This document discusses recent genetic advances in cancer and HIV identification. It summarizes several research articles about identifying genes involved in these diseases. For cancer, researchers found a protein that pushes breast cancer cells to metastasize and identified a gene involved in cancer progression and metastasis. For HIV, studies identified genes that could help regulate the immune response to reduce side effects of treatment. These findings may help develop new targeted treatments and ways to diagnose, identify, and treat diseases linked to these genes.

1. GENETIC ADVANCES IN CANCER
AND HIV IDENTIFICATION
DANIELA GALLÓN ESTRADA
MOLECULAR BIOLOGY
LINA MARTÍNEZ
III SEMESTER
2014
PONTIFICIA BOLIVARIANA UNIVERSITY

4. INTRODUCTION
DNA and RNA have an important role in the
innovation of ways to treat some diseases
which involve alterations about cellular
function and the possibility to erase some bad
effects of classic treatments.

5. NEW 1
HUMAN CELLS' PROTEIN FACTORY HAS
AN ALTERNATE OPERATING MANUAL:
PROCESS MAY HELP BODY REIN IN
DISEASE-FIGHTING SIDE EFFECTS
July 9, 2014

6. NEW 1
The manifestation of genetic
polymorphisms in genes that are
implicated in immunity could change
some conditions which regulate the
status in HIV and the way to treat it.

7. NEW 1
Genic therapy is a technique that use genes to
treat or prevent diseases. The common ways
of this are the inclusion of a normal gene
changing an anormal gene although it could be
a reparation of an anormal gene or alteration of
activation and inactivation of a gene.
Antiretroviral therapy has like main objective
down the effects of HIV/AIDS doing that the
virus propagation get down and it does not
attack the immune system. However, some
drugs mechanisms used in this therapy could
attack another cells of the organism causing bad
effects.

8. NEW 1
New pathways to treat HIV offer to patients
the possibility to cut their infection rapidly.
Although it's just an investigation, its
conclusion is a part of a big puzzle which in
some time will give a better solution that
which exist now.

9. OBSERVATION
It is a breakthrough that can give us
many answers about treatment.
This research may have clearer
answers to some of the behaviors
generated by the body in different
pathologies as in the case of HIV
where immune response where gets
out of control and sometimes causing
death.

10. NEW 2
PROTEIN FOUND THAT PUSHES
BREAST CANCER CELLS TO
METASTASIZE
July 9, 2014

11. NEW 2
Recognize genes implicated in
progression of cancer is
important because it allows to do
a prognostic about the possible
evolution and address the
possible prevention of it.

12. NEW 2
A possible way about genetic
manipulation could be developed with
the conclusion of this study because it
describes a specific gene which is
involved in a several cancer
complication like a metastasize.

13. NEW 2
Development of new technologies which can help the treatment of some kind of
cancer is an important topic in the innovation of techniques because it could give to
patient the possibility to access to a specific and oriented treatment which could have
the capability to attack cancer origin and delete the alteration. All of that could be
made with genetic therapy and another drugs which could induce molecular and
cellular answers.

14. The recognition of the protein that
initiates all the pathological process of
cancer is a breakthrough because
with this data we can generate news
drugs to prevent the progression of
this disease.
OBSERVATION
Today cancer is a common disorder.
With this research have specific data on
which cancer is involved.

15. MEDICAL UTILITY
HIV treatment maybe is one of hardest
challenge for medicine because the only
way is the immunosuppression increasing
the risk of infections and bad defense when
an antigen get into the human body.

16. MEDICAL UTILITY
Identifying a gene that helps to
regulate the reduction of cellular
and humoral response but
preventing complete
immunosuppression also gives the
possibility of directing the
processing to a local target.

17. One more time the identification of a
gene implicated in cancer
development gives a light about new
ways to diagnosis, identification and
treatment of diseases which have this
gene so it allows get tools to attack a
determined kind of cancer.
MEDICAL UTILITY

18. Actually gene therapy has
increase its importance because
gives the possibility of induced
molecular changes in cells that
cause a better condition of the
patient so it's important recognize
the genes involved in each
disease.
MEDICAL UTILITY
Find genes which are important in diseases
like cancer and HIV represent advances in
the idea to develop treatments without
unfavorable secondary effects and more
effective drugs that attack the root of the
problem.

19. BIBLIOGRAPHY