This document provides information on neuromuscular disorders and the nervous system. It discusses the basic structure and function of neurons, nerves, and muscles. It describes the somatic motor and sensory systems, including reflex activity. It also covers the autonomic nervous system and peripheral nerves. Key aspects of skeletal muscle such as fiber types, contraction, and wasting are summarized. The document concludes with sections on clinical assessment, including history, examination techniques, imaging, and neurophysiological studies.
Muscle spindles are proprioceptors that consist of intrafusal muscle fibers enclosed in a sheath (spindle). They run parallel to the extrafusal muscle fibers and act as receptors that provide information on muscle length and the rate of change in muscle length. The spindles are stretched when the muscle lengthens. This stretch causes the sensory neuron in the spindle to transmit an impulse to the spinal cord, where it synapses with alpha motor neurons. This causes activation of motor neurons that innervate the muscle. The muscle spindles determine the amount of contraction necessary to overcome a given resistance. When the resistance increases, the muscle is stretched further, and this causes spindle fibers to activate a greater muscle contraction.
1. The document discusses the structure and function of skeletal muscle, including the microscopic structure of sarcomeres and how they facilitate muscle contraction via the sliding filament model.
2. It also describes how motor neurons initiate muscle contraction through the transmission of action potentials and release of acetylcholine, triggering the release of calcium ions and cross-bridge cycling of actin and myosin fibers.
3. The types of muscle contractions - isometric, concentric, and eccentric - are defined based on whether muscle tension is generated with or without a change in length.
Nerve fibers can be classified in six different ways: by structure, distribution, origin, function, neurotransmitter secretion, and diameter/impulse conduction. By structure, they are myelinated or non-myelinated. By distribution, they are somatic or autonomic. By origin, they are cranial or spinal. By function, they are sensory or motor. By neurotransmitter, they are adrenergic or cholinergic. By diameter/impulse conduction, Erlanger and Gasser classified them as type A, B, or C fibers with different speeds and functions.
1) The document discusses the knee jerk reflex and stretch reflex, which are monosynaptic reflexes involving the muscle spindle.
2) The muscle spindle contains intrafusal fibers that act as proprioceptors. Primary and secondary endings in the muscle spindle sense changes in muscle length and relay signals to the spinal cord.
3) The stretch reflex arc involves muscle spindles sensing stretch and activating alpha motor neurons, causing contraction of the same muscle and opposing the stretch. This reflex helps maintain muscle tone and posture.
Skeletal muscle cells (myocytes) form long, cylindrical, multinucleated fibers that contract to generate movement. Each fiber contains bundled myofibrils composed of actin and myosin filaments. Nerve impulses trigger calcium release from the sarcoplasmic reticulum, allowing myosin heads to attach to actin and generate force as they detach due to ATP hydrolysis, shortening the sarcomere. Muscle relaxation occurs when calcium is resequestered in the sarcoplasmic reticulum, detaching actin and myosin.
The muscular system allows vertebrates to move through skeletal, cardiac, and smooth muscles. Skeletal muscles are made of striated fibers anchored by tendons containing myofibrils and sarcomeres. At rest, the body produces ATP aerobically without fatigue byproducts, while anaerobic activities produce lactic acid. Cardiac muscles are laterally connected and involuntary. Smooth muscles are involuntary and controlled by the autonomic nervous system, unlike skeletal muscles which are controlled through motor neurons that release acetylcholine at neuromuscular junctions to contract motor units.
1. A motor unit consists of a single alpha motor neuron and the muscle fibers it innervates. Motor units allow for graded muscle contraction and varying degrees of muscle force and precision of movement.
2. Gamma motor neurons innervate muscle spindle fibers, called intrafusal fibers, found within muscle spindles. Muscle spindles contain sensory receptors that provide feedback on muscle length and stretch.
3. Contraction of muscle fibers is initiated at the neuromuscular junction where motor neuron axon terminals release acetylcholine, activating receptors on muscle fibers. The sarcoplasmic reticulum then releases calcium ions, triggering the interaction of actin and myosin filaments and muscle contraction.
This document provides information on neuromuscular disorders and the nervous system. It discusses the basic structure and function of neurons, nerves, and muscles. It describes the somatic motor and sensory systems, including reflex activity. It also covers the autonomic nervous system and peripheral nerves. Key aspects of skeletal muscle such as fiber types, contraction, and wasting are summarized. The document concludes with sections on clinical assessment, including history, examination techniques, imaging, and neurophysiological studies.
