This document provides information on nutrition and balanced diets. It defines key terms like nutrition, diet, and nutrients. It describes the classification of foods by origin, chemical composition, predominant function, and nutritive value. The major nutrients of proteins, fats, carbohydrates, vitamins, and minerals are explained. A balanced diet is outlined as one containing different types of foods in adequate quantities and proportions to meet energy and nutrient needs. Recommended dietary allowances and nutritional assessment methods are also summarized.”
Dental Plaque
Soft deposits that form the biofilm adhering to the tooth surface or other hard surfaces in the oral cavity, including removable & fixed restorations”
Bowen , 1976
Bacterial aggregations on the teeth or other solid oral structures
Lindhe, 2003
Its a presentation on nutrition and oral health , one of the most important unit in Community dentistry. I hope this ppt will help those who want to gain knowledge on this topic. I thank those people in advance who are going to put trust in me and my work.
Dental Plaque
Soft deposits that form the biofilm adhering to the tooth surface or other hard surfaces in the oral cavity, including removable & fixed restorations”
Bowen , 1976
Bacterial aggregations on the teeth or other solid oral structures
Lindhe, 2003
Its a presentation on nutrition and oral health , one of the most important unit in Community dentistry. I hope this ppt will help those who want to gain knowledge on this topic. I thank those people in advance who are going to put trust in me and my work.
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Relationship between the type of food, frequency of intake and various cariogenic and non-cariogenic factors which influence initiation and progression of caries have been studied over the years.
Diet and dental caries /orthodontic courses by Indian dental academy Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.
Nutrition is very important for a growing child as it not only effects the general health but also the oral health, which are ultimately interrelated. This presentation will help you to understand Nutrition as a Pediatric Dentist.
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Relationship between the type of food, frequency of intake and various cariogenic and non-cariogenic factors which influence initiation and progression of caries have been studied over the years.
Diet and dental caries /orthodontic courses by Indian dental academy Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.
Nutrition is very important for a growing child as it not only effects the general health but also the oral health, which are ultimately interrelated. This presentation will help you to understand Nutrition as a Pediatric Dentist.
balanced diet preventions and treatments. malnutrion and associatedd conditions. importaance of maintainind ideal ffood habits etc. discussed under gwhere
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Food and nutrition are providing energy to our bodies in a way that we get fueled through ingestion. One way of being a responsible human being is knowing more information about them. As a result, this presentation is created to help you achieve that.
We live in an era of technologic advancements. Dentistry is no behind in this era. Here is a brief sum up of teledentistry and its applications in the field.
A very important aspect in determining and studying disease is the knowledge of surveys. Its designs, methods etc. This elaborative presentation gives a detailed insight to the survey procedures used in dentistry. Special section on the WHO oral assessment proforma.
So what is public health dentistry, why is it important to be included in the dental curriculum. Its here in this presentation. Go through it to get a small tour into public health dentistry.
Major reason for failures in the field of medicine is infections. So its a prime duty to know and follow the protocols to infection control, in the dental field as well.
First aid/disaster management & dentistryDocdhingra
As a dentist, we have so many roles. And one of the responsibilities comes to play in the scene of disasters. Here is a presentation - a small guide tool to the same.
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
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Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
2. LEARNING OBJECTIVES
• Definitions
• Classification of foods and nutrients
• Balanced diet
• Know about various nutrients and their RDA
• Other Aspects of nutrition.
3. Nutrition :
The Science Of Food And Nutrients, Their Action And
Interaction For Health And Disease, And The Ways By
Which The Organs Ingest, Digest And Excrete.
DEFINITION…
Diet :
The Sun Total Of Food Taken By An Individual.
Nutrients :
The Substances That Enable Cells And Tissues To Carry
Out Vital Functions.
