A 30-year-old male patient presented to the hospital with left lower abdominal pain, bloody diarrhea, and weight loss for the past three days. On examination, he had slight tenderness in the left iliac fossa. His symptoms, lab results, and colonoscopy findings were consistent with a diagnosis of ulcerative colitis. Ulcerative colitis is an autoimmune disease that causes inflammation of the colon's mucosal lining and is characterized by diarrhea, rectal bleeding, abdominal pain, and weight loss. Treatment involves medications like 5-aminosalicylic acid to reduce inflammation of the intestinal lining.

2. CONTENTS …
SOPEPEL
• Subjective
• Objective
Ulcerative
colitis
TREATMENT
• Diagnose
• Treatment
• Definition
• epidemiology
• pathogenesis
• Sign / symptom

3. SOEPEL …
SUBJECTIVE :
A MIDDLE AGE MALE PATIENT ENTER THE HOSPITAL WITH LEFT LOWER
ABDOMINAL PAIN .
HISTORY:
MR.A 30 YEARS OLD, HAVE ABDOMINAL PAIN SINCE 3 DAYS AGO, BLOODY
DIARRHEA, AND LOSS OF WEIGHT.
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4. PAIN ANALYSIS
1.
SITE: L. ILEAC FOSSE.
2.
ONSET:GRADUATE.
3.
CHARACTER: SHARP.
4.
RADIATION: --
5.
ASSOCIATED FACTORS: DURING DEFECATION.
6.
TIME/DURATION: ONE WEEK.
7.
EXAGGERATED AND RELIEVING FACTORS: --
8.
SEVERITY: MODERATE.

5. SOEPEL …
•O
•E
•P
•E
•L
BJECT: GENERAL ABDOMINAL EXAMINATION
VALUATION “DD, CROHN’S DISSEASE, INFLAMMATORY BOWEL SYDROME .
LAN: BLOOD TEST, STOOL CULTURE, COLONOSCOPY, X-RAY.
LABORATION: DRUG THERAPY .
EARNING GOAL: ULCERATIVE COLITIS.
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6. DEFINITION …
COLITIS IS AN AUTOIMMUNE DISEASE OF AN
UNKNOWN CAUSE CAUSING INFLAMMATION OF THE
MUCOSA OF THE RECTUM, IS CONFINED TO THE
COLON, WITH OCCASIONAL INVOLVEMENT OF
THE ILEUM.
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7. EPIDEMIOLOGY …
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8. SITES …
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9. HISTOLOGY …
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10. PATHOGENESIS …
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11. CLINICAL FEATURES
• DIARRHEA
• RECTAL BLEEDING
• TENESMUS
• PASSAGE OF MUCUS
• ABDOMINAL PAIN
• OTHER SYMPTOMS: ANOREXIA, NAUSEA, VOMITING, FEVER, WEIGHT LOSS
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12. SEVERITY …
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13. COMPLICATION …
• SEVERE BLEEDING
• A HOLE IN THE COLON (PERFORATED COLON)
• SEVERE DEHYDRATION
• OSTEOPOROSIS
• INFLAMMATION OF SKIN, JOINTS AND EYES
• AN INCREASED RISK OF COLON CANCER
• A RAPIDLY SWELLING COLON (TOXIC MEGACOLON)
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14. EXTRA-INTESTINAL MANIFESTATIONS
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15. DIAGNOSIS
EXAMINATION:
ABDOMEN
RECTAL
SLIGHTLY DISTANT OR TENDER PALPITATION
PRESENCE OF BLOOD
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16. INVESTIGATION …
• BLOOD TEST: IRON DEFICIENCY ANEMIA WBC AND PALTELET ARE RAISED.
• STOOL CULTURE AND CLOSTRIDIUM DIFFICILE TOXIN: TO EXCLUDE
INFECTIVE CAUSES OF COLITIS.
• COLONOSCOPY
• X-RAY: TO EXCLUDE COLONIC DILATATION
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17. MANAGEMENT …
MEDICATION:
• 5-AMINO SALICYLIC ACID (5-ASA)/MESALAMINE
• DIFFERENT PREPARATIONS OF 5-ASA INCLUDE:
ASACOL, ROWASA, PENTASA (TRADENAMES)
• 5-ASA IS A TOPICALLY ACTIVE ANTI-INFLAMMATORY AGENT FOR INFLAMED
INTESTINAL MUCOSA.
• CHRONIC 5-ASA REQUIRES FOLATE THERAPY.
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18. REFERENCES …
• KUMAR AND CLARLK 8TH EDITION.
• OXFORFD OF GENERAL PRACTICE 2ND EDITION.
• ULCERATIVE COLITIS “ DR. MHD SEDDIQUE “ LECTURE
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