Muscle spindles are proprioceptors that consist of intrafusal muscle fibers enclosed in a sheath (spindle). They run parallel to the extrafusal muscle fibers and act as receptors that provide information on muscle length and the rate of change in muscle length. The spindles are stretched when the muscle lengthens. This stretch causes the sensory neuron in the spindle to transmit an impulse to the spinal cord, where it synapses with alpha motor neurons. This causes activation of motor neurons that innervate the muscle. The muscle spindles determine the amount of contraction necessary to overcome a given resistance. When the resistance increases, the muscle is stretched further, and this causes spindle fibers to activate a greater muscle contraction.
1. The document discusses the structure and function of skeletal muscle, including the microscopic structure of sarcomeres and how they facilitate muscle contraction via the sliding filament model.
2. It also describes how motor neurons initiate muscle contraction through the transmission of action potentials and release of acetylcholine, triggering the release of calcium ions and cross-bridge cycling of actin and myosin fibers.
3. The types of muscle contractions - isometric, concentric, and eccentric - are defined based on whether muscle tension is generated with or without a change in length.
Nerve fibers can be classified in six different ways: by structure, distribution, origin, function, neurotransmitter secretion, and diameter/impulse conduction. By structure, they are myelinated or non-myelinated. By distribution, they are somatic or autonomic. By origin, they are cranial or spinal. By function, they are sensory or motor. By neurotransmitter, they are adrenergic or cholinergic. By diameter/impulse conduction, Erlanger and Gasser classified them as type A, B, or C fibers with different speeds and functions.
1) The document discusses the knee jerk reflex and stretch reflex, which are monosynaptic reflexes involving the muscle spindle.
2) The muscle spindle contains intrafusal fibers that act as proprioceptors. Primary and secondary endings in the muscle spindle sense changes in muscle length and relay signals to the spinal cord.
3) The stretch reflex arc involves muscle spindles sensing stretch and activating alpha motor neurons, causing contraction of the same muscle and opposing the stretch. This reflex helps maintain muscle tone and posture.
Skeletal muscle cells (myocytes) form long, cylindrical, multinucleated fibers that contract to generate movement. Each fiber contains bundled myofibrils composed of actin and myosin filaments. Nerve impulses trigger calcium release from the sarcoplasmic reticulum, allowing myosin heads to attach to actin and generate force as they detach due to ATP hydrolysis, shortening the sarcomere. Muscle relaxation occurs when calcium is resequestered in the sarcoplasmic reticulum, detaching actin and myosin.
The muscular system allows vertebrates to move through skeletal, cardiac, and smooth muscles. Skeletal muscles are made of striated fibers anchored by tendons containing myofibrils and sarcomeres. At rest, the body produces ATP aerobically without fatigue byproducts, while anaerobic activities produce lactic acid. Cardiac muscles are laterally connected and involuntary. Smooth muscles are involuntary and controlled by the autonomic nervous system, unlike skeletal muscles which are controlled through motor neurons that release acetylcholine at neuromuscular junctions to contract motor units.
1. A motor unit consists of a single alpha motor neuron and the muscle fibers it innervates. Motor units allow for graded muscle contraction and varying degrees of muscle force and precision of movement.
2. Gamma motor neurons innervate muscle spindle fibers, called intrafusal fibers, found within muscle spindles. Muscle spindles contain sensory receptors that provide feedback on muscle length and stretch.
3. Contraction of muscle fibers is initiated at the neuromuscular junction where motor neuron axon terminals release acetylcholine, activating receptors on muscle fibers. The sarcoplasmic reticulum then releases calcium ions, triggering the interaction of actin and myosin filaments and muscle contraction.
This document summarizes the physiology of the spinal cord. It discusses how the spinal cord integrates sensory information and controls muscle function through reflexes like the stretch reflex and Golgi tendon reflex. It also describes how the brain provides commands to control sequential spinal cord activities for complex movements. The organization of the spinal cord gray matter and types of neurons like anterior motor neurons and interneurons are outlined. Finally, it discusses the roles of muscle spindles and Golgi tendon organs in providing sensory feedback and examples of spinal reflexes.
