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Mini-Gastric Bypass
Excellent Rx GERD
Dr. Rutledge
(702) 483-7133
Email DrR@clos.net
https://mgbguidelines.wordpress.com/gastric-pouch-creation/
•Mini-Gastric Bypass
• Anyone can do a “single
anastomosis gastric bypass”
• That Does Not mean they
can/are doing the true
“Mini-Gastric Bypass” (MGB)
• See the Following Example...
GERD
•Rx with Nissen
•Results of Nissen
•GERD in Bariatric Surgery
•Band Sleeve CAUSE GERD
•RNY Rx GERD
•MGB Best Rx GERD
Understanding Why?
Systematic review: Laparoscopic fundoplication for
gastroesophageal reflux disease
Laparoscopic fundoplication (LF) for
gastroesophageal reflux disease (GERD).
10 years after LF, 36% reported heartburn &
29% reported regurgitation.
The proportion using PPIs increased, from
9% in year 1 to 18% at 10 years.
A randomized controlled trial of
laparoscopic Nissen fundoplication
versus proton pump inhibitors for the
treatment of patients with chronic
gastroesophageal reflux disease
(GERD): 3-year outcomes.
•Surg Endosc. 2011
Aug;25(8):2547-54.
RCT; Nissen vs PPIs
•A randomized controlled trial (RCT)
investigated patients with
gastroesophageal reflux disease
(GERD) who were stable and
symptomatically controlled with long-
term medical therapy to compare
ongoing optimized medical therapy
with laparoscopic Nissen
fundoplication (LNF).
Nissen vs PPIs: No difference
•GERD Sx or
Acid exposure on 24-h pH
monitoring
•There were six treatment failures
(12%) in the surgical group and
eight treatment failures (16%) in
the medical group by 3 years.
RCT: CONCLUSIONS:
For patients whose GERD
symptoms are stable and
controlled with PPI,
continuing medical therapy
and laparoscopic anti-reflux
surgery are equally effective
Use of proton pump
inhibitors after anti-reflux
surgery: a nationwide
register-based follow-up
study
•Jan 28, 2014 -
•Lødrup A(1), Pottegård
A(2), Hallas J(2),
Denmark Nationwide health
care registry study
•PPI use after Anti-reflux surgery
(ARS) in the general Danish
population using nationwide health
care registries.
•A nationwide retrospective follow-
up study of all patients aged ≥18
and undergoing first-time ARS in
Denmark during 1996–2010
Denmark Nationwide health
care registry study
• Female gender, high age,
recent ARS, previous use of
PPI & use of NSAIDs drugs or
antiplatelet therapy
significantly increased the risk
of PPI use (Nissen failure).
Long term failure of Nissen
•3465 patients ARS
•5, 10 & 15-year risks of
New PPI Rx =
57%, 72% & *83%*, respectively
•5, 10 & 15-year risks
Long-term PPI use =
30%, 41% and *57%*
Nissen Failure
• Conclusions Risk of PPI use after
ARS high!
• More than 50% of patients became
long-term PPI users
• Patients should be made aware
that long-term PPI therapy is often
necessary after Nissen.
Majority of Gastro-
Oesophageal Reflux Disease
Patients Continue to Use
Proton Pump Inhibitors After
Anti-reflux Surgery (Nissen)
A Madan et al. Aliment Pharmacol Ther
2006 Mar 01
Nissen Failure 80% Rx PPIs
•Nissen fundoplication at our
institution over a period of over
3 years were asked to complete
a questionnaire
•80% patients were still taking
anti-reflux medications
including proton pump
inhibitors
Rx GERD with Nissen
Very Questionable Results
MGB Rx GERD
Survey 3,000 MGB Patients
• 64% of MGB patients taking
antacid medications for GERD
preop (PPIs, H2Blockers or
Antacids)
• Post MGB resolution of GERD
Sx with discontinuation of
medications 81%
MGB Rx GERD
Equal to or Better Than
Nissen
• How Does it Work?
MGB Rx GERD
Mechanism of Action
1. Reduction of Acid
Production
2. Weight loss
3. Downward traction on the
stomach
4. *Creation of LOW Pressure
System*
MGB Rx GERD
Mechanism of Action
1. Reduction of Acid
Production
2. Weight loss
3. Downward traction on the
stomach
4. *Creation of LOW Pressure
System*
Conclusions
• GERD common serious problem
in Bariatric patients
• Nissen “gold standard” poor
results + = simply taking PPI's
• Dr Rutledge MGB Series:
80% success Rx GERD
• Understand WHY!
