Incepta pharmaceutical Ltd. is one of the leading pharmaceutical company in Bangladesh. They provide their best effort to produce a quality product. They have modern and sophisticated machinery and all facility required to comply with the GMP.
Incepta pharmaceutical Ltd. is one of the leading pharmaceutical company in Bangladesh. They provide their best effort to produce a quality product. They have modern and sophisticated machinery and all facility required to comply with the GMP.
In-plant Training Report at Ziska Pharmaceuticals Ltd. by~ WaliullahWaliullah Wali
ZISKA PHARMACEUTICAL LTD.
In Plant Training
Training Period: From August 06, 2014 to August 19, 2014Duration: 14 Days
Training Areas:
WarehouseProduction DepartmentQuality Assurance & Quality Control Department Product Development DepartmentMaintenance & Engineering Department
Introduction
In Bangladesh the pharmaceutical sector is one of the most developed hi-tech sectors within the country's economy.
This sector is also providing 97% of the total medicine requirement of the local market.
Recently few new industries have been established with high tech equipment’s and professionals which will enhance the strength of this sector.
Ziska Pharmaceutical Ltd. is one of them.
PROFILE ABOUT ZISKA PHARMACEUTICAL LTD.
Company Name: Ziska Pharmaceutical Ltd.
Factory Location: Karol Surichala, Safipur, Gazipur
Head Office: Nurul tower, 34- Purana Paltan line, Dhaka-1000
Corporate Setup: Private Limited Company.
Manufacturing areas: 146500 sft.
Established Year: 1986
Popular Products OF ZISKA PHARMACEUTICAL LTD.
Engineering department
Engineering department
The Engineering department deals with the complete maintenance of the production and companies total working environment .
The Engineering section of Ziska Pharmaceuticals Ltd. covers the following Utilities :
Production machineries.
Electricity supply
Air Handling
Water supply
Emergency supply
Repairing, restoring and reporting
Worker distribution and pest control.
Engineering department
Utility Service
Electricity:
Required electricity mainly obtained from DESA, incase of load shedding heavy duty generator provide electricity.
Generator:
Name: Cummins
Type: diesel operated.
Capacity: 1750 kilowatt.
Requirement: 1500 kilowatt.
Engineering department
Engineering department
HVAC:
It means Heating Ventilation Air Conditioning (HVAC). It maintains optimum temperature and humidity throughout the factory.
All seeks to provide thermal comfort , acceptable indoor air quality and reasonable installation operation.
Engineering department
HVAC:
Controlling of temperature and Relative Humidity in deferent areas-
Dispensing: 22±2°C 45±5% RH
Solid &Liquid: 22±2°C 55±5% RH
Sterile: 22±2°C 50±5% RH
Low humidity requiring rooms: 22±2°C 25±5% RH
Minimum air change rate:
Class B 30/hr
Class C 30/hr
Class D not less than 15/hr
Engineering department
HVAC system:
Engineering department
HVAC system:
Engineering department
Chiller system:
This system is involved for the production of chilled water which is supplied through the pipe to produce air conditioning system.
Process:
Engineering department
Engineering department
HEPA Filter
High-efficiency particulate air Filter or HEPA filter is an air filter that must remove (from the air that passes through) 99.97% of 0.3 µm size particles.
Smaller and larger particles are filtered at even greater efficiency.
The effi
Development of Suitable Pharmaceutical Dosage forms through Herbal Plant ExtractSriramNagarajan19
In recent years there is a spurt in the interest regarding survival of Ayurvedic forms of medication. In the global perspective, there is a shift towards the use of medicine of herbal origin, as the dangers and the shortcoming of modern medicine have started getting more apparent, majority of Ayurvedic formulation are prepared from herbs. It is the cardinal responsibility of the regulatory authorities to ensure that the consumers get the medication, which guaranteed the purity, safety, potency and efficacy. As a result of this Standardization arise for maintaining a good coordination among the quality of raw herb material, in process materials and in final product. Present study was carried out to standardize different types of formulations using pharmaceutical excepients.
Capsules. Their Types, manufacturing and packaging.pdfShakeelIjaz3
Capsules are solid dosage forms in which the drug substance is enclosed within either a hard or soft soluble shell, usually formed from gelatin.
