OMICS Publishing Group journal,Chemotherapy deals with the study & treatment of diseases using chemical agents/drugs, that are selectively toxic to the causative agent of the disease.
Colin Mansfield is a British citizen currently working as a Principal Medical Writer and IP Manager in Paris, France. He has over 20 years of experience in medical writing, intellectual property management, and research. His background includes a Ph.D. in Biomedical Physics, M.Sc. in Medical Physics, and B.Sc. in Physics with Astrophysics. He has authored over 25 articles and book chapters, and has received several awards and fellowships for his research work.
OMICS Publishing Group, Journal of Epidemiology is an Open Access, peer-reviewed journal which aims to provide the most rapid and reliable source of information on current developments in the field of Epidemiology.
Marcus Yaffee, PhD will present "Multimodal Imaging Probes For Research, Diagnostics and Therapeutics" on Tuesday, August 11th, 2015 from 4:00-5:00pm at the HMRI Research Conference Center located at 734 Fairmount Avenue in Pasadena, CA. The presentation will discuss the development and validation of new imaging probes for biomedical research and clinical applications, including the design and synthesis of modular biocompatible mixed-metal nanoparticle composites for multimodal imaging using PET/MRI/CT. Case studies demonstrating the function of imaging markers will be presented.
Patients' Organizations Italian MS Society and its Foundation - P. Zaratin (D...Sardegna Ricerche
L'intervento di Paola Zaratin (Director of Scientific Research) in occasione dell'evento "Il valore della ricerca biomedica" che si è tenuto a Pula (CA) il 3 aprile 2019.
Clinical pharmacists can play an active role in regulatory clinical trials by assisting in various tasks such as monitoring adverse drug reactions, ensuring protocol compliance, answering drug-related medical questions from investigators and patients, and supporting investigators in submitting documentation to regulatory agencies and institutional review boards. Their involvement helps improve patient safety and data quality while reducing investigators' workload.
OMICS Publishing Group, Journal of Nanomedicine & Biotherapeutic Discovery (JNBD) is an international, peer-reviewed journal. Each issue of Journal of Nanomedicine & Biotherapeutic Discovery presents basic, clinical, and engineering research in the field of nanomedicine and the related biotherapeutic discovery. The regular features addresses the commercialization of nanomedicine advances, ethics in nanomedicine, funding opportunities, and other topics of interest to researchers and clinicians.
Integrative Cancer - New theories and Advances in Treatment From Hippocrates ...Sheldon Stein
Professor Serge Jurasunsas' recent paper on Integrative Cancer, From Hippocrates to the Human Genome - posted on his behalf. Discusses testing, protocols and case discussion.
The document discusses different classes of metabolic pathways that can be targeted by antimicrobial drugs. Class I reactions involve glucose metabolism and are not promising targets as bacteria can use alternative carbon sources. Class II reactions involve small molecule synthesis and some pathways only exist in microbes, making them better targets. Class III reactions like peptidoglycan synthesis, protein synthesis and nucleic acid synthesis are particularly good targets as bacteria must produce these molecules themselves. The document then provides more details on mechanisms of several antimicrobial drugs that target bacterial cell wall, protein and DNA/RNA synthesis.
Colin Mansfield is a British citizen currently working as a Principal Medical Writer and IP Manager in Paris, France. He has over 20 years of experience in medical writing, intellectual property management, and research. His background includes a Ph.D. in Biomedical Physics, M.Sc. in Medical Physics, and B.Sc. in Physics with Astrophysics. He has authored over 25 articles and book chapters, and has received several awards and fellowships for his research work.
OMICS Publishing Group, Journal of Epidemiology is an Open Access, peer-reviewed journal which aims to provide the most rapid and reliable source of information on current developments in the field of Epidemiology.
Marcus Yaffee, PhD will present "Multimodal Imaging Probes For Research, Diagnostics and Therapeutics" on Tuesday, August 11th, 2015 from 4:00-5:00pm at the HMRI Research Conference Center located at 734 Fairmount Avenue in Pasadena, CA. The presentation will discuss the development and validation of new imaging probes for biomedical research and clinical applications, including the design and synthesis of modular biocompatible mixed-metal nanoparticle composites for multimodal imaging using PET/MRI/CT. Case studies demonstrating the function of imaging markers will be presented.
Patients' Organizations Italian MS Society and its Foundation - P. Zaratin (D...Sardegna Ricerche
L'intervento di Paola Zaratin (Director of Scientific Research) in occasione dell'evento "Il valore della ricerca biomedica" che si è tenuto a Pula (CA) il 3 aprile 2019.
Clinical pharmacists can play an active role in regulatory clinical trials by assisting in various tasks such as monitoring adverse drug reactions, ensuring protocol compliance, answering drug-related medical questions from investigators and patients, and supporting investigators in submitting documentation to regulatory agencies and institutional review boards. Their involvement helps improve patient safety and data quality while reducing investigators' workload.
