N-isopropyl acrylamide is an acrylamide monomer used to produce thermosensitive polymers and hydrogels. It has the ability to change its properties based on temperature, shrinking dramatically above 33°C. It is used in various applications including drug delivery, tissue engineering, sensors, and more. Poly(N-isopropyl acrylamide) has a lower critical solution temperature of 31-33°C and can be synthesized from N-isopropyl acrylamide via free radical polymerization.
APPLICATIONS OF PLA - POLY (LACTIC ACID) IN TISSUE ENGINEERING AND DELIVERY S...Ana Rita Ramos
Poly (lactic acid) is a thermoplastic derived from renewable resources and is at present, one of the most promising biodegradable and nontoxic biopolymers. In addition to its versatility and consequent large-scale production, PLA can be processed with a large number of techniques.
Due to its excellent mechanical properties and biocompatibility, this polymer is becoming largely applied in the biomedical field such as in tissue engineering for scaffolds and in delivery systems in the form of micro and nanoparticles. Furthermore, because it’s relatively cheap and an eco-friend, it has been considered as one of the solutions to lessen the dependence on petroleum-based plastics and solid waste problems.
In order to maximize the knowledge and development of this polymer, it is necessary to understand the material synthesis, proprieties, manufacturing processes, main applications, commercialization and its market state, which will be presented in this review.
1. Introduction
2. Poly (lactic acid)
2.1. Precursors
2.2. Synthesis
2.3. Proprieties
2.4. Processing
2.5. Biomedical Applications
2.6. Other Applications
3. Economic Potential of PLA
4. Conclusions
Nhận viết luận văn Đại học , thạc sĩ - Zalo: 0917.193.864
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APPLICATIONS OF PLA - POLY (LACTIC ACID) IN TISSUE ENGINEERING AND DELIVERY S...Ana Rita Ramos
Poly (lactic acid) is a thermoplastic derived from renewable resources and is at present, one of the most promising biodegradable and nontoxic biopolymers. In addition to its versatility and consequent large-scale production, PLA can be processed with a large number of techniques.
Due to its excellent mechanical properties and biocompatibility, this polymer is becoming largely applied in the biomedical field such as in tissue engineering for scaffolds and in delivery systems in the form of micro and nanoparticles. Furthermore, because it’s relatively cheap and an eco-friend, it has been considered as one of the solutions to lessen the dependence on petroleum-based plastics and solid waste problems.
In order to maximize the knowledge and development of this polymer, it is necessary to understand the material synthesis, proprieties, manufacturing processes, main applications, commercialization and its market state, which will be presented in this review.
1. Introduction
2. Poly (lactic acid)
2.1. Precursors
2.2. Synthesis
2.3. Proprieties
2.4. Processing
2.5. Biomedical Applications
2.6. Other Applications
3. Economic Potential of PLA
4. Conclusions
Nhận viết luận văn Đại học , thạc sĩ - Zalo: 0917.193.864
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Synthesis and properties of PolyanilineAwad Albalwi
Polyaniline which is regarding kind of Inherently Conducting Polymers (ICPs), was prepared by
either chemical and electricchemical polymerization in acidic medium. Such solvents were used
and compared the affecting on the conductivity between EB solution in DMF and mcresol solvents by using UVvis spectrum. UVvis
spectra and cyclic voltametry were used to generate
and analyze the spectrum for the polymer films
It is described about polymer/clay nanocomposites which can be abbreviated to PCNC, their preparation methods, properties and relevances, important types of polymers employed in the preparation of PCNC, montmorillonite crystal structures,
Download luận án tiến sĩ ngành hóa học với đề tài: Nghiên cứu tổng hợp vật liệu bán dẫn hữu cơ ứng dụng trong lĩnh vực quang điện tử, cho các bạn tham khảo
Nhận viết luận văn đại học, thạc sĩ trọn gói, chất lượng, LH ZALO=>0909232620
Tham khảo dịch vụ, bảng giá tại: https://baocaothuctap.net
Synthesis and properties of PolyanilineAwad Albalwi
Polyaniline which is regarding kind of Inherently Conducting Polymers (ICPs), was prepared by
either chemical and electricchemical polymerization in acidic medium. Such solvents were used
and compared the affecting on the conductivity between EB solution in DMF and mcresol solvents by using UVvis spectrum. UVvis
