Brain tumours are responsible for approximately
2% of all cancer deaths. Central nervous system
tumours comprise the most common group of
solid tumours in young patients, accounting for
20% of all paediatric neoplasms. The overall incidence
of brain tumours is 8–10 per 100 000 population
per year. A study by the United States
Department of Health in 1966 showed the incidence
to be 21 per 100 000 per year at 2 years old
and 1 per 100 000 during the teenage years. The
incidence increases after the 4th decade of life to
reach a maximum of 16 per 100 000 per year in the
7th decade. There has been an intense debate concerning
the increased incidence of brain tumours,
especially in the elderly, but this possible increase
could be explained due to the advent of CT and
MRI leading to better detection of tumours.
Classification
The general brain tumour classification is related
to the cell of origin, and is shown in Table 6.1.
Table 6.2 shows the approximate distribution
of the more common brain tumours.
This chapter will discuss the tumours derived
from the neuroectoderm and metastatic tumours.
The following chapters will describe the benign
brain tumours and pituitary tumours.
Aetiology
Epidemiology studies have not indicated any
particular factor (viral, chemical or traumatic)
that causes brain tumours in humans, although a
range of cerebral tumours can be induced in animals
experimentally. There is no genetic predis
T1-weighted images optimally show normal soft-tissue anatomy and fat (e.g. to confirm a fat-containing mass).
T2-weighted images optimally show fluid and abnormalities (e.g. tumors, inflammation, trauma).
In practice, T1- and T2-weighted images provide complementary information, so both are important for characterizing abnormalities.
Spine and extremity injuries are common among people of all ages and can have a significant impact on mobility and quality of life. This PowerPoint presentation provides a comprehensive overview of spine and extremity injuries, including the causes, symptoms, and treatment options.
Through powerful images and personal stories, we showcase the impact of spine and extremity injuries on individuals, families, and communities. We highlight the challenges of accessing healthcare and rehabilitation services, particularly in low-resource settings, and the importance of early intervention and treatment.
The presentation provides detailed information about the various types of spine and extremity injuries, including fractures, dislocations, and soft tissue injuries. We also discuss the diagnostic procedures, including imaging tests and physical exams, and the treatment options, such as surgery, physical therapy, and pain management.
In addition, we explore the efforts being made to prevent and manage spine and extremity injuries. We highlight the importance of safety precautions, such as proper equipment use and ergonomic work practices, and the role of rehabilitation services in promoting recovery and restoring function.
Through this PowerPoint presentation, we aim to raise awareness about spine and extremity injuries and the importance of early diagnosis and treatment. We showcase the latest research and innovations in injury prevention and treatment, and the importance of collaboration and partnership to address the disease.
We urge the audience to take action in the fight against spine and extremity injuries, whether it be through spreading awareness, supporting organizations working on the ground, or advocating for policy change. Let us come together to create a world where everyone has access to the care and support they need to recover from spine and extremity injuries and live healthy, fulfilling lives.
Brain tumours are responsible for approximately
2% of all cancer deaths. Central nervous system
tumours comprise the most common group of
solid tumours in young patients, accounting for
20% of all paediatric neoplasms. The overall incidence
of brain tumours is 8–10 per 100 000 population
per year. A study by the United States
Department of Health in 1966 showed the incidence
to be 21 per 100 000 per year at 2 years old
and 1 per 100 000 during the teenage years. The
incidence increases after the 4th decade of life to
reach a maximum of 16 per 100 000 per year in the
7th decade. There has been an intense debate concerning
the increased incidence of brain tumours,
especially in the elderly, but this possible increase
could be explained due to the advent of CT and
MRI leading to better detection of tumours.
Classification
The general brain tumour classification is related
to the cell of origin, and is shown in Table 6.1.
Table 6.2 shows the approximate distribution
of the more common brain tumours.
This chapter will discuss the tumours derived
from the neuroectoderm and metastatic tumours.
The following chapters will describe the benign
brain tumours and pituitary tumours.
Aetiology
Epidemiology studies have not indicated any
particular factor (viral, chemical or traumatic)
that causes brain tumours in humans, although a
range of cerebral tumours can be induced in animals
experimentally. There is no genetic predis
T1-weighted images optimally show normal soft-tissue anatomy and fat (e.g. to confirm a fat-containing mass).
