Kidneys are the chief excretory organs of the body. They excrete the unwanted nitrogenous substances through urine. The chief nitrogenous wastes that are excreted through urine are Kidneys also excrete harmful substances like toxins, drugs, heavy metals. By excreting the waste materials through urine, the kidneys maintain homeostasis of the body. Urine formation: Urine is formed by the absorption of some substances into the blood and secretion of some substances into the lumen of renal tubules. This process of urine formation occurs starting from the glomerulus, Bowman’s capsule, along the renal tubule into the collecting duct. Urine formation involves three main processes. They are: Glomerular filtration: Net filtration pressure = glomerular capillary pressure - osmotic pressure + hydrostatic pressure. The filtrate enters the Bowman’s capsule and then into the renal tubule of nephron. Tubular reabsorption: As the substances are selectively reabsorbed into the blood, this reabsorption is also known as selective reabsorption. Tubular secretion: Thus, urine is formed by glomerular filtration, tubular reabsorption, and tubular secretion. Excretory substances are secreted into the lumen of renal tubules. Useful substances are reabsorbed into the capillaries surrounding the renal tubules. Solution Kidneys are the chief excretory organs of the body. They excrete the unwanted nitrogenous substances through urine. The chief nitrogenous wastes that are excreted through urine are Kidneys also excrete harmful substances like toxins, drugs, heavy metals. By excreting the waste materials through urine, the kidneys maintain homeostasis of the body. Urine formation: Urine is formed by the absorption of some substances into the blood and secretion of some substances into the lumen of renal tubules. This process of urine formation occurs starting from the glomerulus, Bowman’s capsule, along the renal tubule into the collecting duct. Urine formation involves three main processes. They are: Glomerular filtration: Net filtration pressure = glomerular capillary pressure - osmotic pressure + hydrostatic pressure. The filtrate enters the Bowman’s capsule and then into the renal tubule of nephron. Tubular reabsorption: As the substances are selectively reabsorbed into the blood, this reabsorption is also known as selective reabsorption. Tubular secretion: Thus, urine is formed by glomerular filtration, tubular reabsorption, and tubular secretion. Excretory substances are secreted into the lumen of renal tubules. Useful substances are reabsorbed into the capillaries surrounding the renal tubules..