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MADHAVI TIPPANI
 400 Kerby street, #308, Arlington, Texas - 76013, USA  Email: madhavi.tippani@mavs.uta.edu  Mobile: +1(469) 525 7794
 BIO MEDICAL ENGINEERING PROFESSIONAL 
Research and laboratory assistant, proficient in imaging and data processing using MATLAB. Experienced in installation of medical devices,
trouble shooting and calibration. Skilled at statistical data analysis using MS Excel, R programming and MATLAB and their documentation.
Detail oriented, team leading ability and passionate to learn about new technologies.
 FUNCTIONAL EXPERTISE and SKILLS 
 Application packages: MATLAB (image reconstruction, image processing and analysis, GUI creation), Statistical data analysis (using ‘R’,
MATLAB and MS Excel), Python, LabVIEW, Solidworks, C, MS Office Suite, Image J, QlikView.
 Others: Optical fiber polishing, Knowledge about GMP, GLP, GCP and FDA Regulations.
 EDUCATION 
The University of Texas at Arlington and the University of Texas South Western Medical Centre at Dallas CGPA-4.0/4.0
Master of Science in Bio-Medical Engineering. May 2016
Jawaharlal Technological University, India CGPA-3.3/4.0
Bachelor of Technology in Bio-Medical Engineering May 2013
 COURSEWORK 
Human Anatomy and Physiology, Bio-Optics Laboratory, Laboratory Principles, Basic Clinical Sciences, Bio-Medical Equipment and Signal
Processing, Statistical Methods, Image Processing and Pattern Recognition, Basic Simulation-MATLAB, Medical Informatics, Python.
 PROFESSIONAL EXPERIENCE 
Graduate Research Assistant - Ophthalmology department, UT South Western Medical Center, Dallas, Texas. Sep’15 - Present
 Installed system software following manufacturer's instruction manual
 Data processing, Data modelling and Data visualization of medical images in MATLAB
 Generating text, Excel, image output files through MATLAB, as diagnostic results
 Observed in vivo experiments, learnt measurement procedures and system protocols and documented the same
 Programmed User defined MATLAB functions for decoding header files to load different medical data like DICOM, Volume files
 GUI creation using MATLAB for quantitative data analysis of 3-Dimensional confocal imaging in vivo
 Interactive 2D and 3D image reconstruction and signal processing using MATLAB
Graduate Research Assistant - Bioengineering department, UT Arlington, Texas. Oct’14 – May’15
 Performed timely administration, calibration and troubleshooting of lab equipment
 Performed Data collection, Data scrubbing, Data analysis, Data modelling and Data visualization using MS-Excel and MATLAB
 Performed repeated Frequency Domain measurements and interpreted the results for real time diagnosis of prostate cancer
 Prepared different concentrations of intra lipid and stocked it for experiments, and maintained lab notes for concentration calculations
 Conducted experiments using 32 laser diode, 4 PMT detector Imagent system to calculate scattering and absorption values of different
phantoms using slope algorithms and documented the results for conclusions
 Designed different probe geometries following predefined principles, for effective signal detection
 Observed and recorded signal output from all probe geometries and drew conclusions for suitable probe designs
 Collaborated with technicians: provided them the timely equipment performance and documented the machine technical errors
 Supported laboratory quality and safety initiatives
Sales Executive -Aspirejobz.com Services Pvt. Ltd., Hyderabad, India. Dec’13 – Jun’14
 Achieved increased productivity as a team lead (team of 4 members)
 Marketed company products and services, thus increasing company sales by 8%
 Implemented improved marketing strategies
Intern - Care Hospitals, Hyderabad, India. May’12 – June’12
 Gained knowledge about the operation of life saving equipment in Bio-Medical department
 Trained on hospital regulations, patient care protocols, hazardous chemicals and medical lab record policies
 Performed installation, service and maintenance of medical equipment and documented their specifications and working
 Monitored equipment in ICU, ICCU and operation theaters in the hospital and observed biological parameters
 Prompt reporting of abnormal working conditions of equipment in all wards to the Bio-Medical department in the hospital
 PROJECTS 
 Image processing and 3D reconstruction of Brain images
Developed MATLAB code to project the montage view of series of brain images and to display the contour map of tumor and brain tissue
for cancer diagnosis.
