Hold oxygen mask
Monitor vital signs
IV fluids if needed
45 8/31/2012 Dr. Nitika Jain
46 Dr. nitika jain 31 August 2012
Local anesthetic and analgesic
administration during pregnancy
Local anesthetics are safe to use during pregnancy.
Lignocaine is the local anesthetic of choice during
pregnancy.
Use the minimum effective dose.
Avoid repeated administration of local anesthetics.
Use aspirin or acetaminophen for analgesia during
pregnancy.
Avoid NSAIDs during pregnancy
Periodontitis is a complex infection initiated by bacteria –tissue destruction.
Host: the organism from which a parasite obtains its nourishment/ an individual who receives a graft
Modulation: the alteration of function or status of something in response to a stimulus or an altered physical or chemical environment
Certains medications have been associated with gingival enlargement.
the seminar gives a complete analysis of etilogy and pathogenesis involved in digo as well as sequlae of it
Periodontitis is a complex infection initiated by bacteria –tissue destruction.
Host: the organism from which a parasite obtains its nourishment/ an individual who receives a graft
Modulation: the alteration of function or status of something in response to a stimulus or an altered physical or chemical environment
Certains medications have been associated with gingival enlargement.
the seminar gives a complete analysis of etilogy and pathogenesis involved in digo as well as sequlae of it
PERIODONTAL THERAPY IN FEMALE PATIENTS Presented by- Dr. Himanshu gorawat Dr. Himanshu Gorawat
Throughout a human life cycle hormonal influences affect therapeutic decision making in periodontics. Historically therapies have been gender biased.
Oral health care professionals have greater awareness and capabilities of dealing with hormonal influences associated with reproductive process.
Periodontal and oral tissue responses may be altered, creating diagnostic and therapeutic dilemmas.
Therefore it is imperative that the clinician recognizes customize and appropriately alter periodontal therapy according to the individual woman’s needs based on the stage of her life cycle.
Definition of periodontal pocket, classification, Histopathology of periodontal pocket, microflora involved, pathogenesis, periodontal pocket as a healing lesion, microtopography of root surface, treatment of periodontal pocket
In periodontology, classifications are widely used to categorize defects due to periodontitis according to their etiology, diagnosis, treatment and prognosis.
Several classifications have been proposed in the literature in order to facilitate the diagnosis of gingival recessions.
This is a brief compilation of the how periodontal diseases come about. It explains the concept of the causative agent and all virulence factors used. it also outlines the host response to these irritating factors which has been known to be more responsible for the clinical outcome of periodontal diseases.
THIS PRESENTATION INCLUDES:
INTRODUCTION
MAIN BLOOD SUPPLY BRANCHES TO PERIODONTIUM
BLOOD SUPPLY TO MAXILLARY TEETH AND PERIODONTIUM
BLOOD SUPPLY TO MANDIBULAR TEETH AND PERIODONTIUM
VENOUS DRAINAGE OF MAXILLARY AND MANDIBULAR TEETH AND PERIODONTIUM
BLOOD SUPPLY TO EACH COMPONENT OF PERIODONTIUM
CLINICAL SIGNIFICANCE OF BLOOD SUPPLYING THE PERIODONTIUM
CLINICAL CORELATIONS WITH GINGIVITIS AND PERIODONTITIS
CONCLUSION
REFERENCES
Phase I periodontal therapy is the first in the chronologic sequence of procedures that constitute periodontal treatment. It is also referred to as cause related therapy or non-surgical periodontal therapy.
REFERENCES TAKEN FROM CARRANZA'S TEXTBOOK OF CLINICAL PERIODONTOLOGY AND LINDHE'S TEXTBOOK OF CLINICAL PERIODONTOLOGY AND IMPLANT DENTISTRY. CONTAINS ENOUGH AND MORE DETAILS OF THIS TOPIC FOR BDS STUDENTS.HOPE THIS PRESENTATION WILL HELP U GAIN SOME KNOWLEDGE ABOUT PERIODONTAL PLASTIC AND ESTHETIC DENTISTRY.
Furcation involvement is a common sequela of severe chronic periodontal disease. Its effective management has a profound influence on the outcome of periodontal therapy.
PERIODONTAL THERAPY IN FEMALE PATIENTS Presented by- Dr. Himanshu gorawat Dr. Himanshu Gorawat
Throughout a human life cycle hormonal influences affect therapeutic decision making in periodontics. Historically therapies have been gender biased.
Oral health care professionals have greater awareness and capabilities of dealing with hormonal influences associated with reproductive process.
Periodontal and oral tissue responses may be altered, creating diagnostic and therapeutic dilemmas.
Therefore it is imperative that the clinician recognizes customize and appropriately alter periodontal therapy according to the individual woman’s needs based on the stage of her life cycle.
