Rafi Nave, VP R&D, Given Imaging, presents at mHealth Israel Conference & Business Contest, October 7, 2013. Title is Given Imaging- Capsule Communication Challenges
Technology Experience within Healthcare: The Evolution of HUXMark A.M. Kramer
OVERVIEW: This keynote presentation is a quick (non-detailed view) describing and sharing evidence on how technology is evolving and influencing the healthcare experience. Emphasis will be placed on the “Technology Experience” of patients and healthcare providers (medical doctors, nurses, technicians) Furthermore, this keynote will share personal observations of how technology experience within medicine and healthcare is evolving from a patient perspective.
VIDEO PLAYLIST: http://bit.ly/huxvideos
Technology Experience within Healthcare: The Evolution of HUXMark A.M. Kramer
OVERVIEW: This keynote presentation is a quick (non-detailed view) describing and sharing evidence on how technology is evolving and influencing the healthcare experience. Emphasis will be placed on the “Technology Experience” of patients and healthcare providers (medical doctors, nurses, technicians) Furthermore, this keynote will share personal observations of how technology experience within medicine and healthcare is evolving from a patient perspective.
VIDEO PLAYLIST: http://bit.ly/huxvideos
“Alopecia-less” Whole Brain Radiotherapy: Preliminary Experience and OutcomesTodd Scarbrough
Whole brain radiotherapy (WBRT) is indicated for many patients with brain metastases. Most of these patients develop alopecia with standard WBRT technique (opposed lateral fields). A multi-field, very conformal beam arrangement might limit scalp dose thereby resulting in less or eliminated alopecia toxicity. We present our initial clinical experience with a new technique of WBRT, as well as limited comparative analyses of dosimetric data.
Self-charging, Highly Accurate Insole-Based Health Trackers for Medical Grade...INVIZA® HEALTH
INVIZA® HEALTH generates power from piezoelectric, mechanical energy harvesting to enable its health and fitness sensor suite. In addition, by using multiple sensor's output data via software, i.e. "sensor fusion" INVIZA has learned to lower power overall sensor and electronics power consumption while simultaneously increasing health and fitness measured parameter's accuracy. This leads to the insole tracker's battery staying 100% full while the user obtains the most accurate data.
MOBILE PHONE & MOBILE TOWER RADIATION HAZARDS Neha Kumar
Presentation by Prof. Girish Kumar -
Council for Fair Business Practices (CFBP) organized a talk on "MOBILE PHONE & TOWER RADIATION" on Friday 24th June, 2011 at 06.00 p.m at the Hall of Indian Merchants Chamber, Churchgate, Mumbai 400 020.
Good developments seem to be taking place post WHO excepts health problems. First time a person from the industry (Former Regional Director, West and South Operations, Indus Towers Ltd.) excepted that radiation from mobile towers lead to health problems at the event.
People were keen to look for solutions for the problem.
Michigan HealthTech Market Map 2024. Includes 7 categories: Policy Makers, Academic Innovation Centers, Digital Health Providers, Healthcare Providers, Payers / Insurance, Device Companies, Life Science Companies, Innovation Accelerators. Developed by the Michigan-Israel Business Accelerator
June 3, 2024 Anti-Semitism Letter Sent to MIT President Kornbluth and MIT Cor...Levi Shapiro
Letter from the Congress of the United States regarding Anti-Semitism sent June 3rd to MIT President Sally Kornbluth, MIT Corp Chair, Mark Gorenberg
Dear Dr. Kornbluth and Mr. Gorenberg,
The US House of Representatives is deeply concerned by ongoing and pervasive acts of antisemitic
harassment and intimidation at the Massachusetts Institute of Technology (MIT). Failing to act decisively to ensure a safe learning environment for all students would be a grave dereliction of your responsibilities as President of MIT and Chair of the MIT Corporation.
This Congress will not stand idly by and allow an environment hostile to Jewish students to persist. The House believes that your institution is in violation of Title VI of the Civil Rights Act, and the inability or
unwillingness to rectify this violation through action requires accountability.
Postsecondary education is a unique opportunity for students to learn and have their ideas and beliefs challenged. However, universities receiving hundreds of millions of federal funds annually have denied
students that opportunity and have been hijacked to become venues for the promotion of terrorism, antisemitic harassment and intimidation, unlawful encampments, and in some cases, assaults and riots.
