My brief thoughts on how science funders could be poisoning the well of research creativity by over-regulating the structure of grant applications and why they are doing this.
A revolution is taking place in how science is funded: a wake up call.Jim Woodgett
As funding agencies for science around the world scramble to cope with reduced funding, increased application pressure, reviewer burdens, etc., many are making enormous changes to how they will select and adjudicate what research they will fund. The scientific community has been relatively ineffective influencing these changes yet there is little room for error and most will be impacted. This was the starting slide deck for a panel discussing research reforms at the 2013 Canadian Science Policy Conference. It is meant as a wake-up call.
Why SciComm (science communication) is a relentless storm...Jim Woodgett
The art and science of communication of science. Some ideas about how best to counter pseudoscience, quackery while recognizing the limitations of science.
Why aren’t we solving the greatest scientific problems of the world today? Innovation is critical to our nation’s scientific enterprise. However, creative thinking has been on the decline and is not generally taught in academic institutions. Renowned public health scientist and clinician, Dr. Roberta Ness, Dean of the University of Texas Health School of Public Health, believes that students, established scientists, researchers, and engineers can learn to be more innovative. Through her book Innovation Generation: How to Produce Creative and Useful Scientific Ideas, and graduate course on Innovative Thinking at the University of Texas, Dr. Ness provides the framework and tools to “think outside the box.” She shared these basic concepts in this one-hour lecture. Dr. Ness is a leading researcher in women’s health and widely known for her efforts to bridge from research to policy. She is a member of the Institute of Medicine.
97% of climate scientists agree fact or fiction_issue 1_160925Gordon Hirst
The document discusses the claim that 97% of climate scientists agree that climate change poses risks from human activities. It notes that this figure comes from a 2013 scientific study but has since taken on an almost mythical status in public debates. The author aims to provide a clear, level-headed examination of where the 97% figure came from, how accurate it is, and why it has become so divisive. The document outlines the scientific process and how science is perceived differently by experts and the public through media coverage.
Reproducibility, open access, open scienceAlex Holcombe
This document discusses issues with reproducibility and open access in scientific research. It notes studies showing that over 50% of published studies cannot be repeated, and major pharmaceutical companies could only validate around 25% of preclinical studies. It argues that the current publishing system, dominated by for-profit publishers, boxes in academic knowledge and prioritizes profits over open access. The document advocates for cultural and technological changes like open access policies, altmetrics, and software for reproducible research to help make science more open.
A revolution is taking place in how science is funded: a wake up call.Jim Woodgett
As funding agencies for science around the world scramble to cope with reduced funding, increased application pressure, reviewer burdens, etc., many are making enormous changes to how they will select and adjudicate what research they will fund. The scientific community has been relatively ineffective influencing these changes yet there is little room for error and most will be impacted. This was the starting slide deck for a panel discussing research reforms at the 2013 Canadian Science Policy Conference. It is meant as a wake-up call.
Why SciComm (science communication) is a relentless storm...Jim Woodgett
The art and science of communication of science. Some ideas about how best to counter pseudoscience, quackery while recognizing the limitations of science.
Why aren’t we solving the greatest scientific problems of the world today? Innovation is critical to our nation’s scientific enterprise. However, creative thinking has been on the decline and is not generally taught in academic institutions. Renowned public health scientist and clinician, Dr. Roberta Ness, Dean of the University of Texas Health School of Public Health, believes that students, established scientists, researchers, and engineers can learn to be more innovative. Through her book Innovation Generation: How to Produce Creative and Useful Scientific Ideas, and graduate course on Innovative Thinking at the University of Texas, Dr. Ness provides the framework and tools to “think outside the box.” She shared these basic concepts in this one-hour lecture. Dr. Ness is a leading researcher in women’s health and widely known for her efforts to bridge from research to policy. She is a member of the Institute of Medicine.
97% of climate scientists agree fact or fiction_issue 1_160925Gordon Hirst
The document discusses the claim that 97% of climate scientists agree that climate change poses risks from human activities. It notes that this figure comes from a 2013 scientific study but has since taken on an almost mythical status in public debates. The author aims to provide a clear, level-headed examination of where the 97% figure came from, how accurate it is, and why it has become so divisive. The document outlines the scientific process and how science is perceived differently by experts and the public through media coverage.
Reproducibility, open access, open scienceAlex Holcombe
This document discusses issues with reproducibility and open access in scientific research. It notes studies showing that over 50% of published studies cannot be repeated, and major pharmaceutical companies could only validate around 25% of preclinical studies. It argues that the current publishing system, dominated by for-profit publishers, boxes in academic knowledge and prioritizes profits over open access. The document advocates for cultural and technological changes like open access policies, altmetrics, and software for reproducible research to help make science more open.
Richard horton Offl ine: What is medicine’s 5 sigma?Anochi.com.
This document summarizes a symposium discussion on reproducibility and reliability issues in biomedical research. The key points are:
1) There is a widespread perception that much of the scientific literature may be untrue due to problems like small sample sizes, questionable research practices, and conflicts of interest.
2) Journals, universities, and research culture also contribute by incentivizing quantity over quality, impact factors, and "sexy" findings over important confirmations.