This document provides an overview of muscle tissue and organization. It discusses the three main types of muscle tissue - skeletal, smooth, and cardiac muscle - and their unique characteristics. Skeletal muscle is striated and voluntary, allowing for movement. It accounts for the majority of muscle in the body. Smooth muscle is involuntary and found within organs and blood vessels. Cardiac muscle is striated and located only in the heart, where it provides rhythmic contractions. The document also covers muscle fiber structure, motor units, and the all-or-none principle of skeletal muscle contraction.
1. Skeletal muscle is composed of bundles of muscle fibers surrounded by connective tissue layers.
2. Each muscle fiber contains protein filaments that slide past each other when stimulated, causing contraction.
3. Motor neurons connect to muscle fibers at neuromuscular junctions and release neurotransmitters that stimulate contraction when an impulse is received from the brain or spinal cord.
The nervous system controls and regulates all body functions and activity through electrical and chemical signals. It has two main parts - the central nervous system (CNS) comprising the brain and spinal cord, and the peripheral nervous system (PNS) comprising nerves throughout the body. The nervous system works with the endocrine system to maintain homeostasis. It receives sensory input from the body and environment via sensory neurons, processes the information in the CNS, and responds by activating muscles and glands through motor neurons.
skeletal, cardiac & smooth Muscles by Thiru Murugan.pptxthiru murugan
Unit III – The Muscular System - Anatomy
Types and structure of muscles
Muscle groups
Alterations in disease
Applications and implications in nursing
Muscle:
Muscle is a soft tissue and it is one of the 4 basic tissues, along with nervous tissue, epithelium, and connective tissue.
Muscles helps in movement, support and protection of internal organs.
Muscles can perform variety of functions
Muscles tissue is made up of cells called “MYOCYTES” or muscle fibers.
There are more than 600 muscles in the human body. A kind of elastic tissue makes up each muscle, which consists of thousands, or tens of thousands, of small muscle fibers.
Types of Muscles: There are 3 main types of muscles
Skeletal muscle
Cardiac muscle
Smooth muscle
Skeletal muscle:
These are having close relationship to the bone or skeleton, so called Skeletal muscles
It present in limbs and related body parts & It form about 40% of body weight.
Under microscope the skeletal muscles fibers shows prominent striations, so called “Striated Muscles” & It is also known as “Voluntary Muscles” (movements are under our control)
Structure of Skeletal muscle:
Muscle fibers shows transverse striations under light microscope so it is called “striated muscles”
The nucleus is located peripherally.
Each skeletal muscle is an organ that consists of numerous cells called muscle fibers.
Each muscle fibers surrounded by “ Endomysium”
Inside each skeletal muscle, muscle fibers are organized into bundles, called fascicles, each fascicle surrounded by perimysium.
The whole muscle is covered by “epimysium”
Each skeletal muscle has three layers: endomysium, perimysium and epimysium
Muscle fibers:
Muscle is composed of many long cylindrical-shaped elongated fibres called muscle fibers
Length varies according to the size and shape of the muscles.
The actual arrangement of the fibres depending on the function of the muscle.
Each muscle fibers covered by a membrane is called the sarcolemma.
The cytoplasm of a muscle fiber is called Sarcoplasm
In sarcoplasm there are many mitochondria and bundles of fine longitudinal thread like part is called “myofibrils”
Microscopic structure of myofibrils:
A myofibril (also known as a muscle fibril or sarcostyle) is a basic rod-like part of a muscle cell.
Muscles are composed of tubular cells called myocytes, known as muscle fibres in striated muscle, and these cells in turn contain many chains of myofibrils.
They are created during embryonic development in a process known as myogenesis.
Under light microscope each myofibril consist of 2 bands:
Light band or “I” Band and Dark band or “A” Band
The alternating pattern of these bands results in the striated appearance of skeletal muscle.
Light band or “I” Band:
The I-bands (isotropic in polarized light) appear light in color.
I band divided into 2 portions by a narrow dark line called “Z” line or “Z” Disc.
This “Z” line is formed by protein which does not permit the light.
The part in between 2 “Z” lines called “sarc
The document summarizes the key components and functions of the muscular system. It discusses the three main types of muscle tissue - skeletal, smooth and cardiac muscle. It describes the structure of skeletal muscle fibers and how they appear striated due to the arrangement of actin and myosin filaments. It explains how a motor neuron stimulation leads to calcium release and the sliding of actin and myosin filaments, causing muscle contraction. Finally, it discusses factors that influence muscle fatigue and responses like threshold stimulus, all-or-none response, and muscle tone.
