Long vs short read sequencing. Long read sequencing technology is po.pdf
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Long vs short read sequencing. Long read sequencing technology is poised to replace short read sequencing (e.g. Illumina). a. What is the typical read length in short read sequencing, and what is the read length range for long range sequencing? b. What are the downsides for using short read sequencing for genome assembly/SNP calling, and RNA isoform discovery/quantification? c. Which genomic protocols and/or applications are expected to benefit the most from long read sequencing? 1. Sequencing DNA that are accessible (e.g. ATAC-seq/DNASE-seq). 2. Measuring histone modifications (e.g. for ChIP-seq). 3. Measuring gene expression levels. 4. Measuring messenger RNA isoform diversity. 5. DNA sequencing for genome assembly. 6. DNA sequencing for variant calling (SNPs? Large structural variants?). d. Bulk versus single cell. Most if not all genomics protocols described have been or can be adapted to probe gene regulation in a single cell. What are some of the difficulties that make measuring DNA, RNA, and/or protein more difficult in single cells? Select the answer that applies. 1. The small number of molecules (DNA, RNA, protein) in a single cell is the general limiting factor for single cell genomics. 2. Handling single cells is a lot more difficult because they tend to undergo apoptosis. c. Making sure that you actually sequence one cell instead of multiple cells. 3. Finding a good way to dissociate cells is difficult for many tissue-types. e. You attend a seminar and hear about a super cool approach called SUPER AWESOME DNA- seq (SAD-seq). SAD-seq is able to measure, at nucleotide resolution, DNA bases that interact with other DNA bases (DNA-DNA interactions). The speaker shows data that demonstrate SAD seqs ability to recapitulate enhancer and promoter activity in two cancer-relevant cell lines (e.g. HeLa cells and K562). The speaker further shows that SAD-seq can be used to identify differentially expressed genes by comparing promoter activation. SAD-seq can do it all! Naturally, you start to wonder whether you should be using SAD-seq in your project, or whether you should start developing methods for analyzing SAD-seq. What are some important questions you should ask yourself before jumping head in?.
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de un miembro..
Los patrones caracter�sticos del ciclo econ�mico de valle, expansi�n.pdf
Los patrones caractersticos del ciclo econmico de valle, expansin, pico y contraccin son:
Peridico
Recurrente
De duracin similar
Todo lo anterior
Durante la fase de contraccin de un ciclo econmico, lo ms probable es que:
Los indicadores de inflacin se mantienen estables
La actividad econmica agregada est disminuyendo
Disminuye la preferencia de los inversores por los valores gubernamentales.
Todo lo anterior
Un pico econmico est ms estrechamente asociado con:
Aceleracin de la inflacin
Desempleo estable
Disminucin del gasto de capital
Todo lo anterior.
Los pa�ses de bajos ingresos tienen un INB per c�pita de $1,005 o me.pdf
Los pases de bajos ingresos tienen un INB per cpita de $1,005 o menos. Las caractersticas
generales que comparten los pases en este nivel de ingreso incluyen todas las siguientes excepto:
A.alta poblacin agrcola.
B.menos dedicados a la agricultura.
C. fuerte dependencia de la ayuda exterior.
D.altas tasas de natalidad.
E.disturbios polticos..
Los museos p�blicos a veces piden a los patrocinadores que donen una.pdf
Los museos pblicos a veces piden a los patrocinadores que donen una tarifa mnima de admisin,
pero algunas personas hacen trampa. Supongamos que los investigadores pegaron
alternativamente dos carteles sobre el punto de donacin en cierto museo pblico. Durante una
semana, fue una imagen de flores durante la otra, fue un par de ojos fijos. Descubrieron que la
donacin promedio fue significativamente mayor cuando el cartel de los ojos estaba colocado que
cuando las flores estaban all.
Identifique quin, qu y la poblacin ms grande para este estudio..
Los loci A y B tienen una frecuencia de recombinaci�n del 5 por cien.pdf
Los loci A y B tienen una frecuencia de recombinacin del 5 por ciento. Los loci A y C tienen una
frecuencia del 15 por ciento. Los loci A y D tienen una frecuencia del 22 por ciento. El lugar
geomtrico que probablemente sea el ms distante del lugar geomtrico D es _______.
a. lugar B
b. locus C
C. lugar A
d. locus D
El cuerpo de Barr se refiere a genes que estn estrechamente vinculados?
a. FALSO
b. Verdadero
Si una Drosophila tiene un par de cromosomas X y 3 pares de autosomas, cul es el fenotipo?
a. Femenino
b. Masculino
C. intersexual
La huella digital gentica NO es til para identificar _______.
a. padre de un nio
b. personas despus de la muerte masiva debido a un desastre natural
C. criminales involucrados en violaciones, asesinatos, etc.,
d. inmigrantes ilegales
mi. si tiene el alelo para un trastorno especfico como fibrosis qustica, parkinson, daltonismo, etc..