The capsule may be considered a container drug delivery system that provides a tasteless and odorless dosage form without need for a secondary coating step, as may be required for tablets. Their availability in a wide variety of colors makes capsules aesthetically pleasing. Gelatin is obtained by the partial hydrolysis of collagen obtained from the skin, white connective tissue, and bones of animals.
Gelatin capsule shells may be hard or soft, depending on their composition.
Hard Gelatin Capsules
Soft Gelatin Capsules
The shells may be composed of two pieces, a body and a cap, or they may be composed of a single piece. hard-shell capsules are two piece capsules whereas soft shell capsules are one piece capsules.
Hard Gelatin Capsules:
Most capsule products manufactured today are of the hard gelatin type.
The community pharmacist also uses hard gelatin capsules in theextemporaneous compounding. The empty capsule shells are made of gelatin, sugar, and water.
Normally, hard gelatin capsules contain 13% to 16% of moisture. However, if stored in an environment of high humidity, additional moisture is absorbed by the capsules, and they may become distorted and lose their rigid shape. In an environment of extreme dryness, some of the moisture normally present in the gelatin capsules is lost, and the capsules may become brittle and crumble when handled. Therefore, it is desirable to maintain hard gelatin capsules in an environment free from excessive humidity or dryness.
Advantages for HGC:
Hard gelatin capsules often have been assumed to have better bioavailability than tablets.
Hard shell capsules allow a degree of flexibility of formulation not obtainable with tablets.
Modern capsule filling equipment makes possible the multiple filling of diverse systems such as beads, granules, small tablets and powders.
Hard gelatin capsules are ideally suited for clinical trials and are widely used in preliminary drug studies. For comparative bioequivalence studies tablets can even be hidden in capsules to ensure the test being blinded.
Disadvantages of HGC:
The number of suppliers of shells is limited.
Filling equipment is slower than tableting.
Generally, hard gelatin capsule products tend to be more costly.
Highly soluble salts (e.g., iodides, bromides, and chlorides) generally should not be dispensed in hard gelatin capsules. Their rapid release may cause gastric irritation owing to the formation of a high drug concentration in localized areas.
Manufcaturing of HGC:
Hard gelatin capsule shells are manufactured in two sections, the capsule body and a shorter cap. The two parts overlap when joined, with the cap fitting snugly over the open end of the capsule body. Some capsule shells are designed to lock in place when closed. Hard gelatin shells are manufactured by a process in which stainless steel mold pins are
Tablets: a.Introduction, ideal characteristics of tablets, Classification of tablets. Excipients, Formulation of tablets, granulation methods, compression and processing problems.
ORAL ROUTE OF DRUG ADMINISTRATION_Dr. Jeenal Mistry.pdfDr Jeenal Mistry
Oral Dosage Form practical session mainly for undergraduate students, those are learning competency based with PH 2.1: Demonstrate an understanding of use of various dosage forms(Oral/Local/Parenteral ;Solid/Liquid)
Specific Learning Objectives:
The student should be able to:
•Enlist the common dosage forms used for oral route of administration
•Instruct the patient about the correct method of using an oral dosage form
•Describe the advantages and disadvantages of various dosage forms
In-plant Training Report at Ziska Pharmaceuticals Ltd. by~ WaliullahWaliullah Wali
ZISKA PHARMACEUTICAL LTD.
In Plant Training
Training Period: From August 06, 2014 to August 19, 2014Duration: 14 Days
Training Areas:
WarehouseProduction DepartmentQuality Assurance & Quality Control Department Product Development DepartmentMaintenance & Engineering Department
Introduction
In Bangladesh the pharmaceutical sector is one of the most developed hi-tech sectors within the country's economy.
This sector is also providing 97% of the total medicine requirement of the local market.
Recently few new industries have been established with high tech equipment’s and professionals which will enhance the strength of this sector.
Ziska Pharmaceutical Ltd. is one of them.
PROFILE ABOUT ZISKA PHARMACEUTICAL LTD.
Company Name: Ziska Pharmaceutical Ltd.
Factory Location: Karol Surichala, Safipur, Gazipur
Head Office: Nurul tower, 34- Purana Paltan line, Dhaka-1000
Corporate Setup: Private Limited Company.