spectra and cyclic voltametry were used to generate
and analyze the spectrum for the polymer films
It is described about polymer/clay nanocomposites which can be abbreviated to PCNC, their preparation methods, properties and relevances, important types of polymers employed in the preparation of PCNC, montmorillonite crystal structures,
Download luận án tiến sĩ ngành hóa học với đề tài: Nghiên cứu tổng hợp vật liệu bán dẫn hữu cơ ứng dụng trong lĩnh vực quang điện tử, cho các bạn tham khảo
Nhận viết luận văn đại học, thạc sĩ trọn gói, chất lượng, LH ZALO=>0909232620
Tham khảo dịch vụ, bảng giá tại: https://baocaothuctap.net
Ninhydrin Based Visible Spectrophotometric Determination of GemigliptinRatnakaram Venkata Nadh
A simple method is described to determine the amount of gemigliptin in bulk and tablet formulation by visible spectrophotometry. Basis of the proposed method is the reaction of the primary amine present on gemigliptin with ninhydrin in alkaline pH (alkaline borate buffer) medium to produce a purple color (Ruhemann’s purple) which has maximum absorption at 558 nm. The method was validated as per the current ICH guidelines. The obtained regression equation (y = 0.0148x+0.0011) in the range of 5-30 μg mL-1 has a good correlation coefficient (> 0.999). As the method does not require any separation, it is rapid and simple. The recovery levels of the drug were in the range of 99.73 – 99.96. This method is a green method as it no organic solvents were employed
Ninhydrin Based Visible Spectrophotometric Determination of GemigliptinRatnakaram Venkata Nadh
A simple method is described to determine the amount of gemigliptin in bulk and tablet formulation by visible spectrophotometry. Basis of the proposed method is the reaction of the primary amine present on gemigliptin with ninhydrin in alkaline pH (alkaline borate buffer) medium to produce a purple color (Ruhemann’s purple) which has maximum absorption at 558 nm. The method was validated as per the current ICH guidelines. The obtained regression equation (y = 0.0148x+0.0011) in the range of 5-30 μg mL-1 has a good correlation coefficient (> 0.999). As the method does not require any separation, it is rapid and simple. The recovery levels of the drug were in the range of 99.73 – 99.96. This method is a green method as it no organic solvents were employed
Synthesis and Anti-Inflammatory activity of Sulpha/substituted 1,2-Diazolesinventionjournals
A Novel compound namely N1 (3 Nicotinoyl) 3,5 dimethyl-4-(N-4-sulfamoyl-azo)-1,2-diazoles has been synthesized by two step processes. Synthesis of N1 -4-sulfamoylphenylhydrazono-3,5-dimethyl propane-1,3-dione and sulfonamide, which interacting with 3-Nicotinoyl hydrazine to form final compound. The newly synthesized compound N1 -(3-Nicotinoyl)-3,5-dimethyl 4-(N1 -4-sulfamoyl phenyl azo) 1,2-diazoles was screened for antiinflammatory activity
Synthesis and Anti-Inflammatory activity of Sulpha/substituted 1,2-Diazolesinventionjournals
A Novel compound namely N1 (3 Nicotinoyl) 3,5 dimethyl-4-(N-4-sulfamoyl-azo)-1,2-diazoles has been synthesized by two step processes. Synthesis of N1 -4-sulfamoylphenylhydrazono-3,5-dimethyl propane-1,3-dione and sulfonamide, which interacting with 3-Nicotinoyl hydrazine to form final compound. The newly synthesized compound N1 -(3-Nicotinoyl)-3,5-dimethyl 4-(N1 -4-sulfamoyl phenyl azo) 1,2-diazoles was screened for antiinflammatory activity
Novel Conductive Nano-composite Ink Based on Poly Aniline, Silver Nanoparticl...Khaled Abdel-Razeq
Novel Conductive Nano-composite Ink Based on Poly Aniline, Silver Nanoparticles and Nitrocellulose
Egypt. J. Chem. 59, No. 4, pp. 429 - 443 (2016)
http://ejchem.js.iknito.com/article_1101.html
In this work a new prodrug polymer was
prepared with two attachment groups (amid-ester), using di
functional spacer such as ethanol amine, which could react with
polyacrylic acid producing amide group, with remain ethanol
terminal group which could react with captopril acyl chloride,
producing ester group with extended the arm substituted drug to
improve the hydrolysis and to prevent the steric effect of polymer
chains. Many advantages enhanced the prodrug of polymer. The
prepared polymers were characterized by FTIR, 1H –NMR
spectroscopies. Controlled drug release was studied in different
pH values at 37℃, using UV. Spectra with comparing with
calibration curve. The modification percentage test was studied,and swelling percentage was calculated and all physical properties were observed.
