- Arthropoda is the largest phylum of animals, including insects, arachnids, crustaceans, and others. They are bilaterally symmetrical, segmented, and have jointed appendages and a chitinous exoskeleton.
- The phylum contains over 80% of all animal species. It is divided into subphyla including Trilobita, Chelicerata, and Mandibulata. Trilobites are extinct marine arthropods. Chelicerates include spiders, scorpions, and others. Mandibulates include insects, crustaceans, centipedes, and millipedes.
- Arthropods live in nearly all environments and have
purpose of delivering a speech varies depending on the occasion or the audience it is delivered to. A wedding speech, for example, is usually delivered to express a congratulatory remark to the newly wed couple or to propose a toast to the audience. In order to ensure a proper delivery of words and ideas, speakers may practice their speaking through speech exercises like tongue twisters.
This document discusses the classification and characteristics of amphibians. It covers the major orders of amphibians including Labyrinthodontia, Phyllospondyli, Lepospondyli, Apoda, Urodela, and Anura. Key characteristics like larval development, parental care strategies, and reproductive modes are described. Examples are provided to illustrate different amphibian groups and parental care behaviors like nest building, egg guarding, carrying eggs attached to the body, and ovoviviparity.
if you want to be a champion in the kingdom Animalia, then it is best for you .
this slide show covers all important features , characteristics of organisms under kingdom animalia
This document provides information about the phyla Echinodermata and Mollusca. It describes their general characteristics, classifications, reproduction, special features, and economic importance. Echinodermata are spiny-skinned marine animals without freshwater or terrestrial representatives. They have calcium carbonate ossicles in their skin and include sea stars, sea urchins, sand dollars, and sea cucumbers. Mollusca is the second largest phylum of invertebrates and includes snails, slugs, clams, squids, and octopuses. They are soft-bodied with some having shells. Both phyla play important ecological roles and have economic uses as food, ornament
The document compares and contrasts the characteristics of mollusks and annelids. Both phyla are bilaterally symmetrical with a soft body and internal coelom. They can live in various environments on land or in water. Mollusks have a hard shell that protects their soft body, while annelids move via alternating circular and longitudinal muscles. Both groups exhibit a range of reproductive strategies including asexual reproduction and hermaphroditism. They have organ systems that allow for respiration, circulation, digestion, and nerve conduction.
History of arthropods.
Relation with annelids.
Characteristic features.
Circulatory system.
Classification upto subphylum
Phylum Upto Classes
Metamrization
Tegmatization
Why Tegmatization is better?
Exoskeleton
Metamorphoses
Habitat and Adaptations
Economic Gains
Economic Losses
Presentation
Best of Luck
This document provides an overview of the classification of animals in the animal kingdom. It discusses the major taxonomic groups from the lowest level of Porifera to the highest level of mammals. Key points include:
- The animal kingdom is classified from the broadest category of kingdom down to more specific categories like phylum, class, order and species.
- Major phyla discussed include porifera, cnidaria, platyhelminthes, nematoda, annelida, arthropoda, mollusca, echinodermata, protochordata and vertebrata.
- Vertebrata is further divided into classes of pisces, amphibians, reptilia, aves
- Arthropoda is the largest phylum of animals, including insects, arachnids, crustaceans, and others. They are bilaterally symmetrical, segmented, and have jointed appendages and a chitinous exoskeleton.
- The phylum contains over 80% of all animal species. It is divided into subphyla including Trilobita, Chelicerata, and Mandibulata. Trilobites are extinct marine arthropods. Chelicerates include spiders, scorpions, and others. Mandibulates include insects, crustaceans, centipedes, and millipedes.
- Arthropods live in nearly all environments and have
purpose of delivering a speech varies depending on the occasion or the audience it is delivered to. A wedding speech, for example, is usually delivered to express a congratulatory remark to the newly wed couple or to propose a toast to the audience. In order to ensure a proper delivery of words and ideas, speakers may practice their speaking through speech exercises like tongue twisters.