4. BY ORIGIN
CLASSIFICATION OF FOODS
BY CHEMICAL
COMPOSITION
BY PREDOMINANT
FUNCTION
BY NUTRITIVE VALUE
1.Animal Food
2.Vegetable Food
Proteins, Fats, Carbohydrates,
Vitamins, Minerals
1.Body building foods : PROTEINS
2.Energy giving foods:
CARBOHYDRATES/FATS
3. Protective foods : VITAMINS &
MINERALS
1.Cereals & millets
2.Pulses
3.Vegetables
4.Nuts and oilseeds
5.fruits
6.Animal foods
7.Sugar and jaggery
8.Fats and oils
9.Condiments and spices
10.Misc.
6. ONE WHICH CONTAINS DIFFERENT T YPES OF FOODS IN SUCH
QUANTITIES AND PROPORTIONS THAT THE ENERGY, AMINO ACIDS,
VITAMINS, MINERALS IS ADEQUATELY MET FOR MAINTAINING
HEALTH, VITALIT Y AND GENERAL WELL BEING.
IT ALSO MAKES PROVISION FOR EXTRA NUTRIENTS REQUIRED
DURING DIFFICULT PERIODS.
BALANCED DIET
THERE IS NO SINGLE FOOD THAT CONTAINS ALL THE NUTRIENTS.
The Recommended Dietary Allowances (RDA) is a guideline for
the nutrient intake setup by the Food and Nutrition Board.
- RDA is the recommendation for the average daily amounts of
nutrients which should be consumed over a period of time.
7.
8. “The FOOD GUIDE PYRAMID” : a nutritional education guide
emphasizes foods from the five major food groups shown in lower 3
sections of pyramid.
12. BASAL METABOLIC RATE (BMR)
NUTRITIONAL ASSESSMENT
The amount of energy expended while at rest in neutral temperature
environment, in past absorptive state (meaning that digestive
system is inactive, which requires 12hrs. of fasting in humans).
13. PROTEINS
Chief Body building foods.
Formed from smaller
components - Amino Acids.
AA : 20 in number
• Essential AA
• Non-Essential AA
Classified :
1. Animal proteins - eggs,
meat, milk.
2. Vegetable proteins - pulses,
cereals, nuts, beans etc.
Functions :
1. body growth and maintenance
2. precursors of important
compounds
3. maintain fluid balance
4. important role in nutrient
transport
15. ASSESSMENT OF PROTEIN NUTRITION STATUS
▪ Protein nutrition status is measured by
Serum Albumin Concentration.
▪ It should be more than 3.5 g/dl.
▪ Less than 3.5 g/dl shows mild malnutrition.
▪ Less than 3.0 g/dl shows severe
malnutrition.
Kwashiorkor : protein
deficiency during 1-5 years.
Marasmus : protein deficiency
in infancy (0-1 year).
16. FATS
- A concentrated source of energy.
- Supplies double the energy furnished by either
proteins or carbohydrates.
THE MOST IMPORTANT ESSENTIAL FATTY ACID IS LINOLEIC ACID.
17.
18. A total of 40-60gm of fat can be consumed daily, so that it
contributes to 15-20% of the calories in diet.
RDA for reference man and woman : 20gm/day.
19. CARBOHYDRATES
- The main component of food.
- Main source of energy. (1gm = 4Kcal)
- Provide 85-90% of energy.
- Carbohydrate reserve of human adult is 500gm.
23. MINERALS & TRACE ELEMENTS
Inorganic substances required by the body.
Elements, whose daily requirements is more than 1.0mg are grouped
as minerals. (Ca, Ph, Fe)
Other elements required in traces (Co, Cu, Mn)
24. WATER
• Important constituent of diet- comprising both intra and
extracellular component of the body.
• Constitutes 2/3rd of human body.
• A normal man of approx. 65kg contains 40 liters of water.
The total fluid intake
requirement is:
1200ml for 1 year olds.
1500ml for 5 year olds.
>3000ml per day for adults.
Water depletion: dehydration,
mental confusion, vertigo, skin
becomes doughy, RBF reduced.
26. FOOD FORTIFICATION
The process whereby nutrients are added to foods to improve
the quality of food.
Eg : Common salt (NaCl) is fortified with Iodine.