OMICS Publishing Group, Journal of Nanomedicine & Biotherapeutic Discovery (JNBD) is an international, peer-reviewed journal. Each issue of Journal of Nanomedicine & Biotherapeutic Discovery presents basic, clinical, and engineering research in the field of nanomedicine and the related biotherapeutic discovery. The regular features addresses the commercialization of nanomedicine advances, ethics in nanomedicine, funding opportunities, and other topics of interest to researchers and clinicians.
Integrative Cancer - New theories and Advances in Treatment From Hippocrates ...Sheldon Stein
Professor Serge Jurasunsas' recent paper on Integrative Cancer, From Hippocrates to the Human Genome - posted on his behalf. Discusses testing, protocols and case discussion.
The document discusses different classes of metabolic pathways that can be targeted by antimicrobial drugs. Class I reactions involve glucose metabolism and are not promising targets as bacteria can use alternative carbon sources. Class II reactions involve small molecule synthesis and some pathways only exist in microbes, making them better targets. Class III reactions like peptidoglycan synthesis, protein synthesis and nucleic acid synthesis are particularly good targets as bacteria must produce these molecules themselves. The document then provides more details on mechanisms of several antimicrobial drugs that target bacterial cell wall, protein and DNA/RNA synthesis.
Principles of medical_oncology dr. varunVarun Goel
- The document discusses several key principles of medical oncology including that cancer treatment is multidisciplinary, early stage cancers are more curable than late stage, and the best treatment is often found in clinical trials.
- It describes the basic tenets of chemotherapy including that it can be used for induction treatment of advanced cancers or as adjuvant treatment after local therapy to treat high risk of recurrence. The intent of chemotherapy can be curative or palliative.
- Several models of tumor growth and response to chemotherapy are explained including the Skipper-Wilcox model, concepts of combination chemotherapy, and the Goldie-Coldman model regarding emergence of drug resistance with increased tumor size.
Chemotherapy uses chemicals to inhibit microbial growth. It is often used with other treatments like biological therapies, radiation, and surgery. Chemotherapeutic agents target differences between parasites and host cells to be toxic to parasites while sparing host cells. Resistance can develop through genetic changes in microbes. Chemotherapy works by targeting microbial biochemical reactions, cell structures, and genetic material. Selection of antimicrobial agents requires knowledge of the infecting organism and site of infection.
Chemotherapy drugs work by damaging DNA or inhibiting DNA synthesis in rapidly dividing cancer cells. While chemotherapy has improved survival for some cancers, resistance often develops and toxic side effects limit doses. Combination regimens using different drug classes aim to overcome resistance, but incremental improvements have plateaued. Recent focus is on molecularly targeted agents addressing specific cancer pathways to potentially achieve greater effects with less toxicity.
1. Chemotherapy uses cytotoxic drugs to kill cancer cells or stop their growth by interfering with cell division. It is indicated when cancer has spread and cannot be treated with surgery or radiation alone.
2. There are several classes of chemotherapeutic drugs including antimetabolites, alkylating agents, antibiotics, and microtubule inhibitors. Antimetabolites interfere with DNA and RNA production. Alkylating agents damage DNA to cause cell death. Antibiotics and microtubule inhibitors affect DNA/RNA and microtubule formation.
3. Side effects of chemotherapy can include bone marrow suppression, nausea, vomiting, alopecia, and organ-specific toxicities depending on the drug. Cancer cells can also
Norbert Sipos: Principles of cancer therapyKatalin Cseh
The document discusses principles of cancer therapy including chemotherapy and radiation therapy. It covers topics like evaluating malignancies, determining likelihood of response to treatment, cell cycle specifics of chemotherapy, and principles of combination chemotherapy. The document also provides details on treating specific cancers like vulvar cancer through surgery, radiation, and chemotherapy.
1) Recent advances in cancer chemotherapy include the development of newer alkylating agents, platinum compounds, antimetabolites, mitotic spindle inhibitors, and topoisomerase inhibitors with improved efficacy and reduced toxicity profiles.
2) Many newer agents aim to overcome resistance to existing drugs by bypassing drug efflux pumps or having activity in cisplatin/taxane resistant settings.
3) Several new drugs have received FDA approval in the last decade for cancers like breast cancer, lung cancer, and leukemia, offering additional treatment options.
medicinal chemistry of Anticancer agentsGanesh Mote
1) Cancer is caused by abnormal cells dividing uncontrollably and spreading to other tissues. Chemotherapy uses drugs to kill cancer cells or slow their growth.
2) There are several types of chemotherapy drugs that work through different mechanisms such as alkylating agents, antimetabolites, plant-derived products, and monoclonal antibodies.
3) Alkylating agents work by adding alkyl groups to DNA, damaging its structure and preventing cell division. Common alkylating agents include cyclophosphamide, cisplatin, and carmustine.
Principles of chemotherapy(types, indications and complications)ashirwad karigoudar
This document provides an overview of the principles of chemotherapy. It discusses the historical origins of chemotherapy beginning in the 1960s when combination chemotherapy was found to cure childhood leukemias and lymphomas. It also addresses the main obstacles of toxicity and drug resistance. The document then covers the clinical applications of chemotherapy including primary induction, neoadjuvant, adjuvant, and site-directed treatments. It concludes by discussing principles of cancer kinetics, drug resistance biology, and methods for assessing clinical response.