This document discusses the classification and characteristics of amphibians. It covers the major orders of amphibians including Labyrinthodontia, Phyllospondyli, Lepospondyli, Apoda, Urodela, and Anura. Key characteristics like larval development, parental care strategies, and reproductive modes are described. Examples are provided to illustrate different amphibian groups and parental care behaviors like nest building, egg guarding, carrying eggs attached to the body, and ovoviviparity.
if you want to be a champion in the kingdom Animalia, then it is best for you .
this slide show covers all important features , characteristics of organisms under kingdom animalia
This document provides information about the phyla Echinodermata and Mollusca. It describes their general characteristics, classifications, reproduction, special features, and economic importance. Echinodermata are spiny-skinned marine animals without freshwater or terrestrial representatives. They have calcium carbonate ossicles in their skin and include sea stars, sea urchins, sand dollars, and sea cucumbers. Mollusca is the second largest phylum of invertebrates and includes snails, slugs, clams, squids, and octopuses. They are soft-bodied with some having shells. Both phyla play important ecological roles and have economic uses as food, ornament
The document compares and contrasts the characteristics of mollusks and annelids. Both phyla are bilaterally symmetrical with a soft body and internal coelom. They can live in various environments on land or in water. Mollusks have a hard shell that protects their soft body, while annelids move via alternating circular and longitudinal muscles. Both groups exhibit a range of reproductive strategies including asexual reproduction and hermaphroditism. They have organ systems that allow for respiration, circulation, digestion, and nerve conduction.
History of arthropods.
Relation with annelids.
Characteristic features.
Circulatory system.
Classification upto subphylum
Phylum Upto Classes
Metamrization
Tegmatization
Why Tegmatization is better?
Exoskeleton
Metamorphoses
Habitat and Adaptations
Economic Gains
Economic Losses
Presentation
Best of Luck
This document provides an overview of the classification of animals in the animal kingdom. It discusses the major taxonomic groups from the lowest level of Porifera to the highest level of mammals. Key points include:
- The animal kingdom is classified from the broadest category of kingdom down to more specific categories like phylum, class, order and species.
- Major phyla discussed include porifera, cnidaria, platyhelminthes, nematoda, annelida, arthropoda, mollusca, echinodermata, protochordata and vertebrata.
- Vertebrata is further divided into classes of pisces, amphibians, reptilia, aves
This document summarizes a presentation about reptile classification given by Deepak Rawal. It discusses the general characteristics of reptiles and provides a classification of living reptiles into four orders: Chelonia (turtles), Rhynchocephalia (tuatara), Crocodilia (crocodiles), and Squamata (lizards and snakes). Within Squamata, lizards are classified under Lacertilia and snakes under Ophidia. Key differences between lizards and snakes are outlined. Information on poisonous and non-poisonous snakes in India is also provided.
This document provides an overview of the animal kingdom, summarizing key characteristics of different phyla. It begins with sponges, then discusses cnidarians, ctenophores, flatworms, roundworms, segmented worms, arthropods, mollusks, echinoderms, hemichordates, and chordates. Within chordates, it describes the subphyla of tunicates, cephalochordates, and vertebrates. For each group, it highlights levels of organization, symmetry, body plan features, and examples. The document serves as a comprehensive guide to classifying and comparing the main animal phyla.
Cnidarians are a phylum of aquatic animals that include jellyfish, corals, sea anemones and hydroids. They are radially symmetrical with a mouth surrounded by tentacles, and have stinging cells called nematocysts. Many cnidarians alternate between sessile polyp and motile medusa body forms. Their body wall is composed of two tissue layers with a jelly-like mesoglea in between. They have a nerve net and gastrovascular cavity for digestion and gas exchange. The five classes are Hydrozoa, Scyphozoa, Staurozoa, Cubozoa and Anthozoa.
algae uses of algae types of algae reproduction of algaeRAHUL SINWER
This document provides information on algae, including their key characteristics, habitats, structures, and modes of reproduction. Some key points:
- Algae are chlorophyll-bearing thallophytes that can be unicellular or multicellular. They live in aquatic and moist habitats.
- Their structures range from single-celled to complex multicellular forms. Reproduction can occur vegetatively or sexually through spores and gametes of different types depending on the species.
- They are found in a variety of aquatic and terrestrial habitats. Different algal groups are named based on their specific habitats, such as aquatic, edaphic, aerial, cryophytic, symbiotic, endozoic
The document provides information about the different types of animals that make up the animal kingdom. It discusses invertebrates like sponges, cnidarians, flatworms, roundworms, segmented worms, mollusks, echinoderms, and arthropods. It describes their characteristics, habitats, life cycles, and examples. It also covers vertebrates and provides details on specific invertebrate groups like crustaceans, arachnids, insects, and more. The document aims to educate about the diversity of life that makes up the animal kingdom.
