Xenobots are the world's first living, self-healing robots created by scientists at the University of Vermont and Tufts University. They are millimeter-sized robots constructed from stem cells of the African clawed frog and can walk, swim, and survive for weeks without food. To create the Xenobots, living stem cells were scraped from frog embryos, cut and reshaped using microtools under a microscope into specific body forms designed by a supercomputer. The cells then self-organized to form the designed structures and their pulsing heart muscle cells allow them to move. Potential applications of these biodegradable Xenobots include searching out hazardous compounds, gathering microplastics in oceans, and traveling inside arteries

1. PRESENTED BY- VARSHA R. WADNERE.
SECOND YEAR PHARM D.
ROLL NO- PD229.
XENOBOT -WORLD FIRST
LIVING,SELF HEALING ROBOTS.

2.  The research was done by University of Vermont and Tufts
University’s Allen
Discovery center and research was published on January 13 2020.
 World’s first living,self healing robots using stem cells from frogs.
 Xenobots are named from African clawed frog (Xenopus laevis) from
which stem cells are taken.
 The machine are less than a millimeter(0.04 inches)wide,650-750 microns
in diameter smaller than pinhead-small enough to travel inside human
bodies.
 They can walk and swim,survive for weeks without food.
 Stem cells are unspecialized cells that have the ability to develop into
different cell types.

3.  How they are made-
 The living stem cells are scraped from frog embryo seperated into single
cells and left them to incubate.
 Then the cells were cut and reshaped into specific “body forms”using
tiny forceps(tiny than electrode) and joined under microscope and
design as specified by a supercomputer.
 Then cells then began to work and form their structure.
 Their pulsing heart muscle cells allowed the robot to move on its own.
 We wanted xenobot to work as we want and adaptable to humans so its
structure and it’s movement are made by supercomputer Algorithms.
 Xenobot are small step towards cracking “morphogenetic code” and it
provides way to organize, store information based on history and
environment.

4. The anatomical blueprint
for a computer designed
organism discovered on a
UVM supercomputer
The living organism,built
entirely from frog skin(green)
and heart muscle(red) cells.

5. APPLICATIONS-
1.Searching out nasty compounds or radioactive
contamination.
2.Gathering microplastic in the oceans.
3.Traveling in arteries to scrape out plaque.
4.There are many side effects of plastic, metals,etc in
environment there are many ways to eliminate them but
eventually they are also found to be harmful to humans but
Xenobots are fully biodegradable i.e when they are done
with their job after seven days,they are just dead skin cells.
5.Transport drugs wherever it is needed in a body.
6.They have self healing properties so it can be used in tissue
damage condition.
7.They can repair birth defects,reprogram tumors into
normal tissue,regenerate after traumatic injury or
degenerative disease,and defeat ageing.

6. THANK YOU.