1. The document is a chemotherapy preparation and stability chart that provides information for reconstituting and administering various chemotherapy drugs, including diluents, concentrations, storage times and temperatures, and special precautions.
2. Drugs listed include aldesleukin, alemtuzumab, amsacrine, asparaginase, azacitidine, BCG, bendamustine, bevacizumab, bleomycin, bortezomib, busulfan, carboplatin, and others. Information provided for each includes reconstitution details, concentrations for administration, storage details for vials and final products, and any special handling notes.
3. The chart is a valuable resource for
Principles of cancer chemotherapy and its clinical evaluationjyotimannath
Dr. Jyotiman Nath presented on the history and development of cancer chemotherapy. Some key points include:
- Chemotherapy originated in the early 20th century with Paul Ehrlich's work on "magic bullets" to treat infections. Sidney Farber is considered the father of modern chemotherapy.
- During World Wars I and II, exposure of soldiers to mustard gas led to the observation that alkylating agents suppressed bone marrow, laying the foundations for using similar agents to treat cancers.
- In the 1940s and 50s, drugs like methotrexate and combinations of drugs were used successfully to treat various cancers, representing major advances in the field.
- Current chemotherapy typically involves combinations of
1. The document discusses various types of chemotherapy agents used to treat cancer, including alkylating agents, antimetabolites, plant-derived products, antibiotics, and hormones.
2. It explains the mechanisms of action of alkylating agents and antimetabolites, describing how alkylating agents transfer alkyl groups to damage DNA and how antimetabolites compete for binding sites to interfere with cell growth.
3. The document provides classifications of chemotherapy drugs and examples within each classification, including cell cycle specific and non-specific agents.
This document summarizes various classes and subclasses of cancer chemotherapy drugs, including their mechanisms of action, toxicities, and therapeutic uses. It discusses cell cycle-specific agents like alkylating agents, antimetabolites, plant alkaloids, and hormones. Alkylating agents like cyclophosphamide can alkylate DNA. Antimetabolites like methotrexate and 5-fluorouracil interfere with DNA synthesis. Plant alkaloids including vinca alkaloids and taxanes affect microtubules. Hormonal therapies include tamoxifen, aromatase inhibitors, and gonadotropin-releasing hormone agonists. The document provides detailed information on numerous chemotherapy drugs.
CANCER: A group of disease involving abnormal cell growth with the potential to invade or spread to other part of the body.
CHEMOTHERAPY: the term chemotherapy is describe as the use of chemicals or drugs to treat cancer.
CYTOTOXIC DRUG: lysis both normal and cancer cells
Antineoplastic agents can be classified as cytotoxic drugs, hormones, or miscellaneous agents. Cytotoxic drugs include alkylating agents, antimetabolites, plant derivatives, and antibiotics. They work by directly damaging DNA or interfering with cell division and metabolism. Combination therapy is more effective than single agents to increase response rates and decrease resistance development.
The document discusses principles of chemotherapy including stages of mitosis, classification of cytotoxic agents, their action sites in the cell cycle and at the cellular level, metabolism and resistance mechanisms of cyclophosphamide as an example, and combination therapy aims to increase efficacy while managing side effects.
The document discusses various types of antineoplastic agents (anticancer drugs) that are used to treat cancer. It describes how the drugs work, their classifications, mechanisms of action, examples of drugs within each class, dosages and side effects. The classes discussed include alkylating agents, antimetabolites, vinka alkaloids, taxanes, epipodophyllotoxins, antibiotics, and miscellaneous cytotoxic drugs.
ANTI CANCER DRUGS[ANTI-NEOPLASTIC DRUGS] MEDICINAL CHEMISTRY BY P. RAVISANKAR.Dr. Ravi Sankar
The document discusses antineoplastic agents (anticancer drugs) and provides information on cancer and its diagnosis and treatment. It defines cancer as uncontrolled cell growth and discusses how cancer is classified. It also summarizes some common cancer types in children and adults. The document outlines several methods used to treat cancer, including surgery, radiation therapy, immunotherapy, hormonal therapy, chemotherapy and antibiotics. It provides classifications of antineoplastic drugs and examples.
The document categorizes and describes various classes of drugs used in cancer chemotherapy, including their mechanisms of action, pharmacokinetics, adverse effects, and clinical uses. It discusses cytotoxic drugs that act directly on cells like alkylating agents, antimetabolites, vinca alkaloids, taxanes, and antibiotics. It also covers drugs that alter the hormonal milieu and miscellaneous drugs like hydroxyurea. For each class, it provides one or more examples and describes in detail the example drug's mechanism, pharmacokinetics, adverse effects and clinical applications.
This document provides information about a special issue of the International Journal of Cancer Studies & Research focused on chemotherapy and radiology. The issue will include original research articles, short communications, mini-reviews, and reviews covering topics like drug design, cancer therapeutic development approaches, chemotherapy, radiotherapy, telomerase, telomeres, anticancer therapeutics, pathway databases, EGFR signaling, and the Warburg effect. The guest editors are Juong G. Rhee from the University of Maryland and Praveen Kandi from ScieGen Pharmaceuticals Inc. Authors are invited to submit work reviewing all aspects of chemotherapy and radiation therapy, including pathogenesis, diagnosis, treatment, and infection control with anticancer drugs.