Definition of periodontal pocket, classification, Histopathology of periodontal pocket, microflora involved, pathogenesis, periodontal pocket as a healing lesion, microtopography of root surface, treatment of periodontal pocket
In periodontology, classifications are widely used to categorize defects due to periodontitis according to their etiology, diagnosis, treatment and prognosis.
Several classifications have been proposed in the literature in order to facilitate the diagnosis of gingival recessions.
This is a brief compilation of the how periodontal diseases come about. It explains the concept of the causative agent and all virulence factors used. it also outlines the host response to these irritating factors which has been known to be more responsible for the clinical outcome of periodontal diseases.
THIS PRESENTATION INCLUDES:
INTRODUCTION
MAIN BLOOD SUPPLY BRANCHES TO PERIODONTIUM
BLOOD SUPPLY TO MAXILLARY TEETH AND PERIODONTIUM
BLOOD SUPPLY TO MANDIBULAR TEETH AND PERIODONTIUM
VENOUS DRAINAGE OF MAXILLARY AND MANDIBULAR TEETH AND PERIODONTIUM
BLOOD SUPPLY TO EACH COMPONENT OF PERIODONTIUM
CLINICAL SIGNIFICANCE OF BLOOD SUPPLYING THE PERIODONTIUM
CLINICAL CORELATIONS WITH GINGIVITIS AND PERIODONTITIS
CONCLUSION
REFERENCES
Phase I periodontal therapy is the first in the chronologic sequence of procedures that constitute periodontal treatment. It is also referred to as cause related therapy or non-surgical periodontal therapy.
REFERENCES TAKEN FROM CARRANZA'S TEXTBOOK OF CLINICAL PERIODONTOLOGY AND LINDHE'S TEXTBOOK OF CLINICAL PERIODONTOLOGY AND IMPLANT DENTISTRY. CONTAINS ENOUGH AND MORE DETAILS OF THIS TOPIC FOR BDS STUDENTS.HOPE THIS PRESENTATION WILL HELP U GAIN SOME KNOWLEDGE ABOUT PERIODONTAL PLASTIC AND ESTHETIC DENTISTRY.
Furcation involvement is a common sequela of severe chronic periodontal disease. Its effective management has a profound influence on the outcome of periodontal therapy.
An academic presentation on Dental considerations, interventions and precautions to ensure a safe pregnancy. The presentation deals with physiology, complications and dental considerations for treating a pregnant patient.
A benign tumor of muscular and fibrous tissues, typically developing in the wall of the uterus.
Prevalence varies among studies and countries (4.5-68.6%)
Nearly 20-30% Indian women in reproductive age group have fibroid uterus
At any given time, nearly 15-25 million Indian women have fibroid uterus
Understand fibroids in a better way
ENDOMETRIOSIS UPDATEFocus on Dienogest Dr Sharda jain dr Jyoti Agarwal Lifecare Centre
ENDOMETRIOSIS UPDATEFocus on Dienogest
AGENDA
Background
What’s New in Endometriosis
Clinical Discussions in Managing Endometriosis
Newer Evidences on Dienogest
Role of progestogens in obstetrics and gynecologyAhmad Saber
The
different progestogens with their overlapping effects on estrogen, androgen, glucocorticoid,
and mineralocorticoid receptors are described in order to allow the clinician to make the most appropriate choice of progestogen.
Uterine Fibroids: Symptoms, Causes, Risk Factors & Treatment uterine fibroids aren't associated with an increased risk of uterine cancer and almost never develop into cancer
Role of Dydrogesterone in Threatened Abortion Dr Sharda Jain Lifecare Centre
*EXPERINCE SHARING By EXPERTS*
Dr Uma Rai(DGF *E*)
Dr Sangeetaa Gupta(DGF *E*)
Dr Neerja Varshney(DGF *E*)
Dr Surjeet Kapoor(DGF *E*)
Dr Rupam arora(DGF *E*)
Dr Meenakshi Ahuja(DGF *S* )
Dr.Harsha khullar(DGF *C* )
Dr Mamta mittal(DGF *N*)
Dr Leena Sreedhar(DGF *D*)
Dr.Dipti Nabh(DGF *E*)
Dr. Shama Batra(DGF *E*)
Dr Poonam Paul(DGF *SW*)
PAN DGF ( DELHI GYNAECOLOGIST FORUM) CME ON DYDROGESTERONE ON 3/2 /22
Menopause role of isoflavones by dr alka mukherjee nagpur m.s.indiaalka mukherjee
Soy-based isoflavones are modestly effective in relieving menopausal symptoms; supplements providing higher proportions of genistein or increased in S(-)-equol may provide more benefits. Soy food consumption is associated with lower risk of breast and endometrial cancer in observational studies. The efficacy of isoflavones on bone has not been proven, and the clinical picture of whether soy has cardiovascular benefits is still evolving. Preliminary findings on cognitive benefit from isoflavone therapy support a "critical window" hypothesis wherein younger postmenopausal women derive more than older women
Several areas for further research have been identified on soy and midlife women. More clinical studies are needed that compare outcomes among women whose intestinal bacteria have the ability to convert daidzein to equol (equol producers) with those that lack that ability (equol nonproducers) in order to determine if equol producers derive greater benefits from soy supplementation. Larger studies are needed in younger postmenopausal women, and more research is needed to understand the modes of use of soy isoflavone supplements in women. The interrelations of other dietary components on soy isoflavones consumed as a part of diet or by supplement on equol production also require further study, as do potential interactions with prescription and over-the-counter medications. And finally, greater standardization and documentation of clinical trial data of soy are needed.