The nervous system controls and regulates all body functions through sensory and motor nerves that connect the central nervous system to the rest of the body. Sensory nerves transmit impulses from receptors to the CNS, while motor nerves transmit impulses from the CNS to effectors like muscles. The CNS continuously receives sensory input about the environment and responds by issuing motor commands to adjust the body. The nervous system is divided into the central nervous system (brain and spinal cord) and peripheral nervous system (nerves connecting the CNS to the rest of the body). Nervous tissue contains neurons, which transmit signals, and neuroglia, which support neurons. Reflex arcs are the basic functional units of the nervous system and involve
This document summarizes the main types of muscles in the human body. It describes three main types: smooth muscles which line organs and provide motility for digestion; cardiac muscles which make up the heart and contract rhythmically; and skeletal muscles which are striated and allow voluntary movement when stimulated by the nervous system. The functional unit of skeletal muscle is the sarcomere, made up of overlapping thin and thick filaments that slide past each other to cause muscle contraction.
General Physiology - Motor Functions of the Spinal Cord; the Cord ReflexesHamzeh AlBattikhi
The spinal cord contains neurons that control motor functions and reflexes. There are anterior motor neurons that innervate skeletal muscles, and interneurons that connect motor neurons. The cord contains reflex circuits mediated by propriospinal fibers and interneurons. Sensory receptors like muscle spindles and Golgi tendon organs detect changes in muscle length and tension, eliciting stretch and withdrawal reflexes. Spinal cord lesions initially cause spinal shock and loss of reflexes, which gradually recover over weeks.
The nervous system is divided into the central nervous system (CNS) and peripheral nervous system (PNS). The CNS contains the brain and spinal cord, which receive sensory input, integrate information, and respond through motor output. The PNS includes the somatic and autonomic nervous systems. The somatic system connects the CNS to skeletal muscles and senses, while the autonomic system regulates involuntary functions through its sympathetic and parasympathetic divisions. Neurons are the basic functional units that conduct electrical signals, while neuroglia provide support and insulation to neurons.
The document summarizes the organization and function of skeletal muscle. It discusses how:
1) Skeletal muscle fibers are organized into motor units, each innervated by a single motor neuron. Contraction is initiated by motor neuron action potentials triggering muscle fiber action potentials.
2) Muscle fibers contain sarcomeres, the basic contractile units composed of overlapping thin and thick filaments. Cyclical attachment of myosin cross-bridges to actin pulls thin filaments, shortening sarcomeres.
3) Noncontractile elements like connectin filaments and connective tissue transmit force and maintain fiber alignment during contraction and stretching.
Anatomy-Nervous-System Anatomy and Physiology updated.pptxJRRolfNeuqelet
The nervous system is made up of neurons and neuroglia. Neurons transmit signals as electrical impulses between parts of the body, while neuroglia support and protect neurons. There are two main cell types - neurons, which generate and transmit nerve impulses, and neuroglia, which provide nutrients and insulation. The nervous system coordinates activities through neuronal communication via electrical and chemical signals at synapses to allow for reflexes and voluntary control of the body.
This document discusses connective tissue and nervous tissue. It describes the different types of connective tissues, including areolar, adipose, bone, and cartilage tissue. Areolar tissue fills gaps and aids repair. Adipose tissue provides insulation and cushioning. Bone forms the skeletal system and cartilage is present at bone joints. The document then discusses nervous tissue, which consists of neurons and glial cells. Nervous tissue forms the central and peripheral nervous systems and is responsible for monitoring and regulating bodily functions through the transmission of nerve impulses. Key parts of neurons include the cell body, dendrites, axon and synapses.
The nervous system is divided into the central nervous system (CNS) and peripheral nervous system (PNS). The CNS includes the brain and spinal cord, while the PNS includes nerves that connect the CNS to sensory receptors and effectors throughout the body. Neurons are the basic functional units that transmit nerve impulses and include dendrites, a cell body, and an axon. Neuroglia provide support to neurons. The PNS includes spinal and cranial nerves, with different types serving sensory, motor, or integrative functions.
This document discusses the structure, properties, and functions of three main types of muscle tissues - skeletal muscle, cardiac muscle, and smooth muscle. It covers their microscopic structures, nerve supply, location in the body, and roles. The document also explores the implications of understanding the muscular system for nursing practice, such as in patient assessment, care planning, and prevention of injuries.
