This abstract reviews 8 studies on the use of antibiotics in treating children diagnosed with E. coli O157:H7 diarrhea and the risk of developing hemolytic uremic syndrome (HUS). While some studies had conflicting results, most larger studies found that antibiotic use increased the risk of HUS. Certain factors were associated with higher risk, such as severity of illness, starting antibiotics early in the diarrhea phase, and using bactericidal antibiotics. The conclusions indicate an increased risk was seen with larger sample sizes and certain antibiotics, timing of use, and illness severity may influence HUS risk.
Saccharomyces boulardii in the prevention of antibiotic-associated diarrhoea ...Utai Sukviwatsirikul
Saccharomyces boulardii in the prevention of antibiotic-associated
diarrhoea in children: a randomized double-blind placebo-controlled
trial
M. KOTOWSKA, P. ALBRECHT & H. SZAJEWSKA
Department of Pediatric Gastroenterology and Nutrition, The Medical University of Warsaw, Warsaw, Poland
Accepted for publication 24 November 2004
This collaboration between Albert Einstein College of Medicine and Cardozo Law builds upon the long history and rich clinical experience of the Montefiore-Einstein bioethics consultation service. With integrated courses designed specifically for the bioethics curriculum, our program provides personal enrichment while equipping you with the skills you need to navigate the nuances of policy and regulation in a changing healthcare environment.
Saccharomyces boulardii in the prevention of antibiotic-associated diarrhoea ...Utai Sukviwatsirikul
Saccharomyces boulardii in the prevention of antibiotic-associated
diarrhoea in children: a randomized double-blind placebo-controlled
trial
M. KOTOWSKA, P. ALBRECHT & H. SZAJEWSKA
Department of Pediatric Gastroenterology and Nutrition, The Medical University of Warsaw, Warsaw, Poland
Accepted for publication 24 November 2004
This collaboration between Albert Einstein College of Medicine and Cardozo Law builds upon the long history and rich clinical experience of the Montefiore-Einstein bioethics consultation service. With integrated courses designed specifically for the bioethics curriculum, our program provides personal enrichment while equipping you with the skills you need to navigate the nuances of policy and regulation in a changing healthcare environment.
Etiologia de la celulitis y Predicción clínica de la enfermedad Estreptocócic...Alex Castañeda-Sabogal
Etiologia de la celulitis. Estudio prospectivo y predicción clínica de la infeccion por Estreptococcus basado en la frecuencia encontrada de las especies de estreptococo
This collaboration between Albert Einstein College of Medicine and Cardozo Law builds upon the long history and rich clinical experience of the Montefiore-Einstein bioethics consultation service. With integrated courses designed specifically for the bioethics curriculum, our program provides personal enrichment while equipping you with the skills you need to navigate the nuances of policy and regulation in a changing healthcare environment.
Written composition reviewing the ethics of the distribution and utilization of antiviral medications for Ebola and HIV treatment in third-world countries.
Articulo que intenta demostrar en un modelo linear mixto de efectos al azar, que las variables edad, sexo y estado nutricional de un paciente coinfectado VIH/TB influyen en la recuperación del CD4
Molecular epidemiology is an emerging branch of epidemiology developed by merging molecular biology into epidemiological studies. Molecular epidemiology studies identify infectious diseases’ causation and pathogenesis and unravel infectious agents’ sources, reservoirs, circulation pattern, transmission pattern, transmission probability, and transmission order. Molecular epidemiology, an area of epidemiology that is somewhat ambiguous, encompasses utilization of biomarkers and genetics as tools to define both exposures (factors that are inherited) and outcomes (factors that are acquired). In last few decades, it has grown extensively to help to understand of disease ecology, in planning disease control, and in drafting health policies.
Epidemiology is the study and analysis of the patterns, causes, and effects of health, disease & production conditions in defined populations, in terms of space and temporality.
Acquia Content Hub: Connect Technologies & Extend Systems to Source ContentJake Borr
Today’s technology landscape is riddled with constantly evolving web platforms, exciting new technologies, and stubborn legacy systems. It’s easy for your business counterparts, who are rapidly creating content for these many sites and channels, to lose sight of what content is created and where it lives.
