1) The study evaluated the effect of different levels of marble dust as cement replacement in concrete hollow blocks (CHB) on physical and mechanical properties. 2) Marble dust was collected from waste sites and used at levels of 0-20% cement replacement. Testing showed 10% replacement produced CHBs with optimal compressive strength and water absorption. 3) Compared to commercial CHBs, 10% marble dust CHBs met strength standards, had lower water absorption, and were estimated to provide annual net income of over $2,500 based on reduced production costs. 4) Using marble dust from waste as a partial cement replacement in CHBs was concluded to provide environmental and economic benefits.