3) Proposed solutions discussed fixing incentives to reward reliability over productivity, preregistration, collaboration over competition, and adopting standards from fields like particle physics where the bar for a "significant" result is much higher.
4)
Fixing Science: The Replicability CrisisAlex Holcombe
This document discusses the replicability crisis in science. It notes that while textbooks teach the importance of replicating experiments, few published studies actually report replications. This allows for biases like p-hacking and publication bias to inflate false positive rates. Reasons for the replicability crisis include errors, fraud, biases in what researchers and journals choose to publish, and exploiting flexibility in analysis. Solutions proposed include conducting and publishing more replication studies, pre-registering study designs, and making data and analyses more open through initiatives like registered replication reports and open science.
The document discusses criteria for analyzing evidence and different types of evidence, including:
- Personal experience, observation, interviews, research, testimony, statistics, hypothetical examples, and reasoned sequences. It then provides examples of arguments and the evidence used in each.
The guide has brought together researchers working in some of the most significant, cutting edge fields. They told us that if policy makers and the public are discouraged by the existence of uncertainty, we miss out on important discussions about the development of new drugs, taking action to mitigate the impact of natural hazards, how to respond to the changing climate and to pandemic threats.
The guide discusses:
- The way scientists use uncertainty to express how confident they are about results.
- That uncertainty can be abused to undermine evidence or to suggest anything could be true: from alternative cancer treatments to anthropogenic CO2 not changing the atmosphere.
- Why uncertainty is not a barrier to taking action – decision makers usually look for a higher level of certainty for an operational decision (such as introducing body scanners in airports) than for a decision based on broader ideology or politics (such as reducing crime rates).
How to grapple with science advice in ideological conflictsSciAdvice14
Heather Douglas of the Institute for Science, Society and Policy at the University of Ottawa on grappling with science advice in ideological conflicts.
What is the future of scientific communication? Open Science (Claude Pirmez)http://bvsalud.org/
Apresentação da Profª Drª Claude Pirmez na Reunião de Editores Científicos do CRICS10, em 04/12/2018
http://crics10.org/eventos/pt/event/reuniao-de-editores-cientificos/
The document discusses the concept of perfect research and argues that there is always hope of doing perfect research. It provides several examples to support this argument. First, past medical research was considered perfect at the time, even though cures were not discovered yet. Second, scientific laws and discoveries like Newton's laws were based on research that was perfect for the time. Third, the author provides a personal example of accurately predicting an oil price drop based on their own research. The document concludes that research is an ongoing process, and what is considered perfect research may be modified or rejected over time as new discoveries are made.
This document outlines the lecture topics for a science journalism class. It discusses reviewing science journalism and assigned readings. It covers evaluating science blogs like PLoS, Scientopia, and Not Exactly Rocket Science. The lecture discusses the differences between science writing, communication, popularization and journalism. It also addresses knowing your audience and challenges like poor science or journalism. Students are assigned homework to read recent articles from specific science blogs.
The document provides instructions for making a sandwich including choosing bread, mayonnaise, cheese, ham, lettuce, and tomato. It lists the steps as applying mayonnaise to one slice of bread, placing cheese in the center, adding sliced ham, washing and adding lettuce leaves, slicing and adding tomato, and placing the other slice of bread on top to complete the sandwich.
This document provides biographical information about Tony Pawson and his extensive career accomplishments and collaborations. It lists Tony Pawson's many honors and awards for his scientific contributions. It also lists over 100 of Tony Pawson's trainees and over 300 collaborators he worked with over his career, demonstrating the extensive network and influence of his work.
Foot Problems are very common in people with diabetics and lead to serious complications if untreated or poorly treated so diabetic patients need to take good care of their feet.
New Investigators: starting up and keeping goingJim Woodgett
Talk at Nov 2013 New Principal Investigators meeting discussing startup negotiating, what to ask for, what others ask for, why the first 5 years of an independent position is so important and how to tease seed funding. Canadian context but applicable to many scenarios.
New York City Department of Education Individualized Education Program (IEP) sample for Kevin brown, a 16 year old student with autism (Staffing ratio: 6:1:1)
Photo slideshow for dr pawson memorial aug 21Jim Woodgett
Dr. Tony Pawson was a renowned scientist who made groundbreaking discoveries in the field of cell signaling. He uncovered how proteins interact with each other to control cell behavior through protein domains and motifs that bind specifically to one another. His work revolutionized our understanding of how signals are transmitted within cells and between cells, shedding light on processes like cell division and how diseases develop.
Global Fire Equipment is a leading player in the fire detection equipment market, providing solutions tailored to customers across 70 countries on all continents. They supply both addressable analogue and conventional fire alarm control panels and ancillary devices to airports, hotels, hospitals, education, landmarks, industry, and shopping centres.
This document provides a recipe for making perfect guacamole in 3 easy steps. The recipe calls for mashing 2 avocados with salt, lime or lemon juice, minced onion, chopped cilantro, and black pepper. The avocado mixture is lightly mashed with a fork while folding in the other ingredients to maintain a chunky texture. Finally, plastic wrap is placed directly on the surface of the guacamole to prevent browning before serving or refrigerating.