New Schiff base ligand (E)-6-(2-(4-
(dimethylamino)benzylideneamino)-2-phenylacetamido)-3,3-
dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic
acid = (HL) Figure(1) was prepared via condensation of
Ampicillin and 4(dimethylamino)benzaldehyde in methanol
.Polydentate mixed ligand complexes were obtained from 1:1:2
molar ratio reactions with metal ions and HL, 2NA on reaction
with MCl2 .nH2O salt yields complexes corresponding to the
formulas [M(L)(NA)2Cl] ,where M =
Fe(II),Co(II),Ni(II),Cu(II),and Zn(II) and NA=nicotinamide.
The 1H-NMR, FT-IR, UV-Vis and elemental analysis
were used for the characterization of the ligand. The complexes
were structurally studied through AAS, FT-IR, UV-Vis,
chloride contents, conductance, and magnetic susceptibility
measurements. All complexes are non-electrolytes in DMSO
solution. Octahedral geometries have been suggested for each
of the complexes. The Schiff base ligands function as
tridentates and the deprotonated enolic form is preferred for
coordination. In order to evaluate the effect of the bactericidal
activity, these synthesized complexes, in comparison to the un
complexed Schiff base has been screened against bacterial
species, Staphy
PREPARATION AND IN-VITRO EVALUATION OF ITRACONAZOLE LOADED NANOSPONGES FOR T...Mahewash Sana Pathan
Itraconazole is an imidazole derivative and used for the treatment of local and systemic fungal infections. It is a BCS Class II drug having very low solubility in water i.e. 1-4ng/ml. The oral use of Itraconazole is not much recommended as it has many side effects. The present research has been undertaken with the aim to develop a topical hydrogel formulation of Itraconazole loaded nanosponges to increase the solubility, permeability and stability of itraconazole. Itraconazole loaded nanosponge was prepared by emulsion solvent diffusion method by using different concentrations of ethyl cellulose as a polymer, Polyvinyl alcohol as surfactant and dichloromethane as cross linking agent. Physical characteristics of the nanosponges as well as the drug entrapment efficiency, percentage drug content, Percent yield, drug polymer compatibility, solubility studies of the nanosponges were investigated. Particle size analysis and surface morphology of nanosponges were performed. The scanning electron microscopy of nanosponges showed that they were spherical in shape and spongy in nature. Drug entrapment efficiency was found to be in the range of 42.75 % to 73.10 %. The optimized nanosponge formulation was loaded into hydrogel using carbopol 940 and studied for pH, viscosity, in vitro drug release. Of the nanosponge formulations prepared, F4 was found to show drug release of 70.62%. It was concluded that Itraconazole nanosponge hydrogel may have increased solubility and drug release
In this research in order to produce blood sugar biosensor, an appropriate
membrane for glucose oxidase immobilization by using nanofibers created from
polymers of polyacrylic acid and starch are studied. They are biocompatible and
biodegradable respectively and were prepared by electro-spinning method for
nanofiber fabrication. Dimethylformamide and distilled water were used as solvent for
PAA and starch respectively to get a homogeneous solution. Because nanofibers made
of polyacrylic acid-starch face with enzymes, due to its extremely high hydrophilic
‘OH’ groups may lose their cohesion, crosslinking as chemical surface modification
and for better enzyme immobilization, non-thermal plasma surface modification using
atmospheric pressure Dielectric Barrier Discharge (DBD) were used. Crosslinking was
carried out by APTMS and Glutaraldehyde (GA). The effect of electro-spinning process
variables on morphology of nanofibers was examined by Scanning Electron
Microscopy (SEM). Nanofibers structure and chemical composition to demonstrate
the successful linking and immobilization of enzymes in the composite membrane was
obtained by Fourier Transform Infrared spectroscopy (FTIR) and improved thermal
stability of nanofibers in presence of enzyme and surface modifications was
determined by Thermal Gravimetric Analysis (TGA).