T2-weighted images optimally show fluid and abnormalities (e.g. tumors, inflammation, trauma).
In practice, T1- and T2-weighted images provide complementary information, so both are important for characterizing abnormalities.
Spine and extremity injuries are common among people of all ages and can have a significant impact on mobility and quality of life. This PowerPoint presentation provides a comprehensive overview of spine and extremity injuries, including the causes, symptoms, and treatment options.
Through powerful images and personal stories, we showcase the impact of spine and extremity injuries on individuals, families, and communities. We highlight the challenges of accessing healthcare and rehabilitation services, particularly in low-resource settings, and the importance of early intervention and treatment.
The presentation provides detailed information about the various types of spine and extremity injuries, including fractures, dislocations, and soft tissue injuries. We also discuss the diagnostic procedures, including imaging tests and physical exams, and the treatment options, such as surgery, physical therapy, and pain management.
In addition, we explore the efforts being made to prevent and manage spine and extremity injuries. We highlight the importance of safety precautions, such as proper equipment use and ergonomic work practices, and the role of rehabilitation services in promoting recovery and restoring function.
Through this PowerPoint presentation, we aim to raise awareness about spine and extremity injuries and the importance of early diagnosis and treatment. We showcase the latest research and innovations in injury prevention and treatment, and the importance of collaboration and partnership to address the disease.
We urge the audience to take action in the fight against spine and extremity injuries, whether it be through spreading awareness, supporting organizations working on the ground, or advocating for policy change. Let us come together to create a world where everyone has access to the care and support they need to recover from spine and extremity injuries and live healthy, fulfilling lives.
Foot and ankle trauma, common pitfalls, imaging modalities and radiographic occult fractures. The concept of the PITFL or "pitiful injury" an easily overlooked ligamentous injury of the talocrural joint
Foot and ankle trauma, common pitfalls, imaging modalities and radiographic occult fractures. The concept of the PITFL or "pitiful injury" an easily overlooked ligamentous injury of the talocrural joint
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
7. Common Ortho neurovascular injuries
• Anterior shoulder dislocation- axillary nerve (weak deltoid and numbness
around lateral upper arm
• Proximal humerus fx
– Located at surgical neck
– Treat with closed reduction and immobilization
– Above the tuberosities (anatomic neck) risks avascular necrosis
• Supracondylar fx of humerus- in kids, Volkmann’s ischemic contracture
(compartment syndrome), median nerve- anterior interosseous branch (and
artery), weak thenar muscles, wrist flexion and decreased sensation radial
palm and 3.5 fingers; brachial artery
• Midshaft humerus fx : radial nerve (20% injury rate with fx), closed fx, 90%
return of nerve function, open fx, nerve should be explored
• Posterior knee dislocation: popliteal artery injury- hard signs of vascular injury
require intervention, otherwise ABI. If >.9, rules out injury
• Distal radius fx: median nerve injury
• Fibular neck fx: common peroneal nerve- foot drop
8. Compartment syndrome
• Pain out of proportion to physical exam is the hallmark of extremity compartment syndrome
• Most commonly anterior compartment of the leg (foot drop)
– Pain on passive movement
– Pallor
– Pulselessness (LATE FINDING!)
– Paralysis
– Paresthesia
• Compartment pressure
– >30 mm Hg (lower if hypotensive)
• Ultimately a clinical diagnosis, compartment release if high index of suspicion
• Chronic exertional compartment syndrome
– Heavy , repetitive use
– Consistent history (similar to claudication)
– Compartment release successful in lower extremity
9.
10.
11. Treatment of open fx’s
• Irrigation and debridement
• Culture, then start antibiotics (orthocillin)
• Tetanus prophylaxis
• Stabilize fx
• Biggest risk of nonunion is smoking
12.
13.