This document is a curriculum vitae for Ahmad Ali Ibrahim, a Jordanian male with qualifications including a B.Sc. in Pharmaceutical Sciences, a diploma in Pharmaceutical Sciences, and a pharmacy license from the Jordanian Ministry of Health. He has over 20 years of experience in production roles for pharmaceutical companies in Jordan, including positions as a supervisor and head of a production department, and has extensive skills in all areas of pharmaceutical production. He is seeking a job reporting to a Production Manager where he can utilize his leadership and technical skills to manage employees and ensure production targets are met.
New York City Department of Education Individualized Education Program (IEP) sample for Joseph Thompkins, an 18 year old student with Multiple Disabilities (Mental Retardation, Orthopedic Impairment) (Staffing ratio: 12:1:1)
New York City Department of Education Individualized Education Program (IEP) sample for Samantha Jackson, an 18 year old student with Mental Retardation, Other Health Impaired (Staffing ratio: 12:1:4)
Richard horton Offl ine: What is medicine’s 5 sigma?Anochi.com.
This document summarizes a symposium discussion on reproducibility and reliability issues in biomedical research. The key points are:
1) There is a widespread perception that much of the scientific literature may be untrue due to problems like small sample sizes, questionable research practices, and conflicts of interest.
2) Journals, universities, and research culture also contribute by incentivizing quantity over quality, impact factors, and "sexy" findings over important confirmations.
3) Proposed solutions discussed fixing incentives to reward reliability over productivity, preregistration, collaboration over competition, and adopting standards from fields like particle physics where the bar for a "significant" result is much higher.
4)
Fixing Science: The Replicability CrisisAlex Holcombe
This document discusses the replicability crisis in science. It notes that while textbooks teach the importance of replicating experiments, few published studies actually report replications. This allows for biases like p-hacking and publication bias to inflate false positive rates. Reasons for the replicability crisis include errors, fraud, biases in what researchers and journals choose to publish, and exploiting flexibility in analysis. Solutions proposed include conducting and publishing more replication studies, pre-registering study designs, and making data and analyses more open through initiatives like registered replication reports and open science.
The document discusses criteria for analyzing evidence and different types of evidence, including:
- Personal experience, observation, interviews, research, testimony, statistics, hypothetical examples, and reasoned sequences. It then provides examples of arguments and the evidence used in each.
The guide has brought together researchers working in some of the most significant, cutting edge fields. They told us that if policy makers and the public are discouraged by the existence of uncertainty, we miss out on important discussions about the development of new drugs, taking action to mitigate the impact of natural hazards, how to respond to the changing climate and to pandemic threats.
The guide discusses:
- The way scientists use uncertainty to express how confident they are about results.
- That uncertainty can be abused to undermine evidence or to suggest anything could be true: from alternative cancer treatments to anthropogenic CO2 not changing the atmosphere.
- Why uncertainty is not a barrier to taking action – decision makers usually look for a higher level of certainty for an operational decision (such as introducing body scanners in airports) than for a decision based on broader ideology or politics (such as reducing crime rates).
How to grapple with science advice in ideological conflictsSciAdvice14
Heather Douglas of the Institute for Science, Society and Policy at the University of Ottawa on grappling with science advice in ideological conflicts.
What is the future of scientific communication? Open Science (Claude Pirmez)http://bvsalud.org/
Apresentação da Profª Drª Claude Pirmez na Reunião de Editores Científicos do CRICS10, em 04/12/2018
http://crics10.org/eventos/pt/event/reuniao-de-editores-cientificos/
The document discusses the concept of perfect research and argues that there is always hope of doing perfect research. It provides several examples to support this argument. First, past medical research was considered perfect at the time, even though cures were not discovered yet. Second, scientific laws and discoveries like Newton's laws were based on research that was perfect for the time. Third, the author provides a personal example of accurately predicting an oil price drop based on their own research. The document concludes that research is an ongoing process, and what is considered perfect research may be modified or rejected over time as new discoveries are made.
This document outlines the lecture topics for a science journalism class. It discusses reviewing science journalism and assigned readings. It covers evaluating science blogs like PLoS, Scientopia, and Not Exactly Rocket Science. The lecture discusses the differences between science writing, communication, popularization and journalism. It also addresses knowing your audience and challenges like poor science or journalism. Students are assigned homework to read recent articles from specific science blogs.
The document provides instructions for making a sandwich including choosing bread, mayonnaise, cheese, ham, lettuce, and tomato. It lists the steps as applying mayonnaise to one slice of bread, placing cheese in the center, adding sliced ham, washing and adding lettuce leaves, slicing and adding tomato, and placing the other slice of bread on top to complete the sandwich.
This document provides biographical information about Tony Pawson and his extensive career accomplishments and collaborations. It lists Tony Pawson's many honors and awards for his scientific contributions. It also lists over 100 of Tony Pawson's trainees and over 300 collaborators he worked with over his career, demonstrating the extensive network and influence of his work.
Foot Problems are very common in people with diabetics and lead to serious complications if untreated or poorly treated so diabetic patients need to take good care of their feet.