Arthropods are segmented animals with jointed appendages, an exoskeleton, and a body divided into three parts. They include insects, spiders, crabs, and others. Arthropods have a complete digestive system, respiratory systems like gills or trachea, and open circulatory systems. They are found worldwide and are important as food, for agriculture, and unfortunately can transmit diseases. The phylum is divided into subphylums including Trilobitomorpha, Chelicerata, Myriapoda, Crustacea, and Hexapoda.
Cephalochordata, including Branchiostoma, are marine chordates found in shallow waters. They have a small, slender, fish-like body with a notochord extending its entire length. While they possess some primitive chordate features, such as a dorsal nerve cord, they lack specialized structures like a head or paired limbs. Their affinities to other groups are debated, but they are generally considered a primitive chordate subphylum that diverged early in chordate evolution.
This document summarizes the larval forms of two parasitic flatworms: trematodes and cestodes. It describes 5 larval forms in the life cycle of Fasciola hepatica: miracidium, sporocyst, redia, cercaria, and metacercaria. It also describes 2 larval forms in the life cycle of Taenia solium: the hexacanth larva (also called onchosphere) and the cysticercus larva. The cysticercus larva lives in the muscle of pigs.
This document discusses the kingdom Animalia. It begins by defining animals and describing their general characteristics of being eukaryotic, multicellular, heterotrophic organisms that ingest nutrients. It then examines the classification of animals, describing the major groups like sponges, cnidarians, flatworms, roundworms, and more complex bilaterally symmetrical animals. It provides examples of representative species for each group and their distinguishing features.
The document discusses examination of sputum. Sputum is normally cleared from the lungs by cilia, but excess collects when coughing. Sputum should be collected in sterile containers and examined while fresh. Physical properties like color, consistency and cell content provide clinical information. Microscopic examination of stained sputum smears allows identification of cells, parasites, fungi and pathogens like tubercle bacilli. Analysis of sputum properties aids diagnosis of lung conditions.
This document provides an overview of the structural organization and classification of the animal kingdom. It discusses the key characteristics and examples of each phylum, including Protozoa, Porifera, Coelenterata, Ctenophora, Platyhelminthes, Aschelminths, Annelida, Arthropoda, Mollusca, Echinodermata, Hemichordata, Cephalochordata, Urochordata, true chordates such as fish, amphibians, reptiles, birds and mammals. For each group, it summarizes distinguishing features and provides examples of types of organisms that belong to that group.
1. The document discusses two phyla - Arthropoda and Echinodermata. It describes the general characteristics and representative classes of each phylum.
2. For Arthropoda, it outlines the characteristics like jointed exoskeleton and segmented body and lists the classes Insecta, Crustacea, Arachnida, etc. It also describes the life cycles of insects like dragonflies and butterflies.
3. For Echinodermata, it discusses the spiny skin, water vascular system and radial symmetry. It provides details on the classes Asteroidea, Holothuroidea, Crinoidea, Echinoidea and Ophiuroidea with examples like sea stars
The document provides information about the phylum Annelida, specifically focusing on the classes Polychaeta, Oligochaeta, and Hirudinea. Some key points:
1) Annelida are metameric, bilaterally symmetrical worms with a closed circulatory system. They display both metamerism and sometimes tagmatization.
2) Polychaeta are mostly marine worms with parapodia and setae. They include sand worms, blood worms, and tube-dwelling filter feeders.
3) Oligochaeta include soil-building earthworms. They lack parapodia and have a clitellum and prostomium for burrowing.
4
This document provides information about vertebrates. It discusses the five main groups of vertebrates - fish, amphibians, reptiles, birds, and mammals. All vertebrates have an endoskeleton, head, trunk, and some have a tail. They also have articulated limbs, a well-developed nervous system, and bilateral symmetry. The document contrasts exothermic and endothermic animals and provides examples from different vertebrate groups. It provides details on characteristics of different vertebrate groups like fish, amphibians, reptiles, birds, and mammals. Examples are given for different types of animals and there are questions provided for students.
Phylum Arthropoda includes insects, crustaceans, arachnids and makes up over 82% of all living things. They are characterized by having a segmented body, jointed appendages, and an exoskeleton made of chitin. Arthropods have a head with sensory organs and mouthparts, a thorax for appendage attachment, and some have an abdomen. Their exoskeleton provides protection but limits growth, requiring molting. They are bilaterally symmetrical, triploblastic, and have open circulatory, digestive and nervous systems adapted for their habitat.