14. Hydrofluoric acid burn
• Immediately severely painful
• Tissue penetration with necrosis of soft tissue and
bone erosion (binds Ca and Mg)
• Application of calcium gluconate gel binds F
• When severe, hypocalcemia common
15. Frostbite
• Essentially a burn, initial presentation for all depths is similar
• Classified by depth of damage to the skin (known after thawing)
– 1st degree- central whitish area surround by erythema
– 2nd degree- present with blisters within 24 hours
– 3rd degree- blisters progressing to eschar
– 4th degree- tissue necrosis
• Treatment
– Only rewarm when there is no risk of refreezing
– Rapid rewarming by submersion in warm (104-107.6 F) water for 15-30 min
– Tetanus prophylaxis and analgesia
– Pad and splint injured extremities
– Monitor for compartment syndrome
– IV or intra-arterial tPA within 24 hrs may reduce tissue loss
– Demarcation over 1-3 months with conservative debridement
16. Peripheral nerve injuries
• Neuropraxia
– Physiologic interruption of nerve conduction
– Stretch injury
– Good prognosis, recovery based on nerve length
• Axonotmesis
– Axonal and myelin loss with intact Schwann cell sheath
– Axon undergoes Wallerian degeneration
– Sensory loss with axonal regeneration 1 mm/day (1 inch/month)
– Fair prognosis
• Neurotmesis
– Complete division of nerve
– Spontaneous recovery impossible
– Repaired by precise apposition of nerve ends
17.
18. Spinal cord injury
(SCI)
• IV steroid protocol for blunt SCI only
– Based on time since injury
– <3 hrs, 3-8 hours, >8 hours
– for <3 hours- 30 mg bolus of methylprednisolone
(over 15 minutes) followed by 5.4 mg/kg/hr
infusion over 23 hours
– For 3-8 hours- 30 mg bolus, followed by 5.4
mg/kg/hr over 47 hours
– For >8 hours- no steroids
19. The controversy
Following the NASCIS trials, the use of high-dose methylprednisolone
in nonpenetrating acute SCI had become the standard of care in North
America. Nesathurai and Shanker revisited these studies and
questioned the validity of the results.[45] These authors cited concerns
about the statistical analysis, randomization, and clinical endpoints
used in the study. In addition, the investigators noted that even if the
benefits of steroid therapy were valid, the clinical gains were
questionable. Other reports have also cited flaws in the study designs,
trial conduct, and final presentation of the data.
The risks of steroid therapy are not inconsequential. An increased
incidence of infection and avascular necrosis has been documented.
20. Revised recommendations
The Congress of Neurological Surgeons (CNS) has stated that steroid therapy "should only
be undertaken with the knowledge that the evidence suggesting harmful side effects is
more consistent than any suggestion of clinical benefit.“ The American College of Surgeons
(ACS) has modified their advanced trauma life support (ACLS) guidelines to state that
methylprednisolone is "a recommended treatment" rather than "the recommended
treatment." The Canadian Association of Emergency Physicians (CAEP) is no longer
recommending high-dose methylprednisolone as the standard of care.
In a survey conducted by Eck and colleagues, 90.5% of spine surgeons surveyed used
steroids in SCI, but only 24% believed that they were of any clinical benefit.[49] Note that
the investigators not only discovered that approximately 7% of spine surgeons do not
recommend or use steroids at all in acute SCI, but that most centers were following the
NASCIS II trial protocol.
Updated guidelines issued in 2013 by the CNS and the American Association of Neurological
Surgeons (AANS) recommend against the use of steroids early after an acute SCI. The
guidelines recommend that methylprednisolone not be used for the treatment of acute SCI
within the first 24-48 hours following injury. The previous standard was revised because of a
lack of medical evidence supporting the benefits of steroids in clinical settings and evidence
that high-dose steroids are associated with harmful adverse effects.
21. Summary
• Overall, the benefit from steroids is considered modest at best, but for
patients with complete or incomplete quadriplegia, a small improvement
in motor strength in one or more muscles can provide important
functional gains.
• The administration of steroids remains an institutional and physician
preference in spinal cord injury. Nevertheless, the administration of high-
dose steroids within 8 hours of injury for all patients with acute spinal cord
injury is practiced by most physicians.
