The document analyzes debates between scholars ("high counters" vs "low counters") about the timing and impact of epidemics on Native American populations after European contact. It summarizes evidence from primary sources to argue that major epidemics did not reach the Northeast US until the 1616 plague and 1633 epidemics, reducing populations 86-95% rather than in the 16th century as some propose. It also discusses flaws in "high counter" theories and evidence supporting a later arrival of devastating epidemics.