This document summarizes key aspects of crustacean anatomy and evolution. It describes how crustaceans evolved specialized limbs for locomotion, feeding, respiration and sensing. Their bodies shortened as limb functions increased. Many developed a carapace for protection. These factors led to six subclasses. The subclasses differ in features like feeding method, presence of a carapace, and limb specialization. The document also outlines general crustacean anatomy including cuticle, somites, tagmata, nervous system, senses, digestion, respiration, circulation and reproduction.
The document summarizes amniotes and their evolution. It discusses:
1) Amniotes are tetrapods with an amniotic egg, including mammals, reptiles, and birds. The amniotic egg allowed reproduction on land.
2) Modern amniotes are classified as synapsids (mammals), anapsids (turtles), or diapsids (reptiles and birds). Diapsids split into lepidosaurs and archosaurs.
3) Reptiles evolved from amphibians and gained adaptations like scaly skin, internal fertilization, and efficient lungs and kidneys for land survival.
This document summarizes the key marine arthropod classes. It describes their general characteristics including bilateral symmetry, exoskeleton, molting, digestion, and circulatory and nervous systems. The major classes included are Malacostraca, Branchiopoda, Ostracoda, Copepoda, Pentastomida, and Cirripedia. These classes are distinguished by features like body plan, habitat, appendages, life cycle, and ecology.
Cell Therapy Expansion and Challenges in Autoimmune DiseaseHealth Advances
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
Are you looking for a long-lasting solution to your missing tooth?
Dental implants are the most common type of method for replacing the missing tooth. Unlike dentures or bridges, implants are surgically placed in the jawbone. In layman’s terms, a dental implant is similar to the natural root of the tooth. It offers a stable foundation for the artificial tooth giving it the look, feel, and function similar to the natural tooth.
More Related Content
Similar to Nine Phylum of Invertibrates by Tesula Parajuli
This document summarizes a presentation about reptile classification given by Deepak Rawal. It discusses the general characteristics of reptiles and provides a classification of living reptiles into four orders: Chelonia (turtles), Rhynchocephalia (tuatara), Crocodilia (crocodiles), and Squamata (lizards and snakes). Within Squamata, lizards are classified under Lacertilia and snakes under Ophidia. Key differences between lizards and snakes are outlined. Information on poisonous and non-poisonous snakes in India is also provided.
This document provides an overview of the animal kingdom, summarizing key characteristics of different phyla. It begins with sponges, then discusses cnidarians, ctenophores, flatworms, roundworms, segmented worms, arthropods, mollusks, echinoderms, hemichordates, and chordates. Within chordates, it describes the subphyla of tunicates, cephalochordates, and vertebrates. For each group, it highlights levels of organization, symmetry, body plan features, and examples. The document serves as a comprehensive guide to classifying and comparing the main animal phyla.
Cnidarians are a phylum of aquatic animals that include jellyfish, corals, sea anemones and hydroids. They are radially symmetrical with a mouth surrounded by tentacles, and have stinging cells called nematocysts. Many cnidarians alternate between sessile polyp and motile medusa body forms. Their body wall is composed of two tissue layers with a jelly-like mesoglea in between. They have a nerve net and gastrovascular cavity for digestion and gas exchange. The five classes are Hydrozoa, Scyphozoa, Staurozoa, Cubozoa and Anthozoa.
algae uses of algae types of algae reproduction of algaeRAHUL SINWER
This document provides information on algae, including their key characteristics, habitats, structures, and modes of reproduction. Some key points:
- Algae are chlorophyll-bearing thallophytes that can be unicellular or multicellular. They live in aquatic and moist habitats.
- Their structures range from single-celled to complex multicellular forms. Reproduction can occur vegetatively or sexually through spores and gametes of different types depending on the species.
- They are found in a variety of aquatic and terrestrial habitats. Different algal groups are named based on their specific habitats, such as aquatic, edaphic, aerial, cryophytic, symbiotic, endozoic
The document provides information about the different types of animals that make up the animal kingdom. It discusses invertebrates like sponges, cnidarians, flatworms, roundworms, segmented worms, mollusks, echinoderms, and arthropods. It describes their characteristics, habitats, life cycles, and examples. It also covers vertebrates and provides details on specific invertebrate groups like crustaceans, arachnids, insects, and more. The document aims to educate about the diversity of life that makes up the animal kingdom.
Arthropods are segmented animals with jointed appendages, an exoskeleton, and a body divided into three parts. They include insects, spiders, crabs, and others. Arthropods have a complete digestive system, respiratory systems like gills or trachea, and open circulatory systems. They are found worldwide and are important as food, for agriculture, and unfortunately can transmit diseases. The phylum is divided into subphylums including Trilobitomorpha, Chelicerata, Myriapoda, Crustacea, and Hexapoda.