As a result, data and content are locked in back-end systems across your organization. And because it’s difficult and expensive to connect technologies, you and your team end up wasting time and resources in efforts to publish that content on the web.</p>
In our upcoming webinar, we’ll show you how Acquia Content Hub:
-Integrates with different technologies and legacy systems with our Rest API
-Normalizes content across systems through our CDF format
-Empowers Drupal developers to extend our Drupal modules for additional Drupal functionality
-Increases efficiencies, so your team can spend more time innovating, rather than searching and re-creating content
-Speeds your time to market with content rich sites
Etiologia de la celulitis y Predicción clínica de la enfermedad Estreptocócic...Alex Castañeda-Sabogal
Etiologia de la celulitis. Estudio prospectivo y predicción clínica de la infeccion por Estreptococcus basado en la frecuencia encontrada de las especies de estreptococo
This collaboration between Albert Einstein College of Medicine and Cardozo Law builds upon the long history and rich clinical experience of the Montefiore-Einstein bioethics consultation service. With integrated courses designed specifically for the bioethics curriculum, our program provides personal enrichment while equipping you with the skills you need to navigate the nuances of policy and regulation in a changing healthcare environment.
Written composition reviewing the ethics of the distribution and utilization of antiviral medications for Ebola and HIV treatment in third-world countries.
Articulo que intenta demostrar en un modelo linear mixto de efectos al azar, que las variables edad, sexo y estado nutricional de un paciente coinfectado VIH/TB influyen en la recuperación del CD4
Molecular epidemiology is an emerging branch of epidemiology developed by merging molecular biology into epidemiological studies. Molecular epidemiology studies identify infectious diseases’ causation and pathogenesis and unravel infectious agents’ sources, reservoirs, circulation pattern, transmission pattern, transmission probability, and transmission order. Molecular epidemiology, an area of epidemiology that is somewhat ambiguous, encompasses utilization of biomarkers and genetics as tools to define both exposures (factors that are inherited) and outcomes (factors that are acquired). In last few decades, it has grown extensively to help to understand of disease ecology, in planning disease control, and in drafting health policies.
Epidemiology is the study and analysis of the patterns, causes, and effects of health, disease & production conditions in defined populations, in terms of space and temporality.
Acquia Content Hub: Connect Technologies & Extend Systems to Source ContentJake Borr
Today’s technology landscape is riddled with constantly evolving web platforms, exciting new technologies, and stubborn legacy systems. It’s easy for your business counterparts, who are rapidly creating content for these many sites and channels, to lose sight of what content is created and where it lives.
As a result, data and content are locked in back-end systems across your organization. And because it’s difficult and expensive to connect technologies, you and your team end up wasting time and resources in efforts to publish that content on the web.</p>
In our upcoming webinar, we’ll show you how Acquia Content Hub:
-Integrates with different technologies and legacy systems with our Rest API
-Normalizes content across systems through our CDF format
-Empowers Drupal developers to extend our Drupal modules for additional Drupal functionality
-Increases efficiencies, so your team can spend more time innovating, rather than searching and re-creating content
-Speeds your time to market with content rich sites
Unifying Content + Data: Why Context is the Future of Digital ExperiencesJake Borr
Building a platform and strategy that will take your digital experiences into the next 5 years means stepping into uncharted territories. No one knows each device or channel that will be most popular in the future. With the pace of technology growth, predicting what you’ll need or what the preferred device will be, in even a few years, is incredibly difficult. While today you may think about mobile applications and websites, a few years from now augmented and virtual reality could be your largest growth potential.
By looking at the foundation of a well executed personalization program, we can set ourselves up for success and ensure we have the right tools. One of the main principles is that you will need to unify your sources of both content and of context, or user profile data. This unification will lead to smarter applications, better analytics and more possibilities to drive genuinely meaningful experiences for your customers.
Explore our future digital landscape with Digital strategist, Melanie Poitras and Dave Ingram and to learn about:
-Current and future use cases - ranging from in-store kiosks, to IoT and automobiles
-How systems of record for content and user profiles are converging to build a platform fit for the future
-What you need in place to build and optimize the digital experience of tomorrow
-5 things you should be doing today, regardless of your current personalization maturity
Dr. Theoklis Zaoutis - Antimicrobial Use and Stewardship in the Pediatric Out...John Blue
Antimicrobial Use and Stewardship in the Pediatric Outpatient Setting - Dr. Theoklis Zaoutis, Chief, Division of Infectious Diseases, Professor of Pediatrics and Epidemiology of the University of Pennsylvania, from the 2014 NIAA Symposium on Antibiotics Use and Resistance: Moving Forward Through Shared Stewardship, November 12-14, 2014, Atlanta, Georgia, USA.
More presentations at http://www.swinecast.com/2014-niaa-antibiotics-moving-forward-through-shared-stewardship
Prostate cancer is the most prevalent and second cause of death from cancer in
men worldwide. Immunotherapy is a new method for the treatment of several cancers
that fights cancer cells by strengthening the immune system through some medications.