New Investigators: starting up and keeping goingJim Woodgett
Talk at Nov 2013 New Principal Investigators meeting discussing startup negotiating, what to ask for, what others ask for, why the first 5 years of an independent position is so important and how to tease seed funding. Canadian context but applicable to many scenarios.
New York City Department of Education Individualized Education Program (IEP) sample for Kevin brown, a 16 year old student with autism (Staffing ratio: 6:1:1)
Photo slideshow for dr pawson memorial aug 21Jim Woodgett
Dr. Tony Pawson was a renowned scientist who made groundbreaking discoveries in the field of cell signaling. He uncovered how proteins interact with each other to control cell behavior through protein domains and motifs that bind specifically to one another. His work revolutionized our understanding of how signals are transmitted within cells and between cells, shedding light on processes like cell division and how diseases develop.
Global Fire Equipment is a leading player in the fire detection equipment market, providing solutions tailored to customers across 70 countries on all continents. They supply both addressable analogue and conventional fire alarm control panels and ancillary devices to airports, hotels, hospitals, education, landmarks, industry, and shopping centres.
This document provides a recipe for making perfect guacamole in 3 easy steps. The recipe calls for mashing 2 avocados with salt, lime or lemon juice, minced onion, chopped cilantro, and black pepper. The avocado mixture is lightly mashed with a fork while folding in the other ingredients to maintain a chunky texture. Finally, plastic wrap is placed directly on the surface of the guacamole to prevent browning before serving or refrigerating.
This document is a curriculum vitae for Ahmad Ali Ibrahim, a Jordanian male with qualifications including a B.Sc. in Pharmaceutical Sciences, a diploma in Pharmaceutical Sciences, and a pharmacy license from the Jordanian Ministry of Health. He has over 20 years of experience in production roles for pharmaceutical companies in Jordan, including positions as a supervisor and head of a production department, and has extensive skills in all areas of pharmaceutical production. He is seeking a job reporting to a Production Manager where he can utilize his leadership and technical skills to manage employees and ensure production targets are met.
New York City Department of Education Individualized Education Program (IEP) sample for Joseph Thompkins, an 18 year old student with Multiple Disabilities (Mental Retardation, Orthopedic Impairment) (Staffing ratio: 12:1:1)
New York City Department of Education Individualized Education Program (IEP) sample for Samantha Jackson, an 18 year old student with Mental Retardation, Other Health Impaired (Staffing ratio: 12:1:4)
Repaving the Road to Hell with the Common CV and CIHR ReformsJim Woodgett
The document discusses the history and issues with the Canadian Common CV (CCV) and CIHR reforms. It summarizes that the CCV aimed to create a shared platform for grant applications but faced problems with site reliability, usability, changing membership, and data maintenance. The CIHR reforms intended to streamline funding processes but the virtual review system and rushed implementation led to low review quality and delays. Lessons highlighted are the need for extensive user testing, flexibility, and prioritizing practical solutions over ideological frameworks during reforms.
Sabato 21 di febbraio 2015 dalle 16 alle 20.00 presso GFP Gruppo Fotografico il Ponte, via Padre Adriano Rossi, 3 – Pontenuovo di Magenta (Fronte Saffa)
Il Laboratorio ha lo scopo di creare uno spazio intimo, partecipativo ed esperienziale dove trovarsi per lavorare su di sé e per gli altri.
The document discusses several key issues regarding ethics in research:
- Research is not objective and researchers must recognize how their own biases and worldviews can influence the research process. They must actively manage power dynamics and potential biases.
- Researchers have a responsibility for the production of knowledge and must ensure accurate reporting of results, obtaining informed consent, protecting confidentiality of participants, and avoiding harm.
- Important considerations include recognizing one's own position and identity, being aware of dichotomization and power differentials, and understanding how language and cultural worldviews can impact research. Overall researchers must balance responsibilities to knowledge production with minimizing harm or abuse of participants.
Ogilvy Change is celebrating its 4th birthday after launching on a non-standard calendar date to encourage event attendance. The newsletter discusses behavioral experiments conducted by Ogilvy Change, how to effectively change minds on controversial issues, and research on how giving people the option to do nothing can increase engagement when they choose to continue with a task.
This document discusses what science is and is not. It begins by stating that science attempts to disprove ideas rather than prove them, and is concerned with understanding the natural world through observation and experimentation. It notes several misconceptions, such as the idea that science can prove anything or that there is a linear progression from hypothesis to theory to law. Good science minimizes bias through random sampling, appropriate measurement techniques, and independent verification. It emphasizes that science provides the most reliable knowledge about the natural world but does not claim certainty, only degrees of probability. Overall, the document provides a concise overview of the scientific process and addresses common misconceptions about the limitations and objectives of science.
This document outlines practical steps to improve public perception of the future in order to positively impact the future. It recommends (1) clearly seeing a set of future scenarios and thoughtfully assessing them, (2) uncovering constructive options for action, and (3) openly, vividly, and credibly communicating about the future through trends awareness, imagination, consideration of convergence, objective monitoring, experimentation, roadmapping, and collaboration. The goal is to counter short-term thinking, champion long-term responsibility, and inspire bridge-building toward desirable futures.