Cephalochordata, including Branchiostoma, are marine chordates found in shallow waters. They have a small, slender, fish-like body with a notochord extending its entire length. While they possess some primitive chordate features, such as a dorsal nerve cord, they lack specialized structures like a head or paired limbs. Their affinities to other groups are debated, but they are generally considered a primitive chordate subphylum that diverged early in chordate evolution.
This document summarizes the larval forms of two parasitic flatworms: trematodes and cestodes. It describes 5 larval forms in the life cycle of Fasciola hepatica: miracidium, sporocyst, redia, cercaria, and metacercaria. It also describes 2 larval forms in the life cycle of Taenia solium: the hexacanth larva (also called onchosphere) and the cysticercus larva. The cysticercus larva lives in the muscle of pigs.
This document discusses the kingdom Animalia. It begins by defining animals and describing their general characteristics of being eukaryotic, multicellular, heterotrophic organisms that ingest nutrients. It then examines the classification of animals, describing the major groups like sponges, cnidarians, flatworms, roundworms, and more complex bilaterally symmetrical animals. It provides examples of representative species for each group and their distinguishing features.
The document discusses examination of sputum. Sputum is normally cleared from the lungs by cilia, but excess collects when coughing. Sputum should be collected in sterile containers and examined while fresh. Physical properties like color, consistency and cell content provide clinical information. Microscopic examination of stained sputum smears allows identification of cells, parasites, fungi and pathogens like tubercle bacilli. Analysis of sputum properties aids diagnosis of lung conditions.
This document provides an overview of the structural organization and classification of the animal kingdom. It discusses the key characteristics and examples of each phylum, including Protozoa, Porifera, Coelenterata, Ctenophora, Platyhelminthes, Aschelminths, Annelida, Arthropoda, Mollusca, Echinodermata, Hemichordata, Cephalochordata, Urochordata, true chordates such as fish, amphibians, reptiles, birds and mammals. For each group, it summarizes distinguishing features and provides examples of types of organisms that belong to that group.
1. The document discusses two phyla - Arthropoda and Echinodermata. It describes the general characteristics and representative classes of each phylum.
2. For Arthropoda, it outlines the characteristics like jointed exoskeleton and segmented body and lists the classes Insecta, Crustacea, Arachnida, etc. It also describes the life cycles of insects like dragonflies and butterflies.
3. For Echinodermata, it discusses the spiny skin, water vascular system and radial symmetry. It provides details on the classes Asteroidea, Holothuroidea, Crinoidea, Echinoidea and Ophiuroidea with examples like sea stars
The document provides information about the phylum Annelida, specifically focusing on the classes Polychaeta, Oligochaeta, and Hirudinea. Some key points:
1) Annelida are metameric, bilaterally symmetrical worms with a closed circulatory system. They display both metamerism and sometimes tagmatization.
2) Polychaeta are mostly marine worms with parapodia and setae. They include sand worms, blood worms, and tube-dwelling filter feeders.
3) Oligochaeta include soil-building earthworms. They lack parapodia and have a clitellum and prostomium for burrowing.
4
This document provides information about vertebrates. It discusses the five main groups of vertebrates - fish, amphibians, reptiles, birds, and mammals. All vertebrates have an endoskeleton, head, trunk, and some have a tail. They also have articulated limbs, a well-developed nervous system, and bilateral symmetry. The document contrasts exothermic and endothermic animals and provides examples from different vertebrate groups. It provides details on characteristics of different vertebrate groups like fish, amphibians, reptiles, birds, and mammals. Examples are given for different types of animals and there are questions provided for students.
Phylum Arthropoda includes insects, crustaceans, arachnids and makes up over 82% of all living things. They are characterized by having a segmented body, jointed appendages, and an exoskeleton made of chitin. Arthropods have a head with sensory organs and mouthparts, a thorax for appendage attachment, and some have an abdomen. Their exoskeleton provides protection but limits growth, requiring molting. They are bilaterally symmetrical, triploblastic, and have open circulatory, digestive and nervous systems adapted for their habitat.
This document summarizes key aspects of crustacean anatomy and evolution. It describes how crustaceans evolved specialized limbs for locomotion, feeding, respiration and sensing. Their bodies shortened as limb functions increased. Many developed a carapace for protection. These factors led to six subclasses. The subclasses differ in features like feeding method, presence of a carapace, and limb specialization. The document also outlines general crustacean anatomy including cuticle, somites, tagmata, nervous system, senses, digestion, respiration, circulation and reproduction.