Soy products can take several weeks or more to reach their maximal benefit. For example, a 2015 review found that soy isoflavones take more than 13 weeks to reach just half of their maximum effect. Traditional hormone therapy, on the other hand, takes about three weeks to show the same benefit.
It’s packed with nutrition
Soy is low in saturated fat and calories. It’s also high in these beneficial nutrients:
• fiber
• protein
• omega-3 fatty acids
• antioxidants
It may help to reduce your risk of heart disease
Eating tofu and other soy-based foods a few times a week can help you cut back on some animal-based protein sources, such as steak or hamburger, that are high in saturated fat and cholesterol.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
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micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
3. Contents
Hormone and types of hormones
Female hormonal system
Conditions – clinical features and
management.
Puberty
Menstrual cycle
Pregnancy
Local anesthetic and analgesic
administration during pregnancy
3 Dr. Nitika Jain 8/31/2012
Antibiotic administration during
4. Periodontal disease and Preterm low
birth weight births
Association of periodontal disease and
pre eclampsia
Oral contraceptives
Menopause
Osteoporosis
Hormone replacement therapy
Conclusion
References
4 Dr. Nitika Jain 8/31/2012
5. Hormones are specific regulatory molecules that
modulate reproduction, growth and development,
maintenance of the internal environment, as well
as energy production, utilization, and storage
(Mariotti 1994). Hormonal effects reflect
physiological/ pathological changes
Steroids
in almost all types of tissues of the body
Glycoprotein
Polypeptides
Amines
5 Dr. nitika jain 31 August 2012
6. FEMALE
HORMONAL SYSTEM
6 Dr. nitika jain 31 August 2012
7. The female hormonal system, consists of
three hierarchies of hormones, as follows:
1. A hypothalamic releasing hormone, Gonadotropin-
releasing hormone (GnRH)
2. The anterior pituitary sex hormones, follicle-
stimulating hormone (FSH) and luteinizing hormone
(LH), both of which are secreted in response to the
release of GnRH from the hypothalamus
3. The ovarian hormones, estrogen and
progesterone, which are secreted by the ovaries in
response to the two female sex hormones from the
anterior pituitary gland.
7 Dr. nitika jain 31 August 2012
8. Ovarian hormones
Estrogen
Progesterone
8 Dr. nitika jain 31 August 2012
9. Age
Puberty
Menstrual cycle
Pregnancy
Menopause
9 Dr. nitika jain 31 August 2012
11. Pubertal changes
It is the transitional phase when a sexually
immature girl or boy becomes sexually
mature.
It lasts for 36 months.
Ovarian cycle – ovulation
Accessory sex organs grow
Bone and muscle growth takes place
Hormones FSH, LH sex steroid secretion - all
increase
11 Dr. nitika jain 31 August 2012
12. Effects on Periodontium
Enhanced blood circulation in the end
terminal capillary loops and associated
increased prevalence of
gingivitis/bleeding tendency
(Muhlemann 1948, Massler et al. 1950,
Curilovic et al. 1958, Sutcliffe 1972,
Daniell 1983)
Higher bacterial counts (especially
Prevotella intermedia (Pi) and
12
Capnocytophaga species)(Kornman &
Dr. Nitika Jain 8/31/2012
Loesche 1982, Mombelli et al. 1990,
14. Management
Preventive care
Milder gingivitis case scaling
and root planing with frequent oral
hygiene instructions.
Severe gingivitis case microbial
culturing, antimicrobial mouth
washes and local site delivery, or
antibiotic therapy.
14 Supportive periodontal therapy
Dr. Nitika Jain 8/31/2012
16. Pre menstrual
syndrome
Menstrual
cycle
16 Dr. Nitika Jain 8/31/2012
17. Pre menstrual syndrome ( PMS)
During the peak level of progesterone (about 7 – 10 days prior to
menstruation) PMS also occur.
No significant differences in estrogen and progesterone levels
between women who suffer PMS and women who do not.
Depression, irritability, mood swings, and difficulty with memory
and concentration due to reduced neuro transmitters
PMS women have lower of certain neuro transmitters such as
Enkaphalins
Endorphins
¥ amino butyric acid(GABA)
Serotonin
17 Dr. Nitika Jain 8/31/2012
18. Management of PMS
PMS is often treated by antidepressants. Selective
serotonin reuptake inhibitors are generally the first
line choice of drugs.