The House of Representatives will not countenance the use of federal funds to indoctrinate students into hateful, antisemitic, anti-American supporters of terrorism. Investigations into campus antisemitism by the Committee on Education and the Workforce and the Committee on Ways and Means have been expanded into a Congress-wide probe across all relevant jurisdictions to address this national crisis. The undersigned Committees will conduct oversight into the use of federal funds at MIT and its learning environment under authorities granted to each Committee.
• The Committee on Education and the Workforce has been investigating your institution since December 7, 2023. The Committee has broad jurisdiction over postsecondary education, including its compliance with Title VI of the Civil Rights Act, campus safety concerns over disruptions to the learning environment, and the awarding of federal student aid under the Higher Education Act.
• The Committee on Oversight and Accountability is investigating the sources of funding and other support flowing to groups espousing pro-Hamas propaganda and engaged in antisemitic harassment and intimidation of students. The Committee on Oversight and Accountability is the principal oversight committee of the US House of Representatives and has broad authority to investigate “any matter” at “any time” under House Rule X.
• The Committee on Ways and Means has been investigating several universities since November 15, 2023, when the Committee held a hearing entitled From Ivory Towers to Dark Corners: Investigating the Nexus Between Antisemitism, Tax-Exempt Universities, and Terror Financing. The Committee followed the hearing with letters to those institutions on January 10, 202
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Whole brain radiotherapy (WBRT) is indicated for many patients with brain metastases. Most of these patients develop alopecia with standard WBRT technique (opposed lateral fields). A multi-field, very conformal beam arrangement might limit scalp dose thereby resulting in less or eliminated alopecia toxicity. We present our initial clinical experience with a new technique of WBRT, as well as limited comparative analyses of dosimetric data.
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Presentation by Prof. Girish Kumar -
Council for Fair Business Practices (CFBP) organized a talk on "MOBILE PHONE & TOWER RADIATION" on Friday 24th June, 2011 at 06.00 p.m at the Hall of Indian Merchants Chamber, Churchgate, Mumbai 400 020.
Good developments seem to be taking place post WHO excepts health problems. First time a person from the industry (Former Regional Director, West and South Operations, Indus Towers Ltd.) excepted that radiation from mobile towers lead to health problems at the event.
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June 3, 2024 Anti-Semitism Letter Sent to MIT President Kornbluth and MIT Cor...Levi Shapiro
Letter from the Congress of the United States regarding Anti-Semitism sent June 3rd to MIT President Sally Kornbluth, MIT Corp Chair, Mark Gorenberg
Dear Dr. Kornbluth and Mr. Gorenberg,
The US House of Representatives is deeply concerned by ongoing and pervasive acts of antisemitic
harassment and intimidation at the Massachusetts Institute of Technology (MIT). Failing to act decisively to ensure a safe learning environment for all students would be a grave dereliction of your responsibilities as President of MIT and Chair of the MIT Corporation.
This Congress will not stand idly by and allow an environment hostile to Jewish students to persist. The House believes that your institution is in violation of Title VI of the Civil Rights Act, and the inability or
unwillingness to rectify this violation through action requires accountability.
Postsecondary education is a unique opportunity for students to learn and have their ideas and beliefs challenged. However, universities receiving hundreds of millions of federal funds annually have denied
students that opportunity and have been hijacked to become venues for the promotion of terrorism, antisemitic harassment and intimidation, unlawful encampments, and in some cases, assaults and riots.
The House of Representatives will not countenance the use of federal funds to indoctrinate students into hateful, antisemitic, anti-American supporters of terrorism. Investigations into campus antisemitism by the Committee on Education and the Workforce and the Committee on Ways and Means have been expanded into a Congress-wide probe across all relevant jurisdictions to address this national crisis. The undersigned Committees will conduct oversight into the use of federal funds at MIT and its learning environment under authorities granted to each Committee.
• The Committee on Education and the Workforce has been investigating your institution since December 7, 2023. The Committee has broad jurisdiction over postsecondary education, including its compliance with Title VI of the Civil Rights Act, campus safety concerns over disruptions to the learning environment, and the awarding of federal student aid under the Higher Education Act.
• The Committee on Oversight and Accountability is investigating the sources of funding and other support flowing to groups espousing pro-Hamas propaganda and engaged in antisemitic harassment and intimidation of students. The Committee on Oversight and Accountability is the principal oversight committee of the US House of Representatives and has broad authority to investigate “any matter” at “any time” under House Rule X.
