Pertussis is an infectious disease caused by the Bordetella pertussis bacterium, which was first isolated in 1906. The bacteria attaches to respiratory cilia and produces toxins that paralyze the cilia, causing inflammation of the respiratory tract and difficulty expelling pulmonary secretions. It is a highly contagious disease transmitted through coughing or sneezing within close contact, and has an incubation period of 7-10 days followed by three illness stages: catarrhal, paroxysmal cough, and convalescence.