Nervous tissue is specialized tissue that reacts to stimuli and conducts impulses throughout the body. It is composed of neurons, which are nerve cells that transmit signals rapidly. There are three main types of neurons: sensory neurons that relay signals from senses to the central nervous system, motor neurons that transmit signals from the central nervous system to organs, and interneurons that connect sensory and motor neurons. Neuroglial cells provide support and protection for neurons. Nervous tissue allows organisms to sense the environment and make coordinated responses through the conduction of signals via these different types of neurons.
The document describes the structure and function of the nervous system. It discusses how the nervous system can be divided structurally into the central nervous system (CNS) and peripheral nervous system (PNS), and functionally into the sensory and motor divisions. Neurons are the basic functional units that initiate and transmit nerve impulses, while glial cells provide support and protection. The document provides details on the anatomy and classifications of neurons, glial cells, nerves, and synapses.
The nervous system controls and regulates all activities of the body. It is divided into the central nervous system and peripheral nervous system. The central nervous system includes the brain and spinal cord, which contain governing centers that receive sensory input and issue motor commands. The peripheral nervous system includes nerves that connect the central nervous system to the rest of the body, allowing it to receive sensory information and direct motor functions in organs, muscles and glands. Together, the nervous system allows the body to respond to its external environment and maintain internal stability.
The document summarizes the basic structure and function of the nervous system. It is divided into the central nervous system (CNS), which contains the brain and spinal cord, and the peripheral nervous system (PNS), which includes cranial and spinal nerves. The PNS has two divisions - the somatic nervous system, which controls voluntary skeletal muscles and relays sensory information, and the autonomic nervous system, which controls involuntary functions like digestion. The autonomic nervous system has two branches - the sympathetic branch which prepares the body for stress, and the parasympathetic branch which maintains normal functions at rest. Neurons are the basic functional units that receive, conduct and connect information, while glia provide neurons with support.
- Video recording of this lecture in English language: https://youtu.be/Pt1nA32sdHQ
- Video recording of this lecture in Arabic language: https://youtu.be/uFdc9F0rlP0
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
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This document summarizes the physiology of the spinal cord. It discusses how the spinal cord integrates sensory information and controls muscle function through reflexes like the stretch reflex and Golgi tendon reflex. It also describes how the brain provides commands to control sequential spinal cord activities for complex movements. The organization of the spinal cord gray matter and types of neurons like anterior motor neurons and interneurons are outlined. Finally, it discusses the roles of muscle spindles and Golgi tendon organs in providing sensory feedback and examples of spinal reflexes.
This document provides an overview of muscle tissue and organization. It discusses the three main types of muscle tissue - skeletal, smooth, and cardiac muscle - and their unique characteristics. Skeletal muscle is striated and voluntary, allowing for movement. It accounts for the majority of muscle in the body. Smooth muscle is involuntary and found within organs and blood vessels. Cardiac muscle is striated and located only in the heart, where it provides rhythmic contractions. The document also covers muscle fiber structure, motor units, and the all-or-none principle of skeletal muscle contraction.
1. Skeletal muscle is composed of bundles of muscle fibers surrounded by connective tissue layers.
2. Each muscle fiber contains protein filaments that slide past each other when stimulated, causing contraction.
3. Motor neurons connect to muscle fibers at neuromuscular junctions and release neurotransmitters that stimulate contraction when an impulse is received from the brain or spinal cord.
The nervous system controls and regulates all body functions and activity through electrical and chemical signals. It has two main parts - the central nervous system (CNS) comprising the brain and spinal cord, and the peripheral nervous system (PNS) comprising nerves throughout the body. The nervous system works with the endocrine system to maintain homeostasis. It receives sensory input from the body and environment via sensory neurons, processes the information in the CNS, and responds by activating muscles and glands through motor neurons.
skeletal, cardiac & smooth Muscles by Thiru Murugan.pptxthiru murugan
Unit III – The Muscular System - Anatomy
Types and structure of muscles
Muscle groups
Alterations in disease
Applications and implications in nursing
Muscle:
Muscle is a soft tissue and it is one of the 4 basic tissues, along with nervous tissue, epithelium, and connective tissue.
Muscles helps in movement, support and protection of internal organs.