• The Committee on Ways and Means has been investigating several universities since November 15, 2023, when the Committee held a hearing entitled From Ivory Towers to Dark Corners: Investigating the Nexus Between Antisemitism, Tax-Exempt Universities, and Terror Financing. The Committee followed the hearing with letters to those institutions on January 10, 202
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June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
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- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
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- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
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Healthcare Market Overview, May 2024: Funding, Financing and M&A, from Oppenh...Levi Shapiro
Oppenheimer & Co. Inc, co-Head of Healthcare Investment Banking, Michael Margolis, provides H1 Healthcare Financing, Funding and M&A Overview. Table of Contents
1. Broader Market Overview
2. Biotech M&A Market Overview
3. Private Biotech Financing Market Update
4. Key Advice For Healthcare Companies
Current State of Play; Healthcare has Underperformed the Broader Market Over the Last Twelve Months; Signal-to-Noise is Getting Worse; Healthcare IPO Activity has Decreased Significantly Since 20–21 Pandemic Levels; Biotech Financing Activity Has Remained Robust in 2024; Biotech M&A Market Remains Incredibly Active; Biotech M&A Market Remains Incredibly Active; Big Pharma Upcoming Patent Expirations; Since November 2023 Oncology has accounted for over half of all M&A; Oncology, Autoimmune / I&I, and CV & Metabolic Remain the Top Areas in M&A; Small Molecule Beats Out All Other Modalities in M&A Despite IRA Concerns; Value of Big Pharma Acquisitions by Therapeutic Area in Q1 2024; Private Financing Market Update; 2024 Private Placement Activity On Track to Approach, If Not Exceed, 2020 Levels; Oncology, Particularly Solid Tumor, Continues to Attract VC Investors; Despite the IRA, Small Molecules Continue to Attract VC Dollars; Preclinical-Stage Companies Make Up Almost Half of Private Placements in 2023; Valuations by Development Stage – 2023; Typical Biotech Investors Remained Active in Q1 2024; 23 $100M+ Deals were Raised in Q1 2024; Biotech Fundraising Momentum Continued into 2024; Key Advice For Israeli Healthcare Companies; Although Israel has Strong Presence on US Public Markets, There is Room to Grow; Telling Your Story Effectively; Interacting with Investors to Build Long-term Credibility; Seven Simple Rules for Pitch Decks;
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Description of the Version Bravo intensive entrepreneurial launch program for 7 Israeli and 7 US former Navy SEALs. Details about each startup concept, the CEOs, the sector, etc.
Radical Life Extension_Dr. Leon Peshkin_Dec 2023Levi Shapiro
Presentation for mHealth Israel by Dr. Leon Peshkin, Harvard Medical School, exploring research into Embryology and Longevity, emphasizing Germline and protein aggregates. Includes current overview, anti aging through history, Lifespan Expansion, ALEC: Animal Life Expectancy in Controls, Scalable Platform in Pharmacobiology, Embryos Cleanse Protein Aggregates, Lysosomal switch triggers proteostasis renewal, Xenopus, Rejuvenation Roadmap, Citizen Science Approach to Aging, Xenopus: Maternal Dowry Molecules, Human Disease Modeling
Israel’s Life Science Hub 2023 English Abstract.pdfLevi Shapiro
The war between Israel and Hamas brings its own set of business
challenges. Challenges that may impact how we communicate with
partners and investors abroad. We should portray the life science sector as resilient and adaptable, even in times of crisis. This document is a a messaging outline for Israel's Life Science Hub despite the war with Hamas. Four key points to emphasize:
1) Global activity (resilience and agility)
2) Continuity of care and preventive medicine
3) World leading clinical trials industry
4) Dynamic scientific, research and entrepreneurial ecosystems
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We, 465 MIT Alumni, Staff, and Students, are writing to express our deep concern, fear, and disappointment regarding the recent protest that took place Thursday afternoon, in front of the MIT Stratton Student Center. While we fully support the principles of free
speech and the right to peaceful assembly, it is essential that we also prioritize the safety and well-being of all members of the MIT
community.
During the protest, a particular slogan was prominently displayed and chanted, which has raised significant concerns. The slogan
"From the [Jordan] river to the [Mediterranean] sea, Palestine will be free!" has been a source of contention due to its potential
implications and the real safety risks it poses to Jewish and Israeli students on campus [See video footage attached]. This slogan
has been time and again associated with calls for the destruction of the State of Israel and has been used in contexts that
promote violence, which raises legitimate concerns about the safety and security of our Jewish and Israeli students and staff.