- Used Image processing techniques like Erosion, Linear transformation, Region growing, Segmentation, and Contour mapping
- The code loads 53 MRI DICOM images of brain and executes User defined functions to display the contrast map of brain and tumor.
- Segmentation of brain tissue from skull and scalp was achieved by selecting three seeds (pixels) from brain region in the image and
overlapping the three images grown from the seeds for an accurate image.
- Also generated 3D view of brain while differentiating brain and tumor with different colors to visualize the approximate position and size
of tumor in the brain. Documented the project results with comments on the code.
 Corneal Image Processing Analytical tool
Developed an analytical tool for corneal diagnosis that generates a text file as an analysis report. This tool, built in MATLAB with a Graphical
User Interface (GUI) is used to study the cellular events of wound healing after a corneal surgery or an infection. Corneal data of mice and
rabbits was collected through in vivo confocal microscope (HRT-RCM).
The tool has features (built with User defined functions) allowing a user to:
- Input Volume files from a confocal microscope of different sizes.
- Projects side, front, top and 3D views of the 2D corneal image stack and pick a desired Region of Interest (ROI) from the stack.
- Perform analysis such as Smoothening with different masks
- Calculate the area of the selected portion of the intensity curve and calculate the epithelial, stromal and endothelial thickness of the cornea.
Currently working on documenting the entire progress of the project, results and writing comments on the code.
• Segmentation of Heart structure from surroundings
Different Segmentation techniques like Thresholding, Region Growing, Erosion, Dilation, Opening and Closing etc. were performed on a
CT slice of a human heart and all the results were stored and compared. Segmentation was performed to examine the contrast enhanced
heart by eliminating the additional structures like bones and parts of large blood vessels of lung surrounding the heart and parts of patient
table.
 Study on effect of cancer severity on lifespan of patients
Formulated a Hypotheses and performed statistical data analysis on the data set containing an assay on cutaneous melanoma (malignant
cancer), to determine if the average lifespan of patients decreased with increase in cancer severity. As a part of Data Analysis Hypotheses
testing was performed in ‘R’. Loaded data into R and segregated it into nodule categories based on disease severity, F-tests and T-tests were
performed on all combinations of categories and thus it was concluded that average lifetime decreased with increased severity. Documented
the results of five number summary, boxplot, normality test and hypotheses tests.
 Study on dependency of patient disease history on improvement of his exercise duration
Performed statistical data analysis on the data set and determined that the percentage improvement of exercise duration is in negative linear
relation with the patient disease history. Hypothesis testing for the linearity is performed in R assuming a 5% level of significance and the
result of negative linearity was rechecked with the plot between the two data variables. The assumptions used to formulate the linear model
where checked and the results were documented.
 Frequency Domain Photon migration in tissue
Absorption coefficient and reduced scattering coefficient of intralipid (which mimics tissue scattering characteristics) are measured using
Frequency Domain optical migration technique. Experiment was setup with 1% concentration intralipid as a medium and a source light of
633nm laser with a frequency of 90MHz was used. Output signal is taken at different source detector separations and amplitude and phase
differences are calculated with the reference signal. Absorption, scattering coefficients are then calculated using slope algorithms and
documented the results and conclusions. Laboratory safety rules for using laser were followed and learned side effects of laser.