Understanding Attitudes to Science: Reviewing Public Attitudes ResearchMarilyn Booth
This document summarizes a review of public attitudes towards science based on previous survey research from 2000, 2005, and 2008. It discusses key findings around public understanding and awareness of science, perceptions of scientific research, trust in research findings and scientific institutions. It also provides implications for improving questions and scope in the next public attitudes survey in 2011.
This document discusses the importance of understanding the components of scientific research. It explains that exploratory research involves case studies, content analysis, and archival research. A case study is a concentrated focus on a specific topic or person, group, or entity that holds a rare quality. Case studies are used to study how things progress over time. The document also discusses that positionality, which refers to one's worldview, impacts the type of research selected and methodologies chosen. Factors like one's background, beliefs, and characteristics shape positionality and therefore influence the research process.
Experimental design aims to describe or explain how variables change under hypothesized conditions. However, it has some weaknesses and issues. It can only examine the direct impact of one or two factors rather than complex relationships. Randomization removes the effects of other variables but also removes important contextual information. There are also threats to internal validity like history effects, maturation, testing, and selection bias. External validity can be undermined if samples are not representative or conditions are artificial. Practical challenges include how much to disclose to participants, sample sizes, recruitment methods, and ensuring interventions are applied consistently. Ethical issues involve voluntary and informed consent, avoiding harm, and maintaining anonymity and confidentiality.
This lecture talks about the importance of evidence in scientific, business, and innovation research. It lists down important examples to carry this process in perspective of the problem statement.
16 Disturbing Facts that Destroy the Common Knowledge Bullsht Weve Been TaughtShanna Sloan
This document discusses 16 facts that contradict common knowledge. Some key points include:
- Keeping personal goals private increases the chances of achieving them, as announcing goals can satisfy the feeling of completion and decrease motivation.
- Self-control functions like a muscle that improves with exercise. Depleting willpower in one domain can impact other domains due to limited daily reserves.
- While passion is often seen as coming from enjoyment, research finds it is stronger when doing things one believes in rather than just enjoys.
- Unanswered callings in life are worse than having no calling, as they are detrimental to career, commitment, life satisfaction and health.
- Daydreaming can boost mood depending on content
This document discusses how social media can be used by scientists for science communication and engagement. It notes that most Americans now get news from social media and that scientists are increasingly using platforms like Twitter to discuss their research. The document provides tips for using social media effectively as a scientist, such as focusing on goals and audiences, humanizing oneself, finding the "wow" factor in science, telling stories, and communicating ethically. Scientists are encouraged to participate in two-way communication through social media to foster collaboration and increase the impact of their work.
The document discusses the Life Sciences Institute (LSI) at the University of Michigan over the past 10 years. It describes how the LSI has embraced rapid scientific changes, complexity, and financial challenges by innovating and following the science. The LSI provides a collaborative environment and infrastructure that supports basic scientific discovery and allows scientists to focus on research and publishing. It has recruited exceptional interdisciplinary faculty, built a facility conducive to collaboration, and supported students and training of the next generation of scientists. The LSI has also strengthened the university's impact globally and ties to the biotech community, resulting in patents, commercialization, and potential new drugs.
Throughout The Study Of Diseases Researchers Have DevelopedKate Subramanian
The document discusses strategies researchers have used to study and control diseases. It notes that to decrease disease occurrence, researchers must understand incidence rates and analyze new case counts. It provides polio as an example of a once-feared disease that is now preventable through immunization. The document also discusses homeostasis and how the immune system and disease states can disrupt or restore homeostasis. It describes the pathophysiological impacts of disease on body systems.
This document discusses social and biological theories behind why an HIV cure has not yet been achieved. Socially, it argues that the current competitive grant funding system creates disincentives for finding a cure due to economic interests. Biologically, it proposes several theories for a cure, including enhancing the immune response, targeting the latent HIV reservoir through "shock and kill" methods, identifying proteins that cause latent HIV to emerge, and preventing HIV replication through new drug targets. The document advocates for more collaborative, exploratory research to optimize hypotheses and find an HIV cure.
Sxsw 2013 themes: Start-up culture, code and dataMartin Bailie
Here's a short speech I delivered to the IPA 44 Club's SXSWi debate at Google HQ London last week. I talked about the themes I found prevalent at SXSWi this year: namely the importance of a start-up culture and obsession with scientific discovery for successful innovation in businesses of all sizes.
This document is a research report on female foeticide in India. It includes an introduction outlining the problem of female foeticide, a literature review of methodologies like case studies and questionnaires, and an analysis of the causes and impacts of female foeticide in India. The causes discussed include societal preferences for sons, the dowry system, and gender discrimination. Impacts mentioned are the declining child sex ratio in India and negative consequences for women. The report aims to understand reasons for female foeticide and question the effectiveness of laws in addressing the problem.