Increase the extracellular level of the
neurotransmitter serotonin by inhibiting its reuptake
into the presynaptic cell, increasing the level of
serotonin in the synaptic cleft available to bind to
the postsynaptic receptor. E.g. Fluoxetine,
Sertraline, Fluvoxamine, paroxetine, and
citalopram.
Other antidepressants are selective serotonin,
norepinephrine reuptake inhibitors( SNRI’s)
{increase the levels of two neurotransmitters in the brain
that are known to play an important part in mood,
serotonin, and norepinephrine.}, tricyclics, trazodone,
18
mirtazapine, nefazodone, maprotilline.
Dr. Nitika Jain 8/31/2012
19. Menstrual cycle
Recurs at the interval of 28 days.
4 phases:
Menstruation – bleeding phase ; 1 – 4 days
Proliferative phase – follicular phase ; 5 – 13 days
Phase of ovulation – 14th day
Secretive phase – luteal phase ; 14 – 28 days
19 Dr. nitika jain 31 August 2012
21. Two different clinical findings have been observed
in the oral cavity:
Gingival bleeding and
Increased production of gingival exudate
• Kribbs & Chesnut1984, Kribbs et al. 1989, Kribbs
1990,1992, Grodstein et al. 1996a, b).
Ulcerations of the oral mucosa and vesicular lesions
have also been noted in the luteal phase of the
menstrual cycle, although the incidence is low.
(Segal et al. 1974, Ferguson et al. 1978, 1984).
21 Dr. Nitika Jain 8/31/2012
22. Tumor necrosis factor α fluctuates during the
menstrual cycle, PGE2 elevated, angiogenetic
factors , endothelial growth factors, and receptors
may be modulated by Progesterone and estrogen
, contributing to increases in gingival inflammation
during certain stages of the menstrual cycle.
22 Dr. nitika jain 31 August 2012
24. Management
Women who have increased gingival bleeding
associated with the menstrual cycle SPT for
continuous 3 – 4 months is must.
Antimicrobial mouth rinses prior to cyclic inflammation
is indicated.
The dentist should treat the gingival and oral mucosal
tissues gently. Gauze pads or cotton rolls should be
moistened with a lubricant, chlorhexidine rinse, or
water before placing them in the aphtha-prone
patient.
Careful retraction of the oral mucosa, cheeks, and lips
is necessary in patients prone to aphthous or herpetic
lesions.
Because the hypoglycemic threshold is elevated, the
clinician should advise the patient to have a light
24 Dr. Nitika Jain before her appointment.
snack 8/31/2012
26. One Tooth Is Lost With Every pregnancy
Myth……..
But Women Do Experience
Some Changes in General and
Oral Health During Pregnancy,
Primarily Due to
Hormonal Level Changes
So They Characterize a Special
Group for Whom Extra care and
Special Care Need to Be Provided
26 Dr. Nitika Jain 8/31/2012
28. Stages of Pregnancy
1st Trimester (1-12 weeks)
Fetal organ formation and
differentiation.
Most susceptible to adverse
effects of teratogens.
Avoid all elective care but
provide care as needed.
8/31/2012 Dr. Nitika Jain 28
29. Stages of Pregnancy
2nd Trimester (13-24 weeks)
Fetal growth and maturation.
Safest period to provide dental
care.
8/31/2012 Dr. Nitika Jain 29
30. Stages of Pregnancy
3rd Trimester (25-40 weeks)
Fetal growth continues.
8/31/2012 Dr. Nitika Jain 30
31. Increased tendency for gingivitis and larger gingival
probing depths (Loe & Silness 1963,Silness & Loe
1964, Miyazaki et al. 1991, Robinson & Amar 1992,
Machuca et al. 1999, Soory 2000) and periodontitis
(Robinson & Amar 1992)
Increased susceptibility to infection (Cohen et al.
1969, Brabin 1985)
Decreased neutrophil chemotaxis and depressed
antibody production (Sooriyamoorthy & Gower 1989b,
Raber-Durlacher et al. 1991, Raber-Durlacher et al.
1993)
Increased numbers of periodontopathogens
(especially Porphyromonas gingivalis and Pi)
(Kornman & Loesche 1980, Tsai & Chen 1995)
Increased synthesis of PGE2 (ElAttar 1976)
31 Dr. Nitika Jain 8/31/2012
32. Tumor like enlargement/Pyogenic
granuloma
Incidence : 0.2 – 9.6 %
Pregnancy tumor or pregnancy epulis is
different from pyogenic granuloma which
occur in non pregnant females
2nd or 3rd trimester
Clinical features : Tumor like growth
appear on inter dental papilla of maxillary
anterior teeth
Grow rapidly, bleed easily, and become
hyperplastic, and nodular
Sessile or pedunculated or may be
ulcerated
32 Dr. nitika jain Color – purplish red to deep blue.
31 August 2012
34. Marginal gingival enlargement/
pregnancy gingivitis
Extremely common
Incidence: 30 – 75 %
Clinical features: Erythema ,
edema, hyperplasia, increased
bleeding.