Vanaspati ghee is deficient in Vit. A &D (as compared to animal
fat.), so it is fortified with Vit. A & D.
FOOD ADULTERATION
The process of mixing, substituting, concealing, putting up of
decomposed foods for sale, misbranding or giving false labels.
Eg:
Mixing water with milk.
Non-permitted colors used by sweet makers
Green dye used in green peas packing.
28. LEARNING OBJECTIVES
• Carbohydrates and related diseases
• Fats and related diseases
• Proteins and related diseases
• Vitamins and related diseases
• Trace elements and related diseases
29. CARBOHYDRATES
SYSTEMIC DISEASES
• Obesity
• Diabetes
• Cardiovascular diseases
• Glycogen storage disease
• Fructosuria, Galactosemia
• Pentosuria
ORAL DISEASES
• Increased incidence of
caries and periodontal
diseases
• Refined carbohydrates :
decalcification of
enamel and dentin.
30. If ingested in excess, will be deposited in adipose tissue.
ATHEROSCLEROSIS : cholesterol in arterial walls - CHD
(LDL, VLDL: harmful, HDL: protective.)
OBESITY leading to DM, Arterial HTN, etc.
PHRENODERMA : rough n dry skin- “toad skin”. (Kerala,
Karnataka, Gujarat)
CANCER : increased risk of colon and breast cancer.
Fat free diet produces essential fatty acid deficiency.
FATS
WHO/FAO expert group: total fat 15-30% energy is
consistent with good health.
31. Protein deficiency usually occurs at age of 1-5
yrs.
Early weaning and poor SES are common
causes.
MARASMUS : (0-1 yr)
• wasting, nearly complete loss of body fat.
• retarded development
• mental changes
• changed texture of hair
• frequent diarrhoea
KWASHIORKAR : (1-5 yr)
• hypoalbuminemia
• edematous fatty liver
• dermatosis (skin shows diffused pigmentation)
• GI disturbances, poor appetite
• psychic changes
• sparse and silky hair (Flag sign)
PROTEINS
32. Protein deficiency in adults usually seen in
hospitalized patients :
Chronic alcoholics and other drugs addicts as they
have irregular food habits.
Patients suffering from GI disorders as they may not be
able to eat, digest and absorb protein.
Surgical patients with sever injuries, burns have
increased nitrogen loss and are unable to feed normally.
Chronic renal disease: patients lose large amount of
protein through urine.
Hepatic disease: patients are unable to synthesize
proteins from amino acids.
33. SYSTEMIC DISEASES :
Eyes- Xerosis (dryness), Keratomalacia (softness of cornea), Corneal Opacities,
Night blindness.
Skin- dry and rough with hyperkeratinization, atrophy of sweat glands.
Respiratory Tract- keratinization of bronchopulmonary epithelium - increased
susceptibility to infection.
GIT - unhealthy GI mucosa - recurrent diarrhea
Urinary Tract- increased tendency to urinary stone formation.
Reproductive system- sterility due to faulty spermatogenesis.
Growth Retardation
Immune deficiency
VITAMINS
VITAMIN A (Beta Carotene)
HYPOVITAMINOSIS A
HYPERVITAMINOSIS A
ACUTE: headache, drowsiness, irritability, rise in intracranial tension,
vomiting, liver enlargement, shedding of skin.
CHRONIC: weight loss, nausea, vomiting, dryness of mucosa of lips, bone
and joint pain, hepatomegaly.
34. ORAL DISEASES
Oral Mucosa : hyperkeratotic or follicular keratotic changes
in oral epithelium.
Gingival Epithelium : hyperplastic and hyperkeratotic.
Enamel Organ : atrophy, degeneration of odontoblasts - poor
calcification- enamel hypoplasia.
Atrophy of salivary glands- reduced salivary flow.
Cementum : irregular cemental resorption, ankylosis of
teeth.