Furthermore, we would like to draw your attention to recent events that demonstrate the potential dangers associated with this
slogan. During the 2023 Israel-Hamas war, British Home Secretary Suella Braverman proposed criminalizing the use of the slogan
in certain contexts, recognizing the potential harm it can cause. Additionally, on October 11, ‘23, Vienna police banned a
demonstration, citing the inclusion of the phrase "from the river to the sea" in invitations, as it was seen as a portrayal of a violation
of Article 2 of the European Convention on Human Rights.
In addition to the use of these derogatory messages, several attendees of the event used hateful wordings and messages towards
Jewish and Israeli bystanders. In one case, a perpetrator aggressively held their bicycles as intended to harm a Jewish MIT student,
stating that “[your] ancestors did not die in the Holocaust so they could kill Palestinians” [See video footage attached]. In another
incident, protesters chanted “one solution, intifada revolution”. In the context of the on-going Israeli-Palestinian conflict, the word
"Intifada" means the armed and violent Palestinian insurrection targeting Israelis, including civilians, which resulted in the killing of
thousands of Israelis in the last few decades.
On Oct. 22nd, a statement by MIT CAA (Coalition Against Apartheid) came to our attention. In this document, MIT CCA states that
they "hold the Israeli regime responsible for all unfolding violence". They later call the October 7th terror attack a "response to
the settler colonial regime", and continue justifying it throughout the document.
In this matter, MIT CAA is justifying the heinous and barbaric crimes committed on Oct 7th. Furthermore, these statements have the
potential to fuel acts of aggression
Overview of the Israeli exhibitors at the 2023 HLTH conference in Las Vegas. Exhibitors included 6Degrees, AppScent, Belong.Life, Datos, Expecting, IntraPosition, Kahun Medical, Kemtai, Maverick, Neteera, QuantaIX, Respiration Scan, Nerivio, Xoltar.
40% of Israeli technology investment is devoted to Life Science. Within that domain, the largest sector is Medical Devices and Digital Health (over 65 percent of companies). In the medical device arena, Israeli scientists and engineers have integrated advanced technologies in electronics, communications and electro-optics to develop world-class innovations in Digital Imaging, Medical Lasers, Telemedicine, Early Diagnostics,
Smart Surgical Equipment and more. Over 600 medical device exporters engaged in a variety of medical application
such as Cardiovascular and Peripheral Vascular, Neurology and Degenerative Diseases, Preparedness and Emergency
Medicine, Intensive Care, Women Health, Orthopedics and Sport Medicine, Gastrointestinal, Infection Control, Ophthalmology, Pain and Wound Management, Oral and Dental Care, Dermatology and Aesthetics
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Presentation by Mark Coticchia, Chief Innovation Officer, Baptist Health, for mHealth Israel community, September, 2023. Baptist Health has internationally renowned centers of excellence in cancer, cardiovascular care, orthopedics and sports medicine, and neurosciences.
A not-for-profit organization supported by philanthropy and committed to its faith-based charitable mission of medical excellence, Recognized by Fortune as one of the 100 Best Companies to Work For in America and by Ethisphere as one of the World’s Most Ethical Companies.Innovation is paramount to health system’s performance and reputation.
Becker’s 2019 Advisory Board survey revealed innovation and technology ranked as the top priority among healthcare finance professionals - up from eighth in 2018. 90% healthcare/life science leaders agree that the pandemic will fundamentally change the way they do business, requiring new products, services, processes, and business models (McKinsey: Innovation Through Crisis Survey). Innovation has been proven to help health systems in many ways. A capability and culture of innovation accomplish numerous goals:
Innovation capability and culture improve the care and work environment. They enhance the reputation through recognition for discoveries made at and through Baptist Health. They aid in the recruitment and retention of top talent. And they help systems harness money that otherwise would be leaving the system – licensing revenues and investment returns and corporate research support and donor revenues. Successful Programs - Common Underpinnings. Innovation as a strategic, institutional priority
Program built on institutional assets and centers of excellence
Experienced, professional team
Technology development and sourcing, Dedicated, long term support. Doing healthcare innovation well at a large enterprise takes a highly specialized team and skill set. Collectively, they need to have deep knowledge of healthcare regulation, medical procedures, patient safety, business development, transactions, business law, innovation markets, entrepreneurship, venture capital, commercialization, tech transfer, organizational change management, and much more. Programs- services, technology management, corporate co-creation, global medical service lines and facilities; Focus on market opportunity vs. technology; Select & concentrate on winners; Operate as a business; Proactive in new company formation; Progress, milestones, preliminary results; Building New Innovation Pathways; Improving Treatment for Cancer Patients; Predicting & Preventing Heart Attacks; Improving Outcomes in Cardiac Care; Enhancing a Culture of Innovation at Baptist Health & South Florida; Cleerly, TriVentures, COTA; Innovation is paramount to health system’s performance and reputation.
