosis: Hardening of the organ. E.g. cirrhosis of liver.
21. Colic: Abnormal contraction of a hollow viscera. E.g. abdominal colic.
22. Colitis: Inflammation of colon.
23. Coma: A state of profound unconsciousness.
24. Conception: The act of becoming pregnant.
25. Congestive cardiac failure: Inadequate output of blood from one or both
ventricles of the heart, resulting in a failure of congestive type (CCF).
26. Congenital: Hereditary, existing from birth.
27. Conjunctivitis: Inflammation of conjunctiva.
28. Constipation: Formation of hard stools and/or delayed normal defecation.
29. Convulsions: Violent, spasmic and paroxysmal, contractions of voluntary
muscles.
7. 30. Cretinism: Thyroid deficiency disease present from the birth and
characterized by retarded physical and mental growth of children.
31. Cryptorchism: A development defect in man whereby the testes do not
descend into the scrotum.
32. Crystalluria: Appearance of crystals in urine.
33. Cushing’s syndrome: A disorder due to excessive adrenal cortical
hormone.
34. Cyanosis: Bluish tinge due to lack of oxygen in the blood.
35. Cycloplegia: Loss of accommodation of eye due to paralysis of ciliary
muscles of eye.
36. Dandruff: Infective inflammatory scaling disease of scalp, face and
sometimes other areas of body.
37. Delirium: Abnormal mental condition characterized by confusion,
hallucination and restlessness.
8. 38. Dermatitis: Inflammation of the skin.
39. Diabetic coma: Coma pertaining to diabetic condition of profound
unconsciousness.
40. Diabetic insipidus: Deficiency of vasopressin in posterior pituitary harmone
(anti-diuretic hormone component) leading to excessive urine production.
41. Diarrhea: Inflammation, swell or stretch out from within resulting in liquid
stools.
42. Diplopia: Double vision.
43. Dizziness: Giddiness.
44. Drug fever: Hypersensitive state leading to increase in body temperature
due to administration of a drug.
45. Dwarfism: Decreased linear growth of the body due to growth hormone
deficiency.
9. 46. Dysmenorrhea: Painful menstruation in women.
47. Dysphoria: Exaggerated feeling of depression and unrest.
48. Dyspepsia: Indigestion in stomach.
49. Dyspnea: Difficulty in breathing.
50. Dystrophy: Defective nutrition (muscular dystrophy – genetically determined,
primary degenerative myopathy).
51. Edema: Abnormal infiltration of tissue with fluid.
52. Embolism: Obstruction of blood vessel by thrombi, air or any other material,
away from the site organ.
53. Emesis: An act of vomiting.
54. Endocarditis: Inflammation of the inner lining (endocardium) of heart.
55. Endometritis: Increased eosinophil count in the WBC of blood.
10. 56. Epilepsy: Organic brain disorder, associated with attacks of convulsion and
unconsciousness.
57. Epistaxis: Bleeding from the nose.
58. Erythema: Redness of the skin (an allergic reaction).
59. Euphoria: An exaggerated feeling of well being, ecstasy.
60. Exophthalmos: Abnormal protrusion of eye balls.
61. Extrapyramidal: Akinesia, tremor and rigidity caused by deficiency or
dopamine in extrapyramidal tracts of the brain.
62. Extrasystole: Premature extra-beat of the heart.
63. Fibrillations: Repeated asynchronous contractions.
64. Gastric lavage: Washing out of the stomach through a rubber tube by
siphon action.
11. 65. Gastritis: Inflammation of gastric mucosa in stomach.
66. Gastroenteritis: Inflammation of the mucus membrane of the stomach and
intestine.
67. Gestation: Pregnancy.
68. Gigantism: Increased linear growth of the body due to excessive growth
hormone.
69. Glaucoma: Eye condition where the intraocular pressure is raised.
70. Glomerulonephritis: Inflammation of the glomeruli of the kidney.
71. Glossitis: Inflammation of tongue.
72. Goitur: Enlargement of thyroid gland.
73. Gout: A form of metabolic disorder in which sodium biurate is deposited in
the cartilages of joints and ear.