Los mercados sociales act�an como ______________ en l�nea aprovechan.pdf
Los mercados sociales actan como ______________ en lnea aprovechando el poder de las redes
sociales para la introduccin, compra y venta de productos, servicios y recursos.
intermediarios
carritos de compra
comunidades
consumo colaborativo
Triturar
intermediarios
carritos de compra
comunidades
consumo colaborativo
Triturar.
Los ingresos de una entidad normalmente se miden por los valores de .pdf
Los ingresos de una entidad normalmente se miden por los valores de cambio de los activos o
pasivos involucrados. El reconocimiento de los ingresos no se produce hasta que
a- Una obligacin de desempeo se satisface en el tiempo.
b- Los productos o servicios se intercambian por dinero en efectivo o se reclama dinero en
efectivo.
c- Se transmite un bien.
d- Una obligacin de desempeo se satisface mediante la transferencia del control de un activo..
Los impuestos a la propiedad sobre las instalaciones de fabricaci�n .pdf
Este documento no contiene información sustancial para resumir. Consiste en una tabla con opciones múltiples que no proporcionan contexto.
Los hombres tienen m�s probabilidades de sufrir una enfermedad o tra.pdf
Los hombres tienen ms probabilidades de sufrir una enfermedad o trastorno relacionado con el
sexo porque:
los machos no tienen cromosomas sexuales
los machos tienen menos ADN
Los machos tienen el cromosoma Y que causa enfermedades.
los machos tienen solo 1 cromosoma X
A.
los machos no tienen cromosomas sexuales
B.
los machos tienen menos ADN
C.
Los machos tienen el cromosoma Y que causa enfermedades. D.
los machos tienen solo 1 cromosoma X.
Los helechos, un tipo de planta, pasan por una alternancia de genera.pdf
Los helechos, un tipo de planta, pasan por una alternancia de generaciones. Cul de las siguientes
es correcta acerca de este proceso?
A) La mitosis ocurre en la generacin de esporofitos para generar gametos.
B) La generacin de gametofitos consta de clulas diploides.
C) Las plantas esporofitas producen espermatozoides y las plantas gametofitas producen vulos.
D) Las clulas somticas pueden ser haploides o diploides, segn la generacin.
E) Las clulas haploides sufrirn meiosis para producir espermatozoides u vulos..
Los ganglios linf�ticos funcionan como puntos de encuentro entre las.pdf
Los ganglios linfticos funcionan como puntos de encuentro entre las clulas dendrticas portadoras
de antgeno que llegan del tejido y los linfocitos B y T recirculantes. Mientras que las clulas
dendrticas provenientes del tejido ingresan al ganglio linftico a travs de los vasos linfticos
aferentes, los linfocitos recirculantes ingresan al ganglio linftico:
A. Tambin del lquido linftico que drena el tejido.
B. Directamente de su rgano linfoide primario donde se desarrollan
C. De la sangre atravesando las vnulas endoteliales altas
D. Al quedar atrapado en el folculo linfoide por los macrfagos residentes
E. Al ser transportado all por clulas dendrticas..
Los estudios de casos de gesti�n de proyectos se basan en el PMI 201.pdf
Los estudios de casos de gestin de proyectos se basan en el PMI 2019
Proyecto del Ao: Embraer.
Debe leer el estudio de caso detenidamente y analizar el proyecto en trminos de:
1. La Estructura Organizacional Matriz Fuerte de la Compaa y su relacin con el proyecto y
gestin de programas.
2. Objetivos Estratgicos de la Organizacin.
3. Beneficios para la Organizacin.
4. Cmo Program Management / Project Management facilit la gestin, seguimiento y
control del proyecto.