The document summarizes amniotes and their evolution. It discusses:
1) Amniotes are tetrapods with an amniotic egg, including mammals, reptiles, and birds. The amniotic egg allowed reproduction on land.
2) Modern amniotes are classified as synapsids (mammals), anapsids (turtles), or diapsids (reptiles and birds). Diapsids split into lepidosaurs and archosaurs.
3) Reptiles evolved from amphibians and gained adaptations like scaly skin, internal fertilization, and efficient lungs and kidneys for land survival.
This document summarizes the key marine arthropod classes. It describes their general characteristics including bilateral symmetry, exoskeleton, molting, digestion, and circulatory and nervous systems. The major classes included are Malacostraca, Branchiopoda, Ostracoda, Copepoda, Pentastomida, and Cirripedia. These classes are distinguished by features like body plan, habitat, appendages, life cycle, and ecology.
Similar to Nine Phylum of Invertibrates by Tesula Parajuli (20)
Cell Therapy Expansion and Challenges in Autoimmune DiseaseHealth Advances
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
Are you looking for a long-lasting solution to your missing tooth?
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Travel vaccination in Manchester offers comprehensive immunization services for individuals planning international trips. Expert healthcare providers administer vaccines tailored to your destination, ensuring you stay protected against various diseases. Conveniently located clinics and flexible appointment options make it easy to get the necessary shots before your journey. Stay healthy and travel with confidence by getting vaccinated in Manchester. Visit us: www.nxhealthcare.co.uk
Test bank for karp s cell and molecular biology 9th edition by gerald karp.pdfrightmanforbloodline
Test bank for karp s cell and molecular biology 9th edition by gerald karp.pdf
Test bank for karp s cell and molecular biology 9th edition by gerald karp.pdf
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Breast cancer: Post menopausal endocrine therapyDr. Sumit KUMAR
Breast cancer in postmenopausal women with hormone receptor-positive (HR+) status is a common and complex condition that necessitates a multifaceted approach to management. HR+ breast cancer means that the cancer cells grow in response to hormones such as estrogen and progesterone. This subtype is prevalent among postmenopausal women and typically exhibits a more indolent course compared to other forms of breast cancer, which allows for a variety of treatment options.
Diagnosis and Staging
The diagnosis of HR+ breast cancer begins with clinical evaluation, imaging, and biopsy. Imaging modalities such as mammography, ultrasound, and MRI help in assessing the extent of the disease. Histopathological examination and immunohistochemical staining of the biopsy sample confirm the diagnosis and hormone receptor status by identifying the presence of estrogen receptors (ER) and progesterone receptors (PR) on the tumor cells.
Staging involves determining the size of the tumor (T), the involvement of regional lymph nodes (N), and the presence of distant metastasis (M). The American Joint Committee on Cancer (AJCC) staging system is commonly used. Accurate staging is critical as it guides treatment decisions.
Treatment Options
Endocrine Therapy
Endocrine therapy is the cornerstone of treatment for HR+ breast cancer in postmenopausal women. The primary goal is to reduce the levels of estrogen or block its effects on cancer cells. Commonly used agents include:
Selective Estrogen Receptor Modulators (SERMs): Tamoxifen is a SERM that binds to estrogen receptors, blocking estrogen from stimulating breast cancer cells. It is effective but may have side effects such as increased risk of endometrial cancer and thromboembolic events.
Aromatase Inhibitors (AIs): These drugs, including anastrozole, letrozole, and exemestane, lower estrogen levels by inhibiting the aromatase enzyme, which converts androgens to estrogen in peripheral tissues. AIs are generally preferred in postmenopausal women due to their efficacy and safety profile compared to tamoxifen.
Selective Estrogen Receptor Downregulators (SERDs): Fulvestrant is a SERD that degrades estrogen receptors and is used in cases where resistance to other endocrine therapies develops.
Combination Therapies
Combining endocrine therapy with other treatments enhances efficacy. Examples include:
Endocrine Therapy with CDK4/6 Inhibitors: Palbociclib, ribociclib, and abemaciclib are CDK4/6 inhibitors that, when combined with endocrine therapy, significantly improve progression-free survival in advanced HR+ breast cancer.
Endocrine Therapy with mTOR Inhibitors: Everolimus, an mTOR inhibitor, can be added to endocrine therapy for patients who have developed resistance to aromatase inhibitors.