Mild inflammation, pain ,
bleeding
Alteration in
immunocompetency during
pregnancy may create an
exaggerated response on
Periodontium.
Mainly anterior region and inter
proximal surfaces
Dr. nitika jain 31 August 2012
34 Anterior site inflammation may
be exacerbated by increased
35. Other oral manifestations of
pregnancy
Perimylolysis or acid production of teeth may
occur due to excessive morning sickness or
esophageal reflux
Xerostomia – 44% reported dryness ( El- Ashiry
G. comparative study of the pregnancy and oral
contraceptives on the gingiva. Oral Surg 1970.)
35 Dr. nitika jain 31 August 2012
37. Clinical management
Plaque control oral hygiene techniques must be taught,
reinforced, and monitored throughout the pregnancy.
Scaling and root planing must be performed when ever
necessary.
Avoid the use of high alcohol content antimicrobial rinses
in pregnant and prefer to use non – alcohol based oral
rinse.
Prenatal fluoride a controversial and inconclusive.
Studies by Glenn FB(1977, 1982) claimed the benefits
whereas studies by reported by (Reference manual. Pediarr
dent 1994) showed no clinical efficacy of prenatal fluoride.
ADA does not recommend the use of prenatal fluoride.
“prenatal F administration may reduce the incidence of
caries in the offspring”
Cox & Okerse.
37 Dr. Nitika Jain 8/31/2012
38. Treatment for Acid Exposure
Do NOT brush immediately after vomiting
Rinse
Water with baking soda
Antacid
Plain water
Eat some cheese
38 Dr. Nitika Jain 8/31/2012
39. Elective dental treatment
Prolonged chair time should be avoided
because the woman is most
uncomfortable at this time.
Supine hypotensive syndrome may
occur. In a semi reclined or supine
position , the great vessels particularly
inferior vena cava are compressed by
the gravid uterus. and this compression
will cause maternal hypotension,
39
decreased cardiac output, and eventual
Dr. Nitika Jain 8/31/2012
loss of consciousness.
40. How should the pregnant woman be
positioned?
Flat position may
cause hypotension and
hypoxia
Place a small pillow
under right hip - left
lateral displacement
Head above feet
40 Dr. Nitika Jain 8/31/2012
41. SUPINE HYPOTENSION
SYNDROME (Vena Cava Compression)
SUPINE POSITION AFTER 5TH MONTH
UTERUS COMPRESSES THE INFERIOR
VENA CAVA
↑VOL. BLOOD
↓RETURN TO THE HEART
REDUCED PERFUSION OF UTERUS
FETAL HYPOXIA
41 Dr. Nitika Jain 8/31/2012
42. Supine Hypotension Syndrome
Obstruction of inferior vena cava and aorta from
pressure of the large fetus.
Symptoms:
Sweating
Nausea
Weakness
Sense of lack of air
42 Dr. Nitika Jain 8/31/2012
43. Supine Hypotension Syndrome
Other symptoms:
Drop in blood pressure
Bradycardia
Possible loss of consciousness
43 Dr. Nitika Jain 8/31/2012
44. Prevention of Supine Hypotensive
Syndrome
Elevate right hip 10-12 cm.
Weight is taken off the major
vessels
8/31/2012 Dr. Nitika Jain 44
45. Treatment of Supine Hypotensive
Syndrome
Roll patient onto her
left side.
8/31/2012 Dr. Nitika Jain 45
46. Use of Radiation on Pregnant Patient
Dose given and time of gestation are important
doses < 5-10 rads (Gy) not teratogenic
fetus is most susceptible to radiation between the 2nd
and 6th week of gestation
single dental x-ray exposes patient to 0.01 millirads of
radiation. In relative terms, this amount is 40 times less
than daily dose acquired from cosmic radiation.
Therefore, diagnostic radiation should not be withheld
during pregnancy
46 Dr. Nitika Jain 8/31/2012
47. Radiographs during Pregnancy
Take as needed with optimal methods for reducing
secondary radiation and exposure time.
Always use a lead apron.
Exposure to fetus (with apron use) is .00001
centiGray.(rad)
Daily cosmic radiation - .0004 centiGray (rad)
47 Dr. Nitika Jain 8/31/2012
48. Risks of Dental X-Rays
X-ray only if necessary (i.e. root canal therapy,
trauma)
When x-rays are indicated, radiation exposure is
extremely low
Exposure can be limited by:
Lead apron shielding
Modern fast film
Avoiding retakes
48 Dr. Nitika Jain 8/31/2012
50. FDA drug classification for pregnancy
Combines risk statements including congenital
anomalies, fetal effects, perinatal risks, and
therapeutic risk-benefit ratio
Untreated disease or condition may pose more
serious risks to both mother and fetus than any
theoretical risks from the medication
Category A thru D and X
50 Dr. Nitika Jain 8/31/2012
51. Local anesthetic and analgesic
administration during pregnancy
51 Dr. Nitika Jain 8/31/2012
56. Periodontal
disease and Preterm
low birth weight
births
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56
57. WHO defination
Preterm birth as any live birth at less than 37
weeks of gestation.