5. Gobernanza del Proyecto, involucrando el nivel de seguimiento y control sobre sus procesos.
Con base en el anlisis crtico del estudio de caso, las lecturas de la presentacin, incluyendo pero
no
limitado a fuentes vlidas basadas en Internet, debe producir un informe de una pgina para los
siguientes
pregunta:
Discutir la influencia de la fuerte estructura organizativa matricial de la empresa, la gestin del
programa
y los procesos y marcos de gobernanza tienen sobre el proyecto asumido por Embraer. Cules
fueron los
Se lograron los beneficios para la Organizacin y los Factores de xito del Proyecto?
CASO:
Como cualquier empresa aeroespacial lder, Embraer est impulsada por la misin de apuntar ms
alto. La compaa se ubica como uno de los fabricantes de aviones comerciales ms grandes del
mundo, pero con motores ms nuevos y ms eficientes en el consumo de combustible que
amenazan con dejar obsoletos a sus aviones ms vendidos, Embraer lanz un proyecto para lanzar
una nueva familia de aviones, y rpido.
Iniciado en 2013, el programa E2 de US$1.700 millones fue diseado para reinventar los E-Jets
caractersticos de la compaa, entregando un avin de prxima generacin para aerolneas regionales
de todo el mundo. En comparacin con la serie E1 existente, los nuevos jets tendran motores ms
potentes, una arquitectura de ala ms aerodinmica, controles de vuelo de ltima generacin e
interiores mejorados con el objetivo de brindar una experiencia de referencia al cliente.
Pero el equipo tuvo que entregar los nuevos aviones en un tiempo rcord. Los lderes del proyecto
de Embraer establecieron un objetivo ambicioso para entregar el primer modelo, el E190-E2, a
su cliente de lanzamiento en solo cinco aos, al menos dos aos ms rpido que cualquier otro avin
de su generacin. Si el equipo poda lograrlo, el programa E2 prometa ayudar a las aerolneas
regionales de todo el mundo a aumentar sus mrgenes gastando menos en costos de combustible y
atrayendo a ms pasajeros. Pero haba riesgos masivos para Embraer.
Tena que estar listo a tiempo, porque imagina que cuando te atrasas un ao, nadie querra la
generacin anterior, dice Lus Carlos Affonso, vicepresidente senior de estrategia e innovacin,
Embraer, So Jos dos Campos, Brasil. . Durante un ao no tendramos el 50 por ciento de nuestros
ingresos, por lo que sera un gran impacto.
Lus Carlos Affonso, Embraer, So Jos dos Campos, Brasil
El tiempo vuela
Junio de 2013: el directorio de Embraer aprueba el plan de negocios E2.
Octubre de 2014: comienza la fabricacin de la primera pieza .
Los estados financieros de todo el gobierno benefician a los usuar.pdf
Los estados financieros de todo el gobierno benefician a los usuarios al permitirles hacer todo lo
siguiente excepto:
Opcin multiple
A. Determinar si la posicin financiera general del gobierno mejor o se deterior durante el perodo
del informe.
B. Comprender el costo de brindar servicios a la ciudadana.
C. Ver cmo el gobierno financia sus programas.
D. Identificar al funcionario gubernamental responsable de administrar cada fondo.
Comprender la medida en que el gobierno ha invertido en bienes de capital..
Los especialistas en marketing incorporan mensajes encubiertos en an.pdf
Los especialistas en marketing incorporan mensajes encubiertos en anuncios o empaques de los
que los consumidores no son conscientes, pero que afectan su comportamiento. Esta tcnica
empleada por los especialistas en marketing tiene como objetivo ________ de un consumidor.
a.
atencin selectiva
b.
distorcin selectiva
C.
percepcin subliminal
d.
atencin voluntaria
mi.
retencin selectiva.
Los estados financieros de Rukavina Corporation son los siguientes .pdf
Los estados financieros de Rukavina Corporation son los siguientes:
348
308
$475
$413
177
62
$475
$413
403
134
78
$135
Los dividendos en efectivo fueron de $20. La empresa no enajen ninguna propiedad, planta y
equipo. No emiti ningn bono pagadero ni recompr ninguna de sus propias acciones ordinarias.
Las siguientes preguntas se refieren al estado de flujos de efectivo de la empresa.
$(20)
$(93)
$(60)
$14 Corporacin Rukavina
Balance Comparativo Finalizando
Balance Comienzo
BalanceActivos: Efectivo y equivalentes de efectivo $33 $30 Cuentas por cobrar 84 81
Inventario 43 40 Propiedad, planta y equipo 663 570 Menos: depreciacin acumulada
348
308 Los activos totales
$475
$413Pasivos y capital contable: Cuentas por pagar $63 $70 Obligaciones con el pblico 140 200
Acciones comunes 95 81 Ganancias retenidas
177
62 Pasivo total y capital contable
$475
$413.