Synthesis, characterisation and antibacterial activity of copolymer (n vinylp...eSAT Publishing House
IJRET : International Journal of Research in Engineering and Technology is an international peer reviewed, online journal published by eSAT Publishing House for the enhancement of research in various disciplines of Engineering and Technology. The aim and scope of the journal is to provide an academic medium and an important reference for the advancement and dissemination of research results that support high-level learning, teaching and research in the fields of Engineering and Technology. We bring together Scientists, Academician, Field Engineers, Scholars and Students of related fields of Engineering and Technology
Synthesis, characterisation and antibacterial activity of copolymer (n vinylp...eSAT Journals
Abstract A copolymer of N-vinylpyrrolidone (NVP) with maleic anhydride (MA) is synthesized by radical copolymerization with 2,2-Azo-bisisobutyronitrile(AIBN) as initiator at 650C in dioxane solution, under nitrogen atmosphere. The copolymer obtained is characterized by FTIR and NMR. The copolymer is made to interact with N,N-Diethylaminoethanol (DEAE) in different ratios. The susceptibility of some Gram - negative bacteria like Klebsiella aerogenes NCIM-2098, Escherichia coli NCIM-5051, Pseudomonasaeruginosa NCIM2242, Pseudomonas desmolyticum NCIM-2028 and a Gram positive bacteria Staphylococcus aureus NCIM-5022, to the copolymer and its compound with N,N-Diethylaminoethanol of different compositions in microbiological medium is studied by Agar well diffusion method. The resulting polymeric antibacterial material is useful in a number of medicines and food industry. Keywords: N-vinylpyrrolidone, Maleic anhydride, Copolymerization, N, N-diethylaminoethanol, FTIR, NMR, Antibacterial activity.
How to Make a Field invisible in Odoo 17Celine George
It is possible to hide or invisible some fields in odoo. Commonly using “invisible” attribute in the field definition to invisible the fields. This slide will show how to make a field invisible in odoo 17.
Students, digital devices and success - Andreas Schleicher - 27 May 2024..pptxEduSkills OECD
Andreas Schleicher presents at the OECD webinar ‘Digital devices in schools: detrimental distraction or secret to success?’ on 27 May 2024. The presentation was based on findings from PISA 2022 results and the webinar helped launch the PISA in Focus ‘Managing screen time: How to protect and equip students against distraction’ https://www.oecd-ilibrary.org/education/managing-screen-time_7c225af4-en and the OECD Education Policy Perspective ‘Students, digital devices and success’ can be found here - https://oe.cd/il/5yV
Synthetic Fiber Construction in lab .pptxPavel ( NSTU)
Synthetic fiber production is a fascinating and complex field that blends chemistry, engineering, and environmental science. By understanding these aspects, students can gain a comprehensive view of synthetic fiber production, its impact on society and the environment, and the potential for future innovations. Synthetic fibers play a crucial role in modern society, impacting various aspects of daily life, industry, and the environment. ynthetic fibers are integral to modern life, offering a range of benefits from cost-effectiveness and versatility to innovative applications and performance characteristics. While they pose environmental challenges, ongoing research and development aim to create more sustainable and eco-friendly alternatives. Understanding the importance of synthetic fibers helps in appreciating their role in the economy, industry, and daily life, while also emphasizing the need for sustainable practices and innovation.