While immunotherapy is a useful method for cancer treatment; its’ side effects still are
not totally clarified. Numbers of prostate cancer patients which take immunotherapy are
experiencing prostate inflammation and prostatitis after treatment period.
Enterococcus faecalis is Gram-positive and catalase-negative cocci that are common
in the intestines of humans and other animals and cause most enterococcal infections such as intestinal
infections, prostatitis, gastroenteritis and endocarditic. Present study aimed to evaluate the mRNA level of virulence genes which are involved in Enterococcus faecalis pathogenesis in prostate cancer patients that treated by immunotherapy. Expression level of gelatinase E (gelE) and Enterococcal surface protein (
esp genes were examined by Real time PCR in three groups of 68 male subjects. Group A normal subjects, group B prostate cancer patients before start treatment and group C prostate cancer patients after six months immunotherapy period.
Webinar: Defeating Superbugs: Hospitals on the Front Lines Modern Healthcare
About the Webinar: Defeating Superbugs: Hospitals on the Front Lines
http://www.modernhealthcare.com/article/20140917/INFO/309179926
Hospitals across the country are facing a grim reality in which some of the most deadly healthcare-associated infections they encounter are untreatable with first- or even second-line antibiotics. These “superbugs” affect at least 2 million Americans each year and lead to 23,000 deaths. And their threat is growing, public health officials warn. This editorial webinar and “Defeating Superbugs” white paper will explore the steps providers must take to ramp up surveillance efforts, promote appropriate antibiotic use and control outbreaks. Our panel of experts will share their organizations' experiences as well as proven strategies for success.
Registration for this webinar includes Modern Healthcare's “Defeating Superbugs” white paper, with proven tips and strategies for promoting appropriate antibiotic use, improving infection surveillance, identifying drug-resistant infections and dealing with outbreaks.
KEY TAKEAWAYS
- Best practices for effective antimicrobial stewardship
- Real-world examples of effective interventions, including universal rapid testing for drug-resistant MRSA
- Tips for engaging senior leadership
- Aggressive strategies for controlling outbreaks
PANELISTS
Lance Peterson
Director of the Clinical Microbiology and Infectious Disease Research Division
NorthShore University HealthSystem, Evanston, Ill.
Anurag Malani
Medical Director for the Infection Prevention and Antimicrobial Stewardship Programs
St. Joseph Mercy Hospital, Ann Arbor, Mich.
Robert Weinstein
Chief Medical Officer for Population Health
Chairman of the Department of Medicine, Cook County Health and Hospitals System; Professor, Rush University Medical Center, Chicago
MODERATOR
Maureen McKinney
Editorial Programs Manager
Modern Healthcare
A Study on Pattern of Using Prophylactic Antibiotics in Caesarean Sectioniosrphr_editor
The IOSR Journal of Pharmacy (IOSRPHR) is an open access online & offline peer reviewed international journal, which publishes innovative research papers, reviews, mini-reviews, short communications and notes dealing with Pharmaceutical Sciences( Pharmaceutical Technology, Pharmaceutics, Biopharmaceutics, Pharmacokinetics, Pharmaceutical/Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmacognosy & Phytochemistry, Pharmacology, Pharmaceutical Analysis, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics and Biotechnology of Pharmaceutical Interest........more details on Aim & Scope).
Running Head PICOT STATEMENT ON PRESSURE ULCERS1PICOT STA.docxgemaherd
Running Head: PICOT STATEMENT ON PRESSURE ULCERS
1
PICOT STATEMENT ON PRESSURE ULCERS
2
PICOT Question pressure ulcers
Student’s Name: Vladimir Andino
University Affiliation: GCU
PICOT Question
According to a report by CDC, approximately 3 million people develop pressure injuries each year. Pressure ulcers reduce the quality of quality of life. Each year a considerably large number of people are diagnosed with pressure injuries. Various ways can be used to prevent the progression of this phenomenon. This paper evaluates the most effective option that can be applied to prevent pressure injuries. It is framed based on the PICOT statement,
(P) patients with severe pressure injuries.
(I) is the surgical removal of ulcers.
(C) compared with the administration of antibiotics.
(O) more effective in treatment of pressure injuries.
(T) in the short-term medical plan.
Edlich, R., Winters, K. L., Woodard, C. R., Buschbacher, R. M., Long III, W. B., Gebhart, J. H., & Ma, E. K. (2004). Pressure ulcer prevention. Journal of long-term effects of medical implants, 14(4).