• MGB Good to Excellent Rx GERD

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Mini-Gastric Bypass Excellent Rx GERD

  • 2. https://mgbguidelines.wordpress.com/gastric-pouch-creation/ •Mini-Gastric Bypass • Anyone can do a “single anastomosis gastric bypass” • That Does Not mean they can/are doing the true “Mini-Gastric Bypass” (MGB) • See the Following Example...
  • 3. GERD •Rx with Nissen •Results of Nissen •GERD in Bariatric Surgery •Band Sleeve CAUSE GERD •RNY Rx GERD •MGB Best Rx GERD Understanding Why?
  • 4. Systematic review: Laparoscopic fundoplication for gastroesophageal reflux disease Laparoscopic fundoplication (LF) for gastroesophageal reflux disease (GERD). 10 years after LF, 36% reported heartburn & 29% reported regurgitation. The proportion using PPIs increased, from 9% in year 1 to 18% at 10 years.
  • 5. A randomized controlled trial of laparoscopic Nissen fundoplication versus proton pump inhibitors for the treatment of patients with chronic gastroesophageal reflux disease (GERD): 3-year outcomes. •Surg Endosc. 2011 Aug;25(8):2547-54.
  • 6. RCT; Nissen vs PPIs •A randomized controlled trial (RCT) investigated patients with gastroesophageal reflux disease (GERD) who were stable and symptomatically controlled with long- term medical therapy to compare ongoing optimized medical therapy with laparoscopic Nissen fundoplication (LNF).
  • 7. Nissen vs PPIs: No difference •GERD Sx or Acid exposure on 24-h pH monitoring •There were six treatment failures (12%) in the surgical group and eight treatment failures (16%) in the medical group by 3 years.
  • 8. RCT: CONCLUSIONS: For patients whose GERD symptoms are stable and controlled with PPI, continuing medical therapy and laparoscopic anti-reflux surgery are equally effective
  • 9. Use of proton pump inhibitors after anti-reflux surgery: a nationwide register-based follow-up study •Jan 28, 2014 - •Lødrup A(1), Pottegård A(2), Hallas J(2),
  • 10. Denmark Nationwide health care registry study •PPI use after Anti-reflux surgery (ARS) in the general Danish population using nationwide health care registries. •A nationwide retrospective follow- up study of all patients aged ≥18 and undergoing first-time ARS in Denmark during 1996–2010
  • 11. Denmark Nationwide health care registry study • Female gender, high age, recent ARS, previous use of PPI & use of NSAIDs drugs or antiplatelet therapy significantly increased the risk of PPI use (Nissen failure).
  • 12. Long term failure of Nissen •3465 patients ARS •5, 10 & 15-year risks of New PPI Rx = 57%, 72% & *83%*, respectively •5, 10 & 15-year risks Long-term PPI use = 30%, 41% and *57%*
  • 13. Nissen Failure • Conclusions Risk of PPI use after ARS high! • More than 50% of patients became long-term PPI users • Patients should be made aware that long-term PPI therapy is often necessary after Nissen.
  • 14. Majority of Gastro- Oesophageal Reflux Disease Patients Continue to Use Proton Pump Inhibitors After Anti-reflux Surgery (Nissen) A Madan et al. Aliment Pharmacol Ther 2006 Mar 01
  • 15. Nissen Failure 80% Rx PPIs •Nissen fundoplication at our institution over a period of over 3 years were asked to complete a questionnaire •80% patients were still taking anti-reflux medications including proton pump inhibitors
  • 16. Rx GERD with Nissen Very Questionable Results
  • 18. Survey 3,000 MGB Patients • 64% of MGB patients taking antacid medications for GERD preop (PPIs, H2Blockers or Antacids) • Post MGB resolution of GERD Sx with discontinuation of medications 81%
  • 19. MGB Rx GERD Equal to or Better Than Nissen • How Does it Work?
  • 20. MGB Rx GERD Mechanism of Action 1. Reduction of Acid Production 2. Weight loss 3. Downward traction on the stomach 4. *Creation of LOW Pressure System*
  • 21. MGB Rx GERD Mechanism of Action 1. Reduction of Acid Production 2. Weight loss 3. Downward traction on the stomach 4. *Creation of LOW Pressure System*
  • 22. Conclusions • GERD common serious problem in Bariatric patients • Nissen “gold standard” poor results + = simply taking PPI's • Dr Rutledge MGB Series: 80% success Rx GERD • Understand WHY! • MGB Good to Excellent Rx GERD