This document discusses using Web 2.0 tools and technologies to differentiate instruction and address 21st century learning standards. It provides examples of tools like Xtranormal, Show Me, QR codes, Wordle, Tagxedo, MakeBeliefsComix, Juxio, MyHeritage and Wallwisher that can be used for differentiated projects. Students are given choice in the tools they use through a Tech Tac Toe board. Differentiating instruction allows all students to learn in ways that engage their individual learning styles.