This study explicitly analyzes prevention as well as treatment actions that should be taken by nurses who carry the burden of reducing this phenomenon. The study is a qualitative study, in the sense that it does not involve an analysis of data both mathematically and graphically.
The authors use published information to support their arguments hence it is a peer-reviewed secondary study.
After evaluation, the study confirms that nurses should conduct preventative measures to reduce the effects of pressure injuries. This can be achieved by involving various types of treatment and nursing interventions to mention a few.
Bluestein, D., & Javaheri, A. (2008). Pressure ulcers: prevention, evaluation, and management. American family physician, 78(10).
. This study comprehensively evaluates the predominant factors associated with wounds. The study relies on pre-existing data.
The authors conclude that appropriate dressing is important to prevent critical health issues. It is from this point of view that the study advises on thorough check-ups and in case there are no improvement medicals procedures should be taken.
Vanderwee, K., Defloor, T., Beeckman, D., Demarré, L., Verhaeghe, S., Van Durme, T., & Gobert, M. (2011). Assessing the adequacy of pressure ulcer prevention in hospitals: a nationwide prevalence survey. BMJ Quality & Safety, 20(3), 260-267.
The study assesses the efficacy of pressure ulcer prevention in health cares. This is a primary study because the author organizes, collect and analyzes data. Also, this is a quantitative study because it statistically analyzes data.
The study confirmed that there is a limited use of proper preventions measures with respect to pressure injuries and wounds. In other words, the study confirmed that there is a rather low-quality care.
Sving, E., Gunningberg, L., Högman, M., & Mamhidir, A. G. (2012). Registered nurses’ attention t ...
RESEARCH ARTICLE Open AccessThe impact of repeated vaccina.docxrgladys1
RESEARCH ARTICLE Open Access
The impact of repeated vaccination on
influenza vaccine effectiveness: a
systematic review and meta-analysis
Lauren C. Ramsay1, Sarah A. Buchan2, Robert G. Stirling2,3, Benjamin J. Cowling4, Shuo Feng4,
Jeffrey C. Kwong1,2,5,6,7 and Bryna F. Warshawsky1,8*
Abstract
Background: Conflicting results regarding the impact of repeated vaccination on influenza vaccine effectiveness
(VE) may cause confusion regarding the benefits of receiving the current season’s vaccine.
Methods: We systematically searched MEDLINE, Embase, PubMed, and Cumulative Index to Nursing and Allied Health
Literature from database inception to August 17, 2016, for observational studies published in English that reported VE
against laboratory-confirmed influenza for four vaccination groups, namely current season only, prior season only, both
seasons, and neither season. We pooled differences in VE (ΔVE) between vaccination groups by influenza season and
type/subtype using a random effects model. The study protocol is registered with PROSPERO (registration number:
CRD42016037241).
Results: We identified 3435 unique articles, reviewed the full text of 634, and included 20 for meta-analysis. Compared to
prior season vaccination only, vaccination in both seasons was associated with greater protection against influenza H1N1
(ΔVE = 26%; 95% CI, 15% to 36%) and B (ΔVE = 24%; 95% CI, 7% to 42%), but not H3N2 (ΔVE = 10%; 95% CI, –6% to 25%).
Compared to no vaccination for either season, individuals who received the current season’s vaccine had greater
protection against H1N1 (ΔVE = 61%; 95% CI, 50% to 70%), H3N2 (ΔVE = 41%; 95% CI, 33% to 48%), and B (ΔVE = 62%;
95% CI, 54% to 68%). We observed no differences in VE between vaccination in both seasons and the current season only
for H1N1 (ΔVE = 4%; 95% CI, –7% to 15%), H3N2 (ΔVE = –12%; 95% CI, –27% to 4%), or B (ΔVE = –8%; 95% CI, –17% to 1%).
Conclusions: From the patient perspective, our results support current season vaccination regardless of prior season
vaccination. We found no overall evidence that prior season vaccination negatively impacts current season VE. It is
important that future VE studies include vaccination history over multiple seasons in order to evaluate repeated
vaccination in more detail.
Keywords: Influenza, Vaccine effectiveness, Repeated vaccination
Background
Seasonal influenza vaccination is the predominant strat-
egy for preventing influenza-related morbidity and mor-
tality. Annual vaccination is recommended because of
waning immunity and because influenza strains undergo
antigenic drift, necessitating reviewing and, in most sea-
sons, changing of the vaccine to better match the up-
coming season’s strains [1]. Because of the frequently
changing vaccine, influenza vaccine effectiveness (VE) is
assessed annually.