One way to alleviate the terrible side effects of chemotherapy is to find a way to better control what cells are needed
to be targeted by the drugs in cancer patients. By being able to target on ly the cancerous cells within the body, less
chemotherapy drugs would need to be injected into the patient for cancer treatment, thus reducing, if not completely
wiping away, the side effects of the chemotherapy drugs. Cancer researchers have figured out a method that better
delivers drugs, such as chemotherapy drugs, to cancer cells without damaging surrounding healthy ones, by
discovering a way to use single-walled carbon nanotubes (SWCNTs) as targeted medicinal delivery mediums. For
how small they are, their inner volumes are relatively large, leaving enough space to carry drugs into the body. Both
the inner and outer surfaces of SWCNTs can be easily modified for “functionalization”. Their small size nature
allows them to enter the nuclei of cells freely. Most importantly, single-walled carbon nanotubes are completely safe
and nontoxic and proven to be stable to use in inserting and transporting drugs into the body. Presently, carbon
nanotubes are not only being used as drug delivery systems, but as a means of directly killing malignant cells within
the body. All of these applications of CNTs makes it promising and would lead to great advances in medicine in the
future.
Principles of medical_oncology dr. varunVarun Goel
- The document discusses several key principles of medical oncology including that cancer treatment is multidisciplinary, early stage cancers are more curable than late stage, and the best treatment is often found in clinical trials.
- It describes the basic tenets of chemotherapy including that it can be used for induction treatment of advanced cancers or as adjuvant treatment after local therapy to treat high risk of recurrence. The intent of chemotherapy can be curative or palliative.
- Several models of tumor growth and response to chemotherapy are explained including the Skipper-Wilcox model, concepts of combination chemotherapy, and the Goldie-Coldman model regarding emergence of drug resistance with increased tumor size.
Chemotherapy uses chemicals to inhibit microbial growth. It is often used with other treatments like biological therapies, radiation, and surgery. Chemotherapeutic agents target differences between parasites and host cells to be toxic to parasites while sparing host cells. Resistance can develop through genetic changes in microbes. Chemotherapy works by targeting microbial biochemical reactions, cell structures, and genetic material. Selection of antimicrobial agents requires knowledge of the infecting organism and site of infection.
Chemotherapy drugs work by damaging DNA or inhibiting DNA synthesis in rapidly dividing cancer cells. While chemotherapy has improved survival for some cancers, resistance often develops and toxic side effects limit doses. Combination regimens using different drug classes aim to overcome resistance, but incremental improvements have plateaued. Recent focus is on molecularly targeted agents addressing specific cancer pathways to potentially achieve greater effects with less toxicity.
1. Chemotherapy uses cytotoxic drugs to kill cancer cells or stop their growth by interfering with cell division. It is indicated when cancer has spread and cannot be treated with surgery or radiation alone.
2. There are several classes of chemotherapeutic drugs including antimetabolites, alkylating agents, antibiotics, and microtubule inhibitors. Antimetabolites interfere with DNA and RNA production. Alkylating agents damage DNA to cause cell death. Antibiotics and microtubule inhibitors affect DNA/RNA and microtubule formation.
3. Side effects of chemotherapy can include bone marrow suppression, nausea, vomiting, alopecia, and organ-specific toxicities depending on the drug. Cancer cells can also
Norbert Sipos: Principles of cancer therapyKatalin Cseh
The document discusses principles of cancer therapy including chemotherapy and radiation therapy. It covers topics like evaluating malignancies, determining likelihood of response to treatment, cell cycle specifics of chemotherapy, and principles of combination chemotherapy. The document also provides details on treating specific cancers like vulvar cancer through surgery, radiation, and chemotherapy.
1) Recent advances in cancer chemotherapy include the development of newer alkylating agents, platinum compounds, antimetabolites, mitotic spindle inhibitors, and topoisomerase inhibitors with improved efficacy and reduced toxicity profiles.
2) Many newer agents aim to overcome resistance to existing drugs by bypassing drug efflux pumps or having activity in cisplatin/taxane resistant settings.
3) Several new drugs have received FDA approval in the last decade for cancers like breast cancer, lung cancer, and leukemia, offering additional treatment options.
medicinal chemistry of Anticancer agentsGanesh Mote
1) Cancer is caused by abnormal cells dividing uncontrollably and spreading to other tissues. Chemotherapy uses drugs to kill cancer cells or slow their growth.
2) There are several types of chemotherapy drugs that work through different mechanisms such as alkylating agents, antimetabolites, plant-derived products, and monoclonal antibodies.
3) Alkylating agents work by adding alkyl groups to DNA, damaging its structure and preventing cell division. Common alkylating agents include cyclophosphamide, cisplatin, and carmustine.