Baptist Health has established an innovation function predicated on best practices and tailored to its assets and the opportunities extending from Miami’s economic growth
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Presentation by Yael Klionsky, YEDA, for the mHealth Israel community in September, 2023. Title: Challenges in Academic Technology Transfer. Examples-
Transplantation Immunology and Immunometabolism. Efranat Pharma was developing an anticancer immunotherapy treatment based on a natural plasma protein molecule. From target discovery to clinical validation. Clinical-stage drug discovery and development company utilizing a broadly applicable, predictive
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therapeutics in the field of cancer immunotherapy. To allow SOCIETY to benefit from discoveries made at the academic institution. To enable SCIENTISTS to transfer their new technologies to the market. To create an additional source of INCOME for the INSTITUTE so that more independent research can be conducted. Three important elements that make an idea patentable:
1) The invention must be new: the same idea can’t have been
published before in any form; 2) There must be some inventive step of ‘non-obviousness’.
This can be hard to define and depends on the context; 3) The disclosure in a patent must be sufficient for a skilled
person to reproduce the invention with only routine effort; Technology Transfer Company - modus operandi; OUR PURPOSE- To provoke transformative scientific breakthroughs that will shape the future of humanity; SCIENTIFIC STAFF- 300 Principal investigators, >2,000 Research students and PhDs; 5 FACULTIES – BASIC SCIENCE, Biology, Physics, Biochemistry, Math/CS
Chemistry; Generated IP- 57% in Life Science & Biotech; Among the Highest
Income per Researcher
Worldwide; 1959 (First TTO outside the US); Today- More applications per PI than in most Ivy league universities; Copaxone- >$30B
ANNUAL SALES BASED ON Weizmann IP; 20 new licenses per year and 10 new companies per annum; www.yedarnd.com
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NURTURING INTERNAL INNOVATION, Tech Transfer, EXTERNAL INNOVATION. External- SERVICES & COLLABORATIONS WITH COMPANIES, BIOHOUSE FOR STARTUPS, DIGITAL HEALTH ACCELERATOR); Internal Innovation- NURTURING INTERNAL INNOVATION, HADASSAH SEED FUND, JERUSALEM BIODESIGN PROGRAM; TYPES OF RELATIONS WITH EXTERNAL COMPANIES- CONSULTING, SAB, CLINICAL TRIALS, R&D SERVICES, DATA LICENCE, ALPHA/BETA SITE, PILOTS, DESIGN PARTNERSHIPS.
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micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
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Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
CDSCO and Phamacovigilance {Regulatory body in India}NEHA GUPTA
The Central Drugs Standard Control Organization (CDSCO) is India's national regulatory body for pharmaceuticals and medical devices. Operating under the Directorate General of Health Services, Ministry of Health & Family Welfare, Government of India, the CDSCO is responsible for approving new drugs, conducting clinical trials, setting standards for drugs, controlling the quality of imported drugs, and coordinating the activities of State Drug Control Organizations by providing expert advice.
Pharmacovigilance, on the other hand, is the science and activities related to the detection, assessment, understanding, and prevention of adverse effects or any other drug-related problems. The primary aim of pharmacovigilance is to ensure the safety and efficacy of medicines, thereby protecting public health.
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Muktapishti is a traditional Ayurvedic preparation made from Shoditha Mukta (Purified Pearl), is believed to help regulate thyroid function and reduce symptoms of hyperthyroidism due to its cooling and balancing properties. Clinical evidence on its efficacy remains limited, necessitating further research to validate its therapeutic benefits.
