This document lists 38 published works by Dr. Sven Korte, including research papers, book chapters, conference abstracts and posters presented between 1996-2013. The publications cover a range of topics including ecological studies of starfish populations, feasibility studies of intravenous infusion and port catheter techniques in marmoset monkeys, and reference data for marmosets and cynomolgus monkeys. Many of the publications were presented at annual conferences of the Society of Toxicology, Japanese Society of Toxicology, and other scientific meetings.
Protein was extracted from muscles of Channa striatus and attempts were
made to evaluate in vitro antibacterial activity against clinical bacterial isolates. The
higher concentration of protein (100μg/ml) extracts exhibited a pronounced activity
against Pseudomonas aeruginosa (21 mm), Proteus vulgaris (19 mm), Citrobacter sp
(19 mm), Klebsiella pneumoniae (18 mm), Micrococcus sp (17 mm), Bacillus subtilis (16
mm), Staphylococcus aureus (15 mm), E. coli (14 mm) and Serratia marcescens (5
mm). The minimum inhibitory concentration and minimum bactericidal concentration
were found to be 20-40 μg/ml and 80-100 μg/ml respectively for the extracts of
Channa striatus protein against test organisms. This study confirms that C. striatus fish
protein extracts possess antibacterial activity against a wide range of microbes and
justified that it could be used in the traditional medicine as a remedy for the
treatment of bacterial diseases.
American Journal of Bioterrorism, Biosecurity and Biodefense is an international scholarly peer reviewed Open Access journal, aims to promote the research in all the related fields of Bioterrorism, Biosecurity and Biodefence.
American Journal of Bioterrorism, Biosecurity and Biodefense is a comprehensive Open Access peer reviewed scientific Journal that covers multidisciplinary fields. We provide limitless access towards accessing our literature hub with colossal range of articles. The journal aims to publish high quality varied article types such as Research, Review, Short Communications, Case Reports, Perspectives (Editorials), Clinical Images.
American Journal of Bioterrorism, Biosecurity and Biodefense support the scientific modernization and enrichment in Bioterrorism, Biosecurity and Biodefense research community by magnifying access to peer reviewed scientific literary works. Austin also brings universally peer reviewed member journals under one roof thereby promoting knowledge sharing, collaborative and promotion of multidisciplinary science.
Ethnobotanical uses of wild flora and fungi on the circum-Sicilian island of ...Cassandra Quave
This is a presentation given at the 2015 meeting of the Society for Economic Botany.
Abstract:
In 1969, Galt and Galt conducted an ethnobotanical survey [1] in the community of Khamma on the circum-Sicilian volcanic island of Pantelleria, located 67 km from the Tunisian coast. Since then, a number of botanical studies concerning the local wild flora and cultivation of the zibebo grape and capers have been conducted, but none have investigated traditional ecological knowledge regarding the use of wild plants and fungi. Here, 45 years later, we revisit this topic, examining the current day knowledge and practices concerning wild plants and fungi on the island. A total of 42 in-depth interviews were conducted in June 2014 in six communities. All interviews were conducted in person in Italian with prior informed consent. We employed two primary means of eliciting responses concerning traditional practices; informants were asked to: 1) free-list the most commonly used plants for wild foods, general medicine, and skin remedies; and 2) view and discuss a booklet composed of photos of taxa listed in the Galt study.
A total of 86 botanical and 19 fungal taxa representing 54 families were cited by the study participants. While many plant-based traditions have disappeared from daily practice, especially those related to traditional fishing and hunting, they remain in the memories of the eldest subset of the population. For example, one of the most pervasive species in the landscape, Opuntia ficus-indica, has current day uses that persist (e.g., food source and shade source for cultivated vegetables), but its past applications were much more diverse, and included manipulation into hunting snares for birds. Other predominant flora included a number of Euphorbia spp., whose toxic latex was regularly used as a fish poison. Fungi, on the other hand, represent an important source of wild food today, and are widely recognized and regularly consumed. In conclusion, we have found that traditional e knowledge remains important to everyday practices of Pantescans, ranging in applications from wild foods, agricultural tools, and traditional medicines.
Antagonism of lactic acid bacteria against pathogenic agents not related to g...IJERA Editor
Oar researchhas provedthat lactic acid bacteria possess the wide spectrum of antagonistic activity. They inhibit the
growth of not only agents of intestinal infections but also agents ofdiseases not related to gastrointestinal tract.
Protein was extracted from muscles of Channa striatus and attempts were
made to evaluate in vitro antibacterial activity against clinical bacterial isolates. The
higher concentration of protein (100μg/ml) extracts exhibited a pronounced activity
against Pseudomonas aeruginosa (21 mm), Proteus vulgaris (19 mm), Citrobacter sp
(19 mm), Klebsiella pneumoniae (18 mm), Micrococcus sp (17 mm), Bacillus subtilis (16
mm), Staphylococcus aureus (15 mm), E. coli (14 mm) and Serratia marcescens (5
mm). The minimum inhibitory concentration and minimum bactericidal concentration
were found to be 20-40 μg/ml and 80-100 μg/ml respectively for the extracts of
Channa striatus protein against test organisms. This study confirms that C. striatus fish
protein extracts possess antibacterial activity against a wide range of microbes and
justified that it could be used in the traditional medicine as a remedy for the
treatment of bacterial diseases.
American Journal of Bioterrorism, Biosecurity and Biodefense is an international scholarly peer reviewed Open Access journal, aims to promote the research in all the related fields of Bioterrorism, Biosecurity and Biodefence.