 Wireless Data Communication and Energy Transfer for Implantable Devices
Developed a magnetic coil to achieve non-invasive energy transfer into the implantable devices, to avoid multiple surgeries for recharging
the implantable. ‘Witricity’, a phenomenon of magnetic resonance is proposed to exchange energy efficiently between strongly coupled
resonant objects in a certain range. Additionally, RF communication was established with the implantable device using a microcontroller
AT89C52 (programmed using Keil microvision 3) to modify the operational parameters as per the requirements

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Madhavi tippani

  • 1. MADHAVI TIPPANI  400 Kerby street, #308, Arlington, Texas - 76013, USA  Email: madhavi.tippani@mavs.uta.edu  Mobile: +1(469) 525 7794  BIO MEDICAL ENGINEERING PROFESSIONAL  Research and laboratory assistant, proficient in imaging and data processing using MATLAB. Experienced in installation of medical devices, trouble shooting and calibration. Skilled at statistical data analysis using MS Excel, R programming and MATLAB and their documentation. Detail oriented, team leading ability and passionate to learn about new technologies.  FUNCTIONAL EXPERTISE and SKILLS   Application packages: MATLAB (image reconstruction, image processing and analysis, GUI creation), Statistical data analysis (using ‘R’, MATLAB and MS Excel), Python, LabVIEW, Solidworks, C, MS Office Suite, Image J, QlikView.  Others: Optical fiber polishing, Knowledge about GMP, GLP, GCP and FDA Regulations.  EDUCATION  The University of Texas at Arlington and the University of Texas South Western Medical Centre at Dallas CGPA-4.0/4.0 Master of Science in Bio-Medical Engineering. May 2016 Jawaharlal Technological University, India CGPA-3.3/4.0 Bachelor of Technology in Bio-Medical Engineering May 2013  COURSEWORK  Human Anatomy and Physiology, Bio-Optics Laboratory, Laboratory Principles, Basic Clinical Sciences, Bio-Medical Equipment and Signal Processing, Statistical Methods, Image Processing and Pattern Recognition, Basic Simulation-MATLAB, Medical Informatics, Python.  PROFESSIONAL EXPERIENCE  Graduate Research Assistant - Ophthalmology department, UT South Western Medical Center, Dallas, Texas. Sep’15 - Present  Installed system software following manufacturer's instruction manual  Data processing, Data modelling and Data visualization of medical images in MATLAB  Generating text, Excel, image output files through MATLAB, as diagnostic results  Observed in vivo experiments, learnt measurement procedures and system protocols and documented the same  Programmed User defined MATLAB functions for decoding header files to load different medical data like DICOM, Volume files  GUI creation using MATLAB for quantitative data analysis of 3-Dimensional confocal imaging in vivo  Interactive 2D and 3D image reconstruction and signal processing using MATLAB Graduate Research Assistant - Bioengineering department, UT Arlington, Texas. Oct’14 – May’15  Performed timely administration, calibration and troubleshooting of lab equipment  Performed Data collection, Data scrubbing, Data analysis, Data modelling and Data visualization using MS-Excel and MATLAB  Performed repeated Frequency Domain measurements and interpreted the results for real time diagnosis of prostate cancer  Prepared different concentrations of intra lipid and stocked it for experiments, and maintained lab notes for concentration calculations  Conducted experiments using 32 laser diode, 4 PMT detector Imagent system to calculate scattering and absorption values of different phantoms using slope algorithms and documented the results for conclusions  Designed different probe geometries following predefined principles, for effective signal detection  Observed and recorded signal output from all probe geometries and drew conclusions for suitable probe designs  Collaborated with technicians: provided them the timely equipment performance and documented the machine technical errors  Supported laboratory quality and safety initiatives Sales Executive -Aspirejobz.com Services Pvt. Ltd., Hyderabad, India. Dec’13 – Jun’14  Achieved increased productivity as a team lead (team of 4 members)  Marketed company products and services, thus increasing company sales by 8%  Implemented improved marketing strategies Intern - Care Hospitals, Hyderabad, India. May’12 – June’12  Gained knowledge about the operation of life saving equipment in Bio-Medical department  Trained on hospital regulations, patient care protocols, hazardous chemicals and medical lab record policies  Performed installation, service and maintenance of medical equipment and documented their specifications and working  Monitored equipment in ICU, ICCU and operation theaters in the hospital and observed biological parameters  Prompt reporting of abnormal working conditions of equipment in all wards to the Bio-Medical department in the hospital