How to Split Bills in the Odoo 17 POS ModuleCeline George
Bills have a main role in point of sale procedure. It will help to track sales, handling payments and giving receipts to customers. Bill splitting also has an important role in POS. For example, If some friends come together for dinner and if they want to divide the bill then it is possible by POS bill splitting. This slide will show how to split bills in odoo 17 POS.
The Roman Empire A Historical Colossus.pdfkaushalkr1407
The Roman Empire, a vast and enduring power, stands as one of history's most remarkable civilizations, leaving an indelible imprint on the world. It emerged from the Roman Republic, transitioning into an imperial powerhouse under the leadership of Augustus Caesar in 27 BCE. This transformation marked the beginning of an era defined by unprecedented territorial expansion, architectural marvels, and profound cultural influence.
The empire's roots lie in the city of Rome, founded, according to legend, by Romulus in 753 BCE. Over centuries, Rome evolved from a small settlement to a formidable republic, characterized by a complex political system with elected officials and checks on power. However, internal strife, class conflicts, and military ambitions paved the way for the end of the Republic. Julius Caesar’s dictatorship and subsequent assassination in 44 BCE created a power vacuum, leading to a civil war. Octavian, later Augustus, emerged victorious, heralding the Roman Empire’s birth.
Under Augustus, the empire experienced the Pax Romana, a 200-year period of relative peace and stability. Augustus reformed the military, established efficient administrative systems, and initiated grand construction projects. The empire's borders expanded, encompassing territories from Britain to Egypt and from Spain to the Euphrates. Roman legions, renowned for their discipline and engineering prowess, secured and maintained these vast territories, building roads, fortifications, and cities that facilitated control and integration.
The Roman Empire’s society was hierarchical, with a rigid class system. At the top were the patricians, wealthy elites who held significant political power. Below them were the plebeians, free citizens with limited political influence, and the vast numbers of slaves who formed the backbone of the economy. The family unit was central, governed by the paterfamilias, the male head who held absolute authority.
Culturally, the Romans were eclectic, absorbing and adapting elements from the civilizations they encountered, particularly the Greeks. Roman art, literature, and philosophy reflected this synthesis, creating a rich cultural tapestry. Latin, the Roman language, became the lingua franca of the Western world, influencing numerous modern languages.
Roman architecture and engineering achievements were monumental. They perfected the arch, vault, and dome, constructing enduring structures like the Colosseum, Pantheon, and aqueducts. These engineering marvels not only showcased Roman ingenuity but also served practical purposes, from public entertainment to water supply.
Model Attribute Check Company Auto PropertyCeline George
In Odoo, the multi-company feature allows you to manage multiple companies within a single Odoo database instance. Each company can have its own configurations while still sharing common resources such as products, customers, and suppliers.
Welcome to TechSoup New Member Orientation and Q&A (May 2024).pdfTechSoup
In this webinar you will learn how your organization can access TechSoup's wide variety of product discount and donation programs. From hardware to software, we'll give you a tour of the tools available to help your nonprofit with productivity, collaboration, financial management, donor tracking, security, and more.
4. N- isopropyl acrylamide is an acrylamide group
monomer used in the preparation of thermally
sensitive, water-swellable hydrogels.
N-Isopropylacrylamide is used to produce poly
(N-isopropylacrylamide) (pNIPA, pNIPAAm, pNIPAA
or pNIPAm) thermo sensitive polymer, water swellable
hydrogels and micelles.
Polymers that contain NIPAM shrink dramatically
above 33°C and may be useful for drug delivery.
Storage Conditions :Keep container tightly closed in a
dry and well-ventilated place.