Principles of chemotherapy(types, indications and complications)ashirwad karigoudar
This document provides an overview of the principles of chemotherapy. It discusses the historical origins of chemotherapy beginning in the 1960s when combination chemotherapy was found to cure childhood leukemias and lymphomas. It also addresses the main obstacles of toxicity and drug resistance. The document then covers the clinical applications of chemotherapy including primary induction, neoadjuvant, adjuvant, and site-directed treatments. It concludes by discussing principles of cancer kinetics, drug resistance biology, and methods for assessing clinical response.
1. The document is a chemotherapy preparation and stability chart that provides information for reconstituting and administering various chemotherapy drugs, including diluents, concentrations, storage times and temperatures, and special precautions.
2. Drugs listed include aldesleukin, alemtuzumab, amsacrine, asparaginase, azacitidine, BCG, bendamustine, bevacizumab, bleomycin, bortezomib, busulfan, carboplatin, and others. Information provided for each includes reconstitution details, concentrations for administration, storage details for vials and final products, and any special handling notes.
3. The chart is a valuable resource for
Principles of cancer chemotherapy and its clinical evaluationjyotimannath
Dr. Jyotiman Nath presented on the history and development of cancer chemotherapy. Some key points include:
- Chemotherapy originated in the early 20th century with Paul Ehrlich's work on "magic bullets" to treat infections. Sidney Farber is considered the father of modern chemotherapy.
- During World Wars I and II, exposure of soldiers to mustard gas led to the observation that alkylating agents suppressed bone marrow, laying the foundations for using similar agents to treat cancers.
- In the 1940s and 50s, drugs like methotrexate and combinations of drugs were used successfully to treat various cancers, representing major advances in the field.
- Current chemotherapy typically involves combinations of
1. The document discusses various types of chemotherapy agents used to treat cancer, including alkylating agents, antimetabolites, plant-derived products, antibiotics, and hormones.
2. It explains the mechanisms of action of alkylating agents and antimetabolites, describing how alkylating agents transfer alkyl groups to damage DNA and how antimetabolites compete for binding sites to interfere with cell growth.
3. The document provides classifications of chemotherapy drugs and examples within each classification, including cell cycle specific and non-specific agents.
This document summarizes various classes and subclasses of cancer chemotherapy drugs, including their mechanisms of action, toxicities, and therapeutic uses. It discusses cell cycle-specific agents like alkylating agents, antimetabolites, plant alkaloids, and hormones. Alkylating agents like cyclophosphamide can alkylate DNA. Antimetabolites like methotrexate and 5-fluorouracil interfere with DNA synthesis. Plant alkaloids including vinca alkaloids and taxanes affect microtubules. Hormonal therapies include tamoxifen, aromatase inhibitors, and gonadotropin-releasing hormone agonists. The document provides detailed information on numerous chemotherapy drugs.
CANCER: A group of disease involving abnormal cell growth with the potential to invade or spread to other part of the body.
CHEMOTHERAPY: the term chemotherapy is describe as the use of chemicals or drugs to treat cancer.
CYTOTOXIC DRUG: lysis both normal and cancer cells
Antineoplastic agents can be classified as cytotoxic drugs, hormones, or miscellaneous agents. Cytotoxic drugs include alkylating agents, antimetabolites, plant derivatives, and antibiotics. They work by directly damaging DNA or interfering with cell division and metabolism. Combination therapy is more effective than single agents to increase response rates and decrease resistance development.
The document discusses principles of chemotherapy including stages of mitosis, classification of cytotoxic agents, their action sites in the cell cycle and at the cellular level, metabolism and resistance mechanisms of cyclophosphamide as an example, and combination therapy aims to increase efficacy while managing side effects.
The document discusses various types of antineoplastic agents (anticancer drugs) that are used to treat cancer. It describes how the drugs work, their classifications, mechanisms of action, examples of drugs within each class, dosages and side effects. The classes discussed include alkylating agents, antimetabolites, vinka alkaloids, taxanes, epipodophyllotoxins, antibiotics, and miscellaneous cytotoxic drugs.
ANTI CANCER DRUGS[ANTI-NEOPLASTIC DRUGS] MEDICINAL CHEMISTRY BY P. RAVISANKAR.Dr. Ravi Sankar
The document discusses antineoplastic agents (anticancer drugs) and provides information on cancer and its diagnosis and treatment. It defines cancer as uncontrolled cell growth and discusses how cancer is classified. It also summarizes some common cancer types in children and adults. The document outlines several methods used to treat cancer, including surgery, radiation therapy, immunotherapy, hormonal therapy, chemotherapy and antibiotics. It provides classifications of antineoplastic drugs and examples.
The document categorizes and describes various classes of drugs used in cancer chemotherapy, including their mechanisms of action, pharmacokinetics, adverse effects, and clinical uses. It discusses cytotoxic drugs that act directly on cells like alkylating agents, antimetabolites, vinca alkaloids, taxanes, and antibiotics. It also covers drugs that alter the hormonal milieu and miscellaneous drugs like hydroxyurea. For each class, it provides one or more examples and describes in detail the example drug's mechanism, pharmacokinetics, adverse effects and clinical applications.
