Peripheral odontogenic fibroma is a rare benign tumor originating from odontogenic connective tissue, classified as an extraosseous lesion most commonly found in the jaw. It typically presents as a painless, well-circumscribed growth within the gingiva, with variations in size and consistency, characterized by specific histopathological features. Surgical excision is the recommended treatment, and recurrence is infrequent.

1. PERIPHERAL
ODONTOGENIC FIBROMA
Presentation by:
SWALIHA ALTHAF

2. Content
• INTRODUCTION
• CLASSIFICATION
• PERPHERAL ODONTOGENIC FIBROMA
• CLINICAL FEATURES
• RADIOLOGHIC FEATURES
• HISTOPATHOLOGY
• DIFFERENTIAL DIAGNOSIS
• TREATMENT

3. Odontogenic fibroma is a rare benign
neoplasm derived from connective
tissue of odontogenic origin and it can
be either a peripheral lesion or a
cental (intraosseous) lesion
ODONTOGENIC FIBROMA :
DEFINITION :

4. Odontogenic tumours
(classification)
A. Benign
I. Odontogenic epithelium :
• Ameloblastoma
• Squamous odontogenic tumour
• Calcifying epithelial odontogenic tumour
(pindborg tumour)
• Adenomatoid odontogenic tumour
• Keratocystic odontogenic tumour

5. II. Odontogenic epithelium with
odontogenic ectomesenchyme
• Ameloblastic fibroma
• Ameloblastic fibrodentinoma
• Ameloblastic fibro-odontoma
• Complex odontoma
• Compound odontoma
• Odontoameloblastoma
• Calcifying cystic odontogenic tumour
• Dentinogenic ghost cell tumour

6. III. Odontogenic ectomesenchyme :
• Odontogenic fibroma
• Myxoma (myxofibroma)
• Cementoblastoma (benign cementoblatoma,true
cementoma)
B.Malignant
I. Odontogenic carcinomas :
• Malignant ameloblastoma
• Ameloblastoma carcinoma
• Primary intraosseous carcinoma

7. • Clear cell odontogenic carcinoma
• Ghost cell odontogenic carcinoma
II. Odontogenic sarcomas :
• Ameloblastoma fibrosarcoma
• Ameloblastoma fibrodentinosarcoma
• Ameloblastoma fibro-odontosarcoma

8. • Peripheral odontogenic fibroma is the most
common form of the disease, which develpos
extraosseously from the tooth bearing areas of
the jaw
Defination :
Origin :
The lesion probably arises from the overlying
gingival epithelium or the cell rests of the
dental lamina

9. Clinical Features
• There was no gender predilection, while
the ages of the patients ranged from 5 to
65 years.
• Clinically appears as a show enlarging,
exophytic well-circumscribed ,sessile
growth of the gingiva.

10. Occurs in the mandible than the maxilla.
The lesion is usually firm in consistency it is painless and
the overlying epithelium is of normal colour.
Most of the lesion occur on the facial gingiva and their
size ranges between 0.5 to 1.5 centimeter in diameter

11. • More than one lesion can occur in the oral
cavity but rarely .
• There can be erythematous changes or even
ulcerations on the surface epithelium which
result from trauma.
• Consistency of the lesion varies,since lesions
may occur with ossification or without
ossification

12. Interdental lesions may
causes seperation of the
teeth

13. • Since peripheral odontogenic fibromas are small
lesions and they occur extraosseously within the
gingiva,radiographic changes in the bone are not
apparently found
• In certain saucerization of the cortical bone or
widening of the periodontal ligament space at the
cervical region may be seen
• Numerous foci of small radioopaque masses are
sometimes found within few lesions of peripheral
odontogenic fibroma,which indicate calcification
within indicate calcifcations within the tumor.
Radiographic Features :

14. Odontogenic fibroma producing a large irregular radiolucent
area containing numerous radiopaque foci

15. HISTOPATHOLOGY
• The peripheral odontogenic fibroma consists of a
markedly cellular fibrous connective tissue
parenchyma with scanty or numerous non-
neoplastic islands,strands and cords of columnar
or cuboidal,sometimes vacuolated odontogenic
epithelium.
• When numerous,the peripheral odontogenic
fibroma has been occasionally mistaken for an
epithelial neoplasma such as a peripheral
ameloblastoma

17. • This epithelium is usually deep in the
lesions,away from the surface epitheluim and is
the lesion,away from the surface epithelium and
is sometimes found ‘cuffing’ calcifications.
• Calcified tissue may or may not be present in the
peripheral odontogenic fibroma
• If found ,it may resemble trabeculae of bone or
osteoid,dentin or osteodentin (sometimes
described as dysplastic dentin ) or cementum
like material.

18. • Mature fibrous connective tissue stroma is
present and is sometimes highly
vascularized,particularly in the less cellular
areas.
• Myxomatous changes may also be found in the
stroma and the presence of inflammation is
variable.

20. Peripheral ossifying fibroma
Peripheral giant cell granuloma
True fibroma
Neurofibroma
Fibroepithelial polyp

21. • The lesion is treated by surgical excision
• Recurrence is not common.