50 Free Persuasive Essay Examples (+BEST Topics) ᐅ TemplateLab. Essay websites: What is a persuasive essay. Persuasive Essay. Writing persuasive essay - The Oscillation Band. Beth Wilcox's Northern Learning Centre Blog: Persuasive Essay Format. Writing paper: Essay persuasive. An example of persuasive essay. 013 Good Persuasive Essay Topics Example ~ Thatsnotus. Essay websites: Persuasive thesis. School essay: Example for persuasive writing.
The document discusses research ethics and characteristics of ethical research. It provides examples of ethical and unethical research practices, including fabricating data, failing to publish corrections, and issues around sharing research data with other scientists. Key aspects of ethical research include objectivity, protecting research subjects, transparency in findings, and acknowledging collaborators.
This document summarizes a presentation on proposed changes to the informed consent process. The key proposed changes include shortening consent forms to only include the most relevant details, publicly posting consent documents for clinical trials, and allowing for broad consent for secondary use of biospecimens including de-identified samples. The goals of the proposed changes are to build more trust in the consent process and make it more meaningful. However, it is unclear if the changes will fully achieve these goals given challenges such as the open-ended nature of consent agreements. The presentation also discusses empirical studies conducted on community perspectives and issues regarding public health biobanks and consent.
This document discusses research misconduct and issues of reproducibility. It defines research misconduct as fabrication, falsification, or plagiarism. While science aims to be self-correcting, many published findings are not reproducible or trustworthy. Several factors make results less likely to be true, such as small studies, small effect sizes, and conflicts of interest. Efforts are underway to improve reproducibility through replicating studies, publishing negative results, and establishing standards for transparent and ethical research.
This document discusses evaluating creativity programs. It recommends using both quantitative and qualitative data from a range of measures to assess outcomes. Evaluations should include pre- and post-comparisons, and consider both short-term and long-term outcomes. Specifically, evaluations should focus on a range of outcomes including creative production, personality, attitudes, and environmental factors. Using multiple measures can address weaknesses while strengthening evaluations.
Candidate young stellar objects in the S-cluster: Kinematic analysis of a sub...Sérgio Sacani
Context. The observation of several L-band emission sources in the S cluster has led to a rich discussion of their nature. However, a definitive answer to the classification of the dusty objects requires an explanation for the detection of compact Doppler-shifted Brγ emission. The ionized hydrogen in combination with the observation of mid-infrared L-band continuum emission suggests that most of these sources are embedded in a dusty envelope. These embedded sources are part of the S-cluster, and their relationship to the S-stars is still under debate. To date, the question of the origin of these two populations has been vague, although all explanations favor migration processes for the individual cluster members. Aims. This work revisits the S-cluster and its dusty members orbiting the supermassive black hole SgrA* on bound Keplerian orbits from a kinematic perspective. The aim is to explore the Keplerian parameters for patterns that might imply a nonrandom distribution of the sample. Additionally, various analytical aspects are considered to address the nature of the dusty sources. Methods. Based on the photometric analysis, we estimated the individual H−K and K−L colors for the source sample and compared the results to known cluster members. The classification revealed a noticeable contrast between the S-stars and the dusty sources. To fit the flux-density distribution, we utilized the radiative transfer code HYPERION and implemented a young stellar object Class I model. We obtained the position angle from the Keplerian fit results; additionally, we analyzed the distribution of the inclinations and the longitudes of the ascending node. Results. The colors of the dusty sources suggest a stellar nature consistent with the spectral energy distribution in the near and midinfrared domains. Furthermore, the evaporation timescales of dusty and gaseous clumps in the vicinity of SgrA* are much shorter ( 2yr) than the epochs covered by the observations (≈15yr). In addition to the strong evidence for the stellar classification of the D-sources, we also find a clear disk-like pattern following the arrangements of S-stars proposed in the literature. Furthermore, we find a global intrinsic inclination for all dusty sources of 60 ± 20◦, implying a common formation process. Conclusions. The pattern of the dusty sources manifested in the distribution of the position angles, inclinations, and longitudes of the ascending node strongly suggests two different scenarios: the main-sequence stars and the dusty stellar S-cluster sources share a common formation history or migrated with a similar formation channel in the vicinity of SgrA*. Alternatively, the gravitational influence of SgrA* in combination with a massive perturber, such as a putative intermediate mass black hole in the IRS 13 cluster, forces the dusty objects and S-stars to follow a particular orbital arrangement. Key words. stars: black holes– stars: formation– Galaxy: center– galaxies: star formation
CLASS 12th CHEMISTRY SOLID STATE ppt (Animated)eitps1506
Description:
Dive into the fascinating realm of solid-state physics with our meticulously crafted online PowerPoint presentation. This immersive educational resource offers a comprehensive exploration of the fundamental concepts, theories, and applications within the realm of solid-state physics.
From crystalline structures to semiconductor devices, this presentation delves into the intricate principles governing the behavior of solids, providing clear explanations and illustrative examples to enhance understanding. Whether you're a student delving into the subject for the first time or a seasoned researcher seeking to deepen your knowledge, our presentation offers valuable insights and in-depth analyses to cater to various levels of expertise.
Key topics covered include:
Crystal Structures: Unravel the mysteries of crystalline arrangements and their significance in determining material properties.
Band Theory: Explore the electronic band structure of solids and understand how it influences their conductive properties.