American Journal of Bioterrorism, Biosecurity and Biodefense is a comprehensive Open Access peer reviewed scientific Journal that covers multidisciplinary fields. We provide limitless access towards accessing our literature hub with colossal range of articles. The journal aims to publish high quality varied article types such as Research, Review, Short Communications, Case Reports, Perspectives (Editorials), Clinical Images.
American Journal of Bioterrorism, Biosecurity and Biodefense support the scientific modernization and enrichment in Bioterrorism, Biosecurity and Biodefense research community by magnifying access to peer reviewed scientific literary works. Austin also brings universally peer reviewed member journals under one roof thereby promoting knowledge sharing, collaborative and promotion of multidisciplinary science.
Ethnobotanical uses of wild flora and fungi on the circum-Sicilian island of ...Cassandra Quave
This is a presentation given at the 2015 meeting of the Society for Economic Botany.
Abstract:
In 1969, Galt and Galt conducted an ethnobotanical survey [1] in the community of Khamma on the circum-Sicilian volcanic island of Pantelleria, located 67 km from the Tunisian coast. Since then, a number of botanical studies concerning the local wild flora and cultivation of the zibebo grape and capers have been conducted, but none have investigated traditional ecological knowledge regarding the use of wild plants and fungi. Here, 45 years later, we revisit this topic, examining the current day knowledge and practices concerning wild plants and fungi on the island. A total of 42 in-depth interviews were conducted in June 2014 in six communities. All interviews were conducted in person in Italian with prior informed consent. We employed two primary means of eliciting responses concerning traditional practices; informants were asked to: 1) free-list the most commonly used plants for wild foods, general medicine, and skin remedies; and 2) view and discuss a booklet composed of photos of taxa listed in the Galt study.
A total of 86 botanical and 19 fungal taxa representing 54 families were cited by the study participants. While many plant-based traditions have disappeared from daily practice, especially those related to traditional fishing and hunting, they remain in the memories of the eldest subset of the population. For example, one of the most pervasive species in the landscape, Opuntia ficus-indica, has current day uses that persist (e.g., food source and shade source for cultivated vegetables), but its past applications were much more diverse, and included manipulation into hunting snares for birds. Other predominant flora included a number of Euphorbia spp., whose toxic latex was regularly used as a fish poison. Fungi, on the other hand, represent an important source of wild food today, and are widely recognized and regularly consumed. In conclusion, we have found that traditional e knowledge remains important to everyday practices of Pantescans, ranging in applications from wild foods, agricultural tools, and traditional medicines.
Antagonism of lactic acid bacteria against pathogenic agents not related to g...IJERA Editor
Oar researchhas provedthat lactic acid bacteria possess the wide spectrum of antagonistic activity. They inhibit the
growth of not only agents of intestinal infections but also agents ofdiseases not related to gastrointestinal tract.
El lunes 23 de octubre de 2017 celebramos una jornada en la Fundación Ramón Areces sobre Microbiota Intestinal: Implicaciones en la Salud y Enfermedad.
Trends in Antibiotic Resistance of Vibrio Cholerae Isolates in Kenya (2006 - ...paperpublications3
Abstract: The evolution of antibiotic resistance was studied among revived Vibrio cholerae strains which were previously archived at -800c between 2006 and 2015. Antibiotic susceptibility testing (AST) on 12 antimicrobials; ampicillin (10µg), cefpodoxime (10 µg), ceftazidime (30 µg), cefotaxime (30 µg), amoxicillin- clavulanic acid (10/ 100 µg ratio) nalidixic acid (30 µg), tetracycline (30 µg), ciprofloxacin (10 µg), SXT (sulphamethoxazole -30 µg trimethoprim -5.2 µg), streptomycin (25 µg), gentamycin (10 µg) and chloramphenicol (30 µg) was carried out using Kirby-Bauer disc diffusion method. AST results revealed susceptibility to tetracycline, which is the drug of choice in Kenya administered as doxycycline during cholera outbreaks, among all isolates. Resistance to βeta-lactams and ciprofloxacin emerged in latter years while a decline in resistance to SXT, Chloramphenicol and Streptomycin was noted. This study gave a clear indication that there were changes in the resistance patterns whereby resistance to some antimicrobials declined and others emerged over the ten year period. In order to slow down the emergence and spread of resistance strains, care should be taken by health professionals when prescribing antimicrobials to patients suffering from cholera disease and should be restricted to only severe cases. It is also recommended that antimicrobial susceptibility testing should be done before giving antimicrobials in management of cholera cases.
Keywords: Antimicrobial resistance, Evolution, Kenya, Vibrio cholera.
Title: Trends in Antibiotic Resistance of Vibrio Cholerae Isolates in Kenya (2006 - 2015)
Author: Penina Muthoni Kung’u, Samuel Njoroge, John Kiiru, Paul Okemo, Samuel Kariuki
ISSN 2349-7823
International Journal of Recent Research in Life Sciences (IJRRLS)
Paper Publications
Atlanta Botanical Garden Science Cafe: Medicines from Nature - 2014Cassandra Quave
In 2014, Dr. Quave presented a Science Cafe talk at Atlanta Botanical Gardens: "Medicines From Nature: Adventures of a Medical Ethnobotanist"
Abstract:
Ethnobotany is the study of human interactions with plants. It has perhaps been best defined as the science of survival as it involves the study of plants used in our daily lives for food, medicine, shelter, art, and much more. In this science café, Dr. Quave will discuss her research on medicinal plants for the treatment of infectious disease. From remote regions of the Amazon to volcanic islands in the Mediterranean and isolated mountains in the Balkans, Quave has conducted fieldwork in some of the most biologically diverse regions of the planet. She will share some of her adventures as a medical ethnobotanist and explain how traditional knowledge may be the key to the discovery of new life-saving medicines.