Delivery at less than 32 weeks is termed as very
preterm
Delivery at less than 28 weeks is termed as
extremely preterm
Birth weight to be considered low if < 2500g, very
low if < 1500g and extremely low if <1000g.
57 Dr. Nitika Jain 8/31/2012
58. Health consequences of preterm
birth
Short term Long term
consequences consequences
Respiratory distress Cerebral palsy
syndrome Retinopathy of
Intraventricular prematurity
hemorrhage Mental retardation
Sepsis Cardiovascular
Patent ductus malformations
arteriosus
58 Dr. Nitika Jain 8/31/2012
59. Risk factor An exposure that
increases the probability that disease will
occur
Risk indicator A suspected risk factor
that is correctly identified through cross-
sectional study designs but there are not
yet longitudinal study data
60. Primary and secondary predictors of
pre term delivery
Primary predictors:
Black race
Young mother
Domestic violence
Low socio economic status
Stress or depression
Cigarette smoking
Cocaine or heroin use
Low body mass index
Low maternal weight gain before pregnancy
Previous induced abortion
Chronic lung disease
Chronic hypertension
Diabetes
Renal diseases
60 Dr. Nitika Jain 8/31/2012
61. Secondary predictors
No or adequate prenatal care
In vitro fertilization
Iron deficiency anaemia
Pre eclampsia
Early contractions
Placental abruptions
Multiple fetuses
61 Dr. Nitika Jain 8/31/2012
62. Offenbacher et al were the first to report a link
between poor maternal periodontal health and
adverse pregnancy outcomes.
The biological mechanism linking periodontal
infection and preterm birth can begin with
endotoxins resulting from gram-negative bacterial
infections, which stimulate the production of
cytokines and prostaglandins. It is known that
prostaglandins and certain cytokines (interleukin-
1b, interleukin-6 and tumor neucrosis factor-alfa),
in sufficient quantities, may stimulate labour
(Jeffcoat et al., 2001).
62 Dr. Nitika Jain 8/31/2012
64. According to Collins et al 1994, periodontitis serve as
a reservoir of gram negative organisms, LPS,
endotoxins and inflammation mediators TNF α which
are potential threat to fetal placental unit.
Local increase of PGE2 and TNF α in chamber fluid
with P.Gingivalis and 15 – 18 % of fetal weight.
levels of PGE 2 and TNF α is inversely proportional to
fetal birth weight.
Previous sensitization or exposure to these
pathogens prior to pregnancy enhanced the severity
of the fetal growth restriction when a secondary
exposure occurred.
64 Dr. Nitika Jain 8/31/2012
65. GCF levels of fluid levels of PGE2 were positively
associated with intra amniotic PGE2 levels,
suggesting that gram negative periodontal
infection may present systemic challenge
sufficient to initiate the onset of premature labor
as a source of LPS or through stimulation of
secondary inflammatory mediators such as PGE2
and interleukin 1.
Four organism associated with PLBW:
Bacteroides forsythus
Porphymonas gingivalis
Actinobacillus actinmycetemcomitans
Treponema denticola
65 Dr. Nitika Jain 8/31/2012
66. Various studies
Jeffcoat et al. (2001) studied 1,313 pregnant
women and the relationship between periodontal
disease and preterm birth, adjusting for a range
of risk factors including smoking, parity, race and
maternal age. The study found that pre-existing
periodontal disease in the second trimester of
pregnancy increased the risk of preterm birth.
Mitchell-Lewis et al (2001) cohort study
examined 21women for periodontal status. The
findings suggest that women who received basic
periodontal therapy during pregnancy were at a
substantially reduced risk of preterm, low
66 Dr. Nitika Jain 8/31/2012
birthweight babies
67. (Lopez et al., 2002) investigated whether the
women who had gingivitis and received treatment
before birth (n=406) reduced the risk of preterm
lowweight children comparing to women who had
periodontal (n=233) disease and were treated
after delivery. The study concluded that
periodontal disease is an independent risk factor
for preterm birth and low birth weight.
67 Dr. Nitika Jain 8/31/2012
68. Association of periodontal disease
and pre eclampsia
Pre – eclampsia is a common hypertensive
disorder of pregnancy that independently
contributes to maternal and infant morbidity and
mortality.
multi system disorder.
5-10% of all pregnancies.
Atherosclerotic changes in placental tissues
involving oxidative and inflammatory events
initiate the development of pre – eclampsia(
Ramos et al 1995)
68 Dr. Nitika Jain 8/31/2012
70. Triad of physiological derangement in
pre eclampsia:
Intense vasospasm
All these
factors leads to
intrauterine
fetal growth Disseminated
intravascular
retardation
coagulation
and fetal death
in uterus only.