Chemotherapy
Chemotherapy is generally reserved for patients with high-risk features, such as large tumor size, high-grade histology, or extensive lymph node involvement. Regimens often include anthracyclines and taxanes.
5-hydroxytryptamine or 5-HT or Serotonin is a neurotransmitter that serves a range of roles in the human body. It is sometimes referred to as the happy chemical since it promotes overall well-being and happiness.
It is mostly found in the brain, intestines, and blood platelets.
5-HT is utilised to transport messages between nerve cells, is known to be involved in smooth muscle contraction, and adds to overall well-being and pleasure, among other benefits. 5-HT regulates the body's sleep-wake cycles and internal clock by acting as a precursor to melatonin.
It is hypothesised to regulate hunger, emotions, motor, cognitive, and autonomic processes.
NAVIGATING THE HORIZONS OF TIME LAPSE EMBRYO MONITORING.pdfRahul Sen
Time-lapse embryo monitoring is an advanced imaging technique used in IVF to continuously observe embryo development. It captures high-resolution images at regular intervals, allowing embryologists to select the most viable embryos for transfer based on detailed growth patterns. This technology enhances embryo selection, potentially increasing pregnancy success rates.
Histololgy of Female Reproductive System.pptxAyeshaZaid1
Dive into an in-depth exploration of the histological structure of female reproductive system with this comprehensive lecture. Presented by Dr. Ayesha Irfan, Assistant Professor of Anatomy, this presentation covers the Gross anatomy and functional histology of the female reproductive organs. Ideal for students, educators, and anyone interested in medical science, this lecture provides clear explanations, detailed diagrams, and valuable insights into female reproductive system. Enhance your knowledge and understanding of this essential aspect of human biology.
low birth weight presentation. Low birth weight (LBW) infant is defined as the one whose birth weight is less than 2500g irrespective of their gestational age. Premature birth and low birth weight(LBW) is still a serious problem in newborn. Causing high morbidity and mortality rate worldwide. The nursing care provide to low birth weight babies is crucial in promoting their overall health and development. Through careful assessment, diagnosis,, planning, and evaluation plays a vital role in ensuring these vulnerable infants receive the specialize care they need. In India every third of the infant weight less than 2500g.
Birth period, socioeconomical status, nutritional and intrauterine environment are the factors influencing low birth weight
Osteoporosis - Definition , Evaluation and Management .pdfJim Jacob Roy
Osteoporosis is an increasing cause of morbidity among the elderly.
In this document , a brief outline of osteoporosis is given , including the risk factors of osteoporosis fractures , the indications for testing bone mineral density and the management of osteoporosis
- Video recording of this lecture in English language: https://youtu.be/Pt1nA32sdHQ
- Video recording of this lecture in Arabic language: https://youtu.be/uFdc9F0rlP0
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
10 Benefits an EPCR Software should Bring to EMS Organizations Traumasoft LLC
The benefits of an ePCR solution should extend to the whole EMS organization, not just certain groups of people or certain departments. It should provide more than just a form for entering and a database for storing information. It should also include a workflow of how information is communicated, used and stored across the entire organization.
Co-Chairs, Val J. Lowe, MD, and Cyrus A. Raji, MD, PhD, prepared useful Practice Aids pertaining to Alzheimer’s disease for this CME/AAPA activity titled “Alzheimer’s Disease Case Conference: Gearing Up for the Expanding Role of Neuroradiology in Diagnosis and Treatment.” For the full presentation, downloadable Practice Aids, and complete CME/AAPA information, and to apply for credit, please visit us at https://bit.ly/3PvVY25. CME/AAPA credit will be available until June 28, 2025.
Nano-gold for Cancer Therapy chemistry investigatory projectSIVAVINAYAKPK
chemistry investigatory project
The development of nanogold-based cancer therapy could revolutionize oncology by providing a more targeted, less invasive treatment option. This project contributes to the growing body of research aimed at harnessing nanotechnology for medical applications, paving the way for future clinical trials and potential commercial applications.
Cancer remains one of the leading causes of death worldwide, prompting the need for innovative treatment methods. Nanotechnology offers promising new approaches, including the use of gold nanoparticles (nanogold) for targeted cancer therapy. Nanogold particles possess unique physical and chemical properties that make them suitable for drug delivery, imaging, and photothermal therapy.
3. PORIFERA
• EXCLUSIVELY MARINE ANIMALS, DIPLOBLASTIC
• MULTICELLULAR, BUT TISSUES ARE ABSENT.
• RADIAL SYMMETRICAL OR ASYMMETRICAL
• HAVE PORES.