Semiconductor Physics: Delve into the behavior of semiconductors, including doping, carrier transport, and device applications.
Magnetic Properties: Investigate the magnetic behavior of solids, including ferromagnetism, antiferromagnetism, and ferrimagnetism.
Optical Properties: Examine the interaction of light with solids, including absorption, reflection, and transmission phenomena.
With visually engaging slides, informative content, and interactive elements, our online PowerPoint presentation serves as a valuable resource for students, educators, and enthusiasts alike, facilitating a deeper understanding of the captivating world of solid-state physics. Explore the intricacies of solid-state materials and unlock the secrets behind their remarkable properties with our comprehensive presentation.
Mending Clothing to Support Sustainable Fashion_CIMaR 2024.pdfSelcen Ozturkcan
Ozturkcan, S., Berndt, A., & Angelakis, A. (2024). Mending clothing to support sustainable fashion. Presented at the 31st Annual Conference by the Consortium for International Marketing Research (CIMaR), 10-13 Jun 2024, University of Gävle, Sweden.
Authoring a personal GPT for your research and practice: How we created the Q...Leonel Morgado
Thematic analysis in qualitative research is a time-consuming and systematic task, typically done using teams. Team members must ground their activities on common understandings of the major concepts underlying the thematic analysis, and define criteria for its development. However, conceptual misunderstandings, equivocations, and lack of adherence to criteria are challenges to the quality and speed of this process. Given the distributed and uncertain nature of this process, we wondered if the tasks in thematic analysis could be supported by readily available artificial intelligence chatbots. Our early efforts point to potential benefits: not just saving time in the coding process but better adherence to criteria and grounding, by increasing triangulation between humans and artificial intelligence. This tutorial will provide a description and demonstration of the process we followed, as two academic researchers, to develop a custom ChatGPT to assist with qualitative coding in the thematic data analysis process of immersive learning accounts in a survey of the academic literature: QUAL-E Immersive Learning Thematic Analysis Helper. In the hands-on time, participants will try out QUAL-E and develop their ideas for their own qualitative coding ChatGPT. Participants that have the paid ChatGPT Plus subscription can create a draft of their assistants. The organizers will provide course materials and slide deck that participants will be able to utilize to continue development of their custom GPT. The paid subscription to ChatGPT Plus is not required to participate in this workshop, just for trying out personal GPTs during it.
Anti-Universe And Emergent Gravity and the Dark UniverseSérgio Sacani
Recent theoretical progress indicates that spacetime and gravity emerge together from the entanglement structure of an underlying microscopic theory. These ideas are best understood in Anti-de Sitter space, where they rely on the area law for entanglement entropy. The extension to de Sitter space requires taking into account the entropy and temperature associated with the cosmological horizon. Using insights from string theory, black hole physics and quantum information theory we argue that the positive dark energy leads to a thermal volume law contribution to the entropy that overtakes the area law precisely at the cosmological horizon. Due to the competition between area and volume law entanglement the microscopic de Sitter states do not thermalise at sub-Hubble scales: they exhibit memory effects in the form of an entropy displacement caused by matter. The emergent laws of gravity contain an additional ‘dark’ gravitational force describing the ‘elastic’ response due to the entropy displacement. We derive an estimate of the strength of this extra force in terms of the baryonic mass, Newton’s constant and the Hubble acceleration scale a0 = cH0, and provide evidence for the fact that this additional ‘dark gravity force’ explains the observed phenomena in galaxies and clusters currently attributed to dark matter.
The cost of acquiring information by natural selectionCarl Bergstrom
This is a short talk that I gave at the Banff International Research Station workshop on Modeling and Theory in Population Biology. The idea is to try to understand how the burden of natural selection relates to the amount of information that selection puts into the genome.
It's based on the first part of this research paper:
The cost of information acquisition by natural selection
Ryan Seamus McGee, Olivia Kosterlitz, Artem Kaznatcheev, Benjamin Kerr, Carl T. Bergstrom
bioRxiv 2022.07.02.498577; doi: https://doi.org/10.1101/2022.07.02.498577
Evidence of Jet Activity from the Secondary Black Hole in the OJ 287 Binary S...Sérgio Sacani
Wereport the study of a huge optical intraday flare on 2021 November 12 at 2 a.m. UT in the blazar OJ287. In the binary black hole model, it is associated with an impact of the secondary black hole on the accretion disk of the primary. Our multifrequency observing campaign was set up to search for such a signature of the impact based on a prediction made 8 yr earlier. The first I-band results of the flare have already been reported by Kishore et al. (2024). Here we combine these data with our monitoring in the R-band. There is a big change in the R–I spectral index by 1.0 ±0.1 between the normal background and the flare, suggesting a new component of radiation. The polarization variation during the rise of the flare suggests the same. The limits on the source size place it most reasonably in the jet of the secondary BH. We then ask why we have not seen this phenomenon before. We show that OJ287 was never before observed with sufficient sensitivity on the night when the flare should have happened according to the binary model. We also study the probability that this flare is just an oversized example of intraday variability using the Krakow data set of intense monitoring between 2015 and 2023. We find that the occurrence of a flare of this size and rapidity is unlikely. In machine-readable Tables 1 and 2, we give the full orbit-linked historical light curve of OJ287 as well as the dense monitoring sample of Krakow.