This document provides information about a special issue of the International Journal of Cancer Studies & Research focused on chemotherapy and radiology. The issue will include original research articles, short communications, mini-reviews, and reviews covering topics like drug design, cancer therapeutic development approaches, chemotherapy, radiotherapy, telomerase, telomeres, anticancer therapeutics, pathway databases, EGFR signaling, and the Warburg effect. The guest editors are Juong G. Rhee from the University of Maryland and Praveen Kandi from ScieGen Pharmaceuticals Inc. Authors are invited to submit work reviewing all aspects of chemotherapy and radiation therapy, including pathogenesis, diagnosis, treatment, and infection control with anticancer drugs.
One way to alleviate the terrible side effects of chemotherapy is to find a way to better control what cells are needed
to be targeted by the drugs in cancer patients. By being able to target on ly the cancerous cells within the body, less
chemotherapy drugs would need to be injected into the patient for cancer treatment, thus reducing, if not completely
wiping away, the side effects of the chemotherapy drugs. Cancer researchers have figured out a method that better
delivers drugs, such as chemotherapy drugs, to cancer cells without damaging surrounding healthy ones, by
discovering a way to use single-walled carbon nanotubes (SWCNTs) as targeted medicinal delivery mediums. For
how small they are, their inner volumes are relatively large, leaving enough space to carry drugs into the body. Both
the inner and outer surfaces of SWCNTs can be easily modified for “functionalization”. Their small size nature
allows them to enter the nuclei of cells freely. Most importantly, single-walled carbon nanotubes are completely safe
and nontoxic and proven to be stable to use in inserting and transporting drugs into the body. Presently, carbon
nanotubes are not only being used as drug delivery systems, but as a means of directly killing malignant cells within
the body. All of these applications of CNTs makes it promising and would lead to great advances in medicine in the
future.
Annual advances in traditional medicine for tumor therapy in 2019LucyPi1
Abstract Today, the treatment of tumors remains a difficult problem. Traditional medicine has been used to treat cancer in different countries worldwide. However, while traditional medicine is popular globally, it is not yet accepted by Western medicine as some of the ingredients and the mechanism of action for the therapeutic effect have not been fully elucidated. Thus, scholars studying traditional medicine in the treatment of cancer have strived to solve this problem. In this review, we summarized the research progress of several traditional medicines used as tumor therapies in 2019 from the PubMed database. Studies of tumors treated with traditional Chinese medicine (TCM) are popular worldwide and obtain the most attention, which attracts more researchers to this field. The anti-tumor effects of Chinese herbal medicine-derived phytochemicals, such as polyphenols, polysaccharides, saponins, and alkaloids were the new research targets for 2019. The anti-tumor effects of TCM formula such as Sijunzi decoction, and Xiaopi formula have attracted the most attention in the past year. In addition to TCM, we also focused on the anti-tumor studies of other traditional medicines, including Thai traditional medicine, traditional medicine in Sri Lanka, traditional African medicine, traditional Korean medicine, and traditional Japanese medicine.
The document provides the curriculum vitae of Prof. Dr. Loutfy H. Madkour, including his educational background, professional experience, publications, awards, and editorial roles. It notes that he is a Professor of Physical Chemistry and Nanoscience in Egypt with over 200 peer-reviewed publications. It also lists the many international journals that he serves as an editorial board member for in the fields of physical chemistry, nanoscience, and pharmaceuticals.
How to Understand and Treat Cancer with Modern Methods. Public Presentation B...Sheldon Stein
Professor Serge Jurasunas' Public Presentation on the New Modern Way to Treat Cancer - Strategic Immunotherapy, Apoptosis, Angiogenesis at the Biobran Workshop in Zagreb, Croatia, 2-27-2018.
TOFIQ Journal of Medical Sciences (TJMS) is published by TOFIQ: an NGO registered at the
State of Maryland as a non-profit organization dedicated to helping Iraq Higher Education and
Research.
TJMS is devoted to the publication of original research, commentaries on a current topic,
reviews, letters to the editor, and editorials in the field of medical sciences. The early focus of the
journal is on clinical burden of disease in Iraq: documentation of its nature and extent; clinical
patterns and epidemiology; diagnostic findings; and therapeutic strategies. Read more ...
Focus and Scope
TOFIQ Journal of Medical Sciences (TJMS) is published by TOFIQ: an NGO registered at the
State of Maryland as a non-profit organization dedicated to helping Iraq Higher Education and
Research.
TJMS is devoted to the publication of original research, commentaries on a current topic,
reviews, letters to the editor, and editorials in the field of medical sciences. The early focus of the
journal is on clinical burden of disease in Iraq: documentation of its nature and extent; clinical
patterns and epidemiology; diagnostic findings; and therapeutic strategies.
TOFIQ Journal of Medical Sciences (TJMS) is published by TOFIQ: an NGO registered at the
State of Maryland as a non-profit organization dedicated to helping Iraq Higher Education and
Research.
Dissertation topics on cellular basics of cancer and therapeutics - PubricaPubrica
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This document provides biographical and professional details about Prof. Dr. Loutfy H. Madkour. It summarizes that he is a Professor of Physical Chemistry and Nanoscience in Egypt who has published over 200 research papers and 8 books. He serves on the editorial boards of numerous international journals in physical chemistry, nanoscience, and related fields. His research interests include electrochemistry, corrosion science, nanotechnology, and environmental chemistry.