5. Environmental Fate & Exposure:
□ N-Isopropylacrylamide's production and use as a binder in
textiles, paper adhesives, detergents, cosmetics, and chemical
intermediate in processes such as drug delivery systems and
nanotechnology may result in its release to the environment
through various waste streams.
□ Decomposition : When heated to decomposition it emits toxic
fumes of nitrogen oxides and Carbon oxides.
□ Occupational exposure to N-isopropylacrylamide may occur
through inhalation and dermal contact with this compound at
workplaces where N-isopropylacrylamide is produced or used
it can cause nerve damage.
6. □ Poly(N-isopropylacrylamide)
□ It can be synthesized from N-isopropylacrylamide . It is
synthesized via free-radical polymerization.
□ Homopolymerization
The process of free radical polymerization of a single type
of monomer, in this case, N-isopropylacrylamide, to form the
polymer is known as a homopolymerization. The radical
initiator azobisisobutyronitrile (AIBN) is commonly used in
radical polymerizations.
7. Poly(N-isopropyl acrylamide) is a temperature sensitive
hydrogel.
Poly(N-isopropyl acrylamide) has a lower critical solution
temperature (LCST) at 31–33°C in water. Below that
temperature, the hydrogel is swollen in water due to the hydrogen
bonding (hydrated state), and above that LCST, the hydrogel
collapsed (dehydrated) and becomes hydrophobic due to the
breakage of hydrogen bonding.
Importantly, the LCST of p(NIPAM) hydrogels can be
controlled by incorporating more hydrophilic or hydrophobic
monomer into the hydrogel structure.
8.
9. Application
□ The versatility of pNIPAM has led to finding uses in
macroscopic gels, microgels,membranes, sensors, biosensors,
thin films, tissue engineering, and drug delivery. (VPTT)
□ pNIPAM have also been used in pH-sensitive drug
delivery systems, antifouling coatings and “smart” optical
systems.
□ Some examples of these drug delivery systems may include the
intestinal delivery of human calcitonin, delivery of insulin and
the delivery of ibuprofen.
10. PNIPAM in Tissue Engineering (Tissue Regeneration)
https://www.researchgate.net/profile/Sajjad_Ashraf/
publication//-PNIPAM-scaffolds-and-growth-factors.png
13. Uses of N-isopropyl acrylamide
□ Binders in textiles, paper adhesives, detergents, cosmetic
□ One of the water-soluble monomers used in the production of
polyacrylamides, poly(acrylic acid), and poly(methacrylic
acid)
□ Chemical intermediate in the development of photosensitized
drug delivery systems
□ Core/shell precursor in gold nanoparticle applications
□ In the synthesis of thermosensitive hydrogels which are
hydrophilic polymer networks that are able to swell and retain
large amounts of water and maintain three-dimension swollen
structures.
14. □ Bulk-polymerized: hard shatterproof, transparent or colored
material (glass substitute, decorative illuminated signs, contact
lenses, dentures, medical instruments, specimen preservation,
furniture components).
□ Solution polymers: coatings for paper, textiles, etc.
□ Suspension-polymerized: beads and molding powders
(headlight lenses, adsorbents in chromatography, ion-exchange
resins).
□ Aqueous emulsions: adhesives, laminated structures, fabric
coatings, nonwoven fabrics.
15. 1 Water-in-oil Pickering emulsion
polymerization of N-isopropyl acrylamide
using starch-based nanoparticles as emulsifier.
Zhai, Kankan, et al.
(2019)
2 pH-Thermosensitive hydrogel based on
polyvinyl alcohol/sodium alginate/N-isopropyl
acrylamide composite for treating re-infected
wounds
A.S. Montaser et al.(2019)
3 Poly(N-isopropylacrylamide) and
Copolymers:A Review on Recent Progresses
in Biomedical Applications
Lanzalaco et al.