• The current recommendation is to treat all patients with spinal cord injury
according to the local/regional protocol. If steroids are recommended,
they should be initiated within 8 hours of injury with the following steroid
protocol: methylprednisolone 30 mg/kg bolus over 15 minutes and an
infusion of methylprednisolone at 5.4 mg/kg/h for 23 hours beginning 45
minutes after the bolus.
22. Ortho tumors
• Multiple myeloma (malignant)
– Most common primary bone tumor- (neg bone scan)
• Osteoid Osteoma (benign)
– Teenagers (2nd decade)
– Presents at night (often back pain) relieved with salicylates
– Common in posterior elements of the spine
• Osteosarcoma (malignant)
– 2nd decade of life, distal femur most common location (then prox tibia)
– “Codman triangle” cortical destruction (“sunburst”)
– Hematogenous spread (mets to lung most common)
– Neoadjuvant chemo then en bloc resection (reconstruction vs amputation)
– Can arise from Paget bone disease in the elderly
• Enchondroma (benign)
– Benign neoplasm arising from cartilage (“popcorn” calcification)
– May be multiple (Ollier disease), with soft tissue hemangiomas (Maffucci syndrome)
• Chondroblastoma (benign)
– First and second decade (before epiphyseal closure) at the epiphysis
– Treat with curettage and bone grafting
• Chondrosarcoma (malignant)
– Malignant adult bone lesion (shoulder, pelvic girdle, knee, spine)
– Pain and/or mass present (“popcorn” calcifications)
– Wide resection
• Giant cell tumor (benign but locally aggressive)
– Xray shows eccentric lytic lesions in epiphysis
– Knee and distal radius most common
– Treat with curettage
– Can metastasize to the lungs (4%) but rarely fatal
• Unicameral bone cyst (benign)
– proximal humerus most common site (proximal femur, distal tibia)
– Occurs during rapid bone growth
– Treat with methyl prednisolone acetate injection
26. Ortho tumors (cont)
• Aneurysmal Bone cyst (benign)
– Osteolytic metaphyseal lesion
– Blood-filled cavernous spaces within fibrous tissue, no endothelial lining
– Curettage and bone grafting
• Ewing tumor (malignant)
– Arises from diaphyseal marrow of long bones
– Patients < 20 years old
– “Onion skinning” appearance on Xray
– Lymphatic and hematogenous spread (mets to lung)
• Chordoma (malignant)
– Back pain with loss of rectal tone
– Midline destructive lesion of sacrum with soft tissue mass (may be palpable)
– Arises of embryonic remnants of notochord
– Surgical excision
• Rhabdomysosarcoma (malignant)
– Patients < 20 years old
– Arises from striated muscle
– Hematogenous spread
– Chemo with WLE
• Most common cancers that metastasize to bone
– #1) Breast
– #2) Prostate
– Thyroid
– Lung
– Kidney
• Bone scan is the most sensitive test for metastatic disease in the bone
27.
28. Random ortho facts
• Superior gluteal artery ligated with posterior iliac crest bone graft
• Most common organism in hand infections- staph aureus
• Organisms in septic arthritis
– Staph aureus
– Hemolytic strep
– Diagnosis after joint aspiration and gram stain
• Gonococcal arthritis
– Most common in females
– Migrating polyarthralgia
– Commonly involves knee, elbow, wrist
– Treat with 2 weeks of PCN and joint immobilization
• Spinal TB
– Pott disease (thoracic spine, anterior vertebral body)
– Insidious onset, worst pain at night
– Treat with antibiotics, rest, bracing
– Surgery for instability, neuro deficit, progressive kyphosis
• Gout
– Most common first metatarsal phalangeal (MTP) joint (great toe)
– Negative birefringence of rod-shaped urate crystals under polarized light (diagnostic)
– Treat with rest, NSAID’s
– Colchicine and allopurinol take time to work and are used as maintenance therapy
– Congenital Pyrophospate Disorder (pseudogout) similar except
• Short, blunt rhomboid crystals that are weakly birefringent
• Most common joint is the knee
29. Random ortho facts (cont)
• Rheumatoid arthritis
– Ulnar “drift”
– 4th and 5th decade
– Autoimmune, treat with steroids or immune modulators
• Osteoarthritis