Eruption Rate : retarded
Alveolar bone: atrophy in severe cases
HYPOVITAMINOSIS A
HYPERVITAMINOSIS A
ORAL DISEASES
Mesenchymal tissues are highly sensitive. Rate of resorption
of alveolar bone is reduced, as a result the bone becomes
abnormally thin.
35. VITAMIN D D1
D2 : Calciferol
D3 : CholecalciferolDEFICIENCY
RICKETS in children. OSTEOMALACIA in adults.
RICKETS
• Overgrowth of epiphyseal cartilage.
• Persistence of distorted, irregular masses of cartilage.
• Deposition o osteoid matrix in inadequately mineralized
cartilaginous remnants.
• Disruption of orderly placement of cartilage by osteoid matrix.
• Deformation due to loss of structural rigidity of developing bones.
OSTEOMALACIA
• Contours of bones are not affected.
• Bone is weak and vulnerable to
gross fractures.
• most likely affected- vertebral
bodies and femoral necks.
36. Oral Manifestations :
Eruption of teeth is retarded.
Enamel hypoplasia.
Osteoporosis of alveolar bone
• Reduction in width of PDL space.
• Defective calcification of cementum
• Distortion of growth pattern of alveolar bone.
37. HYPERVITAMINOSIS D
Induces a very intense calcification of bone.
Formation of renal calculi and adrenal dysfunctions.
When ingested- most toxic vitamin.
EFFECT ON TEETH AND
PERIODONTIUM
• Irregular dentin formation and pulp
stones.
• Alveolar bone, Periodontal
membrane and gingiva become
hypercalcified. Cementum deposition
increases excessively leading to
ankylosis.
• Excessive amount of calculus.
• Rampant caries, thinning of enamel,
dentin and alveolar process.
•Pulpal calcification.
38. DEFICIENCY
Nervous System : Anatomic changes in nervous system.
Clinical manifestations depend upon severity and extent of
lesions. Most consistent- Depressed tendon reflexes,
Ataxia, Dysarthria, Loss of pain sensation.
Blood : Hemolytic and hypoplastic anemia.
Mesenchymal Tissues : Degenerative lesions in skeletal
muscles and heart.
VITAMIN E (Alpha Tocopherol)
HYPERVITAMINOSIS E
Least toxic vitamin.
Hypervitaminosis has yet not been
described.
39. DEFICIENCY
Development of a bleeding diathesis characterized
by hematomas, hematuria, malena and ecchymoses.
In neonates, most serious manifestation is
intracranial hemorrhage. Bleeding may occur at any
site, including skin, umbilicus, viscera.
VITAMIN K K1 (Phytodione)
K2 (Menadione)
ORAL DISEASES
Gingival bleeding (most common)
Prothrombin levels <35% -
Bleeding during brushing.
Prothrombin levels <20% -
spontaneous gingival hemorrhage.
40. Mainly hits the peripheral
nerves, brain and heart.
Beri Beri
VITAMIN B1 (Thiamine)
DEFICIENCY
Dry Beri Beri
(poluneuropathy)
Non specific peripheral neuropathy
with myelin degeneration and
disruption of axons, involving motor,
sensory and reflex arcs.
Wet Beri Beri
It leads to peripheral
vasodilation,
subsequently more rapid
AV shunting of blood.
Peripheral edema.
Wernicke-Korsakoff Syndrome
It is mostly encountered in chronic alcoholics.
Opthalmoplegia, Nystagmus, ataxia of gait,
derangement of mental function characterized
by confusion, restlessness, disorientation.
41. No specific lesions.
Hypersensitivity of oral mucosa seen.
Oral and facial neuralgias and pain, herpes simplex,
aphthous stomatitis can be treated by thiamine.
Edematous swelling of gingiva and lingual papillae
and taste impairment may be seen.
Oral Diseases
HYPERVITAMINOSIS
Thiamine is non toxic when taken by mouth.
Parenteral administration causes anaphylactic
shock in H/S individuals.
Contact dermatitis in patients allergic to thiamine.
42. DEFICIENCY
Ariboflavinosis : in economically deprived and developing countries.