Muscles can perform variety of functions
Muscles tissue is made up of cells called “MYOCYTES” or muscle fibers.
There are more than 600 muscles in the human body. A kind of elastic tissue makes up each muscle, which consists of thousands, or tens of thousands, of small muscle fibers.
Types of Muscles: There are 3 main types of muscles
Skeletal muscle
Cardiac muscle
Smooth muscle
Skeletal muscle:
These are having close relationship to the bone or skeleton, so called Skeletal muscles
It present in limbs and related body parts & It form about 40% of body weight.
Under microscope the skeletal muscles fibers shows prominent striations, so called “Striated Muscles” & It is also known as “Voluntary Muscles” (movements are under our control)
Structure of Skeletal muscle:
Muscle fibers shows transverse striations under light microscope so it is called “striated muscles”
The nucleus is located peripherally.
Each skeletal muscle is an organ that consists of numerous cells called muscle fibers.
Each muscle fibers surrounded by “ Endomysium”
Inside each skeletal muscle, muscle fibers are organized into bundles, called fascicles, each fascicle surrounded by perimysium.
The whole muscle is covered by “epimysium”
Each skeletal muscle has three layers: endomysium, perimysium and epimysium
Muscle fibers:
Muscle is composed of many long cylindrical-shaped elongated fibres called muscle fibers
Length varies according to the size and shape of the muscles.
The actual arrangement of the fibres depending on the function of the muscle.
Each muscle fibers covered by a membrane is called the sarcolemma.
The cytoplasm of a muscle fiber is called Sarcoplasm
In sarcoplasm there are many mitochondria and bundles of fine longitudinal thread like part is called “myofibrils”
Microscopic structure of myofibrils:
A myofibril (also known as a muscle fibril or sarcostyle) is a basic rod-like part of a muscle cell.
Muscles are composed of tubular cells called myocytes, known as muscle fibres in striated muscle, and these cells in turn contain many chains of myofibrils.
They are created during embryonic development in a process known as myogenesis.
Under light microscope each myofibril consist of 2 bands:
Light band or “I” Band and Dark band or “A” Band
The alternating pattern of these bands results in the striated appearance of skeletal muscle.
Light band or “I” Band:
The I-bands (isotropic in polarized light) appear light in color.
I band divided into 2 portions by a narrow dark line called “Z” line or “Z” Disc.
This “Z” line is formed by protein which does not permit the light.
The part in between 2 “Z” lines called “sarc
The document summarizes the key components and functions of the muscular system. It discusses the three main types of muscle tissue - skeletal, smooth and cardiac muscle. It describes the structure of skeletal muscle fibers and how they appear striated due to the arrangement of actin and myosin filaments. It explains how a motor neuron stimulation leads to calcium release and the sliding of actin and myosin filaments, causing muscle contraction. Finally, it discusses factors that influence muscle fatigue and responses like threshold stimulus, all-or-none response, and muscle tone.
The nervous system controls and regulates all body functions through sensory and motor nerves that connect the central nervous system to the rest of the body. Sensory nerves transmit impulses from receptors to the CNS, while motor nerves transmit impulses from the CNS to effectors like muscles. The CNS continuously receives sensory input about the environment and responds by issuing motor commands to adjust the body. The nervous system is divided into the central nervous system (brain and spinal cord) and peripheral nervous system (nerves connecting the CNS to the rest of the body). Nervous tissue contains neurons, which transmit signals, and neuroglia, which support neurons. Reflex arcs are the basic functional units of the nervous system and involve
This document summarizes the main types of muscles in the human body. It describes three main types: smooth muscles which line organs and provide motility for digestion; cardiac muscles which make up the heart and contract rhythmically; and skeletal muscles which are striated and allow voluntary movement when stimulated by the nervous system. The functional unit of skeletal muscle is the sarcomere, made up of overlapping thin and thick filaments that slide past each other to cause muscle contraction.
General Physiology - Motor Functions of the Spinal Cord; the Cord ReflexesHamzeh AlBattikhi
The spinal cord contains neurons that control motor functions and reflexes. There are anterior motor neurons that innervate skeletal muscles, and interneurons that connect motor neurons. The cord contains reflex circuits mediated by propriospinal fibers and interneurons. Sensory receptors like muscle spindles and Golgi tendon organs detect changes in muscle length and tension, eliciting stretch and withdrawal reflexes. Spinal cord lesions initially cause spinal shock and loss of reflexes, which gradually recover over weeks.