With increasing numbers of people being immunized
against influenza annually, the impact of repeated vac-
cination has gained significant interest. Of particul.
RESEARCH ARTICLE Open AccessThe impact of repeated vaccina.docx
Neha abstract submission-2
1. CONTROL ID: 2378979
CONTACT (NAME ONLY): Neha More
PRESENTATION TYPE: Abstract
CURRENT CATEGORY: Infectious Diseases
Abstract
TITLE: USE OF ANTIBIOTICS IN TREATMENT OF CHILDREN DIAGNOSED WITH ESCHERICHIA COLI 0157:H7
DIARRHEA AND RISK OF DEVELOPING HEMOLYTIC UREMIC SYNDROME (HUS): REVIEW OF THE
LITERATURE
AUTHORS (FIRST NAME INITIAL LAST NAME): N. N. More
1
, N. Cheranda
1
, J. Rozenblit
1
, J. Kim
1
, Y. Kim
1
, N.
Baskaran
1
, M. Vyakaranam
1
, B. Afghani
1, 2
INSTITUTIONS (ALL):
1. University of California, Irvine Medical School, Irvine, CA, United States.
2. CHOC Hospital, Orange, CA, United States.
ABSTRACT BODY:
Purpose of Study: The use of antibiotics in diarrhea caused by Escherichia Coli (E. Coli) 0157:H7 in the pediatric
population remains contentious. The purpose of this review was to determine whether antibiotics increase the risk of
HUS.
Methods Used: PubMed and Google Scholar search engines were used to find studies that included children under
the age of 21 and diagnosed with HUS caused by E. Coli O157:H7.
Summary of Results: Eight studies regarding the use of antibiotics in children with possible signs of HUS satisfied our
inclusion criteria (see tables below for prospective and retrospective studies). Although there were conflicting results,
majority of studies with larger sample size showed giving antibiotics increased the risk of HUS. Severity of disease,
starting antibiotics early during diarrheal phase and bactericidal antibiotics were associated with increased risk of
HUS.
Conclusions: Studies which included larger sample size have shown an increased risk of HUS after use of antibiotics.
Severity of illness, the type of antibiotic and duration of symptoms before start of antibiotics may influence the risk of
developing HUS.
Table 1: Prospective Studies
Author
and Year
Age of
Patients
(yrs)
Total Antibiotic
s used
Those
got
antibiotic
s &
develope
d HUS
Those
without
antibiotic
s &
develope
d HUS
Effect of
Antibiotic
s
(Success
, Harm)
P values
Wong
CS, 2000
<18 71 Variety of
Antibiotic
s
5/9
(56%)
5/62
(8%)
Harm p<0.001
Wong
CS, 2012
<18 259 ampicillin
,
azithrom
ycin,cefot
axime,
and
trimethop
9/25
(36%)
27/234
(12%)
Harm p=0.001
2. rim-
sulfamet
hoxazole
Geerdes-
Fenge
HF, 2013
<18 24 Ciproflox
acin
Cefotaxi
me,
amoxicilli
n,
metronid
azole
4/7
(57%)
15/17
(88%)
No Effect p=0.12
Proulx,
1992
<21 77 Cotrimox
azole
2/22
(9%)
4/25
(16%)
No Effect p=0.67
Table 2: Retrospective Studies
Author
and Year
Age of
Patients
(yrs)
Total Antibiotic
Name
Patients
treated
with
antibiotic
s &
develope
d HUS
Patient
treated
without
antibiotic
s &
develope
d HUS
Effect of
Antibiotic
s
(Success
, Harm
P values
Ostroff,
1989
<10
Subgrou
p
75 Erythrom
ycin,
ampicillin
, and
cotrimox
azole
3/8
(38%)
5/12
(22%)
No to
minor
Effect
p=0.07
Beth P.
Bell,
1997
<15 278 TMP/SM
Z,
Ampicillin
or
Amoxicilli
n,
Cephalos
porin,
Metronid
azole
8/50
(16%)
28/128
(22%)
No Effect p=0.56
Pavia,
1990
<20 23 Cotrimox
azole,
5/8
(72%)
0/7
(28%)
Harm p<0.05
3. sulfonam
ide
Smith
KE, 2012
<20 188 Bacterici
dal
antibiotic
s
12/63
(19%)
6/125
(5%)
Harm p<0.01
(No Image Selected)
AWARDS: WAFMR/WSPR Outstanding Student Research Awards