Angular stomatitis, cheilosis, nasolabial seborrhoea.
Eyes : circumcorneal vascularization. accompanied by lacrimation
and photophobia.
Skin : fine scaly dermatitis on hands, vulva, anus, perineum.
VITAMIN B2 (Riboflavin)
On Lips : Cheilosis and angular stomatitis. Chronic lesions may develop a
yellow crust. Dryness and slight burning sensation. Both angles are equally
involved.
On Tongue : Lingual papillae are inflamed, flattened and mushroom shaped,
giving the dorsum a granular appearance.
Tongue may turn purplish red or magenta due to dilation and proliferation of
capillaries. Painful and sensitive to food.
Oral Diseases
43. DEFICIENCY
Dermatitis : usually bilaterally symmetrical, found on exposed areas of
body.
Diarrhoea : Caused by atrophy of columnar epithelium of GI tract.
Dementia : Due to degeneration of brain accompanied by degeneration of
corresponding tracts of spinal cord.
VITAMIN B3 (Niacin/Nicotinic Acid)
Now fourth D : Death also added as disease is fatal if not treated.
PELLAGRA
(three D’s)
HYPERVITAMINOSIS
Due to its action as a vasodilator.
Reddening and flushing of skin, increased skin temperature,
dizziness, headache, nausea, vomiting, abdominal pain.
44. Oral Diseases
•
• Oral Mucosa : entire oral mucosa becomes red and painful.
• Tongue : desquamation of epithelium, leaving a scarlet, smooth,
dry, beefy tongue. Swelling of tongue with indentations on the
margins. Extremely painful and sensitive to food and drinks.
• Gingiva : Tenderness, pain, redness, ulcerations begin at
interdental papillae and spread rapidly. Salivation becomes
excessive, diminished taste sensation. Superimposed ANUG is
common.
• Dental Caries : Incidence of caries is reduced in niacin deficiency.
May be because Nicotinic acid is an essential growth factor for
oral microflora.
45. VITAMIN B4 (Adenine)
Synthesized by human body.
Does not have much nutritional value.
VITAMIN B5 (Pantothenic Acid)
Deficiency is rare;
Burning feet syndrome
No oral manifestations.
Curative value in treatment of Glossitis
and Cheilitis
46. VITAMIN B6 (Pyridoxin)
DEFICIENCY
Rare similar to riboflavin and niacin deficiency.
ORAL MANIFESTATIONS:
- On lips : bilateral angular cheilosis.
- On tongue : glossitis with slight pain, edema, papillary
atrophy, purple blue.
- Glossitis begins as scalding sensation of tongue followed
by redness and hypertrophy of filiform papillae.
- Dental Caries : increased incidence of caries as it alters
oral microflora to more cariogenic organisms.
47. VITAMIN B9 (Folic Acid)/Vitamin M
DEFICIENCY
SYSTEMIC MANIFESTATIONS:
Macrocytic Anemia associated with megaloblastic erythropoiesis.
Glossitis, stomatitis, diarrhoea.
Steatorrhoea- foul smelling, copious, greasy appearing, light, liquid-
semiliquid stools.
ORAL MANIFESTATIONS:
- Tongue : glossitis, seen as swelling and redness along tip and margins.
- Minute, whitish aphthous ulcers with fiery red borders may emerge.
- Filiform papillae are first to disappear, the fungiform papillae remaining
as prominent spots.
- Lips : stomatitis, cheilitis, cheilosis with ulcerative lesions.
48. VITAMIN B12 (Cyanocobalamin)
DEFICIENCY
SYSTEMIC MANIFESTATONS
- Pernicious Anemia
Weakness, glossitis, numbness and tingling of extremities. It may
lead to severe psychosis.
- Macrocytic anemia and homocysteinuria
ORAL MANIFESTATONS-
- On tongue : recurrent attacks of sore tongue. Tongue becomes
fiery red and painful.
- On Lips : Chelosis, chelitis, painful mucous membranes affecting
buccal mucosa, pharynx, and gingiva.