Manufacturing areas: 146500 sft.
Established Year: 1986
Popular Products OF ZISKA PHARMACEUTICAL LTD.
Engineering department
Engineering department
The Engineering department deals with the complete maintenance of the production and companies total working environment .
The Engineering section of Ziska Pharmaceuticals Ltd. covers the following Utilities :
Production machineries.
Electricity supply
Air Handling
Water supply
Emergency supply
Repairing, restoring and reporting
Worker distribution and pest control.
Engineering department
Utility Service
Electricity:
Required electricity mainly obtained from DESA, incase of load shedding heavy duty generator provide electricity.
Generator:
Name: Cummins
Type: diesel operated.
Capacity: 1750 kilowatt.
Requirement: 1500 kilowatt.
Engineering department
Engineering department
HVAC:
It means Heating Ventilation Air Conditioning (HVAC). It maintains optimum temperature and humidity throughout the factory.
All seeks to provide thermal comfort , acceptable indoor air quality and reasonable installation operation.
Engineering department
HVAC:
Controlling of temperature and Relative Humidity in deferent areas-
Dispensing: 22±2°C 45±5% RH
Solid &Liquid: 22±2°C 55±5% RH
Sterile: 22±2°C 50±5% RH
Low humidity requiring rooms: 22±2°C 25±5% RH
Minimum air change rate:
Class B 30/hr
Class C 30/hr
Class D not less than 15/hr
Engineering department
HVAC system:
Engineering department
HVAC system:
Engineering department
Chiller system:
This system is involved for the production of chilled water which is supplied through the pipe to produce air conditioning system.
Process:
Engineering department
Engineering department
HEPA Filter
High-efficiency particulate air Filter or HEPA filter is an air filter that must remove (from the air that passes through) 99.97% of 0.3 µm size particles.
Smaller and larger particles are filtered at even greater efficiency.
The effi
Development of Suitable Pharmaceutical Dosage forms through Herbal Plant ExtractSriramNagarajan19
In recent years there is a spurt in the interest regarding survival of Ayurvedic forms of medication. In the global perspective, there is a shift towards the use of medicine of herbal origin, as the dangers and the shortcoming of modern medicine have started getting more apparent, majority of Ayurvedic formulation are prepared from herbs. It is the cardinal responsibility of the regulatory authorities to ensure that the consumers get the medication, which guaranteed the purity, safety, potency and efficacy. As a result of this Standardization arise for maintaining a good coordination among the quality of raw herb material, in process materials and in final product. Present study was carried out to standardize different types of formulations using pharmaceutical excepients.
Capsules. Their Types, manufacturing and packaging.pdfShakeelIjaz3
Capsules are solid dosage forms in which the drug substance is enclosed within either a hard or soft soluble shell, usually formed from gelatin.
The capsule may be considered a container drug delivery system that provides a tasteless and odorless dosage form without need for a secondary coating step, as may be required for tablets. Their availability in a wide variety of colors makes capsules aesthetically pleasing. Gelatin is obtained by the partial hydrolysis of collagen obtained from the skin, white connective tissue, and bones of animals.
Gelatin capsule shells may be hard or soft, depending on their composition.
Hard Gelatin Capsules
Soft Gelatin Capsules
The shells may be composed of two pieces, a body and a cap, or they may be composed of a single piece. hard-shell capsules are two piece capsules whereas soft shell capsules are one piece capsules.
Hard Gelatin Capsules:
Most capsule products manufactured today are of the hard gelatin type.
The community pharmacist also uses hard gelatin capsules in theextemporaneous compounding. The empty capsule shells are made of gelatin, sugar, and water.
Normally, hard gelatin capsules contain 13% to 16% of moisture. However, if stored in an environment of high humidity, additional moisture is absorbed by the capsules, and they may become distorted and lose their rigid shape. In an environment of extreme dryness, some of the moisture normally present in the gelatin capsules is lost, and the capsules may become brittle and crumble when handled. Therefore, it is desirable to maintain hard gelatin capsules in an environment free from excessive humidity or dryness.
Advantages for HGC:
Hard gelatin capsules often have been assumed to have better bioavailability than tablets.
