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Keratosis obturans & primary auditory 
canal cholesteatoma 
Definitions: Keratosis obturans & primary auditory canal choleateatoma are different clinical & 
pathological entities. In the 1980, they are defined as different entities.before that this was not 
clear. 
Keratosis obturans is the accumulation of a large plug of desquaminated keratin in the external 
auditory meatus. 
Primary auditory canal cholesteatoma is the invasion of squamous tissues from the ear into a 
localized area of bony erosion. 
Pathology 
In keratosis obturans a geometrically patterned keratin plug within lumen of an expanded external 
auditory canal is seen. The keratin are shed from the circumference of the deep ear canal forming a 
lamina (onion skin arrangement). 
In primary auditory canal cholesteatoma , the keratin is derived primarily from a sac that involves 
the bone of the ear canal with bony fragments within it & random keratin in the lumen of the ear 
canal. 
Keratosis obturans Primary auditory canal 
cholesteatoma 
Aetiology Abnormal epithelial migration, 
more than one disease. 
Abnormal bone leading to 
migration of epithelium into 
this bone. 
Symptoms/signs Severe otalgia,conductive 
hearing loss, younger ages , 
occasionally bilateral,associated 
with lung & sinus disease, can 
present with a plugged feeling. 
Chronic otorrhoea with normal 
hearing, itchiness, or pain. 
Older populations, usually 
unilateral. 
Pathology Keratin plug occluding canal , 
TM thicken& standing out in 
relief in a widened ear canal. 
Ear canal grossly widen or 
ballooned. Can cause extensive 
bony erosion including 
automastoidectomy.Hyperaemia 
of the ear canal with 
Keratin in random pattern 
TM normal 
Localised osteitis/ erosion of 
the canal usually 
posterioinferior, 
Sequestration of bone.
granulations. 
Treatment Removal of plug 
Local treatment of granulations 
Biopsy to exclude 
malignancy/necrotizing otitis 
externa. 
May need continued cleanings. 
Surgically remove 
cholesteatoma & abnormal 
bone , 
Graft with fascia 
Biopsy . 
D/D Impacted wax with infection, 
Neoplastic disease. 
Necrotizing otitis externa, 
Benign sequestrum, 
Neoplastic disease. 
Management options 
The pain & deafness associated with keratosis obturans means that it is necessary to remove it often 
under G/A. Canaloplasty has been suggested for recurrent keratosis obturans with good results. 
Primary auditory canal cholesteatoma ,conservative treatment is used where the extent of the 
cholesteatoma erosion can be seen. When this is not possible , patients are treated with excision of 
necrotic bone &cholesteatoma via the mastoid & repair of the defect using temporal fascia.

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Keratosis obturans & primary auditory canal cholesteatoma

  • 1. Keratosis obturans & primary auditory canal cholesteatoma Definitions: Keratosis obturans & primary auditory canal choleateatoma are different clinical & pathological entities. In the 1980, they are defined as different entities.before that this was not clear. Keratosis obturans is the accumulation of a large plug of desquaminated keratin in the external auditory meatus. Primary auditory canal cholesteatoma is the invasion of squamous tissues from the ear into a localized area of bony erosion. Pathology In keratosis obturans a geometrically patterned keratin plug within lumen of an expanded external auditory canal is seen. The keratin are shed from the circumference of the deep ear canal forming a lamina (onion skin arrangement). In primary auditory canal cholesteatoma , the keratin is derived primarily from a sac that involves the bone of the ear canal with bony fragments within it & random keratin in the lumen of the ear canal. Keratosis obturans Primary auditory canal cholesteatoma Aetiology Abnormal epithelial migration, more than one disease. Abnormal bone leading to migration of epithelium into this bone. Symptoms/signs Severe otalgia,conductive hearing loss, younger ages , occasionally bilateral,associated with lung & sinus disease, can present with a plugged feeling. Chronic otorrhoea with normal hearing, itchiness, or pain. Older populations, usually unilateral. Pathology Keratin plug occluding canal , TM thicken& standing out in relief in a widened ear canal. Ear canal grossly widen or ballooned. Can cause extensive bony erosion including automastoidectomy.Hyperaemia of the ear canal with Keratin in random pattern TM normal Localised osteitis/ erosion of the canal usually posterioinferior, Sequestration of bone.
  • 2. granulations. Treatment Removal of plug Local treatment of granulations Biopsy to exclude malignancy/necrotizing otitis externa. May need continued cleanings. Surgically remove cholesteatoma & abnormal bone , Graft with fascia Biopsy . D/D Impacted wax with infection, Neoplastic disease. Necrotizing otitis externa, Benign sequestrum, Neoplastic disease. Management options The pain & deafness associated with keratosis obturans means that it is necessary to remove it often under G/A. Canaloplasty has been suggested for recurrent keratosis obturans with good results. Primary auditory canal cholesteatoma ,conservative treatment is used where the extent of the cholesteatoma erosion can be seen. When this is not possible , patients are treated with excision of necrotic bone &cholesteatoma via the mastoid & repair of the defect using temporal fascia.