12. 74. Granulocytopenia: Abnormal reduction in number of granulocytes of WBC
in the blood.
75. Grave’s disease: Thyrotoxicosis, i.e. excessive formation of thyroid
hormone.
76. Gynecomastia: Enlargement of male mammary gland.
77. Hematemesis: Vomiting of blood.
78. Hematuria: Presence of blood in urine.
79. Hemoglobinemia: Decrease of haemoglobin in the blood plasma.
80. Hemoptysis: Counghing of blood.
81. Hemorrhage: Bleeding.
82. Heart block: Inhibition of speed of conduction of the impulse from auricle to
ventricle of the heart. It may be partial or complete.
13. 83. Heart-burn: Hyperacidity state with gastric contents coming into the mouth
and causing burning sensation in the chest.
84. Hemorrhoids: Swelling containing varicose (dilated) veins in the mucous
membrane of anus (piles)
85. Hepatitis: Inflammation of liver.
86. Hepatoxicity: Harmful effect in liver.
87. Hirsutism: Excessive growth of hair on the body.
88. Hodgkin’s disease: Progressive disease of RES showing enlargement of
lymphatic glands.
89. Hyperglycemia: Increase in blood sugar level.
90. Hyperkaliemia: Increase in potassium content above normal in the blood.
91. Hyperplasia: Excessive formation of cells or over growth in gingival region.
14. 92. Hypertension: High blood-pressure.
93. Hypersensitivity: Abnormal sensitivity to a stimulus of any kind.
94. Hyperthyroidism: Condition caused by excessive secretion of thyroid
hormone from thyroid glands.
95. Hyperuricemia: Abnormal amount of uric acid in blood.
96. Hypoglycemia: Decrease of blood sugar level.
97. Hypokalemia: Decrease in potassium content below normal level in the
body.
98. Hypotension: Low blood-pressure.
99. Hypothermia: Fall in the body temperature.
100. Hypoxia: Diminished amount of oxygen in the tissues.
15. 101. Impotence: Inability of the male to attain or sustain erection satisfactory for
normal coitus.
102. Infection: Disease transmissible from one person to another.
103. Inflammation: Tissue reaction to injury, infection or irritation characterized
by heat, redness, pain and swelling.
104. Insomnia: Chronic inability to sleep.
105. Iritis: Inflammation of iris.
106. Ischemia: Reduced blood supply.
107. Jaundice: A condition characterized by raised bilirubin level in the blood,
leading to yellowish skin and conjunctiva.
108. Kala-azar: An infection disease resulting in leishmaniasis.
109. Labor: Physiological process by which the fetus is expelled from the uterus
at term.
16. 110. Lacrimation: Outflow of tear.
111. Lactation: Breast feeding.
112. Laryngospasm: Spasm of laryngeal muscles.
113. Leukocytosis: Increase in total WBC count about 11,000/cmm.
114. Leucopenia: Decrease in total WBC count below 4,000/cmm.
115. Leukemia: Increase in leucocyte (total WBC) count above 50,000/cmm,
with immature cells from bone marrow.
116. Malignant growth: Rapidly growing, worsening with metastasis, cancer,
sarcoma.
117. Mania: A type of mental disease characterized by undue elation of mood
and psychomotor excitation, alternating with depression of mood.
118. Meningitis: Inflammation of the meninges of brain.
17. 119. Menopause: Permanent stoppage of menses, heralding old age women.
120. Myalgia: Muscle pain.
121. Myasthenia gravis: An autoimmune disease characterized by marked
weakness of voluntary muscles.
122. Mydriasis: Dilation of the pupil of the eye.
123. Myeloma: Multiple tumors in bones and their marrow.
124. Myositis: Inflammatory and degenerative changes in muscles.
125. Myotonia: Difficulty in relaxing the muscles after they have been
contracted.
126. Myxedema: Clinical condition of hypothyroidism in adults with decreases
in BMR.
127. Narcolepsy: Tendency to fall asleep.
18. 128. Narcosis: Unconsciousness produced by the drug.
