Bradley Holt gave a presentation on building offline-first mobile web apps using PouchDB, IBM Cloudant, and IBM Bluemix. He discussed how ubiquitous connectivity drives the need for offline capabilities due to unreliable networks. PouchDB allows creating and syncing databases locally on devices. Data can be synced bidirectionally between PouchDB and Cloudant. Hybrid mobile apps can be built with tools like Cordova, PhoneGap, and Ionic. The presentation provided code examples for key PouchDB functions like creating, querying, and replicating databases.