Plasma volume
contraction
70 Dr. Nitika Jain 8/31/2012
71. Oral
Contraceptives
71 Dr. Nitika Jain 8/31/2012
72. Combined oral contraceptive pills were developed
to prevent ovulation by suppressing the release of
gonadotropins. Combined hormonal
contraceptives, including COCPs, inhibit follicular
development and prevent ovulation as their
primary mechanism of action
72 Dr. Nitika Jain 8/31/2012
73. Different formulations of hormonal
contraceptives
Combined oral contraceptive containing artificial
analogues of estrogen and progesterone
Low doses of estrogen and progesterone
(50µg/day) and /or progestins (1.5mg/day)
Progesterone based mini pill.
Slow release progesterone implants placed sub
dermally (NORPLANT)
DEPO PROVERA , a very effective progestin
injection
73 Dr. Nitika Jain 8/31/2012
74. Oral manifestations:
Inflammation ranges from mild edema and
erythema to severe inflammation with
hyperplastic gingival tissues.
Increased exudate in inflammed gingival tissues
of OC users.
Kalkwarf reported the response may be due to
alterations of the microvasculature, increased
gingival permeability, and increasing synthesis of
Prostaglandin.
PGE2 increases with increasing sex hormones
16 fold increase in bacteroides species ( because
74 increased sex hormones substituting for the 8/31/2012
Dr. Nitika Jain
75. Oral contraceptives
Treatment for gingival inflammation exaggerated
by oral contraceptives should include establishing
an oral hygiene program and eliminating local
predisposing factors.
Periodontal surgery may be indicated if there is
inadequate resolution after initial therapy.
Antimicrobial mouthwashes may be indicated as
part of the home care regimen.
Extraction of teeth to be performed on non –
estrogenic days( days 23 to 28) of the pill cycle,
to reduce the risk of postoperative localized
75
osteitis.
Dr. Nitika Jain 8/31/2012
77. Menopause
As women approach menopause, the levels of
estrogen begin to drop mainly during the late
follicular and lacteal phase of the menstrual cycle
(Sherman & Korenman 1975).
The time frame between regular cycles and the
cessation of menstrual periods, called
perimenopausal transition, is 2–7 years (Treloar
et al. 1970). During this period, the concentration
of circulating estrogen decreases while follicle-
stimulating hormone (FSH) and luteinizing
hormone (LH) concentrations increase (Monroe &
Menon 1977).
77 Dr. nitika jain 31 August 2012
78. Menopause
No ovulation
No menstrual cycle
No estrogen and progesterone is formed by the ovary
Changes due to menopause occur in
Sex organs – no ovulation
Bone- osteoporosis
Endocrinal – FSH and LH levels become high
Metabolic – lipid profile alters and more susceptible to
atherosclerosis
Cardiovascular – hot flushes can appear and
hypertension is common
Psychological states - depression
78 Dr. nitika jain 31 August 2012
79. Clinical changes in the periodontal
tissues during menopause and post
menopause
Reduction in epithelial keratinisation so thinning
of the oral mucosa.
A reduction in salivary gland flow
Drying of the oral tissues ( burning mouth)
Redness and abnormal paleness of the gingival
tissues
Bleeding on probing and brushing
Gingival recession
Altered taste sensation
Alveolar bone loss
Alveolar ridge resorption
79 Dr. Nitika Jain 8/31/2012
80. Menopause
As gingival and mucosal tissue thinning occurs,
so brushing with extra soft tooth brush.
Dentifrices with minimal abrasive particles should
be used.
Rinses should have low alcohol concentration.
80 Dr. Nitika Jain 8/31/2012
81. Osteoporosis
Osteoporosis is a disease of bones that leads to
an increased risk of fracture.In osteoporosis the
bone mineral density (BMD) is reduced, bone
microarchitecture deteriorates, and the amount
and variety of proteins in bone is altered.
Osteoporosis is defined by the World Health
Organization (WHO) as a bone mineral density
that is 2.5 standard deviations or more below the
mean peak bone mass (average of young,
healthy adults) as measured; the term
"established osteoporosis" includes the presence
of a fragility fracture
81 Dr. Nitika Jain 8/31/2012
82. The disease may be classified as
primary type 1,
primary type 2, or secondary.
The form of osteoporosis most common in
women after menopause is referred to as primary
type 1 or postmenopausal osteoporosis.