Review of literature on carbon nanotubes exposure risks to human health, and hypes involved in exageration of risks and raising issues regarding research carried out in unrealistic laboratory environment that exhibit excess of human uptake.
Use of Biotechnology in beef cattle production for improving cattle health an...Rashed Hasan Nayeem
Any technological application that uses biological systems, living organisms,or derivatives thereof, to make or modify products or processes for specific
use.
Rapid identification of dermatophyte species by 28S rDNA Polymerase Chain Rea...iosrjce
IOSR Journal of Dental and Medical Sciences is one of the speciality Journal in Dental Science and Medical Science published by International Organization of Scientific Research (IOSR). The Journal publishes papers of the highest scientific merit and widest possible scope work in all areas related to medical and dental science. The Journal welcome review articles, leading medical and clinical research articles, technical notes, case reports and others.
El lunes 23 de octubre de 2017 celebramos una jornada en la Fundación Ramón Areces sobre Microbiota Intestinal: Implicaciones en la Salud y Enfermedad.
Trends in Antibiotic Resistance of Vibrio Cholerae Isolates in Kenya (2006 - ...paperpublications3
Abstract: The evolution of antibiotic resistance was studied among revived Vibrio cholerae strains which were previously archived at -800c between 2006 and 2015. Antibiotic susceptibility testing (AST) on 12 antimicrobials; ampicillin (10µg), cefpodoxime (10 µg), ceftazidime (30 µg), cefotaxime (30 µg), amoxicillin- clavulanic acid (10/ 100 µg ratio) nalidixic acid (30 µg), tetracycline (30 µg), ciprofloxacin (10 µg), SXT (sulphamethoxazole -30 µg trimethoprim -5.2 µg), streptomycin (25 µg), gentamycin (10 µg) and chloramphenicol (30 µg) was carried out using Kirby-Bauer disc diffusion method. AST results revealed susceptibility to tetracycline, which is the drug of choice in Kenya administered as doxycycline during cholera outbreaks, among all isolates. Resistance to βeta-lactams and ciprofloxacin emerged in latter years while a decline in resistance to SXT, Chloramphenicol and Streptomycin was noted. This study gave a clear indication that there were changes in the resistance patterns whereby resistance to some antimicrobials declined and others emerged over the ten year period. In order to slow down the emergence and spread of resistance strains, care should be taken by health professionals when prescribing antimicrobials to patients suffering from cholera disease and should be restricted to only severe cases. It is also recommended that antimicrobial susceptibility testing should be done before giving antimicrobials in management of cholera cases.
Keywords: Antimicrobial resistance, Evolution, Kenya, Vibrio cholera.
Title: Trends in Antibiotic Resistance of Vibrio Cholerae Isolates in Kenya (2006 - 2015)
Author: Penina Muthoni Kung’u, Samuel Njoroge, John Kiiru, Paul Okemo, Samuel Kariuki
ISSN 2349-7823
International Journal of Recent Research in Life Sciences (IJRRLS)
Paper Publications
Atlanta Botanical Garden Science Cafe: Medicines from Nature - 2014Cassandra Quave
In 2014, Dr. Quave presented a Science Cafe talk at Atlanta Botanical Gardens: "Medicines From Nature: Adventures of a Medical Ethnobotanist"
Abstract:
Ethnobotany is the study of human interactions with plants. It has perhaps been best defined as the science of survival as it involves the study of plants used in our daily lives for food, medicine, shelter, art, and much more. In this science café, Dr. Quave will discuss her research on medicinal plants for the treatment of infectious disease. From remote regions of the Amazon to volcanic islands in the Mediterranean and isolated mountains in the Balkans, Quave has conducted fieldwork in some of the most biologically diverse regions of the planet. She will share some of her adventures as a medical ethnobotanist and explain how traditional knowledge may be the key to the discovery of new life-saving medicines.
Review of literature on carbon nanotubes exposure risks to human health, and hypes involved in exageration of risks and raising issues regarding research carried out in unrealistic laboratory environment that exhibit excess of human uptake.
Use of Biotechnology in beef cattle production for improving cattle health an...Rashed Hasan Nayeem
Any technological application that uses biological systems, living organisms,or derivatives thereof, to make or modify products or processes for specific
use.
Rapid identification of dermatophyte species by 28S rDNA Polymerase Chain Rea...iosrjce
IOSR Journal of Dental and Medical Sciences is one of the speciality Journal in Dental Science and Medical Science published by International Organization of Scientific Research (IOSR). The Journal publishes papers of the highest scientific merit and widest possible scope work in all areas related to medical and dental science. The Journal welcome review articles, leading medical and clinical research articles, technical notes, case reports and others.