Hard shell capsules allow a degree of flexibility of formulation not obtainable with tablets.
Modern capsule filling equipment makes possible the multiple filling of diverse systems such as beads, granules, small tablets and powders.
Hard gelatin capsules are ideally suited for clinical trials and are widely used in preliminary drug studies. For comparative bioequivalence studies tablets can even be hidden in capsules to ensure the test being blinded.
Disadvantages of HGC:
The number of suppliers of shells is limited.
Filling equipment is slower than tableting.
Generally, hard gelatin capsule products tend to be more costly.
Highly soluble salts (e.g., iodides, bromides, and chlorides) generally should not be dispensed in hard gelatin capsules. Their rapid release may cause gastric irritation owing to the formation of a high drug concentration in localized areas.
Manufcaturing of HGC:
Hard gelatin capsule shells are manufactured in two sections, the capsule body and a shorter cap. The two parts overlap when joined, with the cap fitting snugly over the open end of the capsule body. Some capsule shells are designed to lock in place when closed. Hard gelatin shells are manufactured by a process in which stainless steel mold pins are
Tablets: a.Introduction, ideal characteristics of tablets, Classification of tablets. Excipients, Formulation of tablets, granulation methods, compression and processing problems.
ORAL ROUTE OF DRUG ADMINISTRATION_Dr. Jeenal Mistry.pdfDr Jeenal Mistry
Oral Dosage Form practical session mainly for undergraduate students, those are learning competency based with PH 2.1: Demonstrate an understanding of use of various dosage forms(Oral/Local/Parenteral ;Solid/Liquid)
Specific Learning Objectives:
The student should be able to:
•Enlist the common dosage forms used for oral route of administration
•Instruct the patient about the correct method of using an oral dosage form
•Describe the advantages and disadvantages of various dosage forms
capsules and its types are discussed in this slide. along with their uses and their advantages over one another. preparation of each type is well explained in these slides.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
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Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
263778731218 Abortion Clinic /Pills In Harare ,sisternakatoto
263778731218 Abortion Clinic /Pills In Harare ,ABORTION WOMEN’S CLINIC +27730423979 IN women clinic we believe that every woman should be able to make choices in her pregnancy. Our job is to provide compassionate care, safety,affordable and confidential services. That’s why we have won the trust from all generations of women all over the world. we use non surgical method(Abortion pills) to terminate…Dr.LISA +27730423979women Clinic is committed to providing the highest quality of obstetrical and gynecological care to women of all ages. Our dedicated staff aim to treat each patient and her health concerns with compassion and respect.Our dedicated group ABORTION WOMEN’S CLINIC +27730423979 IN women clinic we believe that every woman should be able to make choices in her pregnancy. Our job is to provide compassionate care, safety,affordable and confidential services. That’s why we have won the trust from all generations of women all over the world. we use non surgical method(Abortion pills) to terminate…Dr.LISA +27730423979women Clinic is committed to providing the highest quality of obstetrical and gynecological care to women of all ages. Our dedicated staff aim to treat each patient and her health concerns with compassion and respect.Our dedicated group of receptionists, nurses, and physicians have worked together as a teamof receptionists, nurses, and physicians have worked together as a team wwww.lisywomensclinic.co.za/
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
3. 0 The supplements are strong dose models in which one or more
medicaments and inert ingredients are surrounded within a small
spend, usually ready from the right type of gelatin.
0 Based upon on their ingredients, the gelatin pills spend might be
hard or soft.
4. Hard capsules
Difficult gelatin supplements are used for attaching strong
medicaments.
Consist of two areas, a body system and a lid.
7. Definition
A tablet is a drug amount type which
consists of a combination of active
substances and excipients, usually in
powdered type, pushed or compressed
from a powdered into a solid amount.
9. •Pharmacologist have ready pills in two primary ways-by using a
product triturate mold or an equipment for pressure.
•Certain excipients are also included to the medicaments in the
ingredients of pills.
• The compacted pills are ready in huge quantities by the large-scale
manufacturing methods
10.
11. Excipients can include:
• diluents
• binders or granulating agents
• Glidants (flow aids) and lubrication,
• Disintergrants
• Sweeteners or flavours
• A plastic coating