• SMALL AND NUMEROUS PORES ARE CALLED OSTIA.
• SINGLE AND LONGER PORE IS CALLED OSCULUM.
• RESPIRE THROUGH GENERAL BODY SURFACE.
• EXAMPLE: SYCON, SPONGE, SPONGILLA, ETC.
Fig. Sponge
Fig. Sycon
4. COELENTERATA
• MULTICELLULAR, DIPLOBLASTIC
• HAVE TISSUE GRADE OF ORGANIZATION
• ALIMENTARY CANAL IS INCOMPLETE
• HAVE TENTACLES ON MOUTH
• BODY ENCLOSE A HOLLOW BODY CAVITY CALLED COELENTERON.
• BISEXUAL OR HERMAPHRODITE
• RESPIRE THROUGH GENERAL BODY SURFACE.
• EXAMPLE: HYDRA, JELLYFISH, CORAL, ETC.
5. PLATYHELMINTHES
• BODY IS FLAT I.E. RIBBON LIKE OR LEAF LIKE.
• HERMAPHRODITE,TRIPLOBLASTIC.
• ALIMENTARY CANAL IS INCOMPLETE.
• BODY HAS BILATERAL SYMMETRY.
• THEY ARE MOSTLY PARASITES.
• RESPIRE THROUGH GENERAL BODY SURFACES.
• EXAMPLE:TAPEWORM,RIVERFLUKE, BLOODFLUKE
6. NEMATHELMINTHES
• HAVE ELONGATED , CYLINDRICAL AND ROUND BODY WITH TAPERED ENDS .
• UNISEXUAL,TRIPLOBLASTIC,PARASITES
• HAVE COMPLETE ALIMENTARY CANAL.
• HAVE BILATERAL SYMMETRY.
• REPRODUCE ONLY BY SEXUAL METHOD.
• EXAMPLES:PINWORM,HOOKWORM,ETC.
7. ANNELIDA
• HAVE ELONGATED,CYLINDRICAL AND SEGMENTED BODY WITH NUMEROUS RINGS.
• TRIPLOBLASTIC AND HAVE BILATERAL SYMMETRY
• MOSTLY BISEXUAL, HAVE HIGH REGENERATION CAPACITY.
• FOUND IN MOIST LAND AND IN WATER
• EXCRETE THROUGH NEPHRIDIA.
• RESPIRATION OCCURS THROUGH GENERAL MOIST SKIN.
• NERVOUS SYSTEM CONSISTS OF NERVE RING, NERVE CORD AND NERVES.
• EXAMPLE: SANDWORM, EARTHWORM, LEECH, ETC.
8. ARTHROPEDA
• HAVE JOINTED APPENDAGES
• ARE FOUND IN AIR, LAND, WATER
• BODY DIVIDED INTO HEAD, THORAX AND ABDOMEN
• IN SOME ANIMALS,HEAD AND THORAX ARE FOUND TO FORM CEPHALON THORAX.
• ARE UNISEXUAL, TRIPLOBLASTIC AND BILATERAL SYMMETRY
• RESPIRE THROUGH GILLS , TRACHEA AND GENERAL BODY SURFACE.
• EXAMPLES: BUTTERFLY ,MOTH ,ANT ,DRAGONFLY , ETC.
9. MOLLUSCA
• SOFT BODY,COVERED BY HARD SHELL MADE WITH CACO3
• BODY DIVIDED INTO FOUR PARTS I.E. HEAD, MUSCULAR FOOT, VISCERALMASS AND MANTLE
• TENTACLES WITH EYES ARE PRESENT
• TRIPLOBLASTIC AND ASYMMETRICAL
• FOUND ON LAND OR IN WATER, USUALLY UNISEXUAL
• RESPIRE THROUGH GILLS OR PULMONARY SACS OR GENERAL BODY SURFACE
• EXAMPLES: OCTOPUS ,SNAIL , ETC
10. ECHINODERMATA
• HAVE SPINES ON THEIR SKINS
• FOUND IN SEA WATER, RESPIRE THROUGH GILLS
• HAVE NO DISTINCT HEAD
• MOVE WITH THE HELP OF TUBE-FEET
• TRIPLOBLASTIC AND RADIAL SYMMETRY
• UNISEXUAL
• BODY SHAPE IS GLOBULAR, VASE-LIKE, STAR-LIKE, SPHERICAL OR ELONGATED.
• EXAMPLE: SEA CUCUMBER, SEA LILY, STARFISH, ETC.