129. Nausea: Vomiting sensation without, or prior to, vomiting.
130. Necrosis: Localized death of tissue.
131. Nephritis: Inflammation of the kidney.
132. Neurogenic: Originating in nerve cells.
133. Nystagmus: Involuntary and jerky movement of eye balls.
134. Obesity: Abnormal increase of fat in the body.
135. Oliguria: Decrease in production of urine.
136. Orthostatic: Caused by upright position (e.g. Orthostatic hypotension).
137. Osteoarthritis: Degenerative condition of large joint causing stiffness.
138. Osteoma: Tumour of bony tissue.
19. 139. Osteomalacia: Adult rickets (Disease of Vitamin – D deficiency.
140. Osteomyelitis: Inflammation of bone marrow or bone.
141. Osteoporosis: Loss of bone density due to excessive absorption of
calcium and phosphorous from the bone.
142. Palpitation: Rapid heart beat.
143. Paralysis: Complete or incomplete loss of nervous function of a part of the
body.
144. Parkinsonism: Condition of Parkinson’s and similar nervous disease;
blank face and tremors, movement of thumb, muscular rigidity, etc.
145. Paroxysmal tachycardia: Marked increase in frequency of heart beat of
temporary but sudden origin.
146. Peptic ulcer: Circumscribed ulceration of gastric mucosa.
147. Pericarditis: Inflammation of the covering membrane of the heart.
20. 148. Peritonitis: Inflammation of peripheral nerves.
149. Petit mal: Clouding of consciousness with no convulsions, type of epilepsy.
150. Pheochromocytoma: Tumor of adrenal medulla.
151. Photophobia: Abnormal sensitiveness of eyes to light.
152. Pleurisy: Inflammation of pleura.
153. Pneumonia: Acute infection and/or inflammation of the alveolar spaces of
lungs.
154. Poliomyelitis: Destruction of upper motor neurons causing flaccid
paralysis and washing of muscles.
155. Polyuria: Excretion of excessive amount of urine.
156. Pericardial: Pertaining to the area of chest immediately over the heart.
157. Prophylactic: Preventive.
21. 158. Puberty: The age at which reproductive organs become functionally active
(pre-youth state).
159. Raynaud’s syndrome: Spasm of the digital arteries, producing pallor or
cyanosis of fingers or toes.
160. Refractory period: Resistant period during a cardiac beat.
161. Rheumatism: The term referring to disease characterized by affection of
the smaller peripheral joints, accompanied by joint deformities and muscle
wasting.
162. Rickets: Disease of Vitamin D deficiency in children.
163. Scabies: Infectious parasitic disease of skin characterized by itching and
minute superficial burrows in the skin.
164. Scurvy: Disease of Vitamin C deficiency.
165. Schizophrenia: A group of mental illness characterized by disorganization
of the patient’s personality.
22. 166. Tachycardia: Excessive rapid rate of heartbeat.
167. Tachyphylaxis: Quickly developing tolerance, with decreasing drug effect.
168. Tetany: Condition of hyper-excitability in which, mild stimuli produces
cramps and spasms.
169. Thrombocytopenia: A reduction in the number of platelets (TC) in the
blood.
170. Thrombosis: Intravascular formation of blood clot.
171. Thyrotoxicosis: Condition due to excessive production of thyroid
hormone.
172. Tonsillitis: Inflammation of the tonsils in the throat by infection.
173. Trachoma: Contagious inflammation affecting conjunctiva, cornea and
eyelids.
174. Trauma: A wound or injury especially produced by external force.
23. 175. Tremor: Involuntary trembling of skeletal muscles.
176. Tumor: An abnormal mass of tissue, the growth of which is extreme and
uncoordinated and persists even after cessation of the stimulus which
evoked this change.
177. Ulcer: Local defect or an open sore, with pis, on or in the body.
178. Vaginitis: Inflammation of the vagina.
179. Vasoconstriction: Narrowing of the lumen of blood vessels.
180. Vasodilation: Widening of the lumen of blood vessels.
181. Vertigo: Giddiness
182. Virilism: Appearance of secondary male characterized in the female.
183. Xeropthalmia: Vitamin A deficiency disease of the eyes.