49. VITAMIN C (L-ascorbic acid)
DEFICIENCY
SCURVY
- Hemorrhages.
- Defect in collagen synthesis resulting in purpura and
ecchymosis in skin.
- Extensive subperiosteal hematomas.
- Skeletal changes in children. : disturbances in formation of
osteoid matrix.
- Both membranous and endochondral bone formation is
affected.
- Wound healing and localisation of focal infections are impaired.
50. ORAL MANIFESTATION
GINGIVAL and PERIODONTAL TISSUES : interdental
and marginal gingiva is bright red with swollen, smooth,
shiny surfaces. Typical foul breath.
Severe forms - hemorrhages and swelling in
periodontal membranes followed by loss of bone and
loosening of teeth.
51. CALCIUM
DEFICIENCY
SYSTEMIC MANIFESTATIONS
- Rickets
- Osteomalacia
- Osteoporosis : increased porosity of bone. Seen in elderly
patients.
- Acidosis : this causes an increased excretion of calcium in urine,
leading to rarefaction of skeleton.
- Steatorrhoea : excretion of calcium in faeces.
- Hypocalcemia : may occur if too much parathyroid tissue is
removed, causing diminished mobilization of calcium from bone.
52. ORAL MANIFESTATIONS
- Effect on alveolar bone : marrow spaces become
hemorrhagic and get filled with fibro-osteoid tissue. As a
result of alveolar bone resorption, teeth become loose.
Destruction of PDL.
- Effect on teeth : when serum calcium falls as low as
6-8mg/100ml, it results in enamel hypoplasia in developing
teeth.
- Dental Caries : positive correlation between hypo plastic
enamel and dental caries incidence.
53. MAGNESIUM
DEFICIENCY
SYSTEMIC MANIFESTATIONS
Alopecia, tropic skin lesions, hematoma.
Mg interferes with protein synthesis.
Depression, hyperirritability, cardiac arrythmias, muscular
weakness and convulsions.
ORAL MANIFESTATIONS
On Enamel Organ :
predentin becomes wider, causing dentin-predentin junction to be in
different levels, leading to ‘Predentinstep’- characteristic of Mg
deficiency.
Dentin in labial portion is seriously affected. Incisal area becomes
atrophied.
On Gingival tissues : gingival hypertrophy with chronic destructive
periodontitis - loosening of teeth.
54. IRON
DEFICIENCY
SYSTEMIC MANIFESTATIONS
Hypochromic microcytic anemia.
Chronic fatigue, slightly depressed blood hemoglobin.
ORAL MANIFESTATIONS
Fissures in labial commissures, superficial glossitis.
Pappillae of tongue are atrophied - smooth, shiny and red
appearance.
Affected oral tissue becomes susceptible to oral cancer.
Tongue: ‘patchy irregular denudation of papillae’.
55. SELENIUM
DEFICIENCY
SYSTEMIC MANIFESTATIONS
Liver necrosis, degenerative changes in parenchymal
organs, muscular dystrophy, degeneration of heart muscles,
endocardial calcification and pancreatic atrophy.
Effect on DENTAL TISSUES
Low selenium conc. - Significant antibacterial effect on S.
mutans, so it decreases cariogenicity of plaque.
Combination of Se and Fluoride - effective as preventive
agent against caries.
56. MANGANESE
DEFICIENCY
Marked hypocholestrolemia, transient dermatitis,
change in color, slow growth of hair and weight loss.
IODINE
Deficiency - enlargement of thyroid gland causing
hypothyroidism, goiter, myxedema.
Iodine toxicity - thyrotoxicosis
57. COPPER
DEFICIENCY
SYSTEMIC MANIFESTATIONS
Microcytic hypochromic anemia.
Menke’s Kinkyhair Syndrome (in infants)
• severe mental deficiency
• steel hair
• long metaphyseal abnormalities
• micrognathism
• neonatal ataxia
• hypothermia
ORAL MANIFESTATIONS
Copper salts decrease plaque formation in humans, thus affecting
pathogenesis of caries.