Los elementos de la agencia aparente son A confianza en la repre.pdf
Los elementos de la agencia aparente son:
A: confianza en la representacin consciente o implcita de un director de que una persona es su
agente
B: Autorizacin expresada ya sea verbalmente o por escrito de un agente
C: Cuando el principal se apoya en la confirmacin expresa o verbal del agente de que desea
entrar en una relacin de agencia.
D: Ninguna de las respuestas es correcta..
Los empleados primero�. Ese es el valor cultural m�s importante y cr.pdf
Este documento describe la filosofía de "los empleados primero" del CEO de HCL Technologies, Vineet Nayar. Bajo su liderazgo, HCL ha invertido su estructura organizacional para dar más poder a los empleados de primera línea y aumentar la inversión en el desarrollo de los empleados. Parte clave de esta filosofía es un sistema de "pago de confianza" que ofrece salarios fijos más altos en lugar de bonos variables. Aunque mantener esta cultura durante la recesión fue difícil, HCL no despidió
Los enfoques de Teaming que se usan en los grupos de LinkedIn normal.pdf
Los enfoques de Teaming que se usan en los grupos de LinkedIn normalmente incluyen
conexiones para:
Grupo de opciones de respuesta
Ajuste de cartera, asociaciones profesionales y contribuciones de la comunidad local
Temas de la industria, categoras VIP y combinacin de experiencia
Intereses de noticias, coincidencia de personajes e intereses de pasatiempos
Formacin de equipos verticales, intercambio de similitudes de productos y coincidencias
demogrficas
Coincidencia psicogrfica, alcance de clientes y oportunidades de venta.
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The webinar may also give some examples on how nonprofits can best leverage Walmart Business+.
The event will cover the following::
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Chapter wise All Notes of First year Basic Civil Engineering
Syllabus
Chapter-1
Introduction to objective, scope and outcome the subject
Chapter 2
Introduction: Scope and Specialization of Civil Engineering, Role of civil Engineer in Society, Impact of infrastructural development on economy of country.
Chapter 3
Surveying: Object Principles & Types of Surveying; Site Plans, Plans & Maps; Scales & Unit of different Measurements.
Linear Measurements: Instruments used. Linear Measurement by Tape, Ranging out Survey Lines and overcoming Obstructions; Measurements on sloping ground; Tape corrections, conventional symbols. Angular Measurements: Instruments used; Introduction to Compass Surveying, Bearings and Longitude & Latitude of a Line, Introduction to total station.
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Chapter 4
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Chapter 5
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Chapter 6
Environmental Engineering: Environmental Pollution, Environmental Acts and Regulations, Functional Concepts of Ecology, Basics of Species, Biodiversity, Ecosystem, Hydrological Cycle; Chemical Cycles: Carbon, Nitrogen & Phosphorus; Energy Flow in Ecosystems.
Water Pollution: Water Quality standards, Introduction to Treatment & Disposal of Waste Water. Reuse and Saving of Water, Rain Water Harvesting. Solid Waste Management: Classification of Solid Waste, Collection, Transportation and Disposal of Solid. Recycling of Solid Waste: Energy Recovery, Sanitary Landfill, On-Site Sanitation. Air & Noise Pollution: Primary and Secondary air pollutants, Harmful effects of Air Pollution, Control of Air Pollution. . Noise Pollution Harmful Effects of noise pollution, control of noise pollution, Global warming & Climate Change, Ozone depletion, Greenhouse effect
Text Books:
1. Palancharmy, Basic Civil Engineering, McGraw Hill publishers.
2. Satheesh Gopi, Basic Civil Engineering, Pearson Publishers.
3. Ketki Rangwala Dalal, Essentials of Civil Engineering, Charotar Publishing House.
4. BCP, Surveying volume 1
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Denis is a dynamic and results-driven Chief Information Officer (CIO) with a distinguished career spanning information systems analysis and technical project management. With a proven track record of spearheading the design and delivery of cutting-edge Information Management solutions, he has consistently elevated business operations, streamlined reporting functions, and maximized process efficiency.
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Date: May 29, 2024
Tags: Information Security, ISO/IEC 27001, ISO/IEC 42001, Artificial Intelligence, GDPR
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RHEOLOGY Physical pharmaceutics-II notes for B.pharm 4th sem students
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