This document discusses man-machine interaction from a historical, present, and future perspective. It begins with examples of early automatons and robots from Chinese, Greek, and Italian history. The document then examines present areas of interaction like prosthetics, robotics, and human-computer interfaces. Several case studies are presented on developments like the Luke arm and Bionic Man Rex. The future sections speculate on developments in areas like self-driving cars, AI surgery, exoskeletons, cyborgs and augmented humans. The document closes by acknowledging both the blessings and potential pitfalls of increasing man-machine interaction and dependence.