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ORGAN PRESERVATION BY RADIOTHERAPY
Dr.KANHU CHARAN PATRO
MD, DNB[RADIATION ONCOLOGY] MBA, PDCR, CEPC
• Cancer is the second leading cause of death.
• Globally, By 2020, there will be 20 million new cancer patients each
year.
• In the U.S., there are 1.25 million new cancer cases annually
 198,100 prostate  192,200 breast
 169,500 lung  135,400 colorectal
• In 2001, U.S. cancer mortality will be about 553,400 --over 1,500
people a day.
• In the US, men have about a one in two lifetime risk of developing
cancer; for women the risk is about one in three.
2/2/2018 3:45:08 AM 2
Cancer Facts
? ?
2/2/2018 3:45:08 AM 3
Oncologist
Diagnosis
Treatment
Radiologist
Cytopathologist
Surgeon
HistopathologistMolecular
Pathologist
Geneticist
psychiatrist
Nursing
And
Support staff
Audit
Evolution of
radiotherapy
treatment
2/2/2018 3:45:08 AM 8
2/2/2018 3:45:08 AM 9
Radiation –Part of life
2/2/2018 3:45:08 AM 10
Wilhelm Conrad Rontgen
History - radiation
1896 – Becquerel - Radioactivity
1898 – Madam Curie / Pierre Curie - Radium
1903 – Nobel Prize for Curie’s & Becquerel
1903 – First successful case of malignancy basal
cell carcinoma of face
2/2/2018 3:45:08 AM 11
GOALS
 High dose to tumor tissue-Tumor control
 Normal tissue sparing
 Minimize long and short term toxicities
 Better Quality of life
2/2/2018 3:45:08 AM 12
• COSMETIC DEFECT
• FUNCTIONAL DEFECT
• IMPAIRED QUALITY OF LIFE
SURGERY
2/2/2018 3:45:08 AM 13
RADIOTHERAPY
• CONVENTIONAL
• 3DCRT
• IMRT
• IGRT
• VMAT/RAPIDARC
• PET GUIDED RADIOTHERAPY
2/2/2018 3:45:08 AM 19
2/2/2018 3:45:08 AM 20
BRACHYTHERAPY
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2/2/2018 3:45:08 AM 22
2/2/2018 3:45:08 AM 23
PROCEDURE
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IMAGING AND PLANNING
2/2/2018 3:45:08 AM 25
ISODOSE
TREATMENT DELIVERY
• HEAD AND NECK CANCERS
• BREAST CANCERS
• ESOPHAGUS CANCERS
• PENILE CANCER
• SOFT TISSUE SARCOMA
• BLADDER CANCERS
• CANAL CANCERS
ORGAN PRESERVATION
2/2/2018 3:45:08 AM 28
ORGAN PRESERVATION FOR
BONE TUMORS
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ORGAN PRESERVATION FOR
BREAST CANCERS
2/2/2018 3:45:08 AM 33
2/2/2018 3:45:08 AM 34
Intra- operative Brachytherapy
procedure
2/2/2018 3:45:08 AM 35
Intra- operative Brachytherapy
procedure
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Intra- operative Brachytherapy
procedure
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Intra- operative Brachytherapy
procedure
2/2/2018 3:45:08 AM 38
3D Brachytherapy Planning
CT Loading Dose distribution
2/2/2018 3:45:08 AM 39
Dose prescription and Treatment
delivery
• Dose: 34Gy in 10 fraction bid
• Dose per fraction: 340cGy
ORGAN PRESERVATION FOR
PENILE CANCERS
2/2/2018 3:45:08 AM 40
2/2/2018 3:45:08 AM 41
2/2/2018 3:45:08 AM 42
2/2/2018 3:45:08 AM 43
2/2/2018 3:45:08 AM 44
ORGAN PRESERVATION FOR
SARCOMAS
2/2/2018 3:45:08 AM 45
2/2/2018 3:45:08 AM 46
2/2/2018 3:45:08 AM 47
2/2/2018 3:45:08 AM 48
2/2/2018 3:45:08 AM 49
2/2/2018 3:45:08 AM 50
ORGAN PRESERVATION FOR
CANCER CERVIX [STAGE
0,EARLY 1]
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2/2/2018 3:45:08 AM 52
2/2/2018 3:45:08 AM 53
ICA HDR application
2/2/2018 3:45:08 AM 54
2/2/2018 3:45:08 AM 55
2/2/2018 3:45:08 AM 56
ORGAN PRESERVATION FOR
CANCER ANAL CANAL
2/2/2018 3:45:08 AM 57
APR
2/2/2018 3:45:08 AM 58
ANAL CANAL BRACHYTHERAPY
2/2/2018 3:45:08 AM 59
ORGAN PRESERVATION FOR
CANCER TONGUE
2/2/2018 3:45:08 AM 60
2/2/2018 3:45:08 AM 61
TONGUE IMPLANT IN PROGRESS
2/2/2018 3:45:08 AM 62
TONGUE IMPLANT IN PROGRESS
2/2/2018 3:45:08 AM 63
2/2/2018 3:45:08 AM 64
ORGAN PRESERVATION FORCANCER LIP
2/2/2018 3:45:08 AM 65
2/2/2018 3:45:08 AM 66
2/2/2018 3:45:08 AM 67
Applicator in situ with IOP
Complete response –towards healing
hypo-pigmentation
Recent
2/2/2018 3:45:08 AM 71
2/2/2018 3:45:08 AM 72
KELOIDS
2/2/2018 3:45:08 AM 73
CANCER ESOPHAGUS
2/2/2018 3:45:08 AM 74
ESOPHAGEAL BRACHYTHERAPY
2/2/2018 3:45:08 AM 75
2/2/2018 3:45:08 AM 76
ILRT-dosimetry
BASE OF TONGUE
2/2/2018 3:45:08 AM 77
PROSTATE CANCER
2/2/2018 3:45:08 AM 78
2/2/2018 3:45:08 AM 79
2/2/2018 3:45:08 AM 80
2/2/2018 3:45:08 AM 81
OCULAR MELANOMA
RETINOBLASTOMA
2/2/2018 3:45:08 AM 82
2/2/2018 3:45:08 AM 83
2/2/2018 3:45:08 AM 84
2/2/2018 3:45:08 AM 85
2/2/2018 3:45:08 AM 86
2/2/2018 3:45:08 AM 87
2/2/2018 3:45:08 AM 88
2/2/2018 3:45:08 AM 89
2/2/2018 3:45:08 AM 90
2/2/2018 3:45:08 AM 91
2/2/2018 3:45:08 AM 92
2/2/2018 3:45:08 AM 93
• GOOD COSMETIC
• FUNCTIONAL PRESERVATION
• GOOD QUALITY OF LIFE
• ESTABLISHED PROCEDURE
• EXPERTISE REQUIRED
• AVAILABLE LITERATURES
• LESS TOXIC
FACTS
2/2/2018 3:45:08 AM 94
SMART THINKING
2/2/2018 3:45:08 AM 95
2/2/2018 3:45:08 AM 96
10/20/12 01:12 PM 97
Just “Doing It” is not good enough !
You must know “what” to do and “where” to do it !
10/20/12 01:12 PM 98
10/20/12 01:12 PM 99
10/20/12 01:12 PM 100
10/20/12 01:12 PM 101
Whenever not
possible,
make friends
10210/20/12 01:12 PM
10310/20/12 01:12 PM
Guess
•What next
105
?

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