The nervous system is divided into the central nervous system (CNS) and peripheral nervous system (PNS). The CNS contains the brain and spinal cord, which receive sensory input, integrate information, and respond through motor output. The PNS includes the somatic and autonomic nervous systems. The somatic system connects the CNS to skeletal muscles and senses, while the autonomic system regulates involuntary functions through its sympathetic and parasympathetic divisions. Neurons are the basic functional units that conduct electrical signals, while neuroglia provide support and insulation to neurons.
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1) Skeletal muscle fibers are organized into motor units, each innervated by a single motor neuron. Contraction is initiated by motor neuron action potentials triggering muscle fiber action potentials.
2) Muscle fibers contain sarcomeres, the basic contractile units composed of overlapping thin and thick filaments. Cyclical attachment of myosin cross-bridges to actin pulls thin filaments, shortening sarcomeres.
3) Noncontractile elements like connectin filaments and connective tissue transmit force and maintain fiber alignment during contraction and stretching.
Anatomy-Nervous-System Anatomy and Physiology updated.pptxJRRolfNeuqelet
The nervous system is made up of neurons and neuroglia. Neurons transmit signals as electrical impulses between parts of the body, while neuroglia support and protect neurons. There are two main cell types - neurons, which generate and transmit nerve impulses, and neuroglia, which provide nutrients and insulation. The nervous system coordinates activities through neuronal communication via electrical and chemical signals at synapses to allow for reflexes and voluntary control of the body.
This document discusses connective tissue and nervous tissue. It describes the different types of connective tissues, including areolar, adipose, bone, and cartilage tissue. Areolar tissue fills gaps and aids repair. Adipose tissue provides insulation and cushioning. Bone forms the skeletal system and cartilage is present at bone joints. The document then discusses nervous tissue, which consists of neurons and glial cells. Nervous tissue forms the central and peripheral nervous systems and is responsible for monitoring and regulating bodily functions through the transmission of nerve impulses. Key parts of neurons include the cell body, dendrites, axon and synapses.
The nervous system is divided into the central nervous system (CNS) and peripheral nervous system (PNS). The CNS includes the brain and spinal cord, while the PNS includes nerves that connect the CNS to sensory receptors and effectors throughout the body. Neurons are the basic functional units that transmit nerve impulses and include dendrites, a cell body, and an axon. Neuroglia provide support to neurons. The PNS includes spinal and cranial nerves, with different types serving sensory, motor, or integrative functions.
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Nervous tissue is specialized tissue that reacts to stimuli and conducts impulses throughout the body. It is composed of neurons, which are nerve cells that transmit signals rapidly. There are three main types of neurons: sensory neurons that relay signals from senses to the central nervous system, motor neurons that transmit signals from the central nervous system to organs, and interneurons that connect sensory and motor neurons. Neuroglial cells provide support and protection for neurons. Nervous tissue allows organisms to sense the environment and make coordinated responses through the conduction of signals via these different types of neurons.
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The nervous system controls and regulates all activities of the body. It is divided into the central nervous system and peripheral nervous system. The central nervous system includes the brain and spinal cord, which contain governing centers that receive sensory input and issue motor commands. The peripheral nervous system includes nerves that connect the central nervous system to the rest of the body, allowing it to receive sensory information and direct motor functions in organs, muscles and glands. Together, the nervous system allows the body to respond to its external environment and maintain internal stability.
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Travel Clinic Cardiff offers comprehensive travel health services, including vaccinations, travel advice, and preventive care for international travelers. Our expert team ensures you are well-prepared and protected for your journey, providing personalized consultations tailored to your destination. Conveniently located in Cardiff, we help you travel with confidence and peace of mind. Visit us: www.nxhealthcare.co.uk
Travel vaccination in Manchester offers comprehensive immunization services for individuals planning international trips. Expert healthcare providers administer vaccines tailored to your destination, ensuring you stay protected against various diseases. Conveniently located clinics and flexible appointment options make it easy to get the necessary shots before your journey. Stay healthy and travel with confidence by getting vaccinated in Manchester. Visit us: www.nxhealthcare.co.uk
How to Control Your Asthma Tips by gokuldas hospital.Gokuldas Hospital
Respiratory issues like asthma are the most sensitive issue that is affecting millions worldwide. It hampers the daily activities leaving the body tired and breathless.
