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BRAIN IMAGING
CT & MRI
Mamdouh Mahfouz MD
Professor of Radiology
Cairo University
ssregypt.com
Patient Preparation
Patient position
Technique
Scanogram [frontal, lateral]
Scan intervals
Orbito-meatal line:
From External Canthus
To Ext. Auditory meatus
Patient Preparation
Fasting 4- 6 hours
• Contrast material
[ Urographin, Telebrix, Isovest…] 1-2 ml/kg
• Anesthesia
Children, Uncooperative patients
Contrast material administration
Traumatic cases, CVS
Cold cases [headache, epilepsy,
signs of increased ICT, …]
NO
YES
4th Ventricle Cerebellar Hemispheres Vermis
Post. Fossa level
Pones
Middle
Cerbellar
Peduncle
Prepontine
Cistern
Ambean
Cistern
Basilar Art.
Vallecula
4th Ventricle
Medulla Oblongata
Cisterna Magna
Cerebellar Folia
Quadrigeminal Cistern
Midbrain
Aqueduct
of Sylvius
•
Ventricular anatomy
Quadrigeminal Cistern Occipital horn, Calc. pineal body
Quadrigeminal Cistern
Head of caudate
Lentiform nucleus
Thalamus
Internal Capsule
External Capsule
3rd Ventricle
Insula
Basal Ganglia
Quadrigeminal Cistern
Vellum interpositum
Retro-thalamic Cistern
Retro-thalamic Cistern
Sup.cerebellar Cistern
Quadrigeminal Cistern
Pineal body
Inter. Cerebr.
veins
Pineal body
Inter. Cerebr. veins
Vein of Galen
Retro-thalamic Cistern
Septum
Pleusedum
Body of caudate
F
O
F
P
F
T
O
F
P
O
P
P
T T
F
O
Corona Radiata
Corona Radiata (deep)
Centrum Semi-ovale (superf.)
CT Vascular Anatomy
ICA
ACA (a1)
ACA (a2)
MCA A. Communicating A.
Basilar A.
PCA
P. Comm. A.
Strong magnetic field and
Radiofrequency (RF) coils
• Imaging are created by the motion of hydrogen protons in response
to the applied radiofrequency
• Multiplanar imaging [ axial, sagittal, coronal ]
• Any MR examination should include T1 and T2 Weighted images
BRAIN MRI
Cisterna Magna
Prepontine
Cistern
Interpeduncular
Cistern
Quadrigeminal
Cistern
Cavum velum
interpositum
Subarachnoid Cisterns
Suprasellar Cistern
CLOSED MAGNET
OPEN MAGNET
OPEN MAGNET
EXTERMITY MAGNET
MR advantages
 Multiplanar imaging
 Tissue characterization
 No bone artifacts
 Shows blood vessels without contrast
• T1 WIs (TR< 800 msec TE 20 msec)
• T2 WIs (TR> 1000 msec TE> 80 msec)
• PD WIs (TR> 1000 msec TE= 20 msec)
• T1 WIs [CSF BLACK ]
• T2 WIs [CSF BRIGHT ]
• FLAIR WIs [ CSF BLACK ]
BRAIN MRI
BRAIN MRI
PROTOCOL
T1 T2 FLAIR
Low signal lesion = hypointense = dark
High signal lesion = hyperintense = bright
Intermediate signal = isointense = Gray
Signal intensity
Identify T1 weighted images (CSF low signal) and T2 Weighted
images (CSF high signal)
Assess the signal intensity of the structure or lesion in both T1
and T2 weighted images
Follow the well known common signal behavior
How to interpret MR Images ?!
T1[low signal] T2[low signal]
[Non mobile protons]
Cortical bone
Mature fibrous tissue ( ligaments and tendons)
Calcifications ( physiological, pathological)
Flowing blood in the vessels ( fast moving protons) (signal void)
Air in the sinuses, lungs,…( minimal hydrogen protons)
Others……..
Subacute blood [met Hb]
Others….
Fat ( subcutaneous fat, dermoid cyst,…)
Others….
T1[High signal] T2[High signal]
T1[High signal] T2[Low signal]
Any structure or lesion not listed before
• Fluids ( CSF, urine, pleural effusion, ascites.,…)
• Edema and infarctions
• Most of tumors
• Contrast injection [ Gd- DTPA] ++
T1[Low signal] T2[High signal]
Gadolinium – DTPA
0.1 – 0.2 mmol/kg body weight
Only T1 weighted images are obtained after Gd- DTPA injection
Differentiate SOLs
Assess activity of some lesions like MS
Assess post operative tumour recurrence
Trigeminal n.
Optic tract ,mamillary body, cerebral peduncle, substantia negra
Gyrus rectus
Amegdala , hippocampus, superior vermis
Interpeduncular
Cistern
Quadrigeminal
Cistern
Temporal Horn
Hippocampal Formation
(epilepsy)
Hippocampal region
Mesial temporal sclerosis
Choroidal fissure , Hippocampal tail , Vein of Galen
(Retrothalamic Cistern)
Seen in T1WIs
Not seen in FLAIR
No clinical correlation
Anatomic sites
Verchaw – Robben’s spaces (dilated perivascular spaces)
Grey matter : Whitish
White matter: Greyish
Anatomic localization [Lobes]
Corpus callosum delineation
Cranio cervical junction
Evaluation of the venous sinuses
Pituitary gland
Value of sagittal images
Pituitary gland, chiasm, hypothalamus
Hippocampal region
Skull base and posterior fossa
Trigeminal nerve
Vascular anatomy
Value of coronal images
MRI Vascular Anatomy
‫اليك‬ ‫نتوب‬ ‫و‬ ‫نستغفرك‬ ‫انت‬ ‫اال‬ ‫اله‬ ‫ال‬ ‫ان‬ ‫نشهد‬ ‫بحمدك‬ ‫و‬ ‫اللهم‬ ‫سبحانك‬
Thank you
Normal brain imaging in CT and MRI for medical students
Normal brain imaging in CT and MRI for medical students
Normal brain imaging in CT and MRI for medical students
Normal brain imaging in CT and MRI for medical students
Normal brain imaging in CT and MRI for medical students
Normal brain imaging in CT and MRI for medical students

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Normal brain imaging in CT and MRI for medical students