Primary type 2 osteoporosis or senile
osteoporosis occurs after age 75 and is seen in
both females and males at a ratio of 2:1
82 Dr. Nitika Jain 8/31/2012
83. Effect of osteoporosis upon
Periodontium
Poor wound healing: less attachment formation
(von Wowern et al. 1994)
Reduced bone mineral content in the jaws (von
Wowern et al. 1994, Payne et al. 1999)
Increase of periodontosis and tooth loss
(Mittermayer et al. 1998)
83 Dr. nitika jain 31 August 2012
84. Bone metabolism
The estrogen deficiency leads to
(1) increased osteoclastic activity in the bones,
(2) decreased bone matrix, and
(3)decreased deposition of bone calcium and
phosphate
84 Dr. nitika jain 31 August 2012
85. Normal bone Osteoporotic bone
85 Dr. Nitika Jain 8/31/2012
86. Prevention of osteoporosis
Education
Calcium and milk
Avoid smoking
Exercise
Appropriate drug treatment
86 Dr. Nitika Jain 8/31/2012
87. Treatment
Bisphosphonate drugs are the first-line treatment in
women
sodium alendronate (Fosamax) 10 mg a day or 70 mg
once a week,
risedronate (Actonel) 5 mg a day or 35 mg once a week
and/or
ibandronate (Boniva) once a month.
Estrogen replacement therapy remains a good
treatment for prevention of osteoporosis.
Calcitonin works by directly inhibiting osteoclast
activity via the calcitonin receptor. Calcitonin
receptors have been identified on the surface of
osteoclasts. Calcitonin directly induces inhibition of
Dr. Nitika Jain
87 8/31/2012
osteoclastic bone resorption by affecting actin
88. National institutes of health consensus
conference recommendations for optimal
calcium intake
Pre menopausal women(25 – 50 yrs)
1000mg/day
Post menopausal women(estrogen therapy)
1000mg/day
Post menopausal women(no estrogen therapy)
1500mg/day
Men
1000mg/day
Women and men > 65 years old
88 1500mg/day
Dr. Nitika Jain 8/31/2012
89. Hormone replacement therapy
It is based on the idea that the treatment may
prevent discomfort caused by diminished
circulating oestrogen and progesterone
hormones, or in the case of the surgically or
prematurely menopausal, that it may prolong life
and may reduce incidence of dementia. It
involves the use of one or more of a group of
medications designed to artificially boost
hormone levels. The main types of hormones
involved are oestrogens, progesterone or
progestins, and sometimes testosterone.
89 Dr. Nitika Jain 8/31/2012
90. CONVENTIONAL HORMONE REPLACEMENT
DRUGS
The most frequently prescribed estrogen product for
HRT is conjugated equine estrogens (brand name
Premarin). The most frequently prescribed progestin for
HRT is medroxyprogesterone acetate (MPA).
BIO-IDENTICAL HORMONES COMPOUNDED
There are many alternatives to conventional drug
products, including natural or bio-identical hormones,
which are identical in chemical structure to the
hormones naturally produced by our bodies. This type of
HRT is referred to as natural hormone replacement
therapy, or NHRT.
NHRT is available both in brand-name products and
from compounding pharmacies, which can supply any of
the bio-identical hormones alone or combine them into
one dose in the form desired (e.g, sublingual tablets, oil
Dr. Nitika Jain
90 caps, or cream). 8/31/2012
91. Dosages prescribed for ERT, HRT and NHRT
vary and can be adjusted to meet a woman’s
specific needs.
Relatively low doses of estrogen and
estrogen/progestin is effective for treating
symptoms of menopause and can also maintain
bone density.
Low doses of estrogen, doses of conjugated
equine estrogen (Premarin) as low as .3 mg
(compared to the "standard" dose of .625 mg)
alone or combined with a reduced dose of
progestin; doses of oral estradiol as low as .25
mg; and a transdermal patch dose of .025
91 micrograms. Using lower doses of estrogens8/31/2012
Dr. Nitika Jain
and
92. Conclusion
Female patients may present with periodontal
and systemic considerations that alter
conventional therapy.
Patients should be educated regarding the
profound effects of the sex hormone on
periodontal and oral tissues as well as the
consistent need for home and office removal of
local irritants.
Thorough medical history in the female patient
should include questions regarding menstrual
regularity, oral contraceptive use , hormone
replacement therapy, fertility medications,
Dr. Nitika Jain
92 8/31/2012
pregnancy, breast feeding.
94. Clinical periodontology, Carranza 10th edition.
Periodontal medicine. Rose, Genco, Mealey ,
Cohen.
Mascarenhas P, Gapski R, Al-Shammari K, Wang
H-L: Influence of sex hormones on the
Periodontium. J Clin Periodontol 2003; 30: 671–
681. rBlackwell Munksgaard, 2003.
GN güncü, TF tözüm, F ça˘glayan: effects of
endogenous sex hormones on the periodontium –
review of literature. Australian dental journal
2005;50:(3):138-145.
94 Dr. nitika jain 31 August 2012
95. Concise medical physiology 5th edition, chaudhari
Despopoulos, color atlas of physiology 5th
edition.
Text book of medical physiology, 11th edition.
Guyton and hall.
MARJORIE K et al. Post-menopausal bone loss
and its relationship to oral bone loss.
Periodontology 2000, Vol. 23, 2000, 94–102.
95 Dr. nitika jain 31 August 2012