SOCIAL AND ECONOMIC BURDEN OF CANCER ON 2020- REVIEW Tamizhazhagan, Pugazh...Earthjournal Publisher
SOCIAL AND ECONOMIC BURDEN OF CANCER ON 2020- REVIEW
Tamizhazhagan, Pugazhendy, Sakthidasan, Jayanthi, Ki-Hyun Kim
IRO INTERNATIONAL JOURNAL OF MEDICAL AND APPLIED SCIENCES 2018, 1(1):24-30.
This document summarizes the results and recommendations from the 2009 Consensus Conference on antiemetics organized by ESMO and MASCC. The conference updated guidelines for preventing chemotherapy- and radiotherapy-induced nausea and vomiting. Key points:
- Chemotherapy agents were classified into four levels of emetogenic potential (high, moderate, low, minimal) based on literature review. This classification guides antiemetic treatment recommendations.
- For prevention of acute nausea/vomiting from highly emetogenic chemo like cisplatin, the addition of the NK1 receptor antagonist aprepitant to ondansetron and dexamethasone was found to significantly improve complete response rates compared to the standard regimen.
The document is a program of events for the University of Illinois at Urbana-Champaign Innovation & Start-Up Showcase on October 8, 2015. It includes a schedule of faculty presentations on their research and related start-up companies, as well as sessions on poster presentations and start-up pitches. Some of the faculty presentations will cover developing new cancer therapeutics through natural products, targeted drug delivery, and T-cell therapies.
Tofiq journal of medical sciences vol 3, issue 2 (2016)مجلة توفيق الطبيةTaghreed Al-Noor
TOFIQ Journal of Medical Sciences (TJMS) is published by TOFIQ: an NGO registered at the State of Maryland as a non-profit organization dedicated to helping Iraq Higher Education and Research. TJMS is devoted to the publication of original research, commentaries on a current topic, reviews, letters to the editor, and editorials in the field of medical sciences. The early focus of the journal is on clinical burden of disease in Iraq: documentation of its nature and extent; clinical patterns and epidemiology; diagnostic findings; and therapeutic strategies
This document summarizes the development of a nebivolol hydrochloride-loaded nanostructured lipid carrier (NEB-NLC) hydrogel for transdermal drug delivery. Key points:
1. NEB-NLCs were prepared using different lipid/surfactant combinations and the optimized formula was selected based on particle size, entrapment efficiency, and in vitro release.
2. The optimized NEB-NLCs formula was incorporated into carbopol 934 hydrogel base. Characterization of the NEB-NLC hydrogel found a particle size of 228 nm, zeta potential of -29mV, viscosity of 7210cps, and drug content of 95%.
Glucose Metabolism in Cancer The Warburg Effect and Beyond.pdfBkesNar
This document provides an overview of cancer statistics and treatment options. It notes that cancer is now the leading cause of death worldwide. While improvements have been made in high-income countries, survival rates remain low in low-income countries due to inadequate diagnosis and treatment. The document discusses some steps that can be taken to improve cancer outcomes globally, including controlling risk factors, improving screening and treatment, and implementing effective and affordable management interventions. It also reviews current standard cancer treatment options and newer approaches like targeted therapy and precision medicine.
This document summarizes a presentation on biosimilars given in Europe. It discusses:
- The new drug development paradigm for biosimilars based on comparability rather than traditional clinical trials.
- Differences in biosimilar definitions and regulations across European countries.
- The importance of national regulators' opinions in influencing biosimilar acceptance.
- Efforts to close the information gap between regulators, manufacturers, and healthcare professionals regarding biosimilars.
- Strategies to build trust in biosimilars among stakeholders like educating prescribers and involving patient organizations.
The document discusses the importance of the pharmaceutical industry to Europe. It summarizes that the industry directly employs over 630,000 people in Europe and contributes 3.5% of EU manufacturing value. It is one of the few remaining high-technology industries in Europe. The industry also plays a dual role as a major economic contributor and in improving health outcomes for European citizens. However, access to new medicines remains a challenge due to the high costs of research and regulatory hurdles.
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International Journal of Cancer Studies & Research (IJCR) ISSN:2167-9118 is a comprehensive, peer reviewed journal devoted to cancer studies and research. IJCR, published by SciDoc is an open access journal that includes high quality papers, which covers all major areas of Cancer and its related fields. SciDoc with its Open Access publication model spreads all the day-to-day developments and research to readers around the world.
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Syllabus
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Introduction to objective, scope and outcome the subject
Chapter 2
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Chapter 3
Surveying: Object Principles & Types of Surveying; Site Plans, Plans & Maps; Scales & Unit of different Measurements.
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Chapter 4
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Chapter 5
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Chapter 6
Environmental Engineering: Environmental Pollution, Environmental Acts and Regulations, Functional Concepts of Ecology, Basics of Species, Biodiversity, Ecosystem, Hydrological Cycle; Chemical Cycles: Carbon, Nitrogen & Phosphorus; Energy Flow in Ecosystems.