– Joint pain, Bouchard (PIP) and Heberden (DIP) nodes
– Decreased joint mobility due to articular cartilage destruction, loss of joint space
– Treat with NSAID’s, joint replacement
• Slipped capital femoral epiphysis
– Most common in adolescent males (11-15 yo), 25% bilateral, risk of avascular necrosis
– External rotation due to medial and posterior displacement of capital epiphysis
– Pain referred to the knee (and sometimes groin, with hip pathology this is common)
– X-ray: widening and irregularity of epiphyseal plate
– Pinning in situ
• Leg-Calve-Perthes disease
– Males 4-8 yo, limping
– Avascular necrosis of femoral head; 10% bilateral
– X-ray: flattening of femoral head
– Treat with maintenance of motion, femoral head will remodel with time
• Osgood-Schlatter Disease
– Males 13-15 yo, tibial tubercle pain (knee pain)
– Traction apophysitis; traction injury caused by quadriceps
– X-ray: Irregular shape or fragmenting of tibial tubercle
– Mild symptoms: limit activity; Severe symptoms: cast for 6 weeks
• Charcot Joint
– Joint destruction caused by inability to sense required wt distribution
– Neuro disorders, diabetes most common cause
30. Ortho facts (cont)
• Rotator cuff muscles
• S upraspinatus
• I nfraspinatus
• T eres minor
• S ubscapularis
• Ligaments in acromioclavicular (AC) separation
• Coracoclavicular
• Acromioclavicular
• Clavicular fx
• Most common site is middle third
• Treat with sling and gentle ROM
• Main risk of fx is vascular impingement
• If >2cm shortening or open, ORIF
• Tennis elbow- lateral epicondylitis of the extensor carpi radialis brevis
• Scaphoid fx- fall on outstretched hand
• Pain in the anatomic snuff box
• May not be detected on immediate Xray (repeat Xray in three weeks or MRI/bone scan for dx)
• Treat with long arm thumb “spica” cast
• High incidence of avascular necrosis
• Nursemaid’s Elbow
• Usually traction injury from pulling up on a toddler’s hand
• Dislocation of the radial head (at the elbow)
• Reduced by flexing arm 90 degrees, supinating the arm, applying posterior force and extending the arm
• Audible “clunk” (sometimes)
31. Ortho facts (cont)
• Chance fx – associated with seatbelt (flexion) fx of lumbar spine
• Must rule out intraabdominal injury (specifically small bowel)
• Colles Fracture- distal radius fx from fall on outstretched hand
• Treat with closed reduction
• Monteggia fx- proximal ulna with radial head dislocation
• Also an outstretched hand
• Treat with ORIF
• Carpal tunnel
• Entrapment of medial nerve at the wrist
• Thenar atrophy
• Positive Tinel sign and Phalen maneuver
• Intial RX with splinting , NSAID’s, then surgery for carpal tunnel release
• Ganglion cyst- most common site is dorsal wrist
• Game keeper thumb (skiers)- disruption of ulnar collateral ligament of the
MCP of thumb
• Boutonniere Deformity- disruption of central extensor tendon, lateral
bands displace toward the palm causing PIP flexion and DIP extension
• Mallet deformity- DIP extensor tendon rupture
• Median, Ulnar, and Radial Nerve innervation
32.
33.
34.
35.
36. Ortho facts (cont)
• Type I collagen- bone (skin, tendon, dentin, primary collagen of wound healing
• Mutations result in osteogenesis imperfecta
• Type II collagen- articular cartwolage (vitreous humor)
• Type III collagen- skin, muscles and blood vessels
• Type IV collagen- basement membrane
• Type V collagen- cornea
37. Hip dislocations/fx
•Anterior hip dislocations may present in 2 different ways.
– Superiorly displaced dislocations present with the affected hip
extended and externally rotated
– The inferior type of anterior dislocations presents with the
affected hip flexed, abducted, and externally rotated.
•Posterior hip dislocation most commonly appears
shortened, internally rotated, and adducted.
• Femoral neck fx
– Alignment and length of the extremity is usually normal;
however, the classic presentation of patients with displaced
fractures is a shortened and externally rotated extremity.
– High risk for avascular necrosis of the femoral head