  • 2.  PROJECTS   Image processing and 3D reconstruction of Brain images Developed MATLAB code to project the montage view of series of brain images and to display the contour map of tumor and brain tissue for cancer diagnosis. - Used Image processing techniques like Erosion, Linear transformation, Region growing, Segmentation, and Contour mapping - The code loads 53 MRI DICOM images of brain and executes User defined functions to display the contrast map of brain and tumor. - Segmentation of brain tissue from skull and scalp was achieved by selecting three seeds (pixels) from brain region in the image and overlapping the three images grown from the seeds for an accurate image. - Also generated 3D view of brain while differentiating brain and tumor with different colors to visualize the approximate position and size of tumor in the brain. Documented the project results with comments on the code.  Corneal Image Processing Analytical tool Developed an analytical tool for corneal diagnosis that generates a text file as an analysis report. This tool, built in MATLAB with a Graphical User Interface (GUI) is used to study the cellular events of wound healing after a corneal surgery or an infection. Corneal data of mice and rabbits was collected through in vivo confocal microscope (HRT-RCM). The tool has features (built with User defined functions) allowing a user to: - Input Volume files from a confocal microscope of different sizes. - Projects side, front, top and 3D views of the 2D corneal image stack and pick a desired Region of Interest (ROI) from the stack. - Perform analysis such as Smoothening with different masks - Calculate the area of the selected portion of the intensity curve and calculate the epithelial, stromal and endothelial thickness of the cornea. Currently working on documenting the entire progress of the project, results and writing comments on the code. • Segmentation of Heart structure from surroundings Different Segmentation techniques like Thresholding, Region Growing, Erosion, Dilation, Opening and Closing etc. were performed on a CT slice of a human heart and all the results were stored and compared. Segmentation was performed to examine the contrast enhanced heart by eliminating the additional structures like bones and parts of large blood vessels of lung surrounding the heart and parts of patient table.  Study on effect of cancer severity on lifespan of patients Formulated a Hypotheses and performed statistical data analysis on the data set containing an assay on cutaneous melanoma (malignant cancer), to determine if the average lifespan of patients decreased with increase in cancer severity. As a part of Data Analysis Hypotheses testing was performed in ‘R’. Loaded data into R and segregated it into nodule categories based on disease severity, F-tests and T-tests were performed on all combinations of categories and thus it was concluded that average lifetime decreased with increased severity. Documented the results of five number summary, boxplot, normality test and hypotheses tests.  Study on dependency of patient disease history on improvement of his exercise duration Performed statistical data analysis on the data set and determined that the percentage improvement of exercise duration is in negative linear relation with the patient disease history. Hypothesis testing for the linearity is performed in R assuming a 5% level of significance and the result of negative linearity was rechecked with the plot between the two data variables. The assumptions used to formulate the linear model where checked and the results were documented.  Frequency Domain Photon migration in tissue Absorption coefficient and reduced scattering coefficient of intralipid (which mimics tissue scattering characteristics) are measured using Frequency Domain optical migration technique. Experiment was setup with 1% concentration intralipid as a medium and a source light of 633nm laser with a frequency of 90MHz was used. Output signal is taken at different source detector separations and amplitude and phase differences are calculated with the reference signal. Absorption, scattering coefficients are then calculated using slope algorithms and documented the results and conclusions. Laboratory safety rules for using laser were followed and learned side effects of laser.  Wireless Data Communication and Energy Transfer for Implantable Devices Developed a magnetic coil to achieve non-invasive energy transfer into the implantable devices, to avoid multiple surgeries for recharging the implantable. ‘Witricity’, a phenomenon of magnetic resonance is proposed to exchange energy efficiently between strongly coupled resonant objects in a certain range. Additionally, RF communication was established with the implantable device using a microcontroller AT89C52 (programmed using Keil microvision 3) to modify the operational parameters as per the requirements