EWOCS-I: The catalog of X-ray sources in Westerlund 1 from the Extended Weste...Sérgio Sacani
Context. With a mass exceeding several 104 M⊙ and a rich and dense population of massive stars, supermassive young star clusters
represent the most massive star-forming environment that is dominated by the feedback from massive stars and gravitational interactions
among stars.
Aims. In this paper we present the Extended Westerlund 1 and 2 Open Clusters Survey (EWOCS) project, which aims to investigate
the influence of the starburst environment on the formation of stars and planets, and on the evolution of both low and high mass stars.
The primary targets of this project are Westerlund 1 and 2, the closest supermassive star clusters to the Sun.
Methods. The project is based primarily on recent observations conducted with the Chandra and JWST observatories. Specifically,
the Chandra survey of Westerlund 1 consists of 36 new ACIS-I observations, nearly co-pointed, for a total exposure time of 1 Msec.
Additionally, we included 8 archival Chandra/ACIS-S observations. This paper presents the resulting catalog of X-ray sources within
and around Westerlund 1. Sources were detected by combining various existing methods, and photon extraction and source validation
were carried out using the ACIS-Extract software.
Results. The EWOCS X-ray catalog comprises 5963 validated sources out of the 9420 initially provided to ACIS-Extract, reaching a
photon flux threshold of approximately 2 × 10−8 photons cm−2
s
−1
. The X-ray sources exhibit a highly concentrated spatial distribution,
with 1075 sources located within the central 1 arcmin. We have successfully detected X-ray emissions from 126 out of the 166 known
massive stars of the cluster, and we have collected over 71 000 photons from the magnetar CXO J164710.20-455217.
The binding of cosmological structures by massless topological defectsSérgio Sacani
Assuming spherical symmetry and weak field, it is shown that if one solves the Poisson equation or the Einstein field
equations sourced by a topological defect, i.e. a singularity of a very specific form, the result is a localized gravitational
field capable of driving flat rotation (i.e. Keplerian circular orbits at a constant speed for all radii) of test masses on a thin
spherical shell without any underlying mass. Moreover, a large-scale structure which exploits this solution by assembling
concentrically a number of such topological defects can establish a flat stellar or galactic rotation curve, and can also deflect
light in the same manner as an equipotential (isothermal) sphere. Thus, the need for dark matter or modified gravity theory is
mitigated, at least in part.
1. Discussion on Innovation
Disclaimer: I’m not going to talk about innovation because it
means so many different things to different people. I am going
to talk about the importance of protecting and fostering scientific
creativity – as this is the fragile flower upon which scientific
innovation depends. And it is being endangered.
Jim Lepock Symposium, June 7, 2016
2. The Problem with Scientific Research
Research is inherently unpredictable and the only thing
going for it is that it inexpliquably, but consistently, delivers
new ideas, new ways of doing things and new benefits to
society.
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Promises
(in Klingon words)
Something..
Maybe
in 10 years..
3. Science is Terribly Inefficient, Corrupt & Fraudulent!
Inefficient: Funders can’t accurately predict
where the next advance will come from.
This, err, FRUSTRATES them.
Solution: Regulate!
Fraud: Everyday claims of irreproducibility,
plagiarism, outright fraud. Can scientists
even be trusted?
Corrupt: Scientists get to decide who among
their fellow scientists are to be allocated
funds! How is this even a thing?
4. 1. Reduce scientific collusion through virtual review!
Bonus: saves travel and hotel expenses - double win!
2. Force grant applications to be written in a tightly
structured, inflexible manner to make it easier to judge by
less competent people. Fairer!
3. Make reviewing faster by removing feedback to
applicants. 90 minutes per application is enough! Bonus, no
renewable grants! Ideas good. Continuity bad.
4. Increase reporting burden on grants to keep check that
nefarious things aren’t being done. Invent expensive new
metrics and other quantification methods. Encourage short-
term impact stories to impress politicians.
Rescued by Administrative Solutions*
*any resemblance to CIHR policies purely coincidental
5. But Science Doesn’t Work that Way!
• Scientific impact typically lags 5-20 years and often
passes through *many* hands and minds
• Creativity is not quantifiable at the time it is occurring
• Science is a continuous, incremental learning process, it
learns from correcting its mistakes
• Science is largely non-formulaic (albeit, repetition is).
Also reason why “moonshots” in biology are doomed to
fail
• Most metrics lag (e.g. citations), those that don’t have
major issues (e.g. JIF)
• Won’t know (+ve or -ve) impact of science procedural change
until too late.
6. So What Can/Should We Do?
• Be more open and accessible!
• Be more communicative, but…..
• Enough with the hype! Educate, don’t exaggerate
• Public confidence in science is fragile (see persistence of
pseudoscience), never take it for granted
• Encourage risk, happenstance, challenge
• Seek and correct for bias (including career structure)
• Ask how many scientists can/should Canada support?
• Recognize full spectrum of research
• No level of misconduct is tolerable – see it, declare it