(2017)
S. No. Article Reference
16. 4 Development of Novel
N-isopropylacrylamide(NIPAAm)
Based Hydrogels with Varying Content
of Chrysin Multiacrylate
Shuo Tang, et,al
(2017)
5 Potential application of poly(N-
isopropylacrylamide) gel containing
polymeric micelles to drug delivery
systems
Yan, H., & Tsujii,
K. (2005)
6 Synthesis of N-isopropylacrylamide
from acrylonitrile and
isopropyl alcohol over solid acids
Chen, X., H.
Matsuda, and T.
Okuhara. (2000)
17. S.No Article Reference
7 Modulating the phase transition
temperature and thermosensitivity in
N-isopropylacrylamide copolymer gel
Ryo Yoshidai et. al
(1994)
8 Volume Phase Transitions of Ionized N-
Isopropylacrylamide gels
Shunsuke Hirotsu,et
al.(1987)
18. Reference
□ PubChemURL: https://pubchem.ncbi.nlm.nih.gov.
□ https://toxnet.nlm.nih.gov.
□ Gao, Y., Zago, G. P., Jia, Z., & Serpe, M. J. (2013). Controlled and triggered
small molecule release from a confined polymer film. ACS Applied Materials
& Interfaces, 5(19), 9803-9808
□ Hendrickson, G. R., & Lyon, L. A. (2009). Bioresponsive hydrogels for
sensing applications. Soft Matter, 5(1), 29-35.
□ Islam, M. R., & Serpe, M. J. (2014). Polymer-based devices for the label-free
detection of DNA in solution: low DNA concentrations yield large
signals. Analytical and Bioanalytical Chemistry, 406(19), 4777-4783.
□ Schild, H. G. (1992). Poly (N-isopropylacrylamide): experiment, theory and
application. Progress in Polymer Science, 17(2), 163-249.
□ Somasundaran, P. (Ed.). (2006). Encyclopedia of Surface and Colloid
Science (Vol. 2). CRC press.
19. □ Zhai, K., Pei, X., Wang, C., Deng, Y., Tan, Y., Bai, Y., ... & Wang, P.
(2019). Water-in-oil Pickering emulsion polymerization of N-isopropyl
acrylamide using starch-based nanoparticles as emulsifier. International
Journal of Biological Macromolecules.
□ Montaser, A. S., Rehan, M., & El-Naggar, M. E. (2019). pH-
Thermosensitive hydrogel based on polyvinyl alcohol/sodium alginate/N-
isopropyl acrylamide composite for treating re-infected
wounds. International Journal of Biological Macromolecules, 124, 1016-
1024.
□ Lanzalaco, S., & Armelin, E. (2017). Poly (n-isopropylacrylamide) and
copolymers: A review on Recent Progresses in Biomedical
Applications. Gels, 3(4), 36.
20. □ Tang, S., Floy, M., Bhandari, R., Dziubla, T., & Hilt, J. (2017).
Development of novel N-isopropylacrylamide (NIPAAm) based hydrogels
with varying content of chrysin multiacrylate. Gels, 3(4), 40.
□ Yan, H., & Tsujii, K. (2005). Potential application of poly (N-
isopropylacrylamide) gel containing polymeric micelles to drug delivery
systems. Colloids and Surfaces , Biointerfaces, 46(3), 142-146.
□ Chen, X., Matsuda, H., & Okuhara, T. (2000). Synthesis of N-
isopropylacrylamide from acrylonitrile and isopropyl alcohol over solid
acids. In Studies in Surface Science and Catalysis(Vol. 130, pp. 2657-
2662). Elsevier.
21. □ Yoshida, R., Sakai, K., Okano, T., & Sakurai, Y. (1995).
Modulating the phase transition temperature and
thermosensitivity in N-isopropylacrylamide copolymer
gels. Journal of Biomaterials Science, Polymer Edition, 6(6),
585-598.
□ Hirotsu, S., Hirokawa, Y., & Tanaka, T. (1987).
Volume‐phase transitions of ionized N‐isopropylacrylamide
gels. The Journal of Chemical Physics, 87(2), 1392-1395.