nilavembu

1. DR. B. KARUNAI SELVI
ASSISTANT PROFESSOR OF BOTANY
V.V.VANNIAPERUMAL COLLEGE FOR
WOMEN, VIRUDHUNAGAR – 626 001
TAMIL NADU
NILAVEMBU KUDINEER –
A POLYHERBAL FORMULATION AGAINST
DENGUE VIRUS

2. INTRODUCTION
 Dengue epidemic has become an important focus of
international public health awareness.
 It is found mainly in tropical and sub-tropical
regions of the world, mostly in urban and semi-
urban areas .
 Dengue is considered as an important mosquito-
borne arboviral disease.
 According to World Health Organization (WHO),
dengue is a febrile illness that affects infants,
children and adults.

3. DENGUE VIRUS
Dengue fever is a painful, debilitating
mosquito-borne disease caused by any one of
four closely related dengue viruses

4. DENGUE
 Most cases occur in tropical areas of the world, with the
greatest risk occurring in:
 The Indian subcontinent
 Southeast Asia
 Southern China
 Taiwan
 The Pacific Islands
 The Caribbean (except Cuba and the Cayman Islands)
 Mexico
 Africa

5. DENGUE
 Dengue fever is transmitted by the bite of an Aedes
mosquito infected with a dengue virus.
 The mosquito becomes infected when it bites a
person with dengue virus in their blood.
 It can’t be spread directly from one person to
another person.

6. SYMPTOMS OF DENGUE FEVER
 Sudden, high fever
 Severe headaches
 Pain behind the eyes
 Severe joint and muscle pain
 Fatigue
 Nausea
 Vomiting
 Skin rash, which appears two to five days after the onset
of fever
 Mild bleeding (such a nose bleed, bleeding gums, or easy
bruising)

7. TREATMENT
 The treatment of dengue fever is symptomatic and
supportive in nature.
 Bed rest and mild analgesic-antipyretic
therapy are often helpful in relieving lethargy,
malaise, and fever associated with the disease.
 Acetaminophen (paracetamol) is
recommended for treatment of pain and fever.

8. NILAVEMBU KUDINEER

9. COMPOSITION OF NILAVEMBU KUDINEER
 Nilavembu (Andrographis paniculata),
 Vilamichu ver (Plectranthus amboinicus),
 Chukku (Zingiber officinale),
 Milagu (Piper nigrum),
 Koraikizhangu (Cyperus rotundus),
 Peipudal (Tricosanthes cucumerina),
 Vettiver (Vettiveria zizanoides),
 Santhanam (Santalum album), and
 Parpadagam (Mollugo cerviana)

10. Nilavembu kudineer preparation
 All the above ingredients are grinded into coarse
powder, called as ‘kudineer choornam’.
 ‘Kudineer choornam’ is then made into kudineer by
adding water and heated, so that the mixture of
kudineer choornam and water reduced to 1/4th or
1/8th of its volume.
 Dose of the kudineer is generally 30ml before food,
three to four times a day.
 Lifetime of prepared kudineer is 1 Samam i.e. 3
hours

11. Nilavembu
(Andrographis paniculata)

12. Vilamichu ver
(Plectranthus amboinicus)

13. Chukku
(Zingiber officinale)

14. Milagu
(Piper nigrum)

15. Koraikizhangu
(Cyperus rotundus)

16. Peipudal
(Tricosanthes cucumerina)

17. Vettiver
(Vettiveria zizanoides)

18. Santhanam
(Santalum album)

19. Parpadagam
(Mollugo cerviana)

20. NILAVEMBU KUDINEER
 All these plants are used traditionally in the treatment of
fever, inflammation, arthralgia, arthritis, gastric ulcer,
jaundice and general debility conditions.
 Nilavembu kudineer controls fever through its healing
effects of temperature regulation, inflammation control
and body pain relief
 It boost the immunity

21. ANDROGRAPHOLIDE
 The medicinal value of this plant is due to the
presence of a bitter active ingredient
andrographolide.
 Andrographolide is a colourless crystalline solid
with bitter taste
 It is a bicyclic diterpenoid lactone derivative, a main
phytochemical compound.
 Other constituents are neoandrographolide, 14-
deoxyandrographolide, and 14-deoxy-11, 12-
didehydro andro-grapholide.

22. CONCLUSION
 Polyherbal preparations like nilavembu kudineer
have excellent antiviral activity against dengue virus
and are less toxic in contrast to the synthetic drugs,
which are regarded as perilous to human being and
environment.

23. Thank you