The current pandemic shows us what happens if pathogens become easily transmissible from human to human, even if the mortality rate of a virus is relatively low. In view of this fact, it is almost unbelievable that since more than ten years, highly risky “gain-of-function” experiments are being conducted in various research labs where dangerous pathogens, such as avian influenza viruses and SARS-type viruses, are being adapted to human cells so that they ultimately become dangerous, i.e. potentially pandemic pathogens. Such experiments are ongoing – even with much more dangerous types of viruses – and, at least partially funded by taxpayers’ money. It is the responsibility of scientists worldwide to raise awareness about these huge risks among politicians and among the general public. A group of 50 scientists from different scientific disciplines and from various countries in Europa, America, Asia, Australia and New Zealand have drafted and signed the „Hamburg Declaration 2022“ with the goal of a worldwide ban of „gain-of-function” research with potentially pandemic pathogens as well as its supervision and continuous monitoring by an independent international regulatory agency. This Declaration follows the spirit of the “Göttinger Declaration of 1957” devoted to the threat by nuclear weapons
The aim of the study was to evaluate the antibacterial evaluation of root extracts of Juglans regia against Extended Spectrum Beta Lactamase (ESBL) producing E. coli and Klebsiella pneumonia in Bombay Hospital and Research Centre Jabalpur. The antibacterial activity of, ethyl acetate and methanol root extracts of Juglans regia was determined by disk diffusion method. The antibacterial activity was calculated based on the minimum inhibitory concentration using Mueller–Hinton broth in a tube-dilution method. The best antibacterial activity, calculated as minimum inhibitory concentration values, against ESBL was shown by the methanol root extract Juglans regia (25 mg/mL) for both isolated organisms and ethyl acetate (25mg/mL) against E. coli. The methanol extract showed zone of inhibition in the range of 17-26mm as compared to ethyl acetate extract which showed zone of inhibition in the range of 11-16mm against the uropathogens. The zone of inhibition ranged from 17 mm to 26 mm and MIC was 25mg/ml. This effect is comparable to antibiotics. The results obtained in the present study suggest that Juglans regia have the potential to be developed as antibacterial agents against ESBL producing UTI bacteria strain. Further investigations are needed to identify the active compounds and their mechanism of action
Jacques Benveniste - A TRUE LEGEND AMONG MYTHSAnton Fedorenko
The above presented materials stand as a foundation for the justification of Jacques Benveniste and his research discoveries within the fields of biological and physical properties of water and the transfer of signals from biologically active substances are actual and attested. The implications of this natural phenomena have vast applications in multiple areas of human activity; and in particular, already are used in healthcare.
Jacques Benveniste The Outstanding French Scientist, was far ahead of his time and has made one of the greatest scientific breakthroughs in recorded history.
In the visage of our beloved science, the time is now upon us to restore justice by giving tribute to a man who has devoted himself wholeheartedly and suffered for his beliefs. Please join us in our righteous efforts by signing onto our international initiative group. Our main initiative is the restoration of the honest name Jacques Benveniste.
Subchronic Inhalation Exposure of Rats to Libby Amphibole and Amosite Asbesto...EPL, Inc.
“Subchronic Inhalation Exposure of Rats to Libby Amphibole and Amosite Asbestos: Effects at 18 Months Post Exposure.” Willson GA (presenter), Dodd DA, Roberts KC, Wall HG, Jarabek AM, Gavett SH. The 33rd Society of Toxicologic Pathology Annual Meeting. Washington, DC. June 22-26, 2014.
“Subchronic Inhalation Exposure of Rats to Libby Amphibole and Amosite Asbestos: Effects at 18 Months Post Exposure.” Dodd DA (presenter), Willson GA, Roberts KC, Wall HG, Jarabek AM, Gavett SH. The 53rd Annual Society of Toxicology Meeting. Phoenix, AZ. March 23-27, 2014.
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The epidemiology of schistosomiasis the Basrah study 2 serological profile.pdfAlim A-H Yacoub Lovers
Yacoub AA, Southgate BA, Lillywhite JE. The epidemiology of schistosomiasis in the later stages of a control program based on chemotherapy: the Basra study. 2. The serological profile and the validity of the ELISA in seroepidemiological studies. Transactions of the Royal Society of Tropical Medicine and Hygiene 1987 May;81(3):460-7.
Antibiogram of Bacterial Isolates at Hail General Hospital, KSA June 1 – Dece...iosrjce
This research study focused on the antibiogram of bacterial isolates at Hail General Hospital,
Kingdom of Saudi Arabia. It sought to answer the following questions: (1) What is the percentage distribution of
the isolates on the specimens when classified according to the following bacteria? Enterobacter aerogenes,
Enterobacter cloacae, Escherichia coli, Klebsiella pneumoniae, Proteus spp., Pseudomonas aeruginosa,
Raoultella (K.) ornithinolytica. (2) What is the antibiogram result of the bacterial isolates? Descriptive research
using content analysis was employed wherein the Automated Sensitivity Testing Machine data obtained from the
Microbiology section of Hail General Hospital. The statistical tools were frequency and percentage. The results
revealed that based on the percentage distribution of the specimens, the highest number of isolates for
Enterobacter aerogenes, Enterobacter cloacae, Klebsiella pneumoniae and Proteus spp. was from throat swab,
urine for Escherichia coli and Psedomonas aeruginosa, ward swab and high vaginal swab for Raoultella (K.)
ornithinolytica. On antibiogram result, the most sensitive antibiotics for Enterobacter aerogenes was
Meropenem; Cirpofloxacin and Levofloxacin for Enterobacter cloacae; Imipenem for Escherichia coli;
Amikacin for Klebsiella pneumoniae; Ertapenem, Imipenem and Pip/Tazo for Proteus spp.; Pip/Tazo for
Pseudomonas aeruginosa, and Imipenem for Raoultella (K.) ornithinolytica. The most resistant antibiotics for
Enterobacter aerogenes, Escherichia coli, Klebsiella pneumonaie and Raoultella (K.) ornithinolytica was
Ampicillin; Amox/K Clav, Cefazolin and Cefoxitin for Enterobacter cloacae; Cefotaxime for Pseudomonas
aeruginosa and for Proteus spp. was Cefazolin. The researchers recommend for the conduct of an annual
antibiogram study by institution, disseminate the information through seminars/fora especially to clinicians,
conduct another study to include other hospitals and other types of bacteria.
