This document summarizes the development of new bio-based packaging materials from the lab scale to pilot production. Researchers produced multilayer structures using materials like bio-PBSA, PLA-X, fibrillated cellulose, and paper through extrusion coating and dispersion coating. Barrier properties were characterized, and pilot lines were used to produce demo packages for testing. While scaling up presented challenges that impacted material performance, the results demonstrate the viability of producing these novel bio-based packaging solutions at a larger scale. Further optimization is still needed to improve barrier properties and reduce costs.