The key to a good grip on asthma is proper knowledge and management strategies. Understanding the patient-specific symptoms and carving out an effective treatment likewise is the best way to keep asthma under control.
DECLARATION OF HELSINKI - History and principlesanaghabharat01
This SlideShare presentation provides a comprehensive overview of the Declaration of Helsinki, a foundational document outlining ethical guidelines for conducting medical research involving human subjects.
5-hydroxytryptamine or 5-HT or Serotonin is a neurotransmitter that serves a range of roles in the human body. It is sometimes referred to as the happy chemical since it promotes overall well-being and happiness.
It is mostly found in the brain, intestines, and blood platelets.
5-HT is utilised to transport messages between nerve cells, is known to be involved in smooth muscle contraction, and adds to overall well-being and pleasure, among other benefits. 5-HT regulates the body's sleep-wake cycles and internal clock by acting as a precursor to melatonin.
It is hypothesised to regulate hunger, emotions, motor, cognitive, and autonomic processes.
These lecture slides, by Dr Sidra Arshad, offer a simplified look into the mechanisms involved in the regulation of respiration:
Learning objectives:
1. Describe the organisation of respiratory center
2. Describe the nervous control of inspiration and respiratory rhythm
3. Describe the functions of the dorsal and respiratory groups of neurons
4. Describe the influences of the Pneumotaxic and Apneustic centers
5. Explain the role of Hering-Breur inflation reflex in regulation of inspiration
6. Explain the role of central chemoreceptors in regulation of respiration
7. Explain the role of peripheral chemoreceptors in regulation of respiration
8. Explain the regulation of respiration during exercise
9. Integrate the respiratory regulatory mechanisms
10. Describe the Cheyne-Stokes breathing
Study Resources:
1. Chapter 42, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 36, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 13, Human Physiology by Lauralee Sherwood, 9th edition
3. NERVE SUPPLY OF SKELETAL MUSCLE
The nerve supplying a muscle is called motor
nerve.
In fact it is a mixed nerve and consists of the
following types of fibres.
Motor Fibers 60 %
Sensory Fibers 40%
4.
5. .Motor fibres (60%) comprise:
(a) Large myelinated alpha efferents which supply
extrafusal muscle fibres
(b) Smaller myelinated gamma efferents which supply
intrafusal fibres of the muscle spindles which refine and
control muscle contraction.
(c) The fine non-myelinated autonomic efferents which
supply smooth muscle fibres of the blood vessels.
6.
7. .Sensory fibres (40%) comprise:
Myelinated fibres distributed to muscle spindles for
proprioception, also to tendons.
Muscle spindles are spindle-shaped sensory end
organs of the skeletal muscle.
Each spindle contains 6-14 intrafusal muscle fibres
Muscles
which are of two types, the larger nuclear bag
fibres, and the smaller nuclear chain fibres
8.
9. NERVE SUPLY TO SPINDLE
The spindle is innervated by both the
sensory and motor nerves. The sensory
endings are of two types, the primary
sensory endings (annulospiral endings)
around the central nuclear region of the
intrafusal fibres, and the secondary sensory
endings (flower spray endings) beyond the
nuclear region on either side of these fibres.
10. Motor point
It is the site where the motor nerve enters
the muscle. It may be one or more than
one. Electrical stimulation at the motor
point is more effective
11. Motor unit (myone)
It is defined as a single alpha motor neuron together with the
muscle fibres supplied by it. The size of motor unit depends
upon the precision of muscle control.
Small motor units (5-10 muscle fibres) are found in muscles of
fine movements (extraocular muscles).
Large motor units (100-2000 muscle fibres) are found in
muscles of gross movements (proximal limb muscles).
12. Composite/hybrid muscle:
Muscle supplied by two different motor nerves
with different root values is called a composite or
hybrid muscle,
e.g. adductor magnus, flexor digitorum profundus
and pectoralis major.
13.
14. Nerve Supply of Smooth Muscle
According to nerve supply the smooth muscles are classified into:
Single-unit type:
Seen in intestines. The nerve impulse reaches one muscle cell, is
transmitted to other cells by the mechanical pull through the fused
cell membrane. The nerve supply is sparse.
Multi-unit type:
Seen in the muscles of the ductus deferens. Each muscle cell receives
a separate nerve fibre. The contraction is simultaneous. The nerve
supply is rich