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
2. Given Imaging - Recognized Industry Leader
World Leader in Minimally-Invasive GI Diagnostics
>85% Market share globally [ >95% share in the U.S. ]
One of the largest GI sales and marketing organizations in
North America (nearly 100 sales and marketing professionals
in the US alone)
~5,500 active PillCam customers:
2,750 Americas, 1,000 APJ, 1750 EMEA
Over 2 Million capsules ingested to date
Thousands of lives saved due to the CE [ Capsule Endoscope ]
More than 2,000 PillCam peer-reviewed publications
Strong IP: ~350 registered patents, ~230 pending patents
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4. Given Imaging’s Comprehensive GI
Diagnostic and Monitoring Solutions
The only capsule-based pH test for GERD
PillCam ESO 2
Capsule endoscopy procedure for
Ambulatory pH testing gold standard
visualization of the esophagus
Complete reflux
diagnostic solution for
both capsule and
catheter-based testing
PillCam SB 2
Most widely used capsule
endoscope for visualization of
the entire small bowel
The standard of care in
numerous countries
PillCam COLON 2
Safe, minimally invasive, sedation-
free, patient-friendly modality to
visualize the colon and rectum
PillCam COLON 2 not cleared for use in U.S.
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High-Resolution Manometry
with physiology
visualization and data
analysis software for
identification of motility
disorders
Ingestible, wireless motility capsule
using sensor technology to measure
pH, pressure and temperature from
within the entire GI tract
6. The main technical challenges of Capsule Endoscopy
Power Management
Miniaturization
Fit within capsule form factor
Completion of medical
procedure within allotted time
Battery operation & shelf life
Reading Time
Diagnostic Yield
Facilitation of effective
detection of pathologies by
physicians
Patient-Friendly
Data Transmission
A narrow ‘pipe’ to xfer the video
Ensuring timely
conclusions by the
physician
Two-way data transmission
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Patient comfort before
(prep), during and after
procedure
The Gold
Standard in
Capsule
Endoscopy
7. The Capsule Communication Challenges
High volume data:
up to 35 Frames/sec
Frame/image size: now at ~100K pixels. Next generation may need much more!
Confined carrier Frequency choice
Very high attenuation in the human body above 1GHz
But… our high bandwidth necessitates high frequency
The lower the frequency the worse is a given size antenna’s effectiveness
We should use ISM [ Industrial, Scientific, Medical ] frequency bands
Attempt to fit within narrow bandwidth
Regulatory constraints
Noise immunity
Consume very low power
Battery operated. Needs to last a 10-12 hours procedure
Need cost-effective, medium volume, reliable solution
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8. The frequency range
There are several sub-1GHz ISM bands.
Since we need to support high-bandwidth – the higher the
frequency – the better
The capsule size implies antenna that is smaller than 1 cm.
It is apparent that we lose most of the transmission power due
to antenna frequency mismatch.
Still, the higher the frequency – the better the transmission
In the 750 – 900MHz domain there are ISM bands.
However, they vary from region to region [ US, EMEA, Japan,
China… ]. It will complicate substantially the implementation if
we need to devise a dedicated transmitter/frequency per
region!
The most suitable ISM band that we found, under the above
constraints, is around 434MHz
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9. Coping with the bandwidth challenge
The consumer world migrates to ever-increasing image
quality:
HD TV and PC/Internet quality
Digital Cameras growing M-Pixels count
The GI Physicians migrate to HD Endoscopes and start
expecting HD image quality from Capsule Endoscopy
But… the ‘pipe’ of our communication is narrow [ circa
13MHz ] due to both Regulation and Noise constraints
So… we must employ every trick in the book to squeeze
the utmost of the given ‘pipe’: Modern modulation
and, especially, compression solutions
The capsule is limited in its power budget. Hence, we
seek for asymmetrical compression solutions that do not
exhaust extensive power on the transmitting side
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10. Coping with the low power constraint
As mentioned – wherever possible, the solution is tuned so
that the burden is on the Receiver side and the transmitting
capsule has less power-exhausting tasks to perform.
Since capsule movement in the bowels is intermittent
[ it parks for a while and then speeds up ] – we do not want
to take photos at high rate all the time, but, on the other
hand, do not want to miss pathologies while traveling fast.
Hence: We developed AFR [ Adaptive Frame Rate ] that
detects fast movement and temporarily switches to a Very
High Rate [ 10X ]
All common tricks of power-saving [ turning off modules
while not being used, using low-power manufacturing
process & circuit solutions ]
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11. In summary
The Video Capsule attains effective clinical performance by
making the best out of a highly constrained environment:
Correct selection of the carrier frequency/band
Careful selection of the working-point
Application of asymmetrical compression
Adaptive Frame Rate
Careful low-power design
All the above lead to a Market Leading highly popular product!
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