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2. Satheesh Gopi, Basic Civil Engineering, Pearson Publishers.
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OMICS Publishing Group | Chemotherapy
1.
2. OPEN ACCESS: BENEFITS
Benefits to researchers, institutions, nations
& Society as whole.
For researchers, increased visibility raising
impact factor.
Benefit for researchers who can’t pay for
paper subscription.
As in today’s era of internet its free to access
research articles on related latest researches
to researchers & Scholars.
4. Chemotherapy deals with the study &
treatment of diseases using chemical
agents/drugs, that are selectively toxic to the
causative agent of the disease.
5. Make the research work freely accessible
globally through internet to share the
innovations of the researchers to scientific
community.
Chemotherapy aims to provide current
events, advantages and limitations in the
field of chemotherapy.
6. Chemotherapy: Open Access consists of
43 well qualified EB members throughout the
world mostly from USA, Japan, UK and some
other countries
7. EB MEMBER CATEGORISATION
Percentage
Others Cancer
15% Chemotherapy
Target for 17%
Chemotherapy Chemotherape
15% utic Agents
17%
Immunochemot
herapy Chemotherapy
14% Drugs
Chemotherapy:
12%
Treatment &
Side effects
10%
8. JOURNAL STATUS
Startedin 2011
Released first issue in March 2012
Recently Released Vol. 2, Issue 3
Releasing Vol 3, Issue 1 in Feb 2013
9. JOURNAL STATUS
30
29.5
No of Articles
29
28.5
28
27.5
27
Recieved Accepted Published
No. Of Articles 30 29 28
10. FUNDING ARTICLES
1 article funded by Japan Society for the
Promotion of Science and Smoking
Research Foundation.
Above 90% from high income country
11. Journal of Cancer Science & Therapy
Journal of Carcinogenesis & Mutagenesis
JCST started in 2009, Currently Vol 5, Issue 2
JCM started in 2010, Currently Vol. 3,Issue 2
12. RELATED JOURNALS FROM OTHER SOURCE
Journal of Chemotherapy (Maney Publishing)
Journal of Infection and Chemotherapy
(Springer)
Journal of chemotherapy (ResearchGate)
Journal of Antimicrobial Chemotherapy
(Oxford Journals)
International Journal Of Experimental &
Clinical Chemotherapy (Karger)
13. Two Special Issues has been approved for
Chemotherapy
Translational Pathology
Immunochemotherapy
14. RELATED CONFERENCES
Optimizing Outcomes in Colorectal Cancer Boston, United States of
America, 7th Feb 2013.
CHI's Targeting Cancer Stem Cells San Francisco, United States of
America, 11th Feb 2013.
16thScripps Cancer Center's 33rd Annual Clinical Hematology and
Oncology Conference San Diego, United States of America, 16th Feb
2013.
2nd Novel Cancer Therapeutics Summit Las Vegas, United States of
America, 25th Feb 2013.
24th Annual Cancer Progress Conference New York, United States
of America, 5th March 2013
15. 7th Conference on Experimental and Translational Oncology -
CETO Portoroz, Slovenia, 20th April 2013.
British Gynaecological Cancer Society Annual Scientific
Meeting Belfast , Ireland, 20th June 2013.
MASCC/ISOO 2013 International Cancer Care
Symposium Berlin, Germany, 27th June 2013.
27th17th ECCO - 38th ESMO - 32nd ESTRO European Cancer
Congress Amsterdam, Netherlands, 27th Sep 2013.
16. TO ADVERTISE THE JOURNAL AT CONFERENCES
Firstly advertise on the conference
website by placing banner ads with a
link to our website.
At the conference venue placing our
banners
Make use of pamphlets, Journal Digital
file to explain about our journals scope.
Inviting researchers attending related
conference by invitation letter and
17. INDEXING
It shows our table of content and abstracts
included in various online collections.
It increases visibility of our journal & perceived
quality of our journal.
It increases the ability to be searched for
information among various other publications.
18. INDEXING OF THE JOURNAL
Chemotherapy is indexed in
Google Scholar
OARE
Open J-Gate
DOAJ
COPERNICUS
SCRIUS
19. PLAN FOR INDEXING IN SCOPUS,MEDLINE,ISI
Issue release at regular interval.
Send invitations to quality person having
relevant field of interest as per the journal.
Coin special issue topics on recent ongoing
researches.
Updates EB profile every month based on
their designation, research interest etc.
Provide variable fee for different countries.
20. Gentle and polite communication in a
professional way with the researchers.
Form your own words at different situations
or for replies instead of same type of
communication to gain interest from
contributors.
Regular communication with EB members
and researchers for their suggestions and
contributors.
21. Updating status of EB member in website
regarding their designation, research
interest and ongoing projects, thus by
communicating regularly to gain interest
from them.
Accepting quality paper regardless of
country.
Providing variable fee for different
countries.
22. CONTACT US
Articles can be submitted to
editor.cmt@omicsonline.org
or
http://omicsgroup.org/editorialtracking/chemother
apy/SubmitManuscript.php
Website:
http://www.omicsgroup.org/journals/cmthome.php