1. PUBLISHED WORK
Dr. rer. nat Sven Korte
I. Citable Posters, Congress Abstracts Research Papers, Book Chapters and Books
1) S.H. KORTE
The abundance of Asterias rubens (LINNAEUS) in the euthrophication gradient of the
Flensburg Fjord – a sublitorale and ecological free land study under special consideration
of possible oxygen deficiency
Diploma, University of Kassel, Germany (1996)
2) S.H. KORTE
A free land study monitoring the population and specific ecological pressure vectors
of the abundance of Asterias rubens (LINNAEUS) in the euthrophication gradient of the Flensburg Fjord
Dissertation, University of Kassel, Germany (1998)
3) P. Nowak, S. Korte, U. Zühlke, A. Wiederhold, B. Niggemann, G. Weinbauer, W. Müller and F. Vogel,
Covance Laboratories GmbH, Kesselfeld 29, D-48163 Münster, Germany.
PROLONGED INFUSION IN MARMOSET MONKEYS: FEASIBILITY OF A PORT-CATHETER
TECHNIQUE
Society of Toxicology, 41th
Annual Meeting, 2002
The Toxicologist, Oxford University Press, Volume 60, Number 1, March 2002
4) U Zühlke, S Korte, B Niggemann, A Fuchs, W Müller, Covance Laboratories GmbH, Kesselfeld 29, D-
48163 Münster, Germany.
THE COMMON MARMOSET (Callithrix jacchus) AS A MODEL IN BIOTECHNOLOGY
13th
Primate Symposium, 26 – 27 February 2002, Münster, Germany
Primate Models in Pharmaceutical Drug Development
Waxmann Verlag GmbH, 2002, Münster, New York, München, Berlin, pp .119-125
5) S Korte, U Zühlke, P Nowak, S Tippkötter, A Wiederhold, B Niggemann, G Weinbauer, W Müller and
F Vogel, Covance Laboratories GmbH, Münster, Germany.
FEASIBILITY OF LONG-TERM CONTINUOUS INTRAVENOUS INFUSION IN UNRESTRAINED
MARMOSET MONKEYS
Society of Toxicology, 42th
Annual Meeting, 2003
The Toxicologist, Oxford University Press, Volume 72, Number S-1, March 2003
6) GF Weinbauer, U Zühlke, S Korte, P Nowak, A Fuchs, W Müller, Covance Laboratories GmbH,
Münster, Germany. THE MARMOSET (CALLITHRIX JACCHUS) AS A PRIMATE MODEL IN
TOXICOLOGY: THE COVANCE EXPERIENCE
Japanese Society of Toxicology, Annual Meeting, 2003
7) S Korte, U Zühlke, J Kaspareit, S Friderichs-Gromoll, W Müller, F Vogel, GF Weinbauer, Covance
Laboratories GmbH, Münster, Germany. REFERENCE CONTROL DATA FOR THE COMMON
MARMOSET (CALLITHRIX JACCHUS): A COMPARISON WITH MACAQUES.
Society of Toxicology, 43th
Annual Meeting, 2004
The Toxicologist, Oxford University Press, Volume 78, Number S-1, March 2004 : page 205
8) B Niggemann, U Korte, S Korte, F Vogel and GF Weinbauer, Covance Laboratories GmbH, Münster,
Germany. OCULAR TOXICITY TESTING IN THE NONHUMAN PRIMATE: INCIDENCES OF
SPONTANEOUS LESIONS IN THE CYNOMOLGUS MONKEY AND THE MARMOSET.
Japanese Society of Toxicology, Annual Meeting, 2004, Osaka, Japan
(9) P Nowak, S Korte, F Vogel, W Müller, Covance Laboratories GmbH, Münster, Germany:
VALIDATION OF A NEWLY INVENTED PORT CATHETER SYSTEM FOR CONTINUOUS INFUSION
STUDIES
Society of Toxicology, 44th
Annual Meeting, 2005
2. The Toxicologist, Oxford University Press, Volume 84, Number S-1, March 2005
(10) S Korte, D Eastman, U Zühlke, GF Weinbauer, Covance Laboratories GmbH, Münster, Germany:
SCREENING STUDIES WITH OILY VEHICLES FOR ORAL DRUG DELIVERY IN THE MARMOSET (CALLITHRIX JACCHUS)
AND THE CYNOMOLGUS (MACACA FASCICULARIS) MONKEY
Society of Toxicology, 45th
Annual Meeting, 2006
The Toxicologist, Oxford University Press, March 2006
(11) S Korte, A Fuchs, G. F. Weinbauer, E. Moscardo and A. Giarola: MODIFIED IRWIN TEST AS DIAGNOSTIC
TOOL TO MONITOR NEUROBEHAVIOURAL CHANGES IN MONKEYS. Annual Meeting of the Safety Pharmacology
SOCIETY (SPS) 2006 IN SAN DIEGO; OCTOBER 2006, USA.
JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
VOLUME 56, ISSUE 2, SEPTEMBER-OCTOBER 2007, PAGE E47
(12) B. NIGGEMANN, S. KORTE, S. SRIVASTAV, W. MÜLLER, GF. WEINBAUER
Ocular Toxicity Testing in Nonhuman Primates
16th
Primate Symposium, 13 – 14 June 2006, Münster, Germany
Novel Approches Towards Primate Toxicology, Waxmann Verlag GmbH, 2006, Münster, New York, München,
Berlin, pp .2002-217
(13) A.FUCHS; S.KORTE, G.F. WEINBAUER
Marmosets (Callithrix jacchus) as model for developmental and reproductive toxicity (DART) evaluation
Society of Toxicology, 46th
Annual Meeting, 2007
The Toxicologist, Oxford University Press, March 2007
(14) High Definition Oscillometry (HDO): A new method for non-invasive blood pressure
measurements in conscious and sedated common marmosets.
Schmelting, Barthel; Egner, Beate; Korte, Sven
H.; Weinbauer, Gerhard; AALAS, 2007
J Am Ass Lab Animal Sci Vol 46(4), 144
(15) Tidal volume and respiratory rate: Evaluation of safety pharmacology aspects in deeply sedated marmoset
monkeys
Sven Korte, Barthel Schmelting, Brian Marshall
Society of Toxicology, 47th
Annual Meeting, 2008
The Toxicologist, Oxford University Press, March 2008
(16) Schmelting B, Egner B, Korte SH, Weinbauer G 2007. Non-invasive blood pressure determination for
continuous anaesthesia monitoring in nonhuman primates. J Am Ass Lab Animal Sci. Vol 47(1), 53
17) Non-invasive blood pressure monitoring in Macaca fascicularis: High Definition Oscillometry versus
implanted telemetric devices.
B Schmelting, M. Niehoff, B Egner, SH Korte, GF Weinbauer
Society of Toxicology, 47th
Annual Meeting, 2008
The Toxicologist, Oxford University Press, March 2008
18) Non-invasive blood pressure determination in Macaca fascicularis and Callithrix jacchus by High Definition
Oscillometry
B Schmelting, M. Niehoff, B Egner, SH Korte, GF Weinbauer
Annual Meeting of the Safety Pharmacology Society (SPS) 2008 in Madison, Wisconsin, USA.
19) Feasibility and variability of testicular volume monitoring in the marmoset monkey (Callitrix jacchus)
GF Weinbauer, S Korte, CM Luetjens
Society of Toxicology, 48th
Annual Meeting, 2009
The Toxicologist Volume 108, Number 1, Oxford University Press, March 2009
20) Feasibility of repeated intra-articular administration in the marmoset monkey (Callitrix jacchus)
S Korte, G.F. Weinbauer
Society of Toxicology, 48th Annual Meeting, 2009
The Toxicologist, Volume 108, Number 1, Oxford University Press, March 2009
3. 21) B. Schmelting , M. Niehoff , B. Egner , S.H. Korte & G.F. Weinbauer
High Definition Oscillometry: a novel technique for non-invasive blood pressure monitoring in the cynomolgus
monkey (Macaca fascicularis)
Journal of Medical Primatology, doi:10.1111/j.1600-26894.2009.00344. 05 March 2009
22) S Korte, GF Weinbauer, A Fuchs, P Nowak
Continuous intravenous infusion in free ranging pregnant cynomolgus monkeys
Covance Laboratories GmbH, Muenster, Germany
ACT 2010
23) S Korte, CM Luetjens, C Rose, GF Weinbauer
Covance Laboratories GmbH, Muenster, Germany
Automated behavioral observations of socially housed cynomolgus monkeys treated with amphetamine and
diazepam
SOT 2010, Salt Lake City
24) S Korte, U Zuehlke, W Müller
Covance Laboratories GmbH, Muenster, Germany
Implementation of ETS 123 Requirements for the Housing of Marmoset Monkeys (Callithrix jacchus) over the
Conduct of Regulatory Required Toxicity Studies
Eurotox 2010
25) G.F. Weinbauer, C. Rose, S. Korte, C.M. Luetjens,
Covance Laboratories GmbH, Muenster, Germany
Quantitative recording of spontaneous locomotor activity in socially housed cynomolgus monkeys
JSOT 2010
26) C Rose*, J.E. van der Harst**, R.C. de Heer**, B.M. Spruijt**, S Korte*
* Covance Laboratories GmbH, Muenster, Germany
** Delta Phenomics BV, Utrecht, The Netherlands
Quantified tracking and monitoring of Diazepam treated socially housed Cynomolgus Monkeys
SOT 2011 Washington DC
27) S Korte, P Nowak, J Kaspareit, S Friderichs-Gromoll, E Buse
Covance Laboratories GmbH, Muenster, Germany
Intravenous continuous infusion studies with implanted port catheter systems in free ranging Cynomolgus
monkeys – a 20 year experience report - 2011
SOT 2011 Washington DC
28) First in Monkey (FIM) performed tracking of magnetic capsule inside the gastrointestinal tract with 3D-
MAGMA
H. Richert**, S. Korte*, S. Abert**,
*Covance Laboratories GmbH, Muenster, Germany, **Matesy GmbH, Jena, Germany
SOT 2011
29) Quantified tracking and monitoring of diazepam treated socially housed cynomolgus monkeys.
Rose C, de Heer RC, Korte S, van der Harst JE, Weinbauer GF, Spruijt BM.
Regul Toxicol Pharmacol. 2011 Oct 23. [Epub ahead of print]
PMID:
22051156
[PubMed - as supplied by publisher]
30) ITO Proceedings: A European Perspective of Best Practice in NHP Intravenous Infusion Models
SH Korte(1), P Nowak(1), AN Alexander(2), AM Brooks(2)
(1) Covance Laboratories GmbH, Münster, Germany
(2) Covance Laboratories Inc., Madison, Wisconsin, USA
31) ITO Proceedings: Feasibility of continuous and prolonged intravenous infusion in freely moving pregnant
cynomolgus monkeys
SH Korte(1), A Brooks(2), A Alexander(2), P Nowak(1), A Fuchs(1), GF Weinbauer(1)
4. (1)
Covance Laboratories GmbH, Münster, Germany
(2)
Covance Laboratories Inc, Madison, USA
32) Korte S, Nowak P, Luft J, Niggemann B (2014): The Marmoset. In: O Green, G Healing (Eds.) Non-Clinical
Vascular Infusion Technology, Volume II, CRC Press, Taylor & Francis Group, Boca Raton, London, New
York, p285-306.
33) SOT 2012 San Fransisco, USA: Computer tomography in non human primates. A feasibility study for pre-
clinical safety evaluation in geriatric cynomolgus monkeys
S Korte 1), M Wozniak 2), B Niggemann 1)
34) SOT 2012 San Fransisco, USA: Prolonged and continuous intravenous infusion toxicity studies in the
marmoset monkey using a port catheter system
P Nowak, S Korte, B Niggemann and J Luft
Covance Laboratories GmbH, Muenster, Germany
35) JSOT 2012 Cynomolgus monkey background data from lumbar and cisterna magna CSF collection.
W Frings, S Korte, B Niggemann
36) ACT 2012, Orlando, USA: REFERENCE CONTROL DATA FOR THE COMMON MARMOSET
(CALLITHRIX JACCHUS): A COMPARISON WITH MACAQUES.
S Korte, B Niggemann
37) ACT 2012, Orlando, USA: Continuous ambulatory intrathecal infusion study in the cynomolgus monkey:
The outcome of unexpected adverse effects in vehicle (L-arginine) treated control animals
S Korte, B Niggemann
38) SOT 2013: 12 week intrathecal administration study in port catheterized juvenile cynomolgus monkeys. S
Korte, M Butt, C Rose, M Niehoff
39) SOT 2013: Surgical alternatives for multiple CSF sampling in conscious cynomolgus monkeys: a novel
approach. J Sternberg, S Korte, C Rose
40) SOT 2013: Feasibility study of EEG measurements in chair restrained cynomolgus monkeys. Rose C., Korte
S and Niggemann B.
41) SOT 2013: Body weight changes in mice during restrained intravenous bolus versus continuous infusion.
van Wijk H, Brooks A, Korte, S, Alexander, A
42) "DIFFERENTIAL RESPONSES TO JNJ-37822681, A SPECIFIC AND FAST DISSOCIATING
DOPAMINE D2 RECEPTOR ANTAGONIST, IN CYNOMOLGUS MONKEY AND SPRAGUE DAWLEY
RAT GENERAL TOXICOLOGY STUDIES: CLINICAL OBSERVATIONS, PROLACTIN LEVELS,
MAMMARY HISTOPATHOLOGY FINDINGS AND TOXICOKINETICS" J. Appl. Toxicol. (2013)
Eric J. de Waal, Maria Desmidt, Sven Korte, Marc Niehoff, Kevan Chase, Wayne Arrowsmith, Ann Lampo
43) ACT 2013: Evaluation of Pachymetry Data for the Measurement of Corneal Thickness in Cynomolgus
Monkeys. S. Korte, C.M. Luetjens and B. Niggemann
44) ACT 2013: A Feasibility Project: Long-Term Intraventricular CSF Sampling in a Cynomolgus Monkey
Via a Port Catheter System. S. Korte, J. Sternberg, C. Rose, B. Niggemann and W. Frings
45) SOT 2014: Dermal administration in toxicity studies using the cynomolgus monkey. Korte, S., Niggemann,
B.
46) SOT 2014: Surgical and non-surgical options for dosing of centrally administered compounds and CSF
sampling in toxicity studies using cynomolgus monkeys. Rose, C., Korte, S., Runge F., Niggemann, B.
(47) SOT 2014: Comparison of cynomolgus and marmoset monkeys for pre-clinical testing of
biopharmaceuticals. Frings, Korte, Niggemann
5. (48) SOT 2015: Diagnostic magnetic resonance imaging in the scope of biologics safety assessment in
nonhuman primates – A case of spontaneous obstructive pancreatic necrosis and pyloric stenosis in a
cynomolgus monkey. Korte, S., Wozniak, M., Runge, F., Kaspareit, J, Mecklenburg, L.
(49) ACT 2015: Method Enhancement for Intrathecal lumbar bolus delivery and CSF sampling in the
anesthetized cynomolgus monkey for the safety Assessment of Oligonucleotides. S KORTE , K. RASMUSSEN,
S GROTE-WESSELS, R MILLOTT-VON LAER, A VON KEUTZ, F RUNGE
(50) ACT 2015: Standardized Neurological and Physical Diagnostics during Intrathecal Drug Delivery of
Cynomolgus Monkeys: You Better Know the Background Findings. S KORTE, MO NIEHOFF, A VON
KEUTZ, F RUNGE
(51) Book editor: The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment (2015),
Edition: 1st Edition, Publisher: Academic Press, Elsevier, Editors: Blümel J, Korte S, Schenck E, Weinbauer GF,
pp.3-16
(52) Book chapter: Considering the Use of Callithrix jacchus Chapter 23; Luetjens CM, Kaspareit J, Korte S,
Wistuba J; in book: The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment, Edition
(2015): 1st Edition, Publisher: Academic Press, Elsevier, Editors: Blümel J, Korte S, Schenck E, Weinbauer GF,
pp.3-16.
(53) Book chapter: Study Design Considerations, technical procedural aspects, scheduling, and dosing sampling
volumes; W FRINGS, M NIEHOFF, S KORTE; in book: The Nonhuman Primate in Nonclinical Drug
Development and Safety Assessment, Edition (2015): 1st Edition, Publisher: Academic Press, Elsevier, Editors:
Blümel J, Korte S, Schenck E, Weinbauer GF, pp.3-16.
(54) Book chapter: Basic Physiology of Callithrix jacchus; K MÄTZ-RENSING, S KORTE; in book: The
Nonhuman Primate in Nonclinical Drug Development and Safety Assessment, Edition (2015): 1st Edition,
Publisher: Academic Press, Elsevier, Editors: Blümel J, Korte S, Schenck E, Weinbauer GF, pp.3-16.
(55) Book chapter: Gaps and Future Challenges; J BLUEMEL, S KORTE, E SCHENCK, GF WEINBAUER; in
book: The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment, Edition (2015): 1st
Edition, Publisher: Academic Press, Elsevier, Editors: Blümel J, Korte S, Schenck E, Weinbauer GF, pp.3-16.
(56) Book chapter: Juvenile Toxicity Testing: experience Using Nonhuman Primate Models; Gerhard F.
Weinbauer, Sven H. Korte; in . Gerhard F. Weinbauer, Friedhelm Vogel (Eds.)
Primate Biologics Research at a Crossroads; 2015, 174 Seiten, E-Book (PDF), ISBN 978-3-8309-7961-6
(57) Book chapter: Marmoset, S Korte, P Nowak, J Luft, B Niggemann; in book; Non-Clinical Vascular Infusion
Technology, Volume II: The Techniques (2013); Owen P. Green, Guy Healing (Eds.); December 26, 2013 by
CRC Press , SBN 9781439874455 - CAT# K13451.
(58) SOT 2016: Diagnostic Tools to Enhance Long-Term Intrathecal Delivery Studies in Nonhuman Primates. S.
Korte, M.O. Niehoff and F.T. Ludwig, Covance Preclinical Services GmbH, Münster, Germany.
(59) SOT 2016: Long-Term Intrathecal Bolus Administration Studies in Cynomolgus Monkeys:
Expected Background Findings, Procedure-Related Observations and Recommended Procedures. M.O. Niehoff,
S. Korte and F.T. Ludwig, Covance Preclinical Services GmbH, Münster, Germany.
(60) SOT 2016: Emerging Biologics Development Methods: Free-Ranging Cynomolgus Monkeys Undergoing
Continuous Intravenous Infusion with an Implanted Port Catheter System–A Method Transfer in Courtesy
to the “Refinement” in the 3 Rs. C. Miller1, S. Korte2, A. Salva1, N. Snippe2, F. Runge2 and H. vanWijk1 : 1.
Covance Laboratories, Harrogate, UK; 2. Covance Preclinical Services, GmbH, Münster, Germany.
(61) Korte S, Vuillemont BR, Wright TL, Adams EL, Boyd R, Butt MT; Tox Sci 2016. Safety evaluation of
CNS administered biologics - study design, data interpretation, and translation to the clinics.
(62) ESTP 2016: S. Friderichs-Gromoll, S. Korte, J. Kaspareit, T. Pfaff: Always know your vehicle: Sulfuric-
acid based vehicle induced nephrotoxicity and pancreas toxicity in Cynomolgus Monkeys.
6. (63) ACT 2016. Korte S1), Wozniak M2), Runge F1), Voß T1), v. Keutz A1): Enhanced imaging has proven to
be a safety net during the conduct of regulatory studies with nonhuman primates: The value of hard data before
necropsy
II. Invited Lectures and Oral Presentations
1) Invited Speaker European Marmoset Research Group (EMRG), Paris, France, 2002
2) Invited Speaker EMRG – Barcelona, Spain 2006
4) Session Chair SOT 2011, Washington DC, USA
5) Invited Speaker ITO (infusion Technical Organisation), Barcelona, Spain, 2012
6) Session Chair SOT 2012, San Fransisco, USA
7) Invited Speaker SOT 2012, San Fransisco, USA
8) Invited Speaker juv. Tox symposium Beerse, Belgium 2013
9) Invited speaker European Primate Veterinarians, Göttingen, Germany, 2013
10) Session Chair SOT 2014, Phoenix, USA, 2014
11) Speaker Safety Pharamcology Session: Quantitative behavioral monitoring of socially housed
cynomolgus monkey, SOT 2014, Phoenix, USA.
12) Symposium session chair and invited speaker, ACT (American Colleague of Toxicology),
Orlando, USA, 2014
13) ITO , Harrogate NY, UK, 2014
14) CE course chair and invited speaker, SOT, San Diego, USA, 2015
15) Invited Speaker ITO (infusion Technical Organisation), Cologne, Germany, 2015
16) Sponsor Exhibitor Session Speaker, New Orleans, SOT 2016
7. (63) ACT 2016. Korte S1), Wozniak M2), Runge F1), Voß T1), v. Keutz A1): Enhanced imaging has proven to
be a safety net during the conduct of regulatory studies with nonhuman primates: The value of hard data before
necropsy
II. Invited Lectures and Oral Presentations
1) Invited Speaker European Marmoset Research Group (EMRG), Paris, France, 2002
2) Invited Speaker EMRG – Barcelona, Spain 2006
4) Session Chair SOT 2011, Washington DC, USA
5) Invited Speaker ITO (infusion Technical Organisation), Barcelona, Spain, 2012
6) Session Chair SOT 2012, San Fransisco, USA
7) Invited Speaker SOT 2012, San Fransisco, USA
8) Invited Speaker juv. Tox symposium Beerse, Belgium 2013
9) Invited speaker European Primate Veterinarians, Göttingen, Germany, 2013
10) Session Chair SOT 2014, Phoenix, USA, 2014
11) Speaker Safety Pharamcology Session: Quantitative behavioral monitoring of socially housed
cynomolgus monkey, SOT 2014, Phoenix, USA.
12) Symposium session chair and invited speaker, ACT (American Colleague of Toxicology),
Orlando, USA, 2014
13) ITO , Harrogate NY, UK, 2014
14) CE course chair and invited speaker, SOT, San Diego, USA, 2015
15) Invited Speaker ITO (infusion Technical Organisation), Cologne, Germany, 2015
16) Sponsor